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-ATPases:
-ATPases:

... P-type ATPase database web-site (http://biobase.dk/∼axe/Patbase.html). A phylogenetic tree based on the available amino acid sequences reveals the presence of a number of H+-ATPase subfamilies (Figure 3). Arabidopsis AHA1, TABLE 1 Overview of the plasma membrane H+-ATPase gene family in Arabidopsis ...
Downloaded - The Journal of Cell Biology
Downloaded - The Journal of Cell Biology

... more specific targets within the TGF-1 profibrotic pathway in dystrophic muscle. TGF-1 is secreted as a latent protein that is converted to its active form pericellularly by proteolytic processing (mainly via plasmin protease cleavage) and/or by integrininduced conformational modification (Pedroja ...
Reduced Vglut2/Slc17a6 gene expression levels
Reduced Vglut2/Slc17a6 gene expression levels

... rewards. This finding led us to here address the hypothesis that the Pitx2/Vglut2 co-expressing ...
THE ROLE OF NODAL SIGNALING IN PATTERNING THE
THE ROLE OF NODAL SIGNALING IN PATTERNING THE

... network underlying pattern formation and cell type specification during early zebrafish embryonic development. I have been particularly interested in the establishment of the primary body axes and formation of the three germ layers. Segregation of cells into three germ layers is one of the earliest ...
like skin disease in mice
like skin disease in mice

... Bloch9, Hans-Dietmar Beer10 & Sabine Werner1 ...
View PDF - CiteSeerX
View PDF - CiteSeerX

... PXR is efficaciously activated by several steroids, including naturally occurring pregnanes and synthetic glucocorticoids and antiglucocorticoids. Thus, PXR combines features of both the steroid and nonsteroid nuclear receptors. We suggest that PXR defines a novel steroid hormone signaling pathway t ...
In Vitro Assays Demonstrate That Pollen Tube Organelles Use
In Vitro Assays Demonstrate That Pollen Tube Organelles Use

... ability to glide microtubules in the in vitro motility assay, for the presence of microtubule-stimulated ATPase activity, and for cross-reactivity with anti-kinesin antibodies. We identified and characterized a 105-kD organelle-associated motor protein that is functionally, biochemically, and immuno ...
Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects
Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects

... The heart muscle is characterized by a large volume of mitochondria due to its high energy demand . Mitochondria produce ATP primarily by utilizing the electrochemical gradient formed by electron transfer via the electron transport chain located on the inner mitochondrial membrane. However, electron ...
Regulation of axon growth by the JIP1–AKT axis
Regulation of axon growth by the JIP1–AKT axis

... while the cell body and dendrites integrate this information by making multiple synaptic connections. The polarisation of neurons is therefore essential for the formation of neuronal networks and the function of the brain (Barnes and Polleux, 2009). A number of factors determining axon formation and ...
Chitin and Chitosan in Fungi - Wiley-VCH
Chitin and Chitosan in Fungi - Wiley-VCH

... have been assigned (cf. Table 1). In general, b-glycosyltransferases, including cellulose and chitin synthases, have a highly conserved common motif `D, D, D35Q(R,Q )XRW'. The second residue (R or Q ) in the Q(R,Q )XRW sequence is probably involved in determining the degree of polymerization (DP ) o ...
DC-derived exosomes bear molecules involved in
DC-derived exosomes bear molecules involved in

... functional MHC-I/peptide complexes to DC 24, it is unclear whether exosomes cluster or fuse with DC, or if they are internalized and processed, as occurs with vesicles derived from apoptotic cells 2-5. Herein we demonstrate that exosomes are internalized efficiently by DC. Targeting of exosomes to D ...
Structure and function of the notochord: an essential
Structure and function of the notochord: an essential

... as a source of midline signals that pattern surrounding tissues and as a major skeletal element of the developing embryo. Genetic and embryological studies over the past ...
Blood Vessel Patterning at the Embryonic Midline
Blood Vessel Patterning at the Embryonic Midline

... compound that selectively binds to endothelial cells in many organisms (Levine et al., 2003). 2. Zebrafish (Danio rerio) There are several advantages to this rather new model of vertebrate development. The embryo is transparent and free-living, facilitating the acquisition of descriptive information ...
Ammonium toxicity and potassium limitation in yeast. 
Ammonium toxicity and potassium limitation in yeast. 

