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... have been obtained that either increase or decrease its efficiency of initiating transcription. Base substitutions that make the promoter sequence more similar to the consensus generate a stronger promoter (promoter "up" mutations) whereas those that make the promoter less similar to the consensus g ...
... have been obtained that either increase or decrease its efficiency of initiating transcription. Base substitutions that make the promoter sequence more similar to the consensus generate a stronger promoter (promoter "up" mutations) whereas those that make the promoter less similar to the consensus g ...
Gene Section XPC (xeroderma pigmentosum, complementation group C) Atlas of Genetics and Cytogenetics
... damaged site. The XPC-HR23B complex is only required for global genome repair. In case of transcription coupled repair when an RNA polymerase is stalled at a lesion, the DNA is unwound by the transcription complex and XPA can bind independently of XPC-HR23B complex. ...
... damaged site. The XPC-HR23B complex is only required for global genome repair. In case of transcription coupled repair when an RNA polymerase is stalled at a lesion, the DNA is unwound by the transcription complex and XPA can bind independently of XPC-HR23B complex. ...
TimeClust: a clustering tool for gene expression time series
... performed different experiments in which they used cDNA microarrays to measure gene expression values at different time points along the cell cycle. In one of these, they measured the log2 Cy5 of gene expression at 26 time points over 44 hours using microarrays Cy3 containing about 42000 clones. Mor ...
... performed different experiments in which they used cDNA microarrays to measure gene expression values at different time points along the cell cycle. In one of these, they measured the log2 Cy5 of gene expression at 26 time points over 44 hours using microarrays Cy3 containing about 42000 clones. Mor ...
Changing Patterns of Gene Regulation in the Evolution of Arthropod
... grammatic representation of some of the gene net- ah, 1989; Fig. 1). works involved in Drosophila A/P, DA7 and P/D axis This description is, of course, an overformation. Details are described in the text, bed: bi- simplified version of embryonic patterning. coicl; Dll: Distal-less; dpp: decapentaple ...
... grammatic representation of some of the gene net- ah, 1989; Fig. 1). works involved in Drosophila A/P, DA7 and P/D axis This description is, of course, an overformation. Details are described in the text, bed: bi- simplified version of embryonic patterning. coicl; Dll: Distal-less; dpp: decapentaple ...
An Interaction-Dependent Model for Transcription Factor Binding
... interaction-dependent functionality is the basis for transcriptional modules [7-9]. In some cases, this dependency is involved in protein modifications, like phosphorylation. However, there are other cases where the binding of the TF itself is interaction-dependent [10, 11]. This interaction-depende ...
... interaction-dependent functionality is the basis for transcriptional modules [7-9]. In some cases, this dependency is involved in protein modifications, like phosphorylation. However, there are other cases where the binding of the TF itself is interaction-dependent [10, 11]. This interaction-depende ...
Conclusions Synapsin IIa is expressed in the brain of adult zebrafish
... •Synapsins and synapsin-like genes have been characterized in a variety of invertebrates and vertebrates, however the synapsin genes have yet to be characterized in zebrafish. ...
... •Synapsins and synapsin-like genes have been characterized in a variety of invertebrates and vertebrates, however the synapsin genes have yet to be characterized in zebrafish. ...
A.3.1.5SecretsInGenes - Life Science Academy
... A logarithm is the power to which a base must be raised to produce a desired value. In the case of a base 2 logarithm, for every increase or decrease of one, there is a two fold change. For example: Log2(0.0625) = -4 Log2(0.125) = -3 Log2(0.25) = -2 Log2(0.5) = -1 Log2(1) = 0 Log2(2) = 1 Log2(4) = 2 ...
... A logarithm is the power to which a base must be raised to produce a desired value. In the case of a base 2 logarithm, for every increase or decrease of one, there is a two fold change. For example: Log2(0.0625) = -4 Log2(0.125) = -3 Log2(0.25) = -2 Log2(0.5) = -1 Log2(1) = 0 Log2(2) = 1 Log2(4) = 2 ...
Full Article - Pertanika Journal
... Banana is one of the important global food commodities. The commercial and subsistence production is seriously threatened by Fusarium wilt caused by soilborne Fusarium oxysporum f. sp. cubense (Foc). Foc race 4 (FocR4) is considered economically important as it causes significant plantation losses i ...
