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MEF2 activity during embryogenesis - Development
MEF2 activity during embryogenesis - Development

... for the MEF2 family in neuronal differentiation. The cell type distribution of MEF2 activity has been controversial. Some studies have reported that MEF2 DNAbinding activity is restricted to muscle cells (Gossett et al., 1989; Cserjesi et al., 1991; Yu et al., 1992; Breitbart et al., 1993), whereas ...
A mixed group ll/group III twintron in the Euglena
A mixed group ll/group III twintron in the Euglena

... code for structural or functional domains. Introns represent primitive elements for mediating recombination events that assemble domains of proteins. This process is termed 'exon shuffling' (1, 2). An alternative view is that introns have been added to ancestral genes (3, 4, 5). Consequently, intron ...
CBSE XII BIO QS with key(2009-2015)
CBSE XII BIO QS with key(2009-2015)

... a) Trace the development of megaspore mother cell up to the formation of a mature embryo-sac in flowering plant b) draw a labeled diagram of the structure of mature dicot embryo ans:MMCmegaspore mother cell undergoes meiosis to form four megaspores,one of the megaspore is functional while other thre ...
Eds., N. Hamamura, S. Suzuki, S. Mendo, C. M. Barroso,... © by TERRAPUB, 2010.
Eds., N. Hamamura, S. Suzuki, S. Mendo, C. M. Barroso,... © by TERRAPUB, 2010.

... problem of concern. Environmental microbes have developed some resistance mechanisms that include mercury detoxification process, therefore these mercury resistant bacteria play important roles not only in pollution issue but in the geochemical cycle of mercury in the environment. The most-studied r ...
Oncogenic potential of the DNA replication licensing protein
Oncogenic potential of the DNA replication licensing protein

... tumor suppressor genes (Jonkers and Berns, 1996; Nusse and Varmus, 1982; Ben-David et al., 1991; Morishita et al., 1988). In this study, we investigated whether CDT1 can function as an oncogene. We demonstrate that CDT1 is highly expressed in human tumor cell lines. We also show that NIH3T3 cells ov ...
View PDF - Genetics
View PDF - Genetics

... substitution rates (albeit much less pronounced) as well as the accumulation of large indels in these species. In contrast, there was little or no evidence of accelerated sequence evolution in photosynthetic genes in these species. Silene latifolia, S. vulgaris, and Agrostemma githago were chosen ...
Fragile X Syndrome
Fragile X Syndrome

... in synaptic plasticity and maturation. Individuals with FXS present with intellectual disability, autism, hyperactivity, long face, large or prominent ears and macroorchidism at puberty and thereafter. Most of the young children with FXS will present with language delay, sensory hyper arousal and an ...
Complete Genome Sequence of Bacillus thuringiensis Strain 407 Cry-
Complete Genome Sequence of Bacillus thuringiensis Strain 407 Cry-

... B. thuringiensis strain 407 was isolated as a lepidopteran-active strain, and an acrystalliferous derivative, 407 Cry-, was produced through culturing at a high temperature (2). The 407 Cry- strain can be transformed easily and it can be used to perform targeted gene knockouts; therefore, the strain ...
Supplementary Data File Supplementary Figures Figure S1
Supplementary Data File Supplementary Figures Figure S1

... Table S10. Top ten statistically significant KEGG pathways (adjusted P-value < 0.01) in the two-group cancer versus normal comparisons. We report the top ten pathways or all the significant pathways if there were less than ten for A. AML vs 1000 Genomes, B. GBM vs 1000 Genomes, C. OVC vs 1000 Genom ...
Recent highlights of the China Rice Functional Genomics Program
Recent highlights of the China Rice Functional Genomics Program

... (Y. Liu, pers. commun.), which will make this molecular approach feasible. Manipulation of elite lines with the Rf1 gene could widen the donor lines used in hybrid rice breeding, thus potentially improving the grain quality of most hybrid rice lines. Candidates for several other genes important for ...
Evolution by the birth-and-death process in multigene
Evolution by the birth-and-death process in multigene

... The mouse MHC genes have also been studied extensively. The mouse class Ia genes are not orthologous with the human class Ia genes (24–26), and therefore different gene symbols are used for them (Fig. 2). Actually, most different orders of mammals seem to have nonorthologous class Ia genes. The numb ...
Brand, Veronica - Degenerate Primer Design using Computational Tools
Brand, Veronica - Degenerate Primer Design using Computational Tools

... software, but also by various researchers who have used the program to look for functional genes in samples as diverse as activated sludge and engineered anaerobic bioreactors (McMahon et al. ...
Fragile x syndrome
Fragile x syndrome

... • About 1 in 259 women carry fragile X and could pass it to their children. • About 1 in 800 men carry Fragile X; their daughters will also be carriers. • Large-scale population studies of Fragile X still need to be done, but it is clear that this is one of the most common genetic diseases in humans ...
Pluripotent cells (stem cells) - an der Universität Duisburg
Pluripotent cells (stem cells) - an der Universität Duisburg

... The cleaving amphibian egg first forms a morula, followed by the blastula stage, when a cavity called the blastocoele develops. At the gastrula stage, a blastopore is formed in the presumptive endoderm. It is through the blastopore that the endoderm, the mesendoderm on the leading edge of the mesode ...
Transposon stability and a role for conjugational transfer in adaptive mutability
Transposon stability and a role for conjugational transfer in adaptive mutability

... presence of the inducer Tet (13). For the episomal allele, the analysis was carried in the presence of streptomycin (Sm), conditions in which conjugal transfer to scavenger cells is required for detection of reversion (10), because the lacI33carrying cells are sensitive to Sm and the scavenger cells ...
Problems from Strickberger`s Genetics
Problems from Strickberger`s Genetics

... Human diseases directly involving antibody formation include -those ,in which little or no antibody is formed (agammaglobulinemias) and those that form large excesses of only one type of antibody or part of an antibody (multiple myelomas). In mice, the ability to form specific immune responses (i.e. ...
Biology Recap
Biology Recap

... 1953 Scientific Discovery of DNA and its Structure ■  Crick and Watson incorporated X-ray crystallography work of ...
Chapter 15
Chapter 15

... The Chromosome Theory of Inheritance: genes (allele pairs) are on chromosomes and homologous chromosomes segregate during meiosis (principle of segregation) and reunite during fertilization. If allele pairs are on different chromosomes they will sort independently (principle of independent assortme ...
Divergent Evolution and Evolution by the Birth-and
Divergent Evolution and Evolution by the Birth-and

... the evolution of the immunoglobulin heavy-chain variable-region (Vu) genes (Hood et al. 1975; Ohta 1980, 1983). Gojobori and Nei ( 1984), however, showed that Vu gene (often called “gene segment”) family in the mouse and human undergoes a very slow rate of concerted evolution, if any; that the exten ...
Microsoft Word (Chapter 3) - DORAS
Microsoft Word (Chapter 3) - DORAS

... MultAlin and Genedoc programs (section 2.8) were used to perform global sequence alignment of E. coli K12 FhuA and the results of the BLASTP search are illustrated in figure 3.4. Analysis of the FhuA homologues suggested a putative function in the transport of hydroxamate-type Fe3+-siderophores. To ...
to the complete text - David Moore`s World of Fungi
to the complete text - David Moore`s World of Fungi

... thousand, if we want to obtain a believable result. But there is a better way. Much more information is obtained from a cross if three rather than two genetic markers are followed. In three-point crosses, recombination frequencies are obtained in the usual way but they also allow the relative order ...
A, B, a
A, B, a

... • In diploid heterozygous for mutant alleles of the same gene, recombination can generate wild-type and double mutant alleles a1/a2  a+ and a1,2 • Rare event, 10-3 to 10-6, but in systems with large number of offspring, recombination can be used to map mutations within a gene Chapter 6: Eukaryote r ...
GENETIC CHARACTERIZATION OF NITRA RABBITS AND ZOBOR
GENETIC CHARACTERIZATION OF NITRA RABBITS AND ZOBOR

... In an attempt to characterize the two rabbit breeds concerning the shift on the genetic level we studied microsatellite and genetic markers associated with coat color. These two local rabbit breeds, Nitra rabbit (Ni) and Zobor rabbit (Zo) with different phenotypes have a common origin. Based on the ...
Türkiye, İzmir Sokak Kedilerinde Neonatal İzoeritrolizisle İlişkili
Türkiye, İzmir Sokak Kedilerinde Neonatal İzoeritrolizisle İlişkili

... CMAH enzyme produces N-glycolylneuraminic acid (Neu5Gc) derived from N-acetylneuraminic acid (Neu5Ac) through enzymatic hydroxylation [1]. Neu5Gc and Neu5Ac are two of the most abundant sialic acids and both of them are expressed in echinoderm to mammalians [1-4]. These sialic acids have significant ...
The Genetics of Microcephaly
The Genetics of Microcephaly

... affected for no definite reason and the medical tests that they undergo fail to provide any clues as to the cause. Some causes of microcephaly Genetic chromosome disorders Genetic single gene disorders Certain prenatal infections affecting the fetus Cerebrovascular accident in the fetus (stroke) Sev ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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