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A Novel Form of DAP5 Protein Accumulates in Apoptotic Cells as a
A Novel Form of DAP5 Protein Accumulates in Apoptotic Cells as a

... hand and the rescue of the gene as a mediator of apoptosis on the other hand suggest that further studies of this gene should highlight novel mechanisms linking translational control to restriction of cellular outgrowth by PCD (21). While DAP5 was reported to be ubiquitously and abundantly expressed ...
Lecithin - Your Resource Center
Lecithin - Your Resource Center

... • is a B vitamin that supports brain, liver, cardiovascular and reproductive health • is involved in the absorption of fats into the cells (so you can use your fat soluble vitamins ... A, D, and E) • plays an important role in passing signals from one nerve to the other … example: as soon as you tou ...
Interaction of Antiparallel Microtubules in the
Interaction of Antiparallel Microtubules in the

... spindle (Zhang et al., 1990). Whereas the overall organization of phragmoplast MTs is well appreciated, the method by which they are organized into such an elegant array while remaining highly dynamic remains unknown. In Haemanthus endosperm cells, short cross-bridges were detected between antiparal ...
Immune Escape of Human Papillomavirus Type 16 in A Major Role
Immune Escape of Human Papillomavirus Type 16 in A Major Role

... We sought to determine whether L2 is responsible for initiating immune escape of HPV16 in LC. First, to verify the purity of the LC used in this study, we assessed by flow cytometry the presence of surface markers commonly used to identify LC: langerin, CD1a, and E-cadherin. Our results show that LC ...
Pretreatment Increases Cytokine-induced NO Production
Pretreatment Increases Cytokine-induced NO Production

... iNOS antibody was obtained from Transduction Laboratories (Lexington, KY). SNAP and oxidized SNAP were prepared as described previously (19, 20). Red blood cells were prepared by collecting blood from rats as previously described (21). Antibodies for GTPCHI and GFRP were generated by Dr. Kazuyuki Ha ...
abscisic acid signal transduction
abscisic acid signal transduction

... The scientific origins of abscisic acid (ABA) have been traced to several independent investigations in the late 1940s, but it was only in the 1960s that ABA was isolated and identified (1). Mutants affected in ABA biosynthesis are known in a variety of plant species (39, 146). The characterization ...
Blood Groups
Blood Groups

... Structural characteristics contribute to its gas transport function ...
A B23-interacting sequence as a tool to visualize protein interactions
A B23-interacting sequence as a tool to visualize protein interactions

... mobility of proteins would ensure their diffusion and availability throughout the nucleus. In nuclear bodies the mobility of proteins is reduced most probably by interactions with partners. This determines a residence time based on affinities and functions of the proteins (Chen and Huang, 2001; Dund ...
Fuller`s Earth - American Chemical Society
Fuller`s Earth - American Chemical Society

... 4. Why might graphene be a preferable choice for touch screens in phones and computer screens? Touch screens must be conductive. It would also be good to have both thin and flexible screens. Graphene provides all these properties. Currently screens have a conductive layer of indium tin oxide which i ...
Collagen in the Human Lung
Collagen in the Human Lung

... Received for publication 15 August 1974 and in revised form 12 Necvmber 1974. ...
File
File

... In the space below, write a short essay that first identifies the connective cell types discussed in your text. Next, distinguish these cell types from each other by their physical characteristics and by the type of matrix in which the cells are embedded. Finally, relate the physical characteristics ...
The Mid-Missouri Area Health Education Center Science Resource
The Mid-Missouri Area Health Education Center Science Resource

... The Mid-Missouri Area Health Education Center Science Resource Library was created to provide resources for educators and students in rural and underserved areas of the 23 counties we serve who might not otherwise have access to quality science and health materials. Refer to the map on the back cove ...
Cell-Mediated Crystallization of Calcium Oxalate in
Cell-Mediated Crystallization of Calcium Oxalate in

... Pautard, 1970; Horner and Wagner, 1995). Mucilage, consisting mainly of complex polysaccharides, also may accumulate within such vacuoles, particularly in association with raphides (Kausch and Horner, 1984; Wang et al., 1994; Webb et al., 1995). In certain plants, paracrystalline bodies (Horner and ...
Spiralian Development: A Perspective Seventy
Spiralian Development: A Perspective Seventy

