The glycocalyx of the sperm surface
... it must be equipped with selective mechanisms to bind and penetrate the zona pellucida. It then has to fuse with and traverse the oocyte plasmalemma and undergo nuclear decondensation and zygote formation. Additionally, it has to be resilient to the immune defence mechanisms of the female tract, yet ...
... it must be equipped with selective mechanisms to bind and penetrate the zona pellucida. It then has to fuse with and traverse the oocyte plasmalemma and undergo nuclear decondensation and zygote formation. Additionally, it has to be resilient to the immune defence mechanisms of the female tract, yet ...
Microbiology Focus 6.1 - The Role of - Sigma
... cells are embedded in extracellular matrices composed of proteins, sugars, and extracellular DNA.7, 8 If progress is going to be made in treatment and restoration of patient health, it is also necessary to gain a better understanding of what occurs between the immune system’s cells and MRSA biofilms ...
... cells are embedded in extracellular matrices composed of proteins, sugars, and extracellular DNA.7, 8 If progress is going to be made in treatment and restoration of patient health, it is also necessary to gain a better understanding of what occurs between the immune system’s cells and MRSA biofilms ...
1 Calcium at the Cell Wall
... A second argument against the idea that the bulk of the Ca2+ detected from the influx data directly crosses the PM and enters the cytoplast stems from the lack of agreement in the phase relationships. Thus the increase in the intracellular tip-focused gradient increases +10-400 behind the increase i ...
... A second argument against the idea that the bulk of the Ca2+ detected from the influx data directly crosses the PM and enters the cytoplast stems from the lack of agreement in the phase relationships. Thus the increase in the intracellular tip-focused gradient increases +10-400 behind the increase i ...
Multiple classes of yeast mutants are defective in vacuole
... complementation groups (VAC8-VAC12). Unlike mutants identified previously, three of the complementation groups exhibit normal vacuolar morphology. Zygote studies revealed that these vac mutants are also defective in intervacuole communication. Although at least four pathways of protein delivery to t ...
... complementation groups (VAC8-VAC12). Unlike mutants identified previously, three of the complementation groups exhibit normal vacuolar morphology. Zygote studies revealed that these vac mutants are also defective in intervacuole communication. Although at least four pathways of protein delivery to t ...
15 Respiration
... The lungs, like the heart, are situated in the thorax, the compartment of the body between the neck and abdomen. “Thorax” and “chest” are synonyms. The thorax is a closed compartment that is bounded at the neck by muscles and connective tissue and completely separated from the abdomen by a large, do ...
... The lungs, like the heart, are situated in the thorax, the compartment of the body between the neck and abdomen. “Thorax” and “chest” are synonyms. The thorax is a closed compartment that is bounded at the neck by muscles and connective tissue and completely separated from the abdomen by a large, do ...
NIH Public Access - Khademhosseini Lab
... a plethora of new approaches to design customized nanocomposite hydrogels are emerging (Schexnailder and Schmidt, 2009; Cha et al., 2013; Goenka et al., 2014). Due to their high electrical conductivity, nanocomposites reinforced with CNTs can be used to engineer a range of electrically conductive ti ...
... a plethora of new approaches to design customized nanocomposite hydrogels are emerging (Schexnailder and Schmidt, 2009; Cha et al., 2013; Goenka et al., 2014). Due to their high electrical conductivity, nanocomposites reinforced with CNTs can be used to engineer a range of electrically conductive ti ...
Analysis of the tendon cell fate - Development
... expressed at low levels in the intersomitic mesenchyme, while high levels of expression and early cartilage condensations are found only in the body of the somite at this stage (Fig. 3C). It appears, therefore, that the scleraxis-expressing cells are a distinct population of cells aligned in relatio ...
... expressed at low levels in the intersomitic mesenchyme, while high levels of expression and early cartilage condensations are found only in the body of the somite at this stage (Fig. 3C). It appears, therefore, that the scleraxis-expressing cells are a distinct population of cells aligned in relatio ...
Click on the button to this PDF research
... induced a decrease in the production of H2O2 and TNF-α at 20 and 40% concentrations when compared to the control RPMI. However, when compared with this medicine excipient, a significant decrease in these mediators was observed with Canova® at 40% concentration only. The production of NO and phagocyt ...
... induced a decrease in the production of H2O2 and TNF-α at 20 and 40% concentrations when compared to the control RPMI. However, when compared with this medicine excipient, a significant decrease in these mediators was observed with Canova® at 40% concentration only. The production of NO and phagocyt ...
Stomatal Size, Speed, and Responsiveness
... physiological drivers, gs is also dependent upon anatomical characteristics. Stomatal anatomical features define the maximum theoretical conductance (Dow et al., 2014a) and also influence the speed of response. Maximum gs is dictated by the size and density of stomata, which in turn can be influenced b ...
... physiological drivers, gs is also dependent upon anatomical characteristics. Stomatal anatomical features define the maximum theoretical conductance (Dow et al., 2014a) and also influence the speed of response. Maximum gs is dictated by the size and density of stomata, which in turn can be influenced b ...
Development of in vitro procedures that can predict the safety of
... pre-clinical safety tests that can better predict the toxicity of immunomodulatory mAbs, such as TGN1412, are required. The aim of this study was to investigate the hypothesis that cytokinedriven adverse effects of therapeutic monoclonal antibodies and the mechanisms involved can be better predicted ...
