A Common Polygenic Basis for Quinine and
... Inbred strains of mice (Mus musculus) differ greatly in ability to taste various bitter compounds. For some compounds, the differences result from allelic variation at a single locus. However, segregation patterns incompatible with monogenic inheritance have been found for quinine avoidance. The Soa ...
... Inbred strains of mice (Mus musculus) differ greatly in ability to taste various bitter compounds. For some compounds, the differences result from allelic variation at a single locus. However, segregation patterns incompatible with monogenic inheritance have been found for quinine avoidance. The Soa ...
Free recall and recognition in a network model of the... simulating effects of scopolamine on human memory function
... structures. (1) Acetylcholine decreases the release of the excitatory transmitter glutamate at specific synapses within the cortex [54,57,152]. Scopolamine blocks this suppression of excitatory synaptic transmission, resulting in stronger excitatory feedback. (2) Acetylcholine depolarizes cortical p ...
... structures. (1) Acetylcholine decreases the release of the excitatory transmitter glutamate at specific synapses within the cortex [54,57,152]. Scopolamine blocks this suppression of excitatory synaptic transmission, resulting in stronger excitatory feedback. (2) Acetylcholine depolarizes cortical p ...
operon
... Attenuation is fairly common • Although attenuation was once considered to be an unusual type of regulation, it is relatively common • This is especially true for operons involved in amino acid biosynthesis • In some operons, attenuation complements regulation via the operator; in others it is the ...
... Attenuation is fairly common • Although attenuation was once considered to be an unusual type of regulation, it is relatively common • This is especially true for operons involved in amino acid biosynthesis • In some operons, attenuation complements regulation via the operator; in others it is the ...
Julio`s MCB - Digital Access to Scholarship at Harvard
... morpholinos and cell sorting analysis in transgenic zebrafish embryos, we show that GATA-1 directly regulates the expression of Mfrn1. Mutagenesis of individual GATA-1 binding cis elements (GBE) demonstrated that at least two of the three GBE within this CRM are functionally required for GATA-mediat ...
... morpholinos and cell sorting analysis in transgenic zebrafish embryos, we show that GATA-1 directly regulates the expression of Mfrn1. Mutagenesis of individual GATA-1 binding cis elements (GBE) demonstrated that at least two of the three GBE within this CRM are functionally required for GATA-mediat ...
anterior olfactory nucleus (aon) - Dashboard
... The anterior olfactory nucleus (AON) is a substructure of the olfactory areas, located within the rostral portion of the cerebral cortex. The AON is comprised of dorsal (AONd), external (AONe), lateral (AONl), medial (AONm) and posteroventral (AONpv) subdivisions. Rostrally, the AONe surrounds the r ...
... The anterior olfactory nucleus (AON) is a substructure of the olfactory areas, located within the rostral portion of the cerebral cortex. The AON is comprised of dorsal (AONd), external (AONe), lateral (AONl), medial (AONm) and posteroventral (AONpv) subdivisions. Rostrally, the AONe surrounds the r ...
Host Genetic Control of Incubation Periods of Creutzfeldt
... inoculation. Incubation periods for NZW/Sea and A/JJms mice were significantly shorter than those for other strains. In contrast, the C57BL/6J, B10.A/SgSnSIc and B10.AKM/Ola mice had significantly longer incubation periods. Ranking of the incubation periods in i.p. injected mice almost totally corre ...
... inoculation. Incubation periods for NZW/Sea and A/JJms mice were significantly shorter than those for other strains. In contrast, the C57BL/6J, B10.A/SgSnSIc and B10.AKM/Ola mice had significantly longer incubation periods. Ranking of the incubation periods in i.p. injected mice almost totally corre ...
Centipede Hox genes - Development
... developmental genetics facilitates this, as it provides some basis for speculating about the developmental processes of other arthropods. The body plan of Drosophila is encoded in part by the patterned expression of a set of transcription factors called the Hox proteins, which divide the embryo into ...
... developmental genetics facilitates this, as it provides some basis for speculating about the developmental processes of other arthropods. The body plan of Drosophila is encoded in part by the patterned expression of a set of transcription factors called the Hox proteins, which divide the embryo into ...
Am I a Warrior? - Erasmus University Thesis Repository
... The gene is especially associated with social skills, empathy for others and the pleasure of being with others. Whether a person is ‘good’ in having empathy for others is very interesting for this research because the capability to have empathy is expected to have influence on the sales competences. ...