... Banana is one of the important global food commodities. The commercial and subsistence production is seriously threatened by Fusarium wilt caused by soilborne Fusarium oxysporum f. sp. cubense (Foc). Foc race 4 (FocR4) is considered economically important as it causes significant plantation losses i ...
Interplay between the transcription factors acting on
... expression of the genes that form the UGA regulon is inducible by GABA and sensitive to nitrogen catabolite repression (NCR). GABA induction of these genes is mediated by Uga3 and Dal81 transcription factors, whereas GATA factors are responsible for NCR. Here, we show how members of the UGA regulon ...
... expression of the genes that form the UGA regulon is inducible by GABA and sensitive to nitrogen catabolite repression (NCR). GABA induction of these genes is mediated by Uga3 and Dal81 transcription factors, whereas GATA factors are responsible for NCR. Here, we show how members of the UGA regulon ...
file - ORCA - Cardiff University
... will access sequence space beyond that sampled by simple gene point mutations that ultimately restrict sequence, structural and functional diversity (1, 5, 6). Sampling randomly introduced point mutations severely limits the amino acid range that can be tested at a particular residue position as sta ...
... will access sequence space beyond that sampled by simple gene point mutations that ultimately restrict sequence, structural and functional diversity (1, 5, 6). Sampling randomly introduced point mutations severely limits the amino acid range that can be tested at a particular residue position as sta ...
AL22229235
... numbers of cancer victims are increasing steadily, the necessity of the cancer classification techniques has become indispensible. For the above impenetrability and to obtain better consequences of the system with accuracy a new learning algorithm called Extreme Learning Machine (ELM) is used. ELM o ...
... numbers of cancer victims are increasing steadily, the necessity of the cancer classification techniques has become indispensible. For the above impenetrability and to obtain better consequences of the system with accuracy a new learning algorithm called Extreme Learning Machine (ELM) is used. ELM o ...
A newly discovered human -globin gene
... adult blood). Platelets were removed from the samples by lowspeed centrifugation, and nucleated cells were removed by leukocyte reduction filtering. Samples were analyzed using Affymetrix from HG-U133 A and B chips, and the expression of 44 229 probe sets was ranked. The focus of this report is the ...
... adult blood). Platelets were removed from the samples by lowspeed centrifugation, and nucleated cells were removed by leukocyte reduction filtering. Samples were analyzed using Affymetrix from HG-U133 A and B chips, and the expression of 44 229 probe sets was ranked. The focus of this report is the ...
S3 Text.
... We used a mixture model algorithm implemented in the mclust package to estimate the most appropriate number of clusters in the simulated data. When this estimate is calculated by the mixture model, an assumption can be made about the variability of the Normal mixtures that are fitted, i.e. they can ...
... We used a mixture model algorithm implemented in the mclust package to estimate the most appropriate number of clusters in the simulated data. When this estimate is calculated by the mixture model, an assumption can be made about the variability of the Normal mixtures that are fitted, i.e. they can ...
Uncovering evolutionary patterns of gene expression using
... the level of the sequence of the regulatory elements and at the level of transcript abundance. There is currently solid evidence that natural selection has a major role in the dynamics of change of transcript abundance. By contrast, and although there is some evidence that natural selection also has ...
... the level of the sequence of the regulatory elements and at the level of transcript abundance. There is currently solid evidence that natural selection has a major role in the dynamics of change of transcript abundance. By contrast, and although there is some evidence that natural selection also has ...
Performance Comparison of Two Gene Set Analysis Methods for
... smaller. As shown in Fig. 2, the imputation increased the significance of many genes. This has the effect of reducing the number of hits for the GSA-SNP runs with the imputed dataset compared with the unimputed one, similar to the argument given above for the schemes of assigning the best or second- ...
... smaller. As shown in Fig. 2, the imputation increased the significance of many genes. This has the effect of reducing the number of hits for the GSA-SNP runs with the imputed dataset compared with the unimputed one, similar to the argument given above for the schemes of assigning the best or second- ...
Epigenetic chromatin states uniquely define the developmental
... lose self-renewal ability and develop through a series of specialized progenitor cell types that possess restricted differentiation potential.1 Although several cell-intrinsic and microenvironmental factors that can control these processes have been identified, the precise molecular circuitry contro ...
... lose self-renewal ability and develop through a series of specialized progenitor cell types that possess restricted differentiation potential.1 Although several cell-intrinsic and microenvironmental factors that can control these processes have been identified, the precise molecular circuitry contro ...
