Restriction Fragment Length Polymorphism of hsp70
... Previous studies from our laboratory have demonstrated that the intermediate phenotype of thermosensitivity is present in hypertensive mice and rats. Increased expression of hsp70 caused by increased transcription rate was demonstrated in vivo, in organs, and in cultured cells from spontaneously hyp ...
... Previous studies from our laboratory have demonstrated that the intermediate phenotype of thermosensitivity is present in hypertensive mice and rats. Increased expression of hsp70 caused by increased transcription rate was demonstrated in vivo, in organs, and in cultured cells from spontaneously hyp ...
Xiong, N., C.H. Kang, and D.H. Raulet. 2002. Redundant and unique roles of two enhancer elements in the TCR gamma locus in gene regulation and gamma delta T cell development. Immunity 16:453-463.
... neo cassette flanked by loxP sites in J1 ES cells (Figures 1E and 1F). Chimeric mice were generated and crossed to a CD1 strain that expresses a CMV-Cre transgene that directs Cre synthesis in germ cells, resulting in deletion of the neo cassette in vivo. The E⫹/⫺ mice were crossed back to B6 mice, ...
... neo cassette flanked by loxP sites in J1 ES cells (Figures 1E and 1F). Chimeric mice were generated and crossed to a CD1 strain that expresses a CMV-Cre transgene that directs Cre synthesis in germ cells, resulting in deletion of the neo cassette in vivo. The E⫹/⫺ mice were crossed back to B6 mice, ...
Youngson and Whitelaw, 2008
... inheritance, parental effects, and fetal programming, among others. Although in many instances these phrases refer to different phenomena, including both physiological and behavioral (intellectual) processes, they all involve a transfer of nongenetic information across generations; i.e., they are tr ...
... inheritance, parental effects, and fetal programming, among others. Although in many instances these phrases refer to different phenomena, including both physiological and behavioral (intellectual) processes, they all involve a transfer of nongenetic information across generations; i.e., they are tr ...
Localization of Three Genes in the Hook
... Electron micrograph studies of hamster spermatozoa revealed that fully condensed hamster sperm nuclei have a characteristic, asymmetrical hook-shaped nucleus that is very flat [27]. Yanagimachi and Noda [27] determined that the nucleus is only 0.5-0.6 gm at its thickest point and 0.20.25 m at the th ...
... Electron micrograph studies of hamster spermatozoa revealed that fully condensed hamster sperm nuclei have a characteristic, asymmetrical hook-shaped nucleus that is very flat [27]. Yanagimachi and Noda [27] determined that the nucleus is only 0.5-0.6 gm at its thickest point and 0.20.25 m at the th ...
Polygenic inheritance and micro/minisatellites
... Figure 1 Illustrative examples of the association between alleles of repeat polymorphisms at a variety of genes and quantitative behavioral traits. (a) Monoamine oxidase A gene (MAOA) and VNTR polymorphism alleles divided into four groups. There was a significant association with a number of quantit ...
... Figure 1 Illustrative examples of the association between alleles of repeat polymorphisms at a variety of genes and quantitative behavioral traits. (a) Monoamine oxidase A gene (MAOA) and VNTR polymorphism alleles divided into four groups. There was a significant association with a number of quantit ...
Regulation and Flexibility of Genomic Imprinting
... and maize (Zea mays) have shown a strong correlation between silent or active states with epigenetic marks, such as DNA methylation and histone modifications, but the nature of the primary imprint has not been clearly established for all imprinted genes. Phenotypes and expression patterns of imprint ...
... and maize (Zea mays) have shown a strong correlation between silent or active states with epigenetic marks, such as DNA methylation and histone modifications, but the nature of the primary imprint has not been clearly established for all imprinted genes. Phenotypes and expression patterns of imprint ...
The regulation of expression of the porin gene ompC
... The regulation of expression of the porin genes of Escherichiu cofiby acid pH was investigated using reporter gene fusions. The ompC-ZacZ gene fusion was expressed in response to acidification of the external medium. The kinetics of P-galactosidase synthesis under acid-induction differed significant ...
... The regulation of expression of the porin genes of Escherichiu cofiby acid pH was investigated using reporter gene fusions. The ompC-ZacZ gene fusion was expressed in response to acidification of the external medium. The kinetics of P-galactosidase synthesis under acid-induction differed significant ...
X chromosome gene expression in human tissues
... particular, for the 27 X-linked genes previously reported by Carrel and Willard [2] to escape inactivation (i.e., using the somatic cell hybrid system), Nguyen and Disteche [16] found a significant increase in expression in females for only a few of these escaped genes. Because of a paucity of femal ...
... particular, for the 27 X-linked genes previously reported by Carrel and Willard [2] to escape inactivation (i.e., using the somatic cell hybrid system), Nguyen and Disteche [16] found a significant increase in expression in females for only a few of these escaped genes. Because of a paucity of femal ...
