The amphioxus hairy family: differential fate after duplication.
... Genes in the hairy family encode class E of basic helixloop-helix (bHLH) transcription factors (Ledent and Vervoort, 2001). These are defined by (i) a proline in the sixth residue within the basic domain that allows them to bind preferentially to sequences refered as "Nboxes" in their target genes ( ...
... Genes in the hairy family encode class E of basic helixloop-helix (bHLH) transcription factors (Ledent and Vervoort, 2001). These are defined by (i) a proline in the sixth residue within the basic domain that allows them to bind preferentially to sequences refered as "Nboxes" in their target genes ( ...
Patterns of Inheritance
... scientists agree that phenotype depends on a complex interaction between genotype and environment, there is a lot of debate and controversy about the relative importance of these 2 factors, particularly for complex human traits. ...
... scientists agree that phenotype depends on a complex interaction between genotype and environment, there is a lot of debate and controversy about the relative importance of these 2 factors, particularly for complex human traits. ...
- Philsci
... The traditional organismal phylogenies fail to preserve this level of detail of genomic phylogenies in two ways. Firstly, the history of a genome includes both the movement of genes from parent to offspring in reproduction, but also the transfer of genetic material in gene duplication events occurri ...
... The traditional organismal phylogenies fail to preserve this level of detail of genomic phylogenies in two ways. Firstly, the history of a genome includes both the movement of genes from parent to offspring in reproduction, but also the transfer of genetic material in gene duplication events occurri ...
Formal Outline Introduction The Founding of PTC When Who How
... organic compound that allows the holder of a specific gene to taste the compound as bitter, slightly bitter, or completely tasteless. Respectively, these people are known as “tasters” and “nontasters.” Approximately 75% of Earth’s population can taste PTC, whereas 25% cannot. PTC was first discovere ...
... organic compound that allows the holder of a specific gene to taste the compound as bitter, slightly bitter, or completely tasteless. Respectively, these people are known as “tasters” and “nontasters.” Approximately 75% of Earth’s population can taste PTC, whereas 25% cannot. PTC was first discovere ...
pdf
... depth was determined after a quick analysis of the depth distribution of nitrite concentration in the water column from an initial cast. For the coastal stations, DNA samples were collected from the depth at which the DO was low; nitrite was not present at the sample depth at either coastal location ...
... depth was determined after a quick analysis of the depth distribution of nitrite concentration in the water column from an initial cast. For the coastal stations, DNA samples were collected from the depth at which the DO was low; nitrite was not present at the sample depth at either coastal location ...
Neonatal Hyperbilirubinemia and Organic Anion Transporting
... etiology (group I): This group included 65 newborn infants with gestational ages of 37 weeks and ages of < 10 days. Patients were excluded for the following reasons: congenital anomalies, increased hepatic enzyme levels, congenital hypothyroidism, sepsis, urinary tract infections, insufficient fee ...
... etiology (group I): This group included 65 newborn infants with gestational ages of 37 weeks and ages of < 10 days. Patients were excluded for the following reasons: congenital anomalies, increased hepatic enzyme levels, congenital hypothyroidism, sepsis, urinary tract infections, insufficient fee ...
Complex Signatures of Natural Selection at the Duffy Blood Group
... requires one to distinguish between the effects of natural selection and those of population history. This is a particularly difficult challenge in humans for two main reasons. First, the low levels of sequence variation provide little power to detect a significant reduction of polymorphism levels, ...
... requires one to distinguish between the effects of natural selection and those of population history. This is a particularly difficult challenge in humans for two main reasons. First, the low levels of sequence variation provide little power to detect a significant reduction of polymorphism levels, ...
Alu Human Polymorphism
... • The LINE (Long INterspersed Element) L1 supplies the reverse transcriptase needed for Alu to jump – L1 is a defective retrovirus – It nicks the DNA close to the sequence AATTTT – The AAAA of Alu transcript binds to the TTTT of the nicked DNA – the acts as a primer for the L1 to bind to ...
... • The LINE (Long INterspersed Element) L1 supplies the reverse transcriptase needed for Alu to jump – L1 is a defective retrovirus – It nicks the DNA close to the sequence AATTTT – The AAAA of Alu transcript binds to the TTTT of the nicked DNA – the acts as a primer for the L1 to bind to ...