... There was the general idea that a primitive coelomate ancestor, with spiral cleavage of the quartet type, gave rise to a turbellarian archetype, from which higher forms were evolved. This was discussed as early as 1914 by Heider, although we do not find the term "Spiralia" in Heider's paper. Heider' ...
chloroquine inhibits lysosomal enzyme pinocytosis and enhances
chloroquine inhibits lysosomal enzyme pinocytosis and enhances

... (20) found no evidence that previously internalized a-iduronidase was lost on exposure to chloroquine, and inferred from the kinetics of inhibition of enzyme pinocytosis that amines do not block cell surface binding . However, they confirmed the inhibition of enzyme pinocytosis and suggested that so ...
Presentation, Diagnosis and Management of Mast Cell Activation
Presentation, Diagnosis and Management of Mast Cell Activation

... in this region seem to cause constitutive activation of the KIT protein. Thus, binding of ligand (stem cell factor) is no longer needed to activate the multiple pathways downstream from KIT which can result in reproduction, anti-apoptosis (which has turned out to be the dominant manner of mast cell ...
237-747-1-SP - International Journal of Applied Research in
237-747-1-SP - International Journal of Applied Research in

... colocynthis; 90 ml of 5.0 mM aqueous solution of silver nitrate (Sigma Aldrich, Egypt) were added to 10 ml of stock solutions, and kept at room temperature for 24 hours. SNPs in the AE extracts were recognized by the color change to reddish brown and by TEM analysis. For TEM analysis a drop of the ...
Formation and excretion of autophagic plastids (plastolysomes) in
Formation and excretion of autophagic plastids (plastolysomes) in

... The change in developmental fate of microspores reprogrammed toward embryogenesis is a complex but fascinating experimental system where microspores undergo dramatic changes derived from the developmental switch. After 40 years of study of the ultrastructural changes undergone by the induced microsp ...
LMA® Gastro™ Cuff Pilot - Teleflex | LMA
LMA® Gastro™ Cuff Pilot - Teleflex | LMA

... pressure. Diffusion rate and resulting peak pressure may vary with the initial volume of air injected into the cuff, the type of gases used to inflate the cuff, and the percentage of nitrous oxide in the inhaled mixture. • The intra-cuff pressure may rise slightly after the endoscope has been inser ...
How autophagy both activates and inhibits cellular
How autophagy both activates and inhibits cellular

... roles of autophagy in cellular homeostasis. Is there a molecular mechanism that could resolve these apparently conflicting reports about the relationship between autophagy and cellular senescence? One potential explanation is that autophagy may modulate several targets that act in an opposite manner ...
Gene Section AURKB (aurora kinase B) Atlas of Genetics and Cytogenetics
Gene Section AURKB (aurora kinase B) Atlas of Genetics and Cytogenetics

... In mitosis, the chromosomal passenger complex, composed of Aurora B, Survivin, Borealin and INCENP, controls chromosome alignment, histone modification, and cytokinesis (Knauer et al., 2007). Presence of this complex at the right place at the right time is the key to precise control of its enzymatic ...
Novel Mechanism of PTEN Regulation by Its
Novel Mechanism of PTEN Regulation by Its

... Cells sense external chemical gradients and respond by moving toward the higher concentration of chemoattractant. Chemotaxis is important for a wide variety of physiological and pathological events such as axon guidance, immune response, wound healing, tissue morphogenesis, and carcinoma invasion. T ...
USING ADENOSINE TRIPHOSPHATE (ATP) AS A SUBSTITUTE APPLICATIONS
USING ADENOSINE TRIPHOSPHATE (ATP) AS A SUBSTITUTE APPLICATIONS

... Osteoarthritis is the end result of damage to articular cartilage, which lacks the ability to self-repair. Tissue engineering of cartilage is a promising field of study that aims to promote healing of cartilage in vivo by manipulation of the chondrocytes that maintain the tissue, or through in vitro ...
catecholamine-depleted rat ventricular myocytes
catecholamine-depleted rat ventricular myocytes

... potential duration. Ito amplitude is regulated by ␣1agonists in rat ventricular myocytes (2, 4) and by ␤-adrenergic agonists in canine Purkinje fibers (27). Both effects inducing a decrease in Ito are modulated by phosphorylation. A marked decrease in Ito density has been reported in various cardiac ...
Fungi represent a group of heterotrophic living organisms which are
Fungi represent a group of heterotrophic living organisms which are

... types fuse to form a diploid nucleus. This is followed immediately by meiosis, during which synapsis and crossing over takes place. As a result of this, + and – types of spores are produced that have recombination of alleles. The spores, numbering millions, blow away, and each germinates into a new ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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