The case of KC: contributions of a memory
... single-locus model of amnesia. Today, there are as many puzzles surrounding memory impairment as there are surrounding “normal” memory. For instance, it is becoming increasingly clear that there is more than one type of declarative memory impairment much as there is more than one type of declarative ...
... single-locus model of amnesia. Today, there are as many puzzles surrounding memory impairment as there are surrounding “normal” memory. For instance, it is becoming increasingly clear that there is more than one type of declarative memory impairment much as there is more than one type of declarative ...
Changes in DNA-binding activity of transcription factors in the
... DNA-protein complexes strongly decreased. Specificity of Sp1 DNA-protein complexes was confirmed by competition experiments (Photo 5B). In the last several years the transcription factors were extensively studied in the mammary glands of mice and rats, and certain transcription factors involved in t ...
... DNA-protein complexes strongly decreased. Specificity of Sp1 DNA-protein complexes was confirmed by competition experiments (Photo 5B). In the last several years the transcription factors were extensively studied in the mammary glands of mice and rats, and certain transcription factors involved in t ...
Arabidopsis Ethylene-Responsive Element Binding
... plants. Genome projects are providing a wealth of information about sequences encoding ERF proteins in Arabidopsis, but information regarding physiological function and gene regulation of this family of transcription factors is still lacking. In this report, we isolated cDNAs encoding Arabidopsis ER ...
... plants. Genome projects are providing a wealth of information about sequences encoding ERF proteins in Arabidopsis, but information regarding physiological function and gene regulation of this family of transcription factors is still lacking. In this report, we isolated cDNAs encoding Arabidopsis ER ...
Supplementary Figure Legends - Word file
... promoter activation. A simplistic display of a P.falciparum nucleus divided into the transcriptionally incompetent nuclear periphery (red) and a transcriptionally active central region (green) that extends to the nuclear membrane at one site. This previously described active perinuclear zone1 includ ...
... promoter activation. A simplistic display of a P.falciparum nucleus divided into the transcriptionally incompetent nuclear periphery (red) and a transcriptionally active central region (green) that extends to the nuclear membrane at one site. This previously described active perinuclear zone1 includ ...
Chapter 8
... Pre-mRNAs and other nuclear RNAs are collectively known as heterogeneous nuclear RNA (hnRNA). hnRNA is extensively bound to binding proteins, and complexes between hnRNA and protein are called heterogeneous ribonucleoprotein particles (hnRNP). Binding proteins function by preventing hnRNA from formi ...
... Pre-mRNAs and other nuclear RNAs are collectively known as heterogeneous nuclear RNA (hnRNA). hnRNA is extensively bound to binding proteins, and complexes between hnRNA and protein are called heterogeneous ribonucleoprotein particles (hnRNP). Binding proteins function by preventing hnRNA from formi ...
is involved in hair formation and spermatogenesis in mice gene
... mouse Ovo share 73% identity with equivalent segments of Drosophila Ovo/Svb (Garfinkel et al. 1994) and 94% identity with human Ovo1 (hOvo1; Chidambaram et al. 1997). On the basis of this similarity, we will refer to our sequence as mouse Ovo1a (mOvo1a). As this work was in progress, the sequence of ...
... mouse Ovo share 73% identity with equivalent segments of Drosophila Ovo/Svb (Garfinkel et al. 1994) and 94% identity with human Ovo1 (hOvo1; Chidambaram et al. 1997). On the basis of this similarity, we will refer to our sequence as mouse Ovo1a (mOvo1a). As this work was in progress, the sequence of ...
Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer
... apparent, because a change in DNA copy number does not necessarily induce actual alterations in expression (4). The issue is further complicated by the observation that many aberrations span large chromosomal regions that contain multiple genes (1), including many that are not directly related to ca ...
... apparent, because a change in DNA copy number does not necessarily induce actual alterations in expression (4). The issue is further complicated by the observation that many aberrations span large chromosomal regions that contain multiple genes (1), including many that are not directly related to ca ...
2 introduction - diss.fu
... chromosome 21 have also been repoterd (Delabar et al., 1992). Trisomies are due to the presence of three, instead of two, chromosomes of a particular numbered type in an organism. As for monosomies, trisomies can be partial. Most trisomies result in spontaneous abortion, the most common types that s ...
... chromosome 21 have also been repoterd (Delabar et al., 1992). Trisomies are due to the presence of three, instead of two, chromosomes of a particular numbered type in an organism. As for monosomies, trisomies can be partial. Most trisomies result in spontaneous abortion, the most common types that s ...
PDF - American Society of Mammalogists
... are not equivalent, and that both are needed in a 1:1 ratio for normal development. Chimeric embryo experiments suggest that this parental nonequivalence is not limited to placental versus fetal development. Cells from (marked) androgenetic and gynogenetic zygotes may be aggregated with those of nor ...
... are not equivalent, and that both are needed in a 1:1 ratio for normal development. Chimeric embryo experiments suggest that this parental nonequivalence is not limited to placental versus fetal development. Cells from (marked) androgenetic and gynogenetic zygotes may be aggregated with those of nor ...
Guidelines for BioLINK Gene List Evaluation
... large cells in the embryonic nervous system." "Dependence on the intensity of Drosophila virilis sexual behavior on age-related differences was studied. Most active proved to be those age periods which correlated with the time of S-esterase elevated activity." [S-esterase is a Drosophila virilis gen ...
... large cells in the embryonic nervous system." "Dependence on the intensity of Drosophila virilis sexual behavior on age-related differences was studied. Most active proved to be those age periods which correlated with the time of S-esterase elevated activity." [S-esterase is a Drosophila virilis gen ...
Case Report Section
... with fever, and chest infection was diagnosed with acute myeloid leukemia FAB M4 in February 2010. His biochemistry was significant for GGT (8 IU/L; normal 9-40) and LDH 350 (normal 90-225). Chromosomal studies performed at diagnosis revealed the karyotype 46,Y,t(X;11)(q22;q23) in 25 out of 30 metap ...
... with fever, and chest infection was diagnosed with acute myeloid leukemia FAB M4 in February 2010. His biochemistry was significant for GGT (8 IU/L; normal 9-40) and LDH 350 (normal 90-225). Chromosomal studies performed at diagnosis revealed the karyotype 46,Y,t(X;11)(q22;q23) in 25 out of 30 metap ...
Tobacco TTG2 regulates vegetative growth and seed production via
... NPR1, but sequesters NPR1 from the nucleus, thereby preventing NPR1 from transcriptionally regulating immune responses [4]. In another study paradigm, AtTTG1 of Arabidopsis thaliana Johannes Thal interacts with the bHLH transcription factor GL3, whereas its heterogenous binary complex further intera ...
... NPR1, but sequesters NPR1 from the nucleus, thereby preventing NPR1 from transcriptionally regulating immune responses [4]. In another study paradigm, AtTTG1 of Arabidopsis thaliana Johannes Thal interacts with the bHLH transcription factor GL3, whereas its heterogenous binary complex further intera ...
Functional analyses of genetic pathways controlling
... containing a non-core eudicot paleoAP3 motif has been shown to be sufficient to rescue stamen, but not petal, identity in Arabidopsis (Lamb and Irish, 2003). By contrast, other studies have shown that ectopic overexpression of a monocot paleoAP3 gene can rescue both petal and stamen development, sug ...
... containing a non-core eudicot paleoAP3 motif has been shown to be sufficient to rescue stamen, but not petal, identity in Arabidopsis (Lamb and Irish, 2003). By contrast, other studies have shown that ectopic overexpression of a monocot paleoAP3 gene can rescue both petal and stamen development, sug ...
Refine Query Set - University of Delaware
... Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis. RTK pathways establish cell fates in a wide range of developmental processes. However, how the pathway effector MAPK coordinately regulates the expression of multiple target genes is not fully understood. We ...
... Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis. RTK pathways establish cell fates in a wide range of developmental processes. However, how the pathway effector MAPK coordinately regulates the expression of multiple target genes is not fully understood. We ...
Hippocampal Amnesia - Institute of Cognitive Neuroscience
... hemispheric patients to suffer combined non-verbal and verbal problems than right hemispheric patients (Ott and Saver, 1993). Consistent with a dominant role for the left hippocampus in memory for personally experienced events (‘episodic memory’, see below), the majority of amnesic patients with uni ...
... hemispheric patients to suffer combined non-verbal and verbal problems than right hemispheric patients (Ott and Saver, 1993). Consistent with a dominant role for the left hippocampus in memory for personally experienced events (‘episodic memory’, see below), the majority of amnesic patients with uni ...
modification Identifying regulatory mechanisms using individual
... fraction of the variance: explaining ⬎50% PGV for 828 genes, as compared with 238 in the analysis of Brem and Kruglyak (16) of the same data set. Our comparison to three simpler Geronemo models suggests that most of the improvement results from the incorporation of trans-E regulation, which captures ...
... fraction of the variance: explaining ⬎50% PGV for 828 genes, as compared with 238 in the analysis of Brem and Kruglyak (16) of the same data set. Our comparison to three simpler Geronemo models suggests that most of the improvement results from the incorporation of trans-E regulation, which captures ...
Identifying regulatory mechanisms using individual variation reveals key role for... modification
... fraction of the variance: explaining ⬎50% PGV for 828 genes, as compared with 238 in the analysis of Brem and Kruglyak (16) of the same data set. Our comparison to three simpler Geronemo models suggests that most of the improvement results from the incorporation of trans-E regulation, which captures ...
... fraction of the variance: explaining ⬎50% PGV for 828 genes, as compared with 238 in the analysis of Brem and Kruglyak (16) of the same data set. Our comparison to three simpler Geronemo models suggests that most of the improvement results from the incorporation of trans-E regulation, which captures ...