... pre-clinical safety tests that can better predict the toxicity of immunomodulatory mAbs, such as TGN1412, are required. The aim of this study was to investigate the hypothesis that cytokinedriven adverse effects of therapeutic monoclonal antibodies and the mechanisms involved can be better predicted ...
Department of Developmental and Cell Biology
... The Developmental and Cell Biology major is intended to provide students with intensive training in cutting edge approaches to understanding the structure and function of cells and how they interact to produce a complex organism, starting with a fertilized egg. The focus of the B.S. in Developmental ...
... The Developmental and Cell Biology major is intended to provide students with intensive training in cutting edge approaches to understanding the structure and function of cells and how they interact to produce a complex organism, starting with a fertilized egg. The focus of the B.S. in Developmental ...
SYNTHETIC PEPTIDES AS ANTIGENS AND COMPETITORS IN
... recognize antigens in association with class I MHC molecules, whereas helper T cells are class II restricted . The molecular details of the presumed interaction between MHC molecules, antigen, and antigen-specific T cell receptors have not yet been elucidated . In class II-restricted systems, the ch ...
... recognize antigens in association with class I MHC molecules, whereas helper T cells are class II restricted . The molecular details of the presumed interaction between MHC molecules, antigen, and antigen-specific T cell receptors have not yet been elucidated . In class II-restricted systems, the ch ...
Characterization of Vincristine Transport by the Mr 190,000
... lished. Net ATP/GSH-dependent [3H]VCR uptake in H69AR mem brane vesicles increased with increasing concentrations of VCR up to 1.2 /tM (the highest concentration tested), to reach approximately 70 pmol/mg (Fig. 2/t). Similarly, as the GSH concentration was increased from 1 to 5 mM, ATP-dependent [3H ...
... lished. Net ATP/GSH-dependent [3H]VCR uptake in H69AR mem brane vesicles increased with increasing concentrations of VCR up to 1.2 /tM (the highest concentration tested), to reach approximately 70 pmol/mg (Fig. 2/t). Similarly, as the GSH concentration was increased from 1 to 5 mM, ATP-dependent [3H ...
Isolation and biological activity of extracellular slime associated with
... Essentially nothing is known about the ...
... Essentially nothing is known about the ...
UK Stem Cell Strategic Forum Annex
... from unrelated donor HSCT has grown significantly in recent years, with 749 transplants performed in 2009. Patient outcomes following HSCT using unrelated donor stem cells are improving, with 1-year survival rates for transplanted patients at 54% between 2002 and 2006, compared to 42% between 1996 a ...
... from unrelated donor HSCT has grown significantly in recent years, with 749 transplants performed in 2009. Patient outcomes following HSCT using unrelated donor stem cells are improving, with 1-year survival rates for transplanted patients at 54% between 2002 and 2006, compared to 42% between 1996 a ...
a va i l a b l e a t... w w w. e l s e v i e...
... constitutively in most cells and tissues, it is unclear how ligand activity could change in response to the need to modulate Notch signals. Delta proteins also undergo proteolysis, which separates the Notch-binding extracellular domain from the cytosolic domain and endocytosis machinery [6,8]. As a ...
... constitutively in most cells and tissues, it is unclear how ligand activity could change in response to the need to modulate Notch signals. Delta proteins also undergo proteolysis, which separates the Notch-binding extracellular domain from the cytosolic domain and endocytosis machinery [6,8]. As a ...
Reactive oxygen species are linked to the toxicity of the
... Experimental cultures produced by Alexandrium spp. are responsible for the toxicity of these dinoflagellates to protists (TillThree strains in the Alexandrium tamarense spemann & John 2002, Fistarol et al. 2004). These cies complex (Table 1; hereafter referred to as harmful compounds are often refer ...
... Experimental cultures produced by Alexandrium spp. are responsible for the toxicity of these dinoflagellates to protists (TillThree strains in the Alexandrium tamarense spemann & John 2002, Fistarol et al. 2004). These cies complex (Table 1; hereafter referred to as harmful compounds are often refer ...
Characterization of the ATPase Activity of the Mr 170,000 to 180,000
... When tumor cells acquire resistance to naturally occurring anticancer drugs such as lïneualkaloids or anthracyclines, they generally show cross-resistance to other antitumor agents (1). Reduced intracellular drug accumulation resulting from in creased active drug efflux across plasma membranes is a ...
... When tumor cells acquire resistance to naturally occurring anticancer drugs such as lïneualkaloids or anthracyclines, they generally show cross-resistance to other antitumor agents (1). Reduced intracellular drug accumulation resulting from in creased active drug efflux across plasma membranes is a ...
casanova and endoderm formation - Development
... have been identified but it is now essential to understand how these genes, particularly cas, act within the Nodal signalling pathway to ensure proper endoderm development and differentiation. First, the precise position of cas in the genetic hierarchy controlling endoderm development and the mechan ...
... have been identified but it is now essential to understand how these genes, particularly cas, act within the Nodal signalling pathway to ensure proper endoderm development and differentiation. First, the precise position of cas in the genetic hierarchy controlling endoderm development and the mechan ...
The Wnt signaling pathway mechