Etude in vitro de la stéatose hépatique induite par la - HAL
... cytoplasmic monolayer of the ER membrane via a hydrophobic domain located between aa 120 and aa 175 [17, 49]. This enables it to move along this monolayer towards the surface of the lipid droplets [48]. This hydrophobic domain, which mediates targeting to the lipid droplets, is not found in the core ...
... cytoplasmic monolayer of the ER membrane via a hydrophobic domain located between aa 120 and aa 175 [17, 49]. This enables it to move along this monolayer towards the surface of the lipid droplets [48]. This hydrophobic domain, which mediates targeting to the lipid droplets, is not found in the core ...
REGULATION OF CDC14: PATHWAYS AND CHECKPOINTS OF
... highly homologous signaling pathway, known as the Septation Initiation Network (SIN) (34,35). The SIN was identified by genetic analysis aimed at understanding the control of cytokinesis rather than cyclin degradation and mitotic exit. Surprisingly, SIN does not appear to be required for the activat ...
... highly homologous signaling pathway, known as the Septation Initiation Network (SIN) (34,35). The SIN was identified by genetic analysis aimed at understanding the control of cytokinesis rather than cyclin degradation and mitotic exit. Surprisingly, SIN does not appear to be required for the activat ...
Microbiology with Diseases by Body System, 3e
... Bloom's Rank: Application Section: Clinical Considerations in Prescribing Antimicrobial Drugs 9) Brain and spinal cord infections are difficult to treat because most antimicrobial drugs cannot diffuse out of the blood into these organs. Answer: TRUE Bloom's Rank: Comprehension Section: Clinical Cons ...
... Bloom's Rank: Application Section: Clinical Considerations in Prescribing Antimicrobial Drugs 9) Brain and spinal cord infections are difficult to treat because most antimicrobial drugs cannot diffuse out of the blood into these organs. Answer: TRUE Bloom's Rank: Comprehension Section: Clinical Cons ...
Biogenesis, Turnover, and Mode of Action of Plant
... In plants, pri-miRNA stem-loops are processed into short doublestranded RNAs (dsRNAs) consisting of mature miRNA guide and passenger (miRNA*) strands with 2-nucleotide 39 overhangs by a family of four DCL RNase III endonucleases (Margis et al., 2006; Figure 1). Structural features of the pri-miRNA s ...
... In plants, pri-miRNA stem-loops are processed into short doublestranded RNAs (dsRNAs) consisting of mature miRNA guide and passenger (miRNA*) strands with 2-nucleotide 39 overhangs by a family of four DCL RNase III endonucleases (Margis et al., 2006; Figure 1). Structural features of the pri-miRNA s ...
PowerPoint Template
... guanylyl cyclase from GTP. Although the guanylyl cyclases catalyze a similar reaction as the adenylyl cyclases, the two enzyme classes differ considerably in structure and mechanism of activation. The guanylyl cyclases can be divided into three groups according to the number of transmembrane segme ...
... guanylyl cyclase from GTP. Although the guanylyl cyclases catalyze a similar reaction as the adenylyl cyclases, the two enzyme classes differ considerably in structure and mechanism of activation. The guanylyl cyclases can be divided into three groups according to the number of transmembrane segme ...
Review Article S-Layer Glycoproteins and Flagellins: Reporters of
... beyond the haloarchaeal plasma membrane at a distance of 8 nm, with a periplasmic-like space being formed from morphological subunits assuming an “inverted-parabola shape”. Enzymatic iodination of Hbt. salinarum surface proteins, together with proteolytic treatment, revealed this surface (S)layer to ...
... beyond the haloarchaeal plasma membrane at a distance of 8 nm, with a periplasmic-like space being formed from morphological subunits assuming an “inverted-parabola shape”. Enzymatic iodination of Hbt. salinarum surface proteins, together with proteolytic treatment, revealed this surface (S)layer to ...
Facilitated Hexose Diffusion in Kinetoplastida
... Hexose transporters in Kinetoplastida 185 The T. brucei bloodstream form transporter, THT1, lacks potential N-linked glycosylation sites on any of the predicted extracellular loops. THT1 does contain one N-glycosylation consensus sequence (Asn-7), although this is located on the amino terminal tail ...
