The Role of Mitochondria in Cholestatic Liver Injury
... on in cholestasis disease. The mitochondrial content per cell is considered to be controlled primarily by biogenesis.(23) In the compensation stage, mitochondrial content is increased and in the damaged stage, it is decreased as a result of regulation of oxidative stress.(14) A reduced activity of t ...
... on in cholestasis disease. The mitochondrial content per cell is considered to be controlled primarily by biogenesis.(23) In the compensation stage, mitochondrial content is increased and in the damaged stage, it is decreased as a result of regulation of oxidative stress.(14) A reduced activity of t ...
Print - Circulation
... Experiments of this type reveal that the various subunits modulate sensitivity to dihydropyridine agonists, kinetics, and voltage dependence of activation and inactivation. The broad conclusion is that all subunits are required before the channel can fully express its native properties, although it ...
... Experiments of this type reveal that the various subunits modulate sensitivity to dihydropyridine agonists, kinetics, and voltage dependence of activation and inactivation. The broad conclusion is that all subunits are required before the channel can fully express its native properties, although it ...
Communications between Mitochondria, the Nucleus, Vacuoles
... aging of mitotically competent human cell types, while yeast chronological aging is believed to mimic aging of post-mitotic human cell types. Emergent evidence implies that various organelle-organelle and organelle-cytosol communications play essential roles in chronological aging of S. cerevisiae. ...
... aging of mitotically competent human cell types, while yeast chronological aging is believed to mimic aging of post-mitotic human cell types. Emergent evidence implies that various organelle-organelle and organelle-cytosol communications play essential roles in chronological aging of S. cerevisiae. ...
Characterization of the Cytosolic Proteins Involved in the Amoeboid
... retraction, similar to that seen in conventional actin-based cells. However, instead of actin, these cells power their movement through modulation of the major sperm protein (MSP) cytoskeleton. MSP forms dense filament meshworks that pack the sperm lamellipod. Protrusion is associated with the assem ...
... retraction, similar to that seen in conventional actin-based cells. However, instead of actin, these cells power their movement through modulation of the major sperm protein (MSP) cytoskeleton. MSP forms dense filament meshworks that pack the sperm lamellipod. Protrusion is associated with the assem ...
measuring force in the developing zebrafish embryo using
... In addition to large-scale movement of tissue in sheets, changes in force are also capable of driving migration of cells acting as independent entities. This is particularly evident in a phenomenon called differential adhesion. According to the differential adhesion hypothesis, cells segregate base ...
... In addition to large-scale movement of tissue in sheets, changes in force are also capable of driving migration of cells acting as independent entities. This is particularly evident in a phenomenon called differential adhesion. According to the differential adhesion hypothesis, cells segregate base ...
Subcellular trafficking kinetics of GLUT4 mutated at the N
... case of TGN38, both a transmembrane domain and a β-turn type of motif [17,18]. GLUT4 has several potential targeting domains and evidence has been presented suggesting that all three types of motif may be involved in GLUT4 trafficking. Piper et al. [19] have shown that GLUT1}GLUT4 and asialoglycopro ...
... case of TGN38, both a transmembrane domain and a β-turn type of motif [17,18]. GLUT4 has several potential targeting domains and evidence has been presented suggesting that all three types of motif may be involved in GLUT4 trafficking. Piper et al. [19] have shown that GLUT1}GLUT4 and asialoglycopro ...
CLC Chloride Channels in Caenorhabditis elegans*
... completion of the C. elegans Genome Project (19) revealed that there is just one additional CLC gene in its genome, bringing the total number to six. Sequence comparison and hydropathy analysis revealed that all predicted CLC proteins from C. elegans share domains D1 through D12 with their mammalian ...
... completion of the C. elegans Genome Project (19) revealed that there is just one additional CLC gene in its genome, bringing the total number to six. Sequence comparison and hydropathy analysis revealed that all predicted CLC proteins from C. elegans share domains D1 through D12 with their mammalian ...
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... Bloom's Rank: Application Section: Clinical Considerations in Prescribing Antimicrobial Drugs 9) Brain and spinal cord infections are difficult to treat because most antimicrobial drugs cannot diffuse out of the blood into these organs. Answer: TRUE Bloom's Rank: Comprehension Section: Clinical Cons ...
... Bloom's Rank: Application Section: Clinical Considerations in Prescribing Antimicrobial Drugs 9) Brain and spinal cord infections are difficult to treat because most antimicrobial drugs cannot diffuse out of the blood into these organs. Answer: TRUE Bloom's Rank: Comprehension Section: Clinical Cons ...
