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Memory, Learning, and Synaptic Plasticity
Memory, Learning, and Synaptic Plasticity

... retained for seconds to minutes, whereas long-term memories can last for hours to years (Figure 10–4). As we will learn later in the chapter, there are mechanistic differences between short-term and long-term memory. Third, distinct steps of the memory process and different types of memory require t ...
Cloning, characterization and in vitro and in planta expression of a
Cloning, characterization and in vitro and in planta expression of a

... b(1,6)glucan elicitors that are released during this process are perceived by the plant, by a presumed plasma membrane-bound receptor, and a signaling cascade is initiated, resulting in the up-regulation of a number of plant defenses. Since the recent identification of GIPs, studies have focused on ...
Poster - University of British Columbia
Poster - University of British Columbia

... stronger than the effect of budesonide. In current smokers, more Phase 1 enzyme genes were upregulated compared with former smokers. However, Phase 2 enzyme genes were up-regulated in former smokers but down-regulated in current smokers. Specifically, CYP1B1 was shown to have a two-fold increase in ...
Genome-wide expression analysis of cultured
Genome-wide expression analysis of cultured

... located on chromosome 21 and/or a more global transcriptional misregulation that crosses chromosomal borders. METHODS: To address this issue, four RNA samples from trisomy 21 placentas and four samples from normal first trimester pregnancies were analyzed using Affymetrix U95v2 microarray. Statistic ...
File
File

... One collecting site was in Arizona. The other three were in New Mexico. Dr. Nachman and colleagues observed no significant differences in the color of the rocks in the four locations sampled. However, the dark-colored mice from the three New Mexico locations were slightly darker than the dark-colore ...
Garcia & Koellings (1966)
Garcia & Koellings (1966)

... Rats have “Bait Shyness”: one trial learning… One taste of poison & will not eat again However will go back to the place where the poison was encountered Did the rat learn only taste-aversion? Selectively learn?…where’s contiguity? Only associated taste & odor not visual cues? ...
ARTICLE  IN  PRESS Neural Networks entorhinal cortex
ARTICLE IN PRESS Neural Networks entorhinal cortex

... pyramidal neurons in layer II of medial entorhinal cortex show persistent spiking, whereas others show spiking that self-terminates over periods of many seconds (Klink & Alonso, 1997). Pyramidal cells in layer III show stable persistent spiking that can last for two minutes or more (Yoshida et al., ...
Fc RIIIB Gene Duplication: Evidence for Presence and Expression of
Fc RIIIB Gene Duplication: Evidence for Presence and Expression of

... duplication exists. However, with these methods the possibility of one FcgRIIIB gene-deficient chromosome and two FcgRIIIB genes on the other one cannot be ruled out.14 If we assume that the SH-FcgRIIIB gene is only present in association with a second FcgRIIIB gene on the same chromosome, then the ...
3DNA Printer: A Tool for Automated DNA Origami
3DNA Printer: A Tool for Automated DNA Origami

... is an open source implemented in java while DAEDALUS is an open source implemented in MATLAB, which is not an open source even though it is free to use. We have slightly modified the algorithm used in DAEDALUS for efficiency. This software basically takes in the .obj file of any 3d shape (current ve ...
10709_2015_9875_MOESM4_ESM
10709_2015_9875_MOESM4_ESM

... A1-A3). Moreover, in the case of negative binomial regression models, dominance was not found to be correlated with the GI degree (in both positive and negative GI networks from the Costanzo study and BioGRID; see Fig. A4). We also repeated the chemogenetic analyses. The results were ambiguous. We f ...
An Arabidopsis Minute
An Arabidopsis Minute

... from a considerable number of ribosomal proteins (RPs) and ribosomal RNAs (Moore, 1998). From one of the most wellstudied models for ribosome structure and constitution, the rat, we now know that eukaryotic ribosomes consist of 82 different, highly conserved proteins (Wool et al., 1995). The importa ...
Polycomb Group silencers collaborate with Notch pathway to cause
Polycomb Group silencers collaborate with Notch pathway to cause

... Heterozygous Polycomb3 (Pc3/+) flies develop an extra sex comb on the second and third legs, as well as suffering antenna-to-leg and halter-to-wing transformations at low penetrance. These phenotypes are caused by de-repression of the silencing of Hox genes. Indeed, enhancement or suppression of the ...
PDF
PDF

... migrating to the cortex. Reduced activity is also observed in GABAergic interneurons of the adult somatosensory cortex. The SNP affects the affinity of Dlx proteins for their binding site in vitro and reduces the transcriptional activation of the enhancer by Dlx proteins. Affinity purification using ...
5` Flanking Sequences of the Rat Tyrosine Hydroxylase Gene Target
5` Flanking Sequences of the Rat Tyrosine Hydroxylase Gene Target

... express TH at different times, and are functionally and anatomically distinct (Specht et al., 198 la; Bjorklund and Lindvall, 1984). The mechanism responsible for TH expression in such disparate cell groups might be expected to rely on multiple regulatory elements, some that may be needed in all TH ...
Operon Control of Gene Expression - Glebe
Operon Control of Gene Expression - Glebe

... Operon Control of Gene Expression ...
Gene ORGANizer: linking genes to the organs they
Gene ORGANizer: linking genes to the organs they

... Many high-throughput methods such as whole-genome sequencing, expression microarrays, RNA-seq, and wholegenome methylation mapping produce genome-wide data whose analyses produce long lists of genes of interest. These lists typically include genes that share a certain trait such as being bound by th ...
Trends in Gene - silencing Research
Trends in Gene - silencing Research

... the former was dominant until 1997 while the latter became dominant after 2002. This reflects the shift of researchers’ interest into small double-stranded RNAs after the mechanism for RNA-mediated gene silencing was fundamentally understood by 2001. Furthermore, many reports suggesting the mutual i ...
Gene Section FANCD2 (Fanconi anemia, complementation group D2) Atlas of Genetics and Cytogenetics
Gene Section FANCD2 (Fanconi anemia, complementation group D2) Atlas of Genetics and Cytogenetics

... Fanconi anaemia is a chromosome instability syndrome/cancer prone disease (at risk of leukaemia and squamous cell carcinoma). Prognosis Fanconi anaemia's prognosis is poor; mean survival is 20 years: patients die of bone marrow failure (infections, haemorrhages), leukaemia, or solid cancer. It has r ...
Behavioral verification of associative learning in whisker
Behavioral verification of associative learning in whisker

... direct function of the intensity of the UCS. For example, Morris and Bouton (2006) observed that the point in conditioning training at which freezing emerged and the asymptotic amount of freezing was directly related to the intensity of the UCS (footshock). Other studies indicate that performance in ...
PDF
PDF

... the DNA sequence. The levels of ung gene expression molecular mass and contains asingle residue of cysteine which remain constant up to the early stationary phase, but is not involved in the catalytic activity of the enzyme (2). The decline in the late stationary phase of the E. coli cul- uracil DNA ...
I. Līduma, T. Tračevska, U. Bērs, A. Žileviča. Phenotypic and Genetic
I. Līduma, T. Tračevska, U. Bērs, A. Žileviča. Phenotypic and Genetic

... epidermidis is their capability to form a biofilm on the surfaces of implanted medical devices. The accumulative phase of biofilm formation is linked to the production of intercellular adhesin encoded by the icaADBC operon and accumulation-associated protein by the aap gene. The aim of the study was ...
New techniques in plant biotechnology
New techniques in plant biotechnology

... genetically modified organisms”2 a GMO is defined as: “an organism, with the exception of human beings, in which the genetic material has been altered in a way that does not occur naturally by mating and/or natural recombination”. This directive also states “according to this definition: a) genetic ...
Different Species Common Arthritis Quantitative Trait Loci in High
Different Species Common Arthritis Quantitative Trait Loci in High

... hand, identification of susceptibility genes within the QTLs is still a challenging task, with the exceptions of few genes with very strong effect on the disease, e.g., NCF1 (7). In most cases, a single quantitative trait gene contributes only mildly or moderately to the outcome of the complex trait ...
Stochastic Gene Expression:
Stochastic Gene Expression:

... fixed. A simple and possibly common way to do this is if [P] activates a process that makes further fluctuation in [P] irrelevant. P could, for instance, be a transcription factor that activates another gene with a more stable activation kinetics. Such a mechanism would require that the response to ...
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish
Two Cyp19 (P450 Aromatase) Genes on Duplicated Zebrafish

... changes of four amino acids and a premature termination resulting in the loss of eight amino acids at the Cterminus of cyp19a in the sequence of accession AF004521. The other sequence in GenBank (accession number AF120031) is a partial sequence. It differs from our cyp19b (accession number AF183908) ...
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Epigenetics in learning and memory

While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
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