... Hexose transporters in Kinetoplastida 185 The T. brucei bloodstream form transporter, THT1, lacks potential N-linked glycosylation sites on any of the predicted extracellular loops. THT1 does contain one N-glycosylation consensus sequence (Asn-7), although this is located on the amino terminal tail ...
Hierarchies of plant stiffness
... shape by the pattern of branching [3,8]. However, in a small herbaceous annual such as Arabidopsis, these factors are less important, and have not been studied. For some background on stiffness at the whole plant level, we refer you to [8–12]. 2.2. Organ level As primary load-bearing structures for ...
... shape by the pattern of branching [3,8]. However, in a small herbaceous annual such as Arabidopsis, these factors are less important, and have not been studied. For some background on stiffness at the whole plant level, we refer you to [8–12]. 2.2. Organ level As primary load-bearing structures for ...
pdf file - John Innes Centre
... DMI1 and this dominant-negative mutant protein we show that DMI1 increases the sensitivity of a sodium- and lithiumhypersensitive yeast (Saccharomyces cerevisiae) mutant toward those ions and that the C-terminal domain plays a central role in regulating this response. We also show that DMI1 greatly ...
... DMI1 and this dominant-negative mutant protein we show that DMI1 increases the sensitivity of a sodium- and lithiumhypersensitive yeast (Saccharomyces cerevisiae) mutant toward those ions and that the C-terminal domain plays a central role in regulating this response. We also show that DMI1 greatly ...
(2009). Age determination and growth in the male South African fur
... - to determine the rates and direction of osmotic water flow in problems involving both living and artificial systems. Diffusion of water and the role of aquaporins Nernst Equation to describe the movement of charge species such as Na+, H+, and amino acids ...
... - to determine the rates and direction of osmotic water flow in problems involving both living and artificial systems. Diffusion of water and the role of aquaporins Nernst Equation to describe the movement of charge species such as Na+, H+, and amino acids ...
Sodium in smooth muscle relaxation - AJP
... et al. (26). This estiquestration by sarcoplasmic reticulum and/or mitochonmate may be an approximation of the real value because dria. Attempts to demonstrate active extracellular it is not certain whether the disposition of lanthanum is transport of calcium in taenia coli or uterus have not wholly ...
... et al. (26). This estiquestration by sarcoplasmic reticulum and/or mitochonmate may be an approximation of the real value because dria. Attempts to demonstrate active extracellular it is not certain whether the disposition of lanthanum is transport of calcium in taenia coli or uterus have not wholly ...
PDF
... apical domain, leading to its release from the cortex. Because the Par3-aPKC complex is absent from the basolateral domain, Lgl cannot be phosphorylated in this domain and thus remains localised to the cortex (Betschinger et al., 2003). In Drosophila neuroblasts, basolaterally localised Lgl [L(2)gl ...
... apical domain, leading to its release from the cortex. Because the Par3-aPKC complex is absent from the basolateral domain, Lgl cannot be phosphorylated in this domain and thus remains localised to the cortex (Betschinger et al., 2003). In Drosophila neuroblasts, basolaterally localised Lgl [L(2)gl ...
Acquisition, Conservation, and Loss of Dual
... distinguish between organelle-specific signals. In addition to dual targeting to mitochondria and plastids, dual targeting of proteins to mitochondria and peroxisomes has also been reported (Carrie et al., 2008, 2009b). The mechanism of targeting differs in that proteins dual targeted to mitochondria ...
... distinguish between organelle-specific signals. In addition to dual targeting to mitochondria and plastids, dual targeting of proteins to mitochondria and peroxisomes has also been reported (Carrie et al., 2008, 2009b). The mechanism of targeting differs in that proteins dual targeted to mitochondria ...
File
... Larynx is an organ that is responsible for voice production. It is situated below the tongue and hyoid bone and between great blood vessels of the neck and lies at the level of 4th, 5th & 6th cervical vertebrae. It opens above into laryngeal part of pharynx, and below is continuous with trachea. Lar ...
... Larynx is an organ that is responsible for voice production. It is situated below the tongue and hyoid bone and between great blood vessels of the neck and lies at the level of 4th, 5th & 6th cervical vertebrae. It opens above into laryngeal part of pharynx, and below is continuous with trachea. Lar ...
