PPT - UCLA Health
... regions (e.g., promoter region, splice sites, and termination and polyadenylation signals) of the gene also can result in abnormal proteins or reduced levels of normal proteins. ...
... regions (e.g., promoter region, splice sites, and termination and polyadenylation signals) of the gene also can result in abnormal proteins or reduced levels of normal proteins. ...
Nucleic Acids Research, 32: D489-D492 (2004).
... Alu-associated information. The Alu elements are annotated with respect to coding region and exon/ intron location. This design facilitates queries on Alu sequences, locations, as well as motifs and compositional properties via a one-stop search page. INTRODUCTION Alu sequences are short intersperse ...
... Alu-associated information. The Alu elements are annotated with respect to coding region and exon/ intron location. This design facilitates queries on Alu sequences, locations, as well as motifs and compositional properties via a one-stop search page. INTRODUCTION Alu sequences are short intersperse ...
Getting a Transcription Factor to Only One Nucleus Following Mitosis
... both Swi5 and Ace2, allowing the NLS to be recognized and nuclear entry and accumulation to occur [9]. In addition to their similarities in cell cycle regulation, the Ace2 and Swi5 proteins have several regions of amino acid similarity, including a 95% similar DNA binding domain. Ace2 and Swi5 recog ...
... both Swi5 and Ace2, allowing the NLS to be recognized and nuclear entry and accumulation to occur [9]. In addition to their similarities in cell cycle regulation, the Ace2 and Swi5 proteins have several regions of amino acid similarity, including a 95% similar DNA binding domain. Ace2 and Swi5 recog ...
Gene Section KLK4 (kallikrein-related peptidase 4) Atlas of Genetics and Cytogenetics
... To date, the major biological function of KLK4 has been derived from porcine studies which have shown that KLK4 is important in dental enamel mineralisation by degrading amelogenin, the major protein in the enamel matrix of developing teeth. More recently, KLK4 was also reported to degrade porcine e ...
... To date, the major biological function of KLK4 has been derived from porcine studies which have shown that KLK4 is important in dental enamel mineralisation by degrading amelogenin, the major protein in the enamel matrix of developing teeth. More recently, KLK4 was also reported to degrade porcine e ...
FEMS Microbiology Letters
... were characterised from A. variabilis and Anabaena 7119, respectively. Now an 1.1 kb nifJ probe, containing part of the earlier characterised 267 bp segment, was generated by inverse PCR from Anabaena 7119 and used in hybridisation experiments of EcoRV/HindIII-digested genomic DNA from A. variabilis ...
... were characterised from A. variabilis and Anabaena 7119, respectively. Now an 1.1 kb nifJ probe, containing part of the earlier characterised 267 bp segment, was generated by inverse PCR from Anabaena 7119 and used in hybridisation experiments of EcoRV/HindIII-digested genomic DNA from A. variabilis ...
The Stress Responses of Probiotic Lactobacilli and a
... Escherichia, Enterococcus, Bacillus, and even Saccharomyces are also used as probiotics when supplemented with proved efficacy through clinical studies (Reid et al., 2003). ...
... Escherichia, Enterococcus, Bacillus, and even Saccharomyces are also used as probiotics when supplemented with proved efficacy through clinical studies (Reid et al., 2003). ...
Genetic Regulation of Meristem Maintenance and Organ
... severe mutations of DL show homeotic conversion of carpels into stamens (Fig. 3B). In weak and intermediate alleles, carpel identities are partially disturbed and may result in production of multiple carpels and/or undifferentiated cell clumps. Analysis of the DL gene shows that it encodes a protein ...
... severe mutations of DL show homeotic conversion of carpels into stamens (Fig. 3B). In weak and intermediate alleles, carpel identities are partially disturbed and may result in production of multiple carpels and/or undifferentiated cell clumps. Analysis of the DL gene shows that it encodes a protein ...
Biochemical but not clinical vitamin A deficiency results from
... FIGURE 1. DNA sequencing of exon 3 of the gene encoding transthyretin (TTR) in a control individual, 2 siblings with severe biochemical vitamin A deficiency but only mild clinical symptoms, and the siblings’ healthy mother. No irregularities in the nucleotide sequence of exon 3 of the TTR gene were ...
