Cancer Prone Disease Section Retinoblastoma Atlas of Genetics and Cytogenetics
... Description: 928 aa nuclear phosphoprotein. Localisation: Nucleus. Function: Involved in cell cycle regulation. Mutations Note: Mutations predisposing to retinoblastoma are one allele mutations; in retinoblastoma, both copies of the RB1 gene are mutated (two-step inactivation mechanism typical of tu ...
... Description: 928 aa nuclear phosphoprotein. Localisation: Nucleus. Function: Involved in cell cycle regulation. Mutations Note: Mutations predisposing to retinoblastoma are one allele mutations; in retinoblastoma, both copies of the RB1 gene are mutated (two-step inactivation mechanism typical of tu ...
Comparative analysis of the Geobacillus hemicellulose utilization locus reveals a highly
... biomass to value-added products. To date the molecular determinants for hemicellulose degradation and utilization have only been identified and partially characterized in one strain, namely Geobacillus stearothermophilus T-6, where they are clustered in a single genetic locus. Results: Using the G. ...
... biomass to value-added products. To date the molecular determinants for hemicellulose degradation and utilization have only been identified and partially characterized in one strain, namely Geobacillus stearothermophilus T-6, where they are clustered in a single genetic locus. Results: Using the G. ...
Phylogeny of elasmobranchs based on LSU and SSU ribosomal
... Framework of ÔSqualoidÕ Sharks and Related Taxa, Hokkaido University Press, Sapporo, 1992]. By contrast, a recent molecularphylogenetic study based on mitochondrial genes for 12S and 16S rRNA and tRNA valine [C.J. Douady et al., Mol. Phylogenet. Evol., 26 (2003) 215–221] supported the older view tha ...
... Framework of ÔSqualoidÕ Sharks and Related Taxa, Hokkaido University Press, Sapporo, 1992]. By contrast, a recent molecularphylogenetic study based on mitochondrial genes for 12S and 16S rRNA and tRNA valine [C.J. Douady et al., Mol. Phylogenet. Evol., 26 (2003) 215–221] supported the older view tha ...
No Slide Title
... • Use in prognosis: e.g. tumors with high S phase fraction detected by flow cytometry have poorer prognosis • Use in predicting responsiveness to a particular type of therapy: e.g. high S phase fraction and loss of p53 will make cells more suceptible to DNA damaging agents ...
... • Use in prognosis: e.g. tumors with high S phase fraction detected by flow cytometry have poorer prognosis • Use in predicting responsiveness to a particular type of therapy: e.g. high S phase fraction and loss of p53 will make cells more suceptible to DNA damaging agents ...
Compaction of Duplex Nucleic Acids upon Native
... it possible to reveal the ensuing conformational responses.8-10 But before native ESI-IMS-MS can be applied to study nucleic acids conformations from solution, it is essential to understand to what extent the different types of DNA/RNA secondary structures are preserved, or affected, by the transiti ...
... it possible to reveal the ensuing conformational responses.8-10 But before native ESI-IMS-MS can be applied to study nucleic acids conformations from solution, it is essential to understand to what extent the different types of DNA/RNA secondary structures are preserved, or affected, by the transiti ...
GENtle, a free multi-purpose molecular biology tool
... molecular biology, especially biochemistry and genetics. Once a new domain restricted to a few experts, applications of bioinformatics today have penetrated into the daily routine of every work group in the field of molecular biology. Searching in online sequence databases have become a vital tool a ...
... molecular biology, especially biochemistry and genetics. Once a new domain restricted to a few experts, applications of bioinformatics today have penetrated into the daily routine of every work group in the field of molecular biology. Searching in online sequence databases have become a vital tool a ...
Genome-Wide Identification of Allelic Expression in Hypertensive
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
Revision – Unit 1 Quiz
... • A competitive inhibitor is one which • A. attaches itself to the active site of an enzyme and blocks it • B. attaches itself to another part of the enzyme away from the active site • C. attaches itself to the substrate and prevents it joining with the enzyme ...