Microfluidic devices for drug discovery and analysis
... improvement in isolation techniques, identification of complex systems that are responsible for a drug’s pharmacological response has evolved to be the new approach in identification of drug targets and it has reduced the use of living organisms and living tissues (Terstappen et al., 2007). Drug tar ...
... improvement in isolation techniques, identification of complex systems that are responsible for a drug’s pharmacological response has evolved to be the new approach in identification of drug targets and it has reduced the use of living organisms and living tissues (Terstappen et al., 2007). Drug tar ...
Characterization of the ftsYEX operon of Escherichia coli
... of a nascent polypeptide is recognized by a ribonucleic particle and escorted to a receptor or docking protein. The targeted protein would then be exported across the membrane of the endoplasmic reticulum into the lumen to continue its journey to the Golgi apparatus and beyond. For his insights into ...
... of a nascent polypeptide is recognized by a ribonucleic particle and escorted to a receptor or docking protein. The targeted protein would then be exported across the membrane of the endoplasmic reticulum into the lumen to continue its journey to the Golgi apparatus and beyond. For his insights into ...
An analysis of the response to gut induction in the C. elegans embryo
... EMS cells isolated before gut induction had occurred (1013 minutes before cytokinesis began in EMS) divided to form two daughters, both of which produced body wall muscle and pharyngeal muscle, but no gut or hypodermis, suggesting that both daughters differentiate as MS-like lineages, as MS normally ...
... EMS cells isolated before gut induction had occurred (1013 minutes before cytokinesis began in EMS) divided to form two daughters, both of which produced body wall muscle and pharyngeal muscle, but no gut or hypodermis, suggesting that both daughters differentiate as MS-like lineages, as MS normally ...
Chapter 4 - Neurasync
... threaded into the lysosomal lumen, in an ATP-dependent fashion. This process is assisted by a resident lysosomal chaperone, lys Hsc70. The substrate is then finally degraded into amino acids. For this process to work optimally, lysosomal membrane levels and conformation of Lamp2a are critical. The m ...
... threaded into the lysosomal lumen, in an ATP-dependent fashion. This process is assisted by a resident lysosomal chaperone, lys Hsc70. The substrate is then finally degraded into amino acids. For this process to work optimally, lysosomal membrane levels and conformation of Lamp2a are critical. The m ...
A motif of eleven amino acids is a structural adaptation that
... charge movement that arises from the redistribution of charged ‘voltage sensors’ across the membrane (Ashmore, 1989; SantosSacchi, 1991). We first measured NLC from gerbil prestinexpressing human embryonic kidney (HEK) cells and an example is shown in Fig. 2B. Gerbil prestin produced a bell-shaped r ...
... charge movement that arises from the redistribution of charged ‘voltage sensors’ across the membrane (Ashmore, 1989; SantosSacchi, 1991). We first measured NLC from gerbil prestinexpressing human embryonic kidney (HEK) cells and an example is shown in Fig. 2B. Gerbil prestin produced a bell-shaped r ...
+Tec - Blood Journal
... Louis, MO) and injected into rabbits to raise anti-Tec serum against its SH3 domain. For boosting, the protein was mixed withincomplete Freund’s adjuvant (Sigma). Transient expression in COS-I cells. The tec type IV cDNA was subcloned into an expression vector, pSSRal’ to generate the pSSRa/tec plas ...
... Louis, MO) and injected into rabbits to raise anti-Tec serum against its SH3 domain. For boosting, the protein was mixed withincomplete Freund’s adjuvant (Sigma). Transient expression in COS-I cells. The tec type IV cDNA was subcloned into an expression vector, pSSRal’ to generate the pSSRa/tec plas ...
Clathrin in mitotic spindles - AJP-Cell
... A third possibility is that the anti-clathrin antibodies may be recognizing a closely related isoform of clathrin with a novel function in the mitotic spindle. Both of the anti-clathrin heavy chain MAbs bind to regions of clathrin heavy chain that are highly conserved between the conventional and “m ...
... A third possibility is that the anti-clathrin antibodies may be recognizing a closely related isoform of clathrin with a novel function in the mitotic spindle. Both of the anti-clathrin heavy chain MAbs bind to regions of clathrin heavy chain that are highly conserved between the conventional and “m ...