Keeping the immune system in check: a role for mitophagy
... Immunology and Cell Biology (2015) 93, 3–10; doi:10.1038/icb.2014.75; published online 30 September 2014 ...
... Immunology and Cell Biology (2015) 93, 3–10; doi:10.1038/icb.2014.75; published online 30 September 2014 ...
Here - Events
... each cell division cycle, independent of their volume at birth. This process, similar to what was recently observed in bacteria (1) enables the progressive reduction of errors in volume segregation. In one other cell type, Raji cells, the homeostasis mechanism appears less efficient and the amount o ...
... each cell division cycle, independent of their volume at birth. This process, similar to what was recently observed in bacteria (1) enables the progressive reduction of errors in volume segregation. In one other cell type, Raji cells, the homeostasis mechanism appears less efficient and the amount o ...
On the origin, evolution, and nature of programmed cell
... repressors (Bcl-2/Bcl-XL . . . ) and their antagonists (Bax/ Bak/Bid . . . ) share the capacity to homodimerize and to neutralize each others through heterodimerization, and, for some of them, to insert through a carboxyterminal hydrophobic transmembrane domain into the outer membrane of intracellul ...
... repressors (Bcl-2/Bcl-XL . . . ) and their antagonists (Bax/ Bak/Bid . . . ) share the capacity to homodimerize and to neutralize each others through heterodimerization, and, for some of them, to insert through a carboxyterminal hydrophobic transmembrane domain into the outer membrane of intracellul ...
Dendritic amplification of inhibitory postsynaptic potentials in a
... Information processing in the brain, as we understand it, is built upon the single-neuron input ⁄ output function (Koch & Segev, 2000). The neuronal output, the action potential, results from the integration of currents in the soma and initial axon segment. The input accesses the neuron primarily in ...
... Information processing in the brain, as we understand it, is built upon the single-neuron input ⁄ output function (Koch & Segev, 2000). The neuronal output, the action potential, results from the integration of currents in the soma and initial axon segment. The input accesses the neuron primarily in ...
a8d8a08cf7cae2b
... Human prostate gland Show end secretory parts of main of prostatic gland Strom composed from smooth muscle cells and c.t Prostatic concentration in the end secrtory parts of gland Stain : h&e ...
... Human prostate gland Show end secretory parts of main of prostatic gland Strom composed from smooth muscle cells and c.t Prostatic concentration in the end secrtory parts of gland Stain : h&e ...
Dual Location of the Mitochondrial Preprotein
... distinct forms of TIM17:23 have been identified, TIM17:23sort and TIM17:23motor (Schmidt et al., 2010). TIM17:23sort contains Tim17, 23, 50, and 21 and is involved in the lateral insertion of preproteins into the inner membrane (Schmidt et al., 2010). TIM17:23motor translocates proteins into the matr ...
... distinct forms of TIM17:23 have been identified, TIM17:23sort and TIM17:23motor (Schmidt et al., 2010). TIM17:23sort contains Tim17, 23, 50, and 21 and is involved in the lateral insertion of preproteins into the inner membrane (Schmidt et al., 2010). TIM17:23motor translocates proteins into the matr ...
Is ATP a Signaling Agent in Plants?
... eATP effects on plants were largely being interpreted in terms of supplementation of cellular energy or chelation of divalent cations rather than signaling activity. Plant mechanical movements (e.g. Jaffe, 1973), K⫹ uptake (e.g. Lüttge et al., 1974), and endonuclease activity (Udvardy and Farkas, 1 ...
... eATP effects on plants were largely being interpreted in terms of supplementation of cellular energy or chelation of divalent cations rather than signaling activity. Plant mechanical movements (e.g. Jaffe, 1973), K⫹ uptake (e.g. Lüttge et al., 1974), and endonuclease activity (Udvardy and Farkas, 1 ...
PDF + SI - Development - The Company of Biologists
... Cell wall weakening and subsequent cell rupture due to the behaviour of neighbouring cells may be a common feature involved in sensitizing or conditioning plant cells for dPCD during cell elimination. For example the death in the lateral root cap (lrc) cells is preceded by cell extension driven by t ...
... Cell wall weakening and subsequent cell rupture due to the behaviour of neighbouring cells may be a common feature involved in sensitizing or conditioning plant cells for dPCD during cell elimination. For example the death in the lateral root cap (lrc) cells is preceded by cell extension driven by t ...