Identification of the equine herpesvirus type 1 glycoprotein 17/18 as
... gD was confirmed by sequence analysis of the DNA upstream of the gI and gE genes (Audonnet et al., 1990; Elton et al., 1991 b). The complete nucleotide sequence of the EHV-1 strain Abl gD homologue was obtained from both strands of the D N A by sequencing a 1602 bp Sinai to HindlII region from the U ...
... gD was confirmed by sequence analysis of the DNA upstream of the gI and gE genes (Audonnet et al., 1990; Elton et al., 1991 b). The complete nucleotide sequence of the EHV-1 strain Abl gD homologue was obtained from both strands of the D N A by sequencing a 1602 bp Sinai to HindlII region from the U ...
Text S1.
... lose their Preyer reflex by about 1-2 months of age, this test was not a useful discriminator for these mice. Compound heterozygote offspring (dfw/Obl) showed vestibular phenotypes, intermediate between those seen in the two parental (homozygous) mutants, suggesting that they did not complement and ...
... lose their Preyer reflex by about 1-2 months of age, this test was not a useful discriminator for these mice. Compound heterozygote offspring (dfw/Obl) showed vestibular phenotypes, intermediate between those seen in the two parental (homozygous) mutants, suggesting that they did not complement and ...
Sex-linked dosage-sensitive modifiers as imprinting
... (Locke et al. 1988), as well as modifiers of other phenotypes in Drosophila (Rabinow and Birchler, 1989), are responsive to gene dosage. Locke et al. (1988) have described a number of modifying genes that affect white-mottled and yellow variegation. Their extensive genetic analyses define two classe ...
... (Locke et al. 1988), as well as modifiers of other phenotypes in Drosophila (Rabinow and Birchler, 1989), are responsive to gene dosage. Locke et al. (1988) have described a number of modifying genes that affect white-mottled and yellow variegation. Their extensive genetic analyses define two classe ...
File
... Scientific Skills Exercise The diagrams on the next slide show an intact DNA sequence (top) and three experimental DNA sequences. A red X indicates the possible control element (1, 2, or 3) that was deleted in each experimental DNA sequence. The area between the slashes represents the approximately ...
... Scientific Skills Exercise The diagrams on the next slide show an intact DNA sequence (top) and three experimental DNA sequences. A red X indicates the possible control element (1, 2, or 3) that was deleted in each experimental DNA sequence. The area between the slashes represents the approximately ...
Warren, ST: Trinucleotide repetition and fragile X syndrome. Hospital Practice 32:73 - 98 (1997). cover illustration.
... such as TCCAATGGCGCT... (to cite at random some code from exon 1 of FMR1), a mistake arising from polymerase slippage along the template will be rapidly caught when the polymerase tries to impose an incorrect base pairing. (To form the DNA double helix, A links with T and G links with C.) If, on the ...
... such as TCCAATGGCGCT... (to cite at random some code from exon 1 of FMR1), a mistake arising from polymerase slippage along the template will be rapidly caught when the polymerase tries to impose an incorrect base pairing. (To form the DNA double helix, A links with T and G links with C.) If, on the ...
A Separate Peace – Pre
... would have lost face with Phineas, and that would have been unthinkable.” What does this tell us about Gene’s attitude towards Phineas? How important is Phineas to Gene’s self-identity? (What role does Phineas play in Gene’s perception of himself?) While you read: Pay attention to Finny’s pers ...
... would have lost face with Phineas, and that would have been unthinkable.” What does this tell us about Gene’s attitude towards Phineas? How important is Phineas to Gene’s self-identity? (What role does Phineas play in Gene’s perception of himself?) While you read: Pay attention to Finny’s pers ...
the molecular similarity between Mowat-Wilson syndrome
... voltage-gated ion channels27. To circumvent embryonic lethality and/or underscore the role for ZEB2 in detail, homozygous deletion of Zeb2 has been conducted through the Cre-loxP system under organ-specific promoters. Neural crest-specific Zeb2 knockout mice display craniofacial and gastrointestinal ...
... voltage-gated ion channels27. To circumvent embryonic lethality and/or underscore the role for ZEB2 in detail, homozygous deletion of Zeb2 has been conducted through the Cre-loxP system under organ-specific promoters. Neural crest-specific Zeb2 knockout mice display craniofacial and gastrointestinal ...