... The gene is especially associated with social skills, empathy for others and the pleasure of being with others. Whether a person is ‘good’ in having empathy for others is very interesting for this research because the capability to have empathy is expected to have influence on the sales competences. ...
The impact of iconic gestures on foreign language word learning
... whether the enhancing effect on verbal memory when performing a speech gesture during word learning is caused by the physical performance of the action itself, by the reactivation of a mental image, or possibly both. We reason that if the enhancement only depends on motor activity or on multimodalit ...
... whether the enhancing effect on verbal memory when performing a speech gesture during word learning is caused by the physical performance of the action itself, by the reactivation of a mental image, or possibly both. We reason that if the enhancement only depends on motor activity or on multimodalit ...
jxb.oxfordjournals.org - Oxford Academic
... endosperm. Moreover, amylose content is one of the key factors used for evaluating rice grain quality (Fitzgerald et al., 2009; Jeon et al., 2010). However, how these genes are regulated during rice seed development remains poorly understood. The rice Wx gene encodes the OsGBSSI, a key enzyme for ...
... endosperm. Moreover, amylose content is one of the key factors used for evaluating rice grain quality (Fitzgerald et al., 2009; Jeon et al., 2010). However, how these genes are regulated during rice seed development remains poorly understood. The rice Wx gene encodes the OsGBSSI, a key enzyme for ...
Case Report Section
... revealed the presence t(11;22)(q23;q13) in all 20 metaphases and rearrangement of the MLL gene. Translocations involving the MLL/11q23 region are the most common genomic aberrations in infant ALL seen in ~80% of cases (Raimondi, 2004). Generally leukemia harboring MLL translocation is clinically agg ...
... revealed the presence t(11;22)(q23;q13) in all 20 metaphases and rearrangement of the MLL gene. Translocations involving the MLL/11q23 region are the most common genomic aberrations in infant ALL seen in ~80% of cases (Raimondi, 2004). Generally leukemia harboring MLL translocation is clinically agg ...
Day and Night
... Researchers recorded the electric signature of individual forebrain neurons firing during the two types of sleep. The firing pattern of recently captured memories are especially strong during slow-wave sleep and then decrease in force dramatically during REM. The neural plasticity genes turn on duri ...
... Researchers recorded the electric signature of individual forebrain neurons firing during the two types of sleep. The firing pattern of recently captured memories are especially strong during slow-wave sleep and then decrease in force dramatically during REM. The neural plasticity genes turn on duri ...
Natural variation in monoterpene synthesis in kiwifruit
... indicating that DXS is likely to be the key step in regulating MEP substrate flux in kiwifruit. ...
... indicating that DXS is likely to be the key step in regulating MEP substrate flux in kiwifruit. ...
Role of base-backbone and base-base interactions
... some interesting features of other types of steps shown in our statistics, which will be explained later in this paper by the same principle as that will be applied on understanding the RY steps. The standard deviations found in the parameters at each type of YY step are generally similar to those f ...
... some interesting features of other types of steps shown in our statistics, which will be explained later in this paper by the same principle as that will be applied on understanding the RY steps. The standard deviations found in the parameters at each type of YY step are generally similar to those f ...
Mef2 gene expression marks the cardiac and skeletal muscle
... Olson, 1990; Weintraub et al., 1991). Although most skeletal muscle genes contain E-boxes in their control regions, several that are activated by the MyoD family do not. This has led to the proposal that myogenic bHLH proteins act through intermediate myogenic regulators to activate some muscle-spec ...
... Olson, 1990; Weintraub et al., 1991). Although most skeletal muscle genes contain E-boxes in their control regions, several that are activated by the MyoD family do not. This has led to the proposal that myogenic bHLH proteins act through intermediate myogenic regulators to activate some muscle-spec ...
DnaJ-related protein essential for placentation - Development
... in only a portion of mutant conceptuses indicating that the VCAM1/α4 integrin interaction is not the only mechanism mediating chorioallantoic fusion. FGF signaling also plays a role in placental development since a hypomorphic mutation in the FGFR2 gene causes either defects in chorioallantoic fusio ...
... in only a portion of mutant conceptuses indicating that the VCAM1/α4 integrin interaction is not the only mechanism mediating chorioallantoic fusion. FGF signaling also plays a role in placental development since a hypomorphic mutation in the FGFR2 gene causes either defects in chorioallantoic fusio ...
Author`s personal copy
... and Har. hispanica would provide considerable insights into the PHA metabolism and its regulation in the domain Archaea. If a highly efficient method for mutant construction is developed, a genome-wide analysis of gene function is possible (Hammelmann and Soppa, 2008). It would not only accelerate t ...