... FIGURE 1. DNA sequencing of exon 3 of the gene encoding transthyretin (TTR) in a control individual, 2 siblings with severe biochemical vitamin A deficiency but only mild clinical symptoms, and the siblings’ healthy mother. No irregularities in the nucleotide sequence of exon 3 of the TTR gene were ...
Identical mutations in RAG1 or RAG2 genes leading
... The RAG1 and RAG2 genes were analyzed by genomic sequencing in a series of 9 patients with typical characteristics of OS including a high number of T lymphocytes (1500-22 400/L) bearing HLA-DR activation marker, an almost complete absence of circulating B cells, a hypereosinophilia in 7 of 9 cases ...
... The RAG1 and RAG2 genes were analyzed by genomic sequencing in a series of 9 patients with typical characteristics of OS including a high number of T lymphocytes (1500-22 400/L) bearing HLA-DR activation marker, an almost complete absence of circulating B cells, a hypereosinophilia in 7 of 9 cases ...
Computer-based analyses of the protein constituents
... with a sliding window of 20 residues except for the analyses conducted for the OMA family where a sliding window of 7 residues was used. Similarly, a sliding window of 7 residues for the OMA family and of 20 residues for all other families was used to generate the mean similarity plots. Most of thes ...
... with a sliding window of 20 residues except for the analyses conducted for the OMA family where a sliding window of 7 residues was used. Similarly, a sliding window of 7 residues for the OMA family and of 20 residues for all other families was used to generate the mean similarity plots. Most of thes ...
Articles - American Scientist
... as well as showing how the discussion is being remodeled by new findings about giant viruses. Citations for the entire exchange are given on the next page. Acting as a sort of moderator, Jesús Navas-Castillo opened the tourney with an appeal to clearheadedness. “Linking vague philosophical definitio ...
... as well as showing how the discussion is being remodeled by new findings about giant viruses. Citations for the entire exchange are given on the next page. Acting as a sort of moderator, Jesús Navas-Castillo opened the tourney with an appeal to clearheadedness. “Linking vague philosophical definitio ...
cbb752-mg-spr10-bioinfo-intro
... molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with ...
... molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with ...
Phylogenetic analysis of the insect order Odonata using 28S and
... at a nucleotide position, which leads to convergence. In addition, the substitution rate for transitions (A-G or T-C) is considerably faster than that for transversions (Brown et al. 1982). These facts suggest that transitional changes in variable regions are saturated considerably faster than subst ...
... at a nucleotide position, which leads to convergence. In addition, the substitution rate for transitions (A-G or T-C) is considerably faster than that for transversions (Brown et al. 1982). These facts suggest that transitional changes in variable regions are saturated considerably faster than subst ...
Molecular Plant-Microbio Interactions
... Tn5lacZ, a lambda FIX II genomic library of strain WCS365 was screened. The DNA probe used for this screening was obtained with the chromosomal DNA insert of pMP5252 as a template for a polymerase chain reaction (PCR) with primers oMP508 and oMP509. The resulting PCR fragment consisted of 0.47 kb of ...
... Tn5lacZ, a lambda FIX II genomic library of strain WCS365 was screened. The DNA probe used for this screening was obtained with the chromosomal DNA insert of pMP5252 as a template for a polymerase chain reaction (PCR) with primers oMP508 and oMP509. The resulting PCR fragment consisted of 0.47 kb of ...
- University of Bath Opus
... similarity in sex-biased gene expression among neighbouring genes. Whether this clustering of genes with similar expression profiles is functional or instead the result of transcriptional interference with adjacent genes displaying non-functional but significant similarity in patterns of gene expres ...
... similarity in sex-biased gene expression among neighbouring genes. Whether this clustering of genes with similar expression profiles is functional or instead the result of transcriptional interference with adjacent genes displaying non-functional but significant similarity in patterns of gene expres ...
Heuris`c)search:)FastA)and)BLAST)
... sequences already available in databases. Because of the algorithm's efficiency on many microcomputers, sensitive protein database searches may now become a routine procedure for molecular biologists. The method efficiently identifies regions of similar sequence and then scores the aligned identical ...
... sequences already available in databases. Because of the algorithm's efficiency on many microcomputers, sensitive protein database searches may now become a routine procedure for molecular biologists. The method efficiently identifies regions of similar sequence and then scores the aligned identical ...