Drosophila rhino Encodes a Female-Specific Chromo
... levels of gurken (grk), oskar (osk), bicoid (bcd), and decapentaplegic (dpp) transcripts are normal, with a slight delay in the appearance of bcd and dpp mRNAs. Mislocalization of grk and osk transcripts, however, suggests a defect in the microtubule reorganization that occurs during the middle stag ...
... levels of gurken (grk), oskar (osk), bicoid (bcd), and decapentaplegic (dpp) transcripts are normal, with a slight delay in the appearance of bcd and dpp mRNAs. Mislocalization of grk and osk transcripts, however, suggests a defect in the microtubule reorganization that occurs during the middle stag ...
Text S1: Genome-Wide High-Resolution Mapping of UV
... Analysis of sectored colonies derived from “single-cell” experiments. As described in the text, in some experiments, we irradiated G1-synchronized cells and micromanipulated the irradiated cells to specific locations on plates. Thus, sectored colonies generated from this procedure were derived from ...
... Analysis of sectored colonies derived from “single-cell” experiments. As described in the text, in some experiments, we irradiated G1-synchronized cells and micromanipulated the irradiated cells to specific locations on plates. Thus, sectored colonies generated from this procedure were derived from ...
Enhanced Detection of Longer Insertions and Deletions in Clinical
... found in the human genome and substantial amount of research, such as that by the International HapMap Consortium, has been focused on accurately mapping and identifying SNVs for human genetic variation studies [8]. However, in spite of being the second most common type of genomic alterations [9], i ...
... found in the human genome and substantial amount of research, such as that by the International HapMap Consortium, has been focused on accurately mapping and identifying SNVs for human genetic variation studies [8]. However, in spite of being the second most common type of genomic alterations [9], i ...
DNA Methylation Analysis
... Database9 (Genome Build 36). Additional markers provide increased resolution focused on 144 established cancer genes that have shown differential methylation patterns. To ensure the most important loci were represented, Illumina designed markers to cover nearly 1,000 cancer-related genes described i ...
... Database9 (Genome Build 36). Additional markers provide increased resolution focused on 144 established cancer genes that have shown differential methylation patterns. To ensure the most important loci were represented, Illumina designed markers to cover nearly 1,000 cancer-related genes described i ...
Systems and synthetic biology approaches to alter plant cell walls
... enabling high-precision engineering of biomass properties. In a seminal effort in higher precision engineering of cell wall properties, C4H gene was expressed under a xylem vessel cellspecific VND6 promoter and concomitantly the NST1 was expressed under the IRX8 promoter in Arabidopsis. Yang et al. ...
... enabling high-precision engineering of biomass properties. In a seminal effort in higher precision engineering of cell wall properties, C4H gene was expressed under a xylem vessel cellspecific VND6 promoter and concomitantly the NST1 was expressed under the IRX8 promoter in Arabidopsis. Yang et al. ...
Construction of plant BAC libraries This document
... 14. Cut the center gel block transversely at two places to yield three blocks (referred to from bottom to top as “x”, “y”, and “z”) of approximately equal size (FIGURE 1g). Stain the end pieces with BET, partially reconstruct the gel using the various stained pieces, and photograph. The unstained p ...
... 14. Cut the center gel block transversely at two places to yield three blocks (referred to from bottom to top as “x”, “y”, and “z”) of approximately equal size (FIGURE 1g). Stain the end pieces with BET, partially reconstruct the gel using the various stained pieces, and photograph. The unstained p ...
Control of GL2 expression in Arabidopsis leaves and trichomes
... • Because both GL1 and R are required to ectopically activate GL2, it is possible that GL1 and R function as a complex • A construct containing the GL1 gene with a myc epitope as an Nterminal fusion was generated – This same epitope fusion was made to a truncated version of the GL1 protein that expr ...
... • Because both GL1 and R are required to ectopically activate GL2, it is possible that GL1 and R function as a complex • A construct containing the GL1 gene with a myc epitope as an Nterminal fusion was generated – This same epitope fusion was made to a truncated version of the GL1 protein that expr ...
Similarity Searches on Sequence Databases: BLAST
... Choosing the right Parameters: sequence masking • When BLAST searches databases, it makes the assumption that the average composition of any sequence is the same as the average composition of the whole database. • However this assumption doesn’t hold all the time, some sequences have biased composi ...
... Choosing the right Parameters: sequence masking • When BLAST searches databases, it makes the assumption that the average composition of any sequence is the same as the average composition of the whole database. • However this assumption doesn’t hold all the time, some sequences have biased composi ...
Solving the shugoshin puzzle
... is mediated by conserved proteins called shugoshins (Japanese for ’guardian spirit’) (reviewed in Ref. [3]). The role of shugoshins in mouse meiosis was recently analyzed [1]. Both mouse shugoshin proteins, Sgo1 and Sgo2, are ubiquitously expressed in proliferating cells, and Sgo2 expression is high ...
... is mediated by conserved proteins called shugoshins (Japanese for ’guardian spirit’) (reviewed in Ref. [3]). The role of shugoshins in mouse meiosis was recently analyzed [1]. Both mouse shugoshin proteins, Sgo1 and Sgo2, are ubiquitously expressed in proliferating cells, and Sgo2 expression is high ...
Qβ replicase discriminates between legitimate and illegitimate
... they are completely converted into double helix. • Within the replicative complex, the template and the nascent strands are close to one another, which favors their annealing. • These stands immediately collapse into the double helix under action of proteases and detergents that cannot affect the st ...
... they are completely converted into double helix. • Within the replicative complex, the template and the nascent strands are close to one another, which favors their annealing. • These stands immediately collapse into the double helix under action of proteases and detergents that cannot affect the st ...
O4 M.A. Rouf Mian
... northern soybean growing region of the USA in 2000. By 2004, 80% of the U.S. soybean field was infested by SA. The SA is native to southeastern and eastern Asia and it is long been a pest of soybean in many Asian countries. Three plant introductions (PIs) (PI 243540, PI 567301B, and PI 567324) were ...
... northern soybean growing region of the USA in 2000. By 2004, 80% of the U.S. soybean field was infested by SA. The SA is native to southeastern and eastern Asia and it is long been a pest of soybean in many Asian countries. Three plant introductions (PIs) (PI 243540, PI 567301B, and PI 567324) were ...
The CpG island methylator phenotype (CIMP) in
... explained by Toyota et al. (16). CpG island methylator phenotype (CIMP) is a subset of colorectal cancers that happen through an epigenetic instability pathway and that are characterized by vast hypermethylation of promoter CpG island sites, resulting in the inactivation of several tumor suppressor ...
... explained by Toyota et al. (16). CpG island methylator phenotype (CIMP) is a subset of colorectal cancers that happen through an epigenetic instability pathway and that are characterized by vast hypermethylation of promoter CpG island sites, resulting in the inactivation of several tumor suppressor ...
Handbook on SMA genetics_final_051209
... Short compendium of SMA genetics SMA is clinically classified into three subgroups: acute (type 1), intermediate (type 2) and mild (type 3). The estimated birth prevalence is about 1/10.000 and the carrier frequency is 1/35. Two homologue copies of the SMN gene are playing a central role in SMA: SMN ...
... Short compendium of SMA genetics SMA is clinically classified into three subgroups: acute (type 1), intermediate (type 2) and mild (type 3). The estimated birth prevalence is about 1/10.000 and the carrier frequency is 1/35. Two homologue copies of the SMN gene are playing a central role in SMA: SMN ...
Point Mutation in Intron Sequence Causes Altered Carboxyl
... Schmidt and Bradfield, 1996). The molecular mechanism of CYP1A1 induction by TCDD has been elucidated in detail. TCDD has the highest affinity of all ligands for the AhR (Safe, 1986). Upon binding TCDD, the AhR sheds its chaperones, two hsp90 molecules, along with other associated proteins and trans ...
... Schmidt and Bradfield, 1996). The molecular mechanism of CYP1A1 induction by TCDD has been elucidated in detail. TCDD has the highest affinity of all ligands for the AhR (Safe, 1986). Upon binding TCDD, the AhR sheds its chaperones, two hsp90 molecules, along with other associated proteins and trans ...
January 1997 Biology 30 Grade 12 Diploma Examination
... such as surfaces of reproductive organs and organs of the urinary system. This misplaced endometrial tissue responds to hormones in the blood in the same way as the normal endometrium. This causes pain and may severely damage the organ to which the tissue is attached. Women who have endometriosis do ...
... such as surfaces of reproductive organs and organs of the urinary system. This misplaced endometrial tissue responds to hormones in the blood in the same way as the normal endometrium. This causes pain and may severely damage the organ to which the tissue is attached. Women who have endometriosis do ...