![Relationships Between RNA Polymerase II Activity and Spt](http://s1.studyres.com/store/data/015310701_1-a870b2cbf71b51f2a0e4f049668998ae-300x300.png)
Relationships Between RNA Polymerase II Activity and Spt
... yeast genome and many of these exhibit modulation by many factors (Martens et al. 2004, 2005; Hainer et al. 2011; Bird et al. 2006). Furthermore, widespread antisense transcription is being revealed as a mechanism for shaping gene regulation in a number of ways, including transcription over promoter ...
... yeast genome and many of these exhibit modulation by many factors (Martens et al. 2004, 2005; Hainer et al. 2011; Bird et al. 2006). Furthermore, widespread antisense transcription is being revealed as a mechanism for shaping gene regulation in a number of ways, including transcription over promoter ...
Episodic memory, amnesia, and the hippocampal–anterior thalamic
... and the medial thalamus. (As a matter of terminology the term hippocampus is used here to refer to the hippocampal fields CA1-4, the dentate gyrus, and the subicular complex. The mamillary bodies and the medial thalamus are both medial components of the diencephalon, which is composed of the thalamu ...
... and the medial thalamus. (As a matter of terminology the term hippocampus is used here to refer to the hippocampal fields CA1-4, the dentate gyrus, and the subicular complex. The mamillary bodies and the medial thalamus are both medial components of the diencephalon, which is composed of the thalamu ...
Efficiency of gene silencing in Arabidopsis
... by two independent events showing the strong reduction of function phenotype P2. First, we identified microarray elements showing differential expression (P < 0.05) in at least one of the experiments. Then, we identified elements that were down- or up-regulated in hIR and/or transitive events at an ...
... by two independent events showing the strong reduction of function phenotype P2. First, we identified microarray elements showing differential expression (P < 0.05) in at least one of the experiments. Then, we identified elements that were down- or up-regulated in hIR and/or transitive events at an ...
Overtraining Does Not Mitigate Contextual Fear Conditioning
... p , 0.0001] in the ANOVA. Not surprisingly, the level of freezing behavior varied as a function of the number of conditioning trials; this was indicated by a significant main effect of trial [F(3,12) 5 6.6; p , 0.01] and a significant interaction of trial and period [F(3,12) 5 8.2; p , 0.01]. Post h ...
... p , 0.0001] in the ANOVA. Not surprisingly, the level of freezing behavior varied as a function of the number of conditioning trials; this was indicated by a significant main effect of trial [F(3,12) 5 6.6; p , 0.01] and a significant interaction of trial and period [F(3,12) 5 8.2; p , 0.01]. Post h ...
WHITE PANICLE1, a Val-tRNA Synthetase
... mutant Arabidopsis AARS genes have been characterized. twn2 had altered expression of Val-tRNA synthetase and showed suspensor-derived polyembryony (Zhang and Somerville, 1997). edd1 inactivated a GlytRNA synthetase and was arrested in embryonic development (Uwer et al., 1998). Other AARS mutants we ...
... mutant Arabidopsis AARS genes have been characterized. twn2 had altered expression of Val-tRNA synthetase and showed suspensor-derived polyembryony (Zhang and Somerville, 1997). edd1 inactivated a GlytRNA synthetase and was arrested in embryonic development (Uwer et al., 1998). Other AARS mutants we ...
In-class assignment: Fukuda et al. (2016) paper
... 7. Xist and Tsix have antagonistic functions.Are the results in 5a consistent with this? Why or why not? Explain. The results in Fig 5a indicate that Xist and Tsix are regulated similarly by Oct4. When Oct4 is knocked out, both transcript levels drop, suggesting that Oct4 is a positive regulator of ...
... 7. Xist and Tsix have antagonistic functions.Are the results in 5a consistent with this? Why or why not? Explain. The results in Fig 5a indicate that Xist and Tsix are regulated similarly by Oct4. When Oct4 is knocked out, both transcript levels drop, suggesting that Oct4 is a positive regulator of ...
Development 130, 3567-3578. - Howard Hughes Medical Institute
... homozygous Chrd;Nog mutants (Bachiller et al., 2000) in which, in addition, anterior truncations of the neural plate were also present. In zebrafish and Xenopus, inactivation of Chrd causes an expansion of ventral mesoderm and reduction of dorsal mesoderm and neural plate (Schulte-Merker et al., 199 ...
... homozygous Chrd;Nog mutants (Bachiller et al., 2000) in which, in addition, anterior truncations of the neural plate were also present. In zebrafish and Xenopus, inactivation of Chrd causes an expansion of ventral mesoderm and reduction of dorsal mesoderm and neural plate (Schulte-Merker et al., 199 ...
Genetic Ablation of Orexin Neurons in Mice Results in Narcolepsy
... Typical hypnograms, graphic representations of sleepwaking states over time, for an orexin/ataxin-3 mouse and a wild-type littermate for the 12 hr dark period (active phase) are shown in Figure 5A. The hypnogram for the transgenic mouse is characterized by the appearance of direct transitions from w ...
... Typical hypnograms, graphic representations of sleepwaking states over time, for an orexin/ataxin-3 mouse and a wild-type littermate for the 12 hr dark period (active phase) are shown in Figure 5A. The hypnogram for the transgenic mouse is characterized by the appearance of direct transitions from w ...
Mendelian and Non-Mendelian Regulation of Gene Expression in
... expression levels of 22,242 genes that were detected in both parents and at least 90% of the IBM RILs. The mean expression levels in the RILs were similar to the mid-parent values for most genes (Figure 1B). Transgressive segregation, defined here as at least 10% of RILs exhibiting expression levels ...
... expression levels of 22,242 genes that were detected in both parents and at least 90% of the IBM RILs. The mean expression levels in the RILs were similar to the mid-parent values for most genes (Figure 1B). Transgressive segregation, defined here as at least 10% of RILs exhibiting expression levels ...
Uria_et_al_2006 _ADH paper
... frequently carried out at high temperatures. There are some benefits of operating such processes at higher temperatures including decreased viscosity, increased diffussion rates, solubility of most organic compounds, an increase in reaction rates, and reduced risk of microbial contaminations (Kristj ...
... frequently carried out at high temperatures. There are some benefits of operating such processes at higher temperatures including decreased viscosity, increased diffussion rates, solubility of most organic compounds, an increase in reaction rates, and reduced risk of microbial contaminations (Kristj ...
SPT3 interacts with TFIID to allow normal transcription in
... The TFIID-G174E m u t a n t protein behaves similarly to wild-type TFHD by several assays To attempt to determine how the sptl5-21 mutation alters TFIID function, the activity of the mutant TFIID protein encoded by sptl5-21 (hereafter referred to as TFIID-G174E) was compared with that of wild-type T ...
... The TFIID-G174E m u t a n t protein behaves similarly to wild-type TFHD by several assays To attempt to determine how the sptl5-21 mutation alters TFIID function, the activity of the mutant TFIID protein encoded by sptl5-21 (hereafter referred to as TFIID-G174E) was compared with that of wild-type T ...
Sequence requirements for function of the
... machinery, amplification represents a dramatic example of how DNA replication can be regulated in response to the developmental program. The Drosophila oocyte is surrounded by a somatically derived epithelium called the follicle cells. The follicle cells lay down protective coverings around the oocy ...
... machinery, amplification represents a dramatic example of how DNA replication can be regulated in response to the developmental program. The Drosophila oocyte is surrounded by a somatically derived epithelium called the follicle cells. The follicle cells lay down protective coverings around the oocy ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
... 3969 amino acids; 431 KDa; contains from N-term to C-term 3 AT hooks homologous to high mobility group proteins HMGA1 and HMGA2, binding to the minor grove of DNA; 2 speckled nuclear localisation signals; 2 repression domains RD1 and RD2: RD1 or CXXC: cystein methyl transferase, binds CpG rich DNA, ...
... 3969 amino acids; 431 KDa; contains from N-term to C-term 3 AT hooks homologous to high mobility group proteins HMGA1 and HMGA2, binding to the minor grove of DNA; 2 speckled nuclear localisation signals; 2 repression domains RD1 and RD2: RD1 or CXXC: cystein methyl transferase, binds CpG rich DNA, ...
DNA Sequence Changes of Mutations Altering
... attenuator stem. Finally, we show that mutations that alter the attenuator stem suppress his0 mutations. This lends support to the proposal that, these his0 mutations cause reduced levels of operon expression due to excessive attenuator stem formation. The properties of these 31 mutations provide su ...
... attenuator stem. Finally, we show that mutations that alter the attenuator stem suppress his0 mutations. This lends support to the proposal that, these his0 mutations cause reduced levels of operon expression due to excessive attenuator stem formation. The properties of these 31 mutations provide su ...
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... The tac promoted toxin gene found in pMYC436 40 (pMYC47l, pMYC485, and pMYC1l6l) is constitutive and occurs independently of the concentrations of lac (NRRL deposit no. B-l8292) was cloned as a 4.5 Kbp tose or glucose present in the cell. For example, in the BamHI to PstI fragment in the vector pTJ ...
... The tac promoted toxin gene found in pMYC436 40 (pMYC47l, pMYC485, and pMYC1l6l) is constitutive and occurs independently of the concentrations of lac (NRRL deposit no. B-l8292) was cloned as a 4.5 Kbp tose or glucose present in the cell. For example, in the BamHI to PstI fragment in the vector pTJ ...
Recruitment of 5! Hoxa genes in the allantois is
... HoxAdel/del mutants is the consequence of an exacerbated placental defect as compared with the single Hoxa13 inactivation. Consistent with this assumption, abnormal placental morphology and marked reduction of the endothelium within the labyrinth are observed in all E10.5 HoxAdel/del placentas analy ...
... HoxAdel/del mutants is the consequence of an exacerbated placental defect as compared with the single Hoxa13 inactivation. Consistent with this assumption, abnormal placental morphology and marked reduction of the endothelium within the labyrinth are observed in all E10.5 HoxAdel/del placentas analy ...
Differential Gene Expression in the Siphonophore
... workflows: SOLiD SAGE (Life Technologies), Illumina mRNASeq, and Helicos Digital Gene Expression (DGE). These workflows differ in sample preparation protocols (Figure S1), sequencing platform, and read mapping. All these differences have the potential to impact each workflow’s ability to measure dif ...
... workflows: SOLiD SAGE (Life Technologies), Illumina mRNASeq, and Helicos Digital Gene Expression (DGE). These workflows differ in sample preparation protocols (Figure S1), sequencing platform, and read mapping. All these differences have the potential to impact each workflow’s ability to measure dif ...
Visualizing expression patterns of Shh and Foxf1 genes
... expressed in various organizing centers, such as the notochord, floor plate of the neural tube and polarizing region of the limbs [7]. It is involved in dorso-ventral foregut patterning [7, 8], presumably through notochord localization. The later expression of Shh in lung buds suggests that it plays ...
... expressed in various organizing centers, such as the notochord, floor plate of the neural tube and polarizing region of the limbs [7]. It is involved in dorso-ventral foregut patterning [7, 8], presumably through notochord localization. The later expression of Shh in lung buds suggests that it plays ...
Archives of Microbiology
... signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to those from Methanosarcina spp. and were clearly separated from AnfDAnfG (Fig. 2). The close similarity of the cyanobacterial vnfDG to vnfDvnfG of Methanosarcina spp. might ...
... signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to those from Methanosarcina spp. and were clearly separated from AnfDAnfG (Fig. 2). The close similarity of the cyanobacterial vnfDG to vnfDvnfG of Methanosarcina spp. might ...
Epigenetic inheritance of acquired traits through sperm RNAs and
... pregnant female rats were exposed to vinclozolin (a pesticide), the male offspring of the exposed mothers showed a wide range of disease phenotypes, which were inherited by most of the males of the subsequent generations examined that were not directly exposed to vinclozolin. In these early studies ...
... pregnant female rats were exposed to vinclozolin (a pesticide), the male offspring of the exposed mothers showed a wide range of disease phenotypes, which were inherited by most of the males of the subsequent generations examined that were not directly exposed to vinclozolin. In these early studies ...
Tomé, S., Manley, K., Simard, J.P., Clark, G.W., Slean, M.M., Swami
... in human HD and DM1 stem cells [38]. MMR is a pathway dedicated to protecting against mutations arising from mispaired nucleotides and insertion/deletion loops [39]. There are two heterodimeric protein complexes that recognize unpaired DNAs: MutSa consists of MSH2-MSH6, and MutSb is formed by MSH2–M ...
... in human HD and DM1 stem cells [38]. MMR is a pathway dedicated to protecting against mutations arising from mispaired nucleotides and insertion/deletion loops [39]. There are two heterodimeric protein complexes that recognize unpaired DNAs: MutSa consists of MSH2-MSH6, and MutSb is formed by MSH2–M ...
Gene Section LMO2 (LIM domain only 2 (rhombotin-like 1))
... amino acids; 18 kDa; 48 % amino-acid identity with LMO1 protein. LMO2 contains two transcription activating domains (one in N-term, in a prolin-rich 19 amino acid region, one in C-term) and two LIM domains as transcription ...
... amino acids; 18 kDa; 48 % amino-acid identity with LMO1 protein. LMO2 contains two transcription activating domains (one in N-term, in a prolin-rich 19 amino acid region, one in C-term) and two LIM domains as transcription ...
Genomic Organization of Evolutionarily Correlated Genes in
... These transcription factories are discrete spatial foci formed, in eukaryotes, by an elevated concentration of TFs and their target genes. 10–12 In particular, they gather genes that can be located far from each other along DNA. 13 As demonstrated in the lac operon, the increased local concentration ...
... These transcription factories are discrete spatial foci formed, in eukaryotes, by an elevated concentration of TFs and their target genes. 10–12 In particular, they gather genes that can be located far from each other along DNA. 13 As demonstrated in the lac operon, the increased local concentration ...
A Common Polygenic Basis for Quinine and
... Inbred strains of mice (Mus musculus) differ greatly in ability to taste various bitter compounds. For some compounds, the differences result from allelic variation at a single locus. However, segregation patterns incompatible with monogenic inheritance have been found for quinine avoidance. The Soa ...
... Inbred strains of mice (Mus musculus) differ greatly in ability to taste various bitter compounds. For some compounds, the differences result from allelic variation at a single locus. However, segregation patterns incompatible with monogenic inheritance have been found for quinine avoidance. The Soa ...