... per se is lethal to S. cerevisiae. To examine further the MEP over-expressing strains, we grew them in a phosphate-limited chemostat with galactose as a carbon source (Figure 9A). The media contained high (13 mM) potassium and standard (76 mM) ammonium concentrations. Nevertheless, MEP1 and MEP3 ove ...
Ammonium toxicity and potassium limitation in yeast.
Ammonium toxicity and potassium limitation in yeast.

... To examine further the MEP over-expressing strains, we grew them in a phosphate-limited chemostat with galactose as a carbon source (Figure 9A). The media contained high (13 mM) potassium and standard (76 mM) ammonium concentrations. Nevertheless, MEP1 and MEP3 over-expressing strains were not able ...
Carbon partitioning in sugarcane (Saccharum species)
Carbon partitioning in sugarcane (Saccharum species)

... turn are transported by hexose carriers, with sucrose re-synthesis occurring in the cytoplasm prior to vacuolar storage (Figure 1). Transporters of the plasma membrane appear to play an important role not only in phloem loading and unloading, but also in transferring sucrose between apoplastic and s ...
An alternative, arginase-independent pathway for arginine Kluyveromyces lactis involves metabolism in
An alternative, arginase-independent pathway for arginine Kluyveromyces lactis involves metabolism in

... proline or ammonia as a sole nitrogen source (Fig. 2). Consistent with earlier studies (Brandriss and Magasanik, 1980; Brandriss and Falvey, 1992), the S. cerevisiae strains IMK435 (car1Δ), IMK436 (car2Δ) and IMK445 (pro3Δ) were unable to grow on arginine as a sole nitrogen source. Furthermore, grow ...
Selenocysteine insertion directed by the 3′
Selenocysteine insertion directed by the 3′

... as a signal for termination of protein synthesis. To distinguish between these two functions of UGA, a designated RNA structure, Sec insertion sequence (SECIS) element (10,11), is present in selenoprotein mRNAs and directs Sec incorporation into selenoproteins (11,12). In both prokaryotes and eukary ...
patterning mechanisms controlling vertebrate limb development
patterning mechanisms controlling vertebrate limb development

... another, so that a limb ends up looking very different from a tooth, even though the underlying molecular and cellular mechanisms that have sculpted both structures are remarkably similar. Among the structures and organs mentioned above, the vertebrate limb bud is clearly an excellent experimental m ...
Drosophila Xpd Regulates Cdk7 Localization, Mitotic Kinase
Drosophila Xpd Regulates Cdk7 Localization, Mitotic Kinase

... complexes. In vitro phosphorylation studies using mammalian kinase complexes showed that free CAK activates cell cycle Cdk targets, whereas TFIIH-associated CAK acts in transcription by phosphorylating RNA polymerase II [6–8]. These two different types of substrates share no obvious resemblance, but ...
Characterization of the Visceral Endoderm Components in Early
Characterization of the Visceral Endoderm Components in Early

... Early post-implantation vertebrate embryos are shaped by complex cellular and molecular mechanisms. In mice, the visceral endoderm, an extraembryonic cell lineage that appears before gastrulation, provides several important functions such as nutrition and mechanical protection. My thesis research fo ...
Paramecium as a bioassay system for elucidation of cytotoxicity and
Paramecium as a bioassay system for elucidation of cytotoxicity and

... in culture medium containing nutritive bacteria. Contrary to this effect, no cytotoxicity was detected in survival tests using the modified Dryl’s solution (K-DS) that is used as a buffered saline of culture medium. The cytotoxicity of CNF suggests an interaction between CNF and the components in cu ...
Incorporating key position and amino acid residue features to
Incorporating key position and amino acid residue features to

... Furthermore, some of these tools were only published as a method and did not provide a user-friendly web service, and this makes predictions a laborious or impossible task. Even those tools with web services either do not support stringency adjustment or only support several predefined stringency le ...
Contribution of microtubule growth polarity and flux to spindle
Contribution of microtubule growth polarity and flux to spindle

... tubulin flux (2 ␮m/minute) equals the speed of chromatidseparation. With these findings we identified spatially coordinated microtubule growth dynamics and microtubule flux-based chromosome-separation as important facets of plant spindle operation. Supplementary material available online at http://j ...
Root cap development in rice CORRESPONDING AUTHOR
Root cap development in rice CORRESPONDING AUTHOR

... columella root cap cells (Fig. 1I); whereas starch granules in lateral root cap cells could only be readily seen at 8 DAA (Fig. 1J). Starch granule formation in the columella and lateral root cap cells indicates that these cells are fully differentiated and thus the root cap might be fully functiona ...
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