... • A competitive inhibitor is one which • A. attaches itself to the active site of an enzyme and blocks it • B. attaches itself to another part of the enzyme away from the active site • C. attaches itself to the substrate and prevents it joining with the enzyme ...
Ectopic overexpression of castor bean LEAFY
... Inducible expression of Arabidopsis LEC2, which was regulated by the acetaldehyde-induced Alc gene, increased the abundance of total fatty acids to as much as 6.8% of the dry weight of the leaves of tobacco plants [25]. Ectopic expression of LEC2 in the COMATOSE2 (cts2) Arabidopsis mutant reduced ca ...
... Inducible expression of Arabidopsis LEC2, which was regulated by the acetaldehyde-induced Alc gene, increased the abundance of total fatty acids to as much as 6.8% of the dry weight of the leaves of tobacco plants [25]. Ectopic expression of LEC2 in the COMATOSE2 (cts2) Arabidopsis mutant reduced ca ...
Development Duplication
... Dr. Beever reports that Developmental Duplication appears to be an inherited simple recessive genetic condition. As a simple recessive genetic condition, cattle with only one copy of the DD gene are onl ...
... Dr. Beever reports that Developmental Duplication appears to be an inherited simple recessive genetic condition. As a simple recessive genetic condition, cattle with only one copy of the DD gene are onl ...
AS Biology Contents Guide
... Guide to the cells found in the retina How rod cells and cone cells produce impulses Sorting statements about cone and rod cells ...
... Guide to the cells found in the retina How rod cells and cone cells produce impulses Sorting statements about cone and rod cells ...
Application title: Cloning genes for expression in AAV vectors for
... production of recombinant proteins in bodily fluids for use in the prevention, diagnosis and treatment of disease. Gene transfer involves the extra-chromosomal expression of a gene expression construct that doesn’t interfere with the integrity of the host genome. rAAV can also be specifically design ...
... production of recombinant proteins in bodily fluids for use in the prevention, diagnosis and treatment of disease. Gene transfer involves the extra-chromosomal expression of a gene expression construct that doesn’t interfere with the integrity of the host genome. rAAV can also be specifically design ...
Genome-Wide Identification of Allelic Expression in Hypertensive Rats
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
Saccharomyces cerevisiae Contains Four Fatty Acid Activation
... Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Missouri 63110; and *Department of Biochemistry, School of Public Health, Johns Hopkins University,Baltimore, Maryland 21205 ...
... Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Missouri 63110; and *Department of Biochemistry, School of Public Health, Johns Hopkins University,Baltimore, Maryland 21205 ...
Natural variation in nucleolar dominance reveals
... opportunity to study the same NORs in an active or silenced state, an opportunity we exploited to deduce the relationships between NOR chromatin topology, transcriptional activity, and NOR localization relative to the nucleolus. We show that partial, but not complete, NOR decondensation is the cytog ...
... opportunity to study the same NORs in an active or silenced state, an opportunity we exploited to deduce the relationships between NOR chromatin topology, transcriptional activity, and NOR localization relative to the nucleolus. We show that partial, but not complete, NOR decondensation is the cytog ...
Книжечка
... this with simple microscopes, which magnified images of cells by bending light through a glass lens. To understand how such a single-lens microscope is able to magnify an image, examine Figure 2. The size of the image that falls on the picture screen of detector cells lining the back of your eye dep ...
... this with simple microscopes, which magnified images of cells by bending light through a glass lens. To understand how such a single-lens microscope is able to magnify an image, examine Figure 2. The size of the image that falls on the picture screen of detector cells lining the back of your eye dep ...
ThermalAce™ DNA Polymerase
... the ThermalAce™ enzyme by commercial entities for purposes other than research requires the user to obtain a commercial license as detailed below. The ThermalAce™ enzyme is for research use only and may not be used in clinical diagnostics without a separate license. Life Technologies Corporation ("L ...