... and Har. hispanica would provide considerable insights into the PHA metabolism and its regulation in the domain Archaea. If a highly efficient method for mutant construction is developed, a genome-wide analysis of gene function is possible (Hammelmann and Soppa, 2008). It would not only accelerate t ...
Hippocampal mechanisms for the context-dependent retrieval of episodes 2005 Special issue
... selection of turns at the choice point. The neural model can guide correct behavior in the task, as shown here. The rat moves down the stem through multiple states (bsZ1 to bsZ2 to bsZ3), then into the right arm (bsZ4,5) where it receives reward (at bsZ5), and then follows the return path (bsZ6,7,8) ...
... selection of turns at the choice point. The neural model can guide correct behavior in the task, as shown here. The rat moves down the stem through multiple states (bsZ1 to bsZ2 to bsZ3), then into the right arm (bsZ4,5) where it receives reward (at bsZ5), and then follows the return path (bsZ6,7,8) ...
Distinct Neuropathologic Phenotypes After Disrupting the
... abnormalities and decreased pain sensitivity (11). Upregulation of inflammatory genes in the hippocampi of Clcn6deficient mice suggests that there is an immune response in these mice (11), similar to that in the NCLs, but this has not been characterized in detail. gl and Clcn7-deficient mice display di ...
... abnormalities and decreased pain sensitivity (11). Upregulation of inflammatory genes in the hippocampi of Clcn6deficient mice suggests that there is an immune response in these mice (11), similar to that in the NCLs, but this has not been characterized in detail. gl and Clcn7-deficient mice display di ...
facing page
... Wright, & Wiley, J.L., 2007; Paez-Martinez et al., 2013). However, some of these same impairments are not well elucidated. In particular, the effect of toluene on the brain structure is described only in a few studies. Furthermore, most studies concerning neurobiological, neurobehavioral and other ...
... Wright, & Wiley, J.L., 2007; Paez-Martinez et al., 2013). However, some of these same impairments are not well elucidated. In particular, the effect of toluene on the brain structure is described only in a few studies. Furthermore, most studies concerning neurobiological, neurobehavioral and other ...
Cloning and expression of the phosphotriesterase
... enzymic activity in library clones. In a previous study, an OP-degrading gene was successfully isolated from an Agrobacterium strain by mobilizing a genomic library into a related strain lacking activity (Horne et al., 2002a). A similar approach was taken here, using Pseudomonas aeruginosa BENNY, a ...
... enzymic activity in library clones. In a previous study, an OP-degrading gene was successfully isolated from an Agrobacterium strain by mobilizing a genomic library into a related strain lacking activity (Horne et al., 2002a). A similar approach was taken here, using Pseudomonas aeruginosa BENNY, a ...
Knockdown of Parhyale Ultrabithorax - IMBB
... a medial location. Also, the T2 limbs themselves were often positioned more ventrally and held against the mouth like T1 maxillipeds. In addition, some PhUbx siRNA-injected animals displayed defects in gut development. The fact that none of the appendage or gut phenotypes were seen with control siRN ...
... a medial location. Also, the T2 limbs themselves were often positioned more ventrally and held against the mouth like T1 maxillipeds. In addition, some PhUbx siRNA-injected animals displayed defects in gut development. The fact that none of the appendage or gut phenotypes were seen with control siRN ...
Author`s personal copy - Sleep, Stress, and Memory Lab
... not bound to the originating context). Third, there are “how to” memories for the various skills, procedures, and habits that we acquire through experience. Because these memories are not so easily made explicit and are usually only evident in behavior, they are referred to as procedural or implicit ...
... not bound to the originating context). Third, there are “how to” memories for the various skills, procedures, and habits that we acquire through experience. Because these memories are not so easily made explicit and are usually only evident in behavior, they are referred to as procedural or implicit ...
Microbiology
... (iii) mTnSSSgusA21. This transposon was created to contain a unique SpeI site. The 2.3 kb HindIII cassette from pKWlO6 was inserted into the pBluescript SKII( ) (Stratagene) polylinker, which contains an adjacent SpeI site, to create pKW111. This was digested with XhoI and SstI and the 2.4 kb Papkgu ...
... (iii) mTnSSSgusA21. This transposon was created to contain a unique SpeI site. The 2.3 kb HindIII cassette from pKWlO6 was inserted into the pBluescript SKII( ) (Stratagene) polylinker, which contains an adjacent SpeI site, to create pKW111. This was digested with XhoI and SstI and the 2.4 kb Papkgu ...