Transcript - Howard Hughes Medical Institute
... So you've seen some of the features of Rett syndrome and many of the girls go through that and develop most of these features, in fact. Rett syndrome affects about one in 10,000 girls girls that have all these features you've seen in the film and in the majority of these cases the disease is sporadi ...
... So you've seen some of the features of Rett syndrome and many of the girls go through that and develop most of these features, in fact. Rett syndrome affects about one in 10,000 girls girls that have all these features you've seen in the film and in the majority of these cases the disease is sporadi ...
WNT Signaling
... • Congenital and bilateral • Target cell membrane proteins • Mutations in both Fz4 and LRP – Frizzled mutated in seventh transmembrane domain – LRP proteins prematurely terminated – Loss of Fz4/LRP signaling ...
... • Congenital and bilateral • Target cell membrane proteins • Mutations in both Fz4 and LRP – Frizzled mutated in seventh transmembrane domain – LRP proteins prematurely terminated – Loss of Fz4/LRP signaling ...
PDF
... observation raised the possibility that the loss of asymmetric fate markers, such as lim-6::gfp, might not be a reflection of a laterality defect in which left fate has converted to the right fate, but might rather be reflective of an overall differentiation defect of ASE. To assess this possibility ...
... observation raised the possibility that the loss of asymmetric fate markers, such as lim-6::gfp, might not be a reflection of a laterality defect in which left fate has converted to the right fate, but might rather be reflective of an overall differentiation defect of ASE. To assess this possibility ...
Molecular Biology and Applied Genetics
... health institutions. It can also be used in teaching any introductory course on medical Applied Genetics and Molecular Biology and as a reference material. This lecture note is specifically designed for medical laboratory technologists, and includes only those areas of molecular cell biology and App ...
... health institutions. It can also be used in teaching any introductory course on medical Applied Genetics and Molecular Biology and as a reference material. This lecture note is specifically designed for medical laboratory technologists, and includes only those areas of molecular cell biology and App ...
docx
... for an interrogating base position includes five probes: one probe to hybridise to the WT, three probes to detect three possible single base-pair mutations, and one probe to detect single deletion. There are at least 24 probe sets for each nucleotide position, including both sense and anti-sense pro ...
... for an interrogating base position includes five probes: one probe to hybridise to the WT, three probes to detect three possible single base-pair mutations, and one probe to detect single deletion. There are at least 24 probe sets for each nucleotide position, including both sense and anti-sense pro ...
Prothrombin Gene Mutation - Hamilton Health Sciences
... It causes the body to make too much prothrombin, which makes the blood more likely to clot. Blood clots in your lungs or the deep veins of your legs can be dangerous. ...
... It causes the body to make too much prothrombin, which makes the blood more likely to clot. Blood clots in your lungs or the deep veins of your legs can be dangerous. ...
Category 2000
... with many functions, but is primarily involved in fat and energy metabolism. Therefore, it is a very interesting candidate gene for meat quality, which is one of the most important criteria in pig selection today. PPARGC1A however, does not have the same function in every tissue and there is still m ...
... with many functions, but is primarily involved in fat and energy metabolism. Therefore, it is a very interesting candidate gene for meat quality, which is one of the most important criteria in pig selection today. PPARGC1A however, does not have the same function in every tissue and there is still m ...
1 Genetic constitution of a population
... location. Other length variation is caused by variation in numbers of tandemly repeated DNA sequences at `minisatellite' or `microsatellite' loci. The former, also called VNTR (for variable number of tandem repeat) loci, consist of repeating units 10-60 base pairs long. Microsatellite (or simple seq ...
... location. Other length variation is caused by variation in numbers of tandemly repeated DNA sequences at `minisatellite' or `microsatellite' loci. The former, also called VNTR (for variable number of tandem repeat) loci, consist of repeating units 10-60 base pairs long. Microsatellite (or simple seq ...
Prep1.1 has essential genetic functions in hindbrain development
... form a subgroup of Meinox proteins that share ~80% overall amino acid sequence identity. By contrast, the Meis and Prep proteins share high amino acid sequence conservation only in specific domains (Fognani et al., 2002). An additional difference between Prep and Meis might lie in Hox proteins bindi ...
... form a subgroup of Meinox proteins that share ~80% overall amino acid sequence identity. By contrast, the Meis and Prep proteins share high amino acid sequence conservation only in specific domains (Fognani et al., 2002). An additional difference between Prep and Meis might lie in Hox proteins bindi ...