Review Hepatitis C Virus RNA Replication and Assembly: Cell Host & Microbe
... resulting from multiple interactions between the fingers and thumb subdomains, and from structural movements of the linker and a b hairpin of the thumb subdomain that protrudes into the active site (Lesburg et al., 1999). This structure represents the so-called ‘‘closed’’ conformation of the polymer ...
... resulting from multiple interactions between the fingers and thumb subdomains, and from structural movements of the linker and a b hairpin of the thumb subdomain that protrudes into the active site (Lesburg et al., 1999). This structure represents the so-called ‘‘closed’’ conformation of the polymer ...
Regulatory roles of cyclin dependent kinase phosphorylation in cell
... [1]. Active, T161-phosphorylated and cyclin-bound Cdk can be inhibited by phosphorylation of two conserved residues within the catalytic cleft (residues Tyrl5 [Y15] and T h r l 4 [T14] in human Cdc2; see Fig. 1). Although these regulatory phosphorylations were identified on, and are best characteriz ...
... [1]. Active, T161-phosphorylated and cyclin-bound Cdk can be inhibited by phosphorylation of two conserved residues within the catalytic cleft (residues Tyrl5 [Y15] and T h r l 4 [T14] in human Cdc2; see Fig. 1). Although these regulatory phosphorylations were identified on, and are best characteriz ...
Misregulation of autophagy and protein degradation systems in
... AVMs are a group of lysosomal storage diseases primarily affecting cardiac and/or skeletal muscle. Pompe disease (or GSD II) is owing to a defect in lysosomal GAA enzyme (Raben et al., 2002), Danon disease (or GSD IIb) is caused by the lack of LAMP2 (Nishino et al., 2000), and Xlinked myopathy with ...
... AVMs are a group of lysosomal storage diseases primarily affecting cardiac and/or skeletal muscle. Pompe disease (or GSD II) is owing to a defect in lysosomal GAA enzyme (Raben et al., 2002), Danon disease (or GSD IIb) is caused by the lack of LAMP2 (Nishino et al., 2000), and Xlinked myopathy with ...
all-unit-learning-objectives
... Synthesis and Release of Proteins Explain how the amino acid sequence can affect function and structure in proteins. Describe the 2 groups in which proteins are classified according to their function Describe the structure and function of DNA Describe the process of DNA replication and explain ...
... Synthesis and Release of Proteins Explain how the amino acid sequence can affect function and structure in proteins. Describe the 2 groups in which proteins are classified according to their function Describe the structure and function of DNA Describe the process of DNA replication and explain ...
Regulatory Mechanisms for Specification and Patterning of Plant
... (TF), LONESOME HIGHWAY, is a potential regulator of this vascular patterning ...
... (TF), LONESOME HIGHWAY, is a potential regulator of this vascular patterning ...
Expression of GFP-fusions in Arabidopsis companion cells reveals
... non-invasive imaging (Oparka et al., 1994). Immunohistochemical studies (Stadler and Sauer, 1996) and GUS-histochemical analyses of AtSUC2-promoter::GUS plants had previously shown that the AtSUC2-promoter is active in the root phloem (Truernit and Sauer, 1995). Moreover, analyses of roots from AtSU ...
... non-invasive imaging (Oparka et al., 1994). Immunohistochemical studies (Stadler and Sauer, 1996) and GUS-histochemical analyses of AtSUC2-promoter::GUS plants had previously shown that the AtSUC2-promoter is active in the root phloem (Truernit and Sauer, 1995). Moreover, analyses of roots from AtSU ...
Keystone Standards
... BIO.A.4. 1. Identify and describe the cell structures involved in transport of materials into, out of, and throughout a cell. BIO.A.4. 1.1. Describe how the structure of the plasma membrane allows it to function as a regulatory structure and/or protective barrier for a cell. BIO.A.4. 1.2. Compare th ...
... BIO.A.4. 1. Identify and describe the cell structures involved in transport of materials into, out of, and throughout a cell. BIO.A.4. 1.1. Describe how the structure of the plasma membrane allows it to function as a regulatory structure and/or protective barrier for a cell. BIO.A.4. 1.2. Compare th ...
Functional analysis of the human CDC5L complex
... Nuclear pre-mRNA splicing is the process by which the introns (intervening sequences) in the primary transcript are speci®cally removed and the coding sequences joined to form mature mRNA, which is subsequently transported into the cytoplasm for protein synthesis. Splicing takes place in the nucleus ...
... Nuclear pre-mRNA splicing is the process by which the introns (intervening sequences) in the primary transcript are speci®cally removed and the coding sequences joined to form mature mRNA, which is subsequently transported into the cytoplasm for protein synthesis. Splicing takes place in the nucleus ...
Increased Association Between Rough Endoplasmic Reticulum
... domain and reduces its binding to microtubules (20). In JNPL3 mice, hyperphosphorylated tau accumulates in the somatodendritic compartment and forms NFTs in the motor neurons of the spinal cord, whereas neurons at the preYtangle stage predominate in the brain (19). The accumulation of tau protein in ...
... domain and reduces its binding to microtubules (20). In JNPL3 mice, hyperphosphorylated tau accumulates in the somatodendritic compartment and forms NFTs in the motor neurons of the spinal cord, whereas neurons at the preYtangle stage predominate in the brain (19). The accumulation of tau protein in ...
Mercury, Cadmium, and Arsenite Enhance Heat Shock Protein
... Fig. 1. A: Dose-dependent changes in de novo stress protein synthesis induced in chick embryos exposed to metals. Representative SDSPAGE (12.5% minigels) profiles of 35S-methionine-labeled chick embryonic proteins 2 h after exposure to 0 (Con), 3, 10, 30, or 100 nmol/ embryo of arsenite (As), cadmiu ...
... Fig. 1. A: Dose-dependent changes in de novo stress protein synthesis induced in chick embryos exposed to metals. Representative SDSPAGE (12.5% minigels) profiles of 35S-methionine-labeled chick embryonic proteins 2 h after exposure to 0 (Con), 3, 10, 30, or 100 nmol/ embryo of arsenite (As), cadmiu ...
Structural insights into the coupling of virion assembly and rotavirus
... Viruses perform numerous tasks during their replication cycles — from entry into the host cell, to viral protein production and genome replication, to the assembly and egress of nascent particles. Yet, for many viruses, it is not entirely clear how each stage of the replication cycle is controlled s ...
... Viruses perform numerous tasks during their replication cycles — from entry into the host cell, to viral protein production and genome replication, to the assembly and egress of nascent particles. Yet, for many viruses, it is not entirely clear how each stage of the replication cycle is controlled s ...
Integrated Microfluidic Nucleic Acid Isolation, Isothermal
... tens of targets suffices. This can be accomplished, for example, by incorporating multiple amplification reactors on a single chip, each containing primers for a specific target. The sample lysate is split and loaded on the several membrane/chamber channels, which can be imaged together using a CCD ...
... tens of targets suffices. This can be accomplished, for example, by incorporating multiple amplification reactors on a single chip, each containing primers for a specific target. The sample lysate is split and loaded on the several membrane/chamber channels, which can be imaged together using a CCD ...
Xyloglucan and its Interactions with Other Components of the
... which were intermingled with a gelled interface of acidic polysaccharides and structural protein; Thompson (2005) suggested that wall extensibility is controlled by spatial constraints in the movement of microfibrils rather than by direct interfibril linkages. These authors noted important shortcomi ...
... which were intermingled with a gelled interface of acidic polysaccharides and structural protein; Thompson (2005) suggested that wall extensibility is controlled by spatial constraints in the movement of microfibrils rather than by direct interfibril linkages. These authors noted important shortcomi ...
Regulation of the subcellular distribution of key cellular RNA
... Alternative splicing and polyadenylation of human cytomegalovirus (HCMV) immediate-early (IE) pre-mRNAs are temporally regulated and rely on cellular RNA-processing factors. This study examined the location and abundance of essential RNA-processing factors, which affect alternative processing of UL3 ...
... Alternative splicing and polyadenylation of human cytomegalovirus (HCMV) immediate-early (IE) pre-mRNAs are temporally regulated and rely on cellular RNA-processing factors. This study examined the location and abundance of essential RNA-processing factors, which affect alternative processing of UL3 ...
Glycolytic Enzymes Associate Dynamically with
... addition of KCN, an inhibitor of complex IV of the mitochondrial respiratory chain (Villani and Attardi, 2007), or increased by the addition of carbonyl cyanide m-chlorophenylhydrazone (CCCP), a proton ionophore that uncouples mitochondrial electron transport from ATP synthesis (Felle and Bentrup, 1 ...
... addition of KCN, an inhibitor of complex IV of the mitochondrial respiratory chain (Villani and Attardi, 2007), or increased by the addition of carbonyl cyanide m-chlorophenylhydrazone (CCCP), a proton ionophore that uncouples mitochondrial electron transport from ATP synthesis (Felle and Bentrup, 1 ...