... the ThermalAce™ enzyme by commercial entities for purposes other than research requires the user to obtain a commercial license as detailed below. The ThermalAce™ enzyme is for research use only and may not be used in clinical diagnostics without a separate license. Life Technologies Corporation ("L ...
pdf
... The site of cleavage is indicated by the short vertical arrows above the lines denoting RNA, and they are labeled with the name of the enzyme cutting at that site. The enzymes catalyzing each reaction are listed above or adjacent to the reaction arrows. b. The catalytic activity of RNase P is in the ...
... The site of cleavage is indicated by the short vertical arrows above the lines denoting RNA, and they are labeled with the name of the enzyme cutting at that site. The enzymes catalyzing each reaction are listed above or adjacent to the reaction arrows. b. The catalytic activity of RNase P is in the ...
A genome-wide analysis of DNA methylation in buccal - VU-DARE
... been identified, although for most of these variants the biological mechanisms remain to be elucidated 1. Interestingly, the majority of disease-associated genetic variation is located in regulatory regions of the genome 2, including transcription-factor-occupied regions and DNase I hypersensitive s ...
... been identified, although for most of these variants the biological mechanisms remain to be elucidated 1. Interestingly, the majority of disease-associated genetic variation is located in regulatory regions of the genome 2, including transcription-factor-occupied regions and DNase I hypersensitive s ...
The human Y chromosome: a sole survivor Noordam, MJ - UvA-DARE
... abnormalities that affect spermatogenesis and as a result, male fertility. In 1976, large deletions of the long arm of the Y chromosome (Yq) were first identified, in 1996 followed by the report of three nonoverlapping regions that could be deleted in men with spermatogenic failure and that were ter ...
... abnormalities that affect spermatogenesis and as a result, male fertility. In 1976, large deletions of the long arm of the Y chromosome (Yq) were first identified, in 1996 followed by the report of three nonoverlapping regions that could be deleted in men with spermatogenic failure and that were ter ...
The hair follicle and its stem cells as drug delivery targets
... markedly increased the transfection efficiency. These results demonstrated that genes can be selectively targeted by liposomes to the most important cells of the hair follicle. So far, this is the most selective targeting of a gene observed in vivo [24]. Future studies will include restoring hair pi ...
... markedly increased the transfection efficiency. These results demonstrated that genes can be selectively targeted by liposomes to the most important cells of the hair follicle. So far, this is the most selective targeting of a gene observed in vivo [24]. Future studies will include restoring hair pi ...
A Comparison of Dominance Mechanisms and Simple Mutation on
... optimum, (i.e. > 0:9), then we nd that Haploid-Recover outperforms ExtendedAdditive, with success rates of 35% and 15% respectively. Both methods show a rapid response to the change in environment, where the GA rapidly improves the quality of the new, poorly t, solutions that are produced as a res ...
... optimum, (i.e. > 0:9), then we nd that Haploid-Recover outperforms ExtendedAdditive, with success rates of 35% and 15% respectively. Both methods show a rapid response to the change in environment, where the GA rapidly improves the quality of the new, poorly t, solutions that are produced as a res ...
Getting a Transcription Factor to Only One Nucleus Following Mitosis
... both Swi5 and Ace2, allowing the NLS to be recognized and nuclear entry and accumulation to occur [9]. In addition to their similarities in cell cycle regulation, the Ace2 and Swi5 proteins have several regions of amino acid similarity, including a 95% similar DNA binding domain. Ace2 and Swi5 recog ...
... both Swi5 and Ace2, allowing the NLS to be recognized and nuclear entry and accumulation to occur [9]. In addition to their similarities in cell cycle regulation, the Ace2 and Swi5 proteins have several regions of amino acid similarity, including a 95% similar DNA binding domain. Ace2 and Swi5 recog ...