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Cells, Tissues and Organs of the Immune System
Cells, Tissues and Organs of the Immune System

... granules • Important in some allergic responses • Critical to response to parasites • Bind circulating Abs and release histamineincreasing permeability of blood vessels ...
Transplantation immunity
Transplantation immunity

Spring 2008 - Antelope Valley College
Spring 2008 - Antelope Valley College

... The class of antibody that is involved in allergic reactions is ____________________________. ...
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HIV/AIDS - Artec Inc.
HIV/AIDS - Artec Inc.

... White blood cells circulate in the blood system, immunosurveilling, identifying non-self cells and cellular debris. When devouring takes place, white blood cells churn out a strong chemical signal in the form of Cytokines, such as Interleukin (IL). IL in turn stimulates the immune system to massivel ...
MCQs: What cell types can be made tolerant? T
MCQs: What cell types can be made tolerant? T

... (b) No self-reactive T cells can be found in healthy normal subjects. (c) Naïve T cells need more than one signal in order to become activated (d) B-cell tolerance is more important than T-cell tolerance in the prevention of autoimmunity (e) class II MHC molecules are expressed on most cells ...
Immunity - McCarter Anatomy & Physiology
Immunity - McCarter Anatomy & Physiology

... Provide a specific immune response to infectious diseases. 2 types: - T-cells –mature in thymus - B-cells mature in bone marrow then are found in lymph nodes and spleen ...
Innate Immunity
Innate Immunity

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LECTURE OUTLINE

... foreign molecules or cells, after which they proliferate and become activated. The spleen filters the blood. Lymph nodes are packed with B and T cells. 13.2 Innate and Acquired Immunity Immunity is the body’s capability of removing or killing foreign substances, pathogens, and cancer cells. Mechanis ...
Defence Against the Dark Arts..... or Infectious Diseases
Defence Against the Dark Arts..... or Infectious Diseases

... to as a phagocyte) All cells have proteins on their cell membranes called ANTIGENS Antigens act as identity markers. Macrophages recognize body cells of the host by its antigens Foreign invaders will have different cell surface antigens which will cue macrophages to get rid of them ...
Natural Killer Cells
Natural Killer Cells

... Bacteria require iron and zinc. During a fever the liver hoards these minerals. Fever also increases the metabolic rate which delivers nutrients, white blood cells, etc. to the damage zone. When a fever is bad: If a fever gets too high it causes a “scrambling” of enzymes and other body proteins. ...
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... Bone Marrow- produces all immune system cells ...
CHAPTER 2 Immune Response to Infection
CHAPTER 2 Immune Response to Infection

... In the bone marrow are marked to become T cells, B cells, or null cells B cells may become plasma cells which produces antibodies T cells secrete cytokines which are effector molecules for multiple immunocytes and somatic cells. 5. Uncommitted null cells may become natural killer (NK) cells which ki ...
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CD4 and HIV

... – signaling other cells in immune system – healthy: 800~1200 CD4+ T cells/mm3 – AIDS: < 200 CD4+ T cells/mm3 • less densely on macrophages, dendritic cell* and microglial cells ...
Review questions for Immune System
Review questions for Immune System

... 14. What are the primary effects of histamine in inflammation? What role does histamine play in homeostasis (not inflammation)? ...
The Immune System Second Edition
The Immune System Second Edition

... Toxoplasma gondii – generates its own vesicle inside the cells that won’t fuse with the lysosome to protect it and its peptides from being available for presentation via MHCI. ...
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... disease usually affects the lungs, but it can also affect other parts of the body, such as the brain, the kidneys, or the spine; active ...
Immune System - WordPress.com
Immune System - WordPress.com

... These two elements are the body’s first line of defense to prevent pathogens from entering and causing disease.  Skin- Few pathogens can pass through the tough layer of dead skin cells that surrounds the body.  Tears and saliva-contain enzymes that destroy or disable many pathogens.  Mucous membr ...
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Name: Date: Period: _____ The Immune Response: Web Analysis

... 3. If antibodies are present, they can attach to the microbe and mark it for destruction 4. Example microbes – bacteria, viruses, fungi, etc. 1. Natural – do not need an injection for immunity 2. Acquired – immunity (antibodies) is transferred from one person to another via vaccine ; or once specifi ...
Ch. 8 notes
Ch. 8 notes

... – TINY WHITE BLOOD CELLS ATTACK INVADING ORGANISMS AND GOBBLE THEM UP – WHITE BLOOD CELLS LEAVE THE BLOOD AND ENTER NEARBY TISSUE – LARGER WHITE BLOOD CELLS SOON JOIN THEM DESTROYING HARMFUL BACTERIA ...
Molecular Immunology
Molecular Immunology

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IMMUNITY Body Defenses Nonspecific Body Defenses [In native

... to 3 days, directed by thymic hormones (thymosin and others). Within the thymus, the immature lymphocytes divide rapidly and their numbers increase enormously, but only those maturing T cells have the ability to identify foreign antigens. B cells develop immunocompetence in bone marrow, but little i ...
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Reading Chapter 27 NERVOUS SYSTEM Neurons

... common reservoir is cats. Intracellular parasite. Humans become infected by 2 sources: 1) improperly cooked meats 2) infective oocysts from cat feces. Illness is affected by immune status of the person reactivation of previously latent infection common. Can be benign and asymptomatic with symptoms o ...
File - Mr. Shanks` Class
File - Mr. Shanks` Class

... engulf an unwelcome microbe. ...
Symbiosis and Host Defenses
Symbiosis and Host Defenses

... • B lymphocytes produce antibodies which are special proteins that bind to foreign molecules (antigens) and facilitate an immune response – Plasma cells – Memory B cells • Natural Killer cells Kill virus- infected cells, bacteria and cancer cells extracellularly • T lymphocytes differentiate into se ...
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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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