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PracticeFinalSP2003
PracticeFinalSP2003

... b) amino acids can sometimes exist as ‘zwitterions’. What does this mean and why? c) if R represents a H atom, the amino acid is called glycine (gly),. Draw the molecule and tell me if glyciene an enantiomer. If it does, mark with an asterisk (*) the chiral carbon and draw the enantiomer. d) if R re ...
Proteins - chem.uwec.edu
Proteins - chem.uwec.edu

... At lower pH values the carbolylate group becomes protonated and the amino acid has a net charge of +1. b. At higher pH values the amino group becomes unprotonated and the amino acid has a net charge of -1. ...
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Fat Metabolism during One Hours Exercise on High and Low Doses
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... l3COZenrichment (from [ 1-13C]palmitate) and 14C0, specific activity (SA) (from [1-14C] acetate) were measured over the last 20 min to determine the recovery of label from acetate and to calculate plasma FFA oxidation rates. Acetate directly enters the TCA cycle and, under the present experimental c ...
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Lehninger Principles of Biochemistry 5/e
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OCHeM.com ©1999 Thomas Poon Amino Acids, Peptides, and
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Citric acid cycle



The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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