Planctomycetes – a phylum of emerging interest for
... Ultrastructure of eukaryote nuclear envelope and pore complexes also does not favour endosymbiotic origins for nuclei (Poole & Penny, 2001). The various stages needed for endogenous membrane enfolding of the genome may be represented ‘frozen’ in different planctomycete genera. Planctomycetes form a ...
... Ultrastructure of eukaryote nuclear envelope and pore complexes also does not favour endosymbiotic origins for nuclei (Poole & Penny, 2001). The various stages needed for endogenous membrane enfolding of the genome may be represented ‘frozen’ in different planctomycete genera. Planctomycetes form a ...
Eucalyptus Arabidopsis grandis thaliana
... SuSy amino acid residue determines its cellular distribution. In order to elucidate the role of SuSy in cellulose biosynthesis a number of questions surrounding the function and regulation of SuSy need to be addressed. These questions include: What is the nature of the association between SuSy and ...
... SuSy amino acid residue determines its cellular distribution. In order to elucidate the role of SuSy in cellulose biosynthesis a number of questions surrounding the function and regulation of SuSy need to be addressed. These questions include: What is the nature of the association between SuSy and ...
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... vegetal extracts tested present potential antimicrobial activity with efficient properties in the inhibition of Salmonella, especially vegetal extracts from the Myrtaceae family. ...
... vegetal extracts tested present potential antimicrobial activity with efficient properties in the inhibition of Salmonella, especially vegetal extracts from the Myrtaceae family. ...
Efficiency and Diversity of Protein Localization by Random Signal Sequences.
... efficiency of translocation that is indistinguishable from that of the wild-type invertase signal peptide (16). We were interested whether the function of these synthetic signal peptides could in some way be distinguished from that of the wild-type invertase signal peptide. One difference that has b ...
... efficiency of translocation that is indistinguishable from that of the wild-type invertase signal peptide (16). We were interested whether the function of these synthetic signal peptides could in some way be distinguished from that of the wild-type invertase signal peptide. One difference that has b ...
Modification-specific proteomics: Strategies for characterization of
... 3.2 Tagging PTMs by chemical derivatization A range of chemical methods has been developed to tag PTMs, including in vitro chemical reactions and in vivo metabolic labeling. Azide, due to its small size and bioorthogonal nature, has been used for metabolic labeling of PTMs. The resulting chemically ...
... 3.2 Tagging PTMs by chemical derivatization A range of chemical methods has been developed to tag PTMs, including in vitro chemical reactions and in vivo metabolic labeling. Azide, due to its small size and bioorthogonal nature, has been used for metabolic labeling of PTMs. The resulting chemically ...
Bactericidal, Bacteriolytic, and Antibacterial Virulence Activities of
... cell wall of S. mutans [11]. This present study revealed that treatment of S. pyogenes cells with B. pandurata extract resulted in cell lysis. A possible mechanism of action may be associated with cell wall and membrane damage. Proteases have long been considered as virulence factors for organisms a ...
... cell wall of S. mutans [11]. This present study revealed that treatment of S. pyogenes cells with B. pandurata extract resulted in cell lysis. A possible mechanism of action may be associated with cell wall and membrane damage. Proteases have long been considered as virulence factors for organisms a ...
PHOSPHOLIPIDS AND BIOMEMBRANES L. L. M. VAN DEENEN
... fragmented into elementary particles, 44 being the seat of enzymes from the electron-transfer chain and structural protein, 1s5 accounting for some 60 per cent of the total protein. The mitochondria is pictured by Green as a structural protein-phospholipid matrix to which are affixed many thousands ...
... fragmented into elementary particles, 44 being the seat of enzymes from the electron-transfer chain and structural protein, 1s5 accounting for some 60 per cent of the total protein. The mitochondria is pictured by Green as a structural protein-phospholipid matrix to which are affixed many thousands ...
high-throughput transient gene expression in plant
... create a well-less plant cell based microarray based on the viral vector/protoplast system for high-throughput analysis of multiple gene products in parallel. We proposed to entrap recombinant viral vectors harboring distinct cDNAs in hydrogel spotted at defined locations on the surface of a glass ...
... create a well-less plant cell based microarray based on the viral vector/protoplast system for high-throughput analysis of multiple gene products in parallel. We proposed to entrap recombinant viral vectors harboring distinct cDNAs in hydrogel spotted at defined locations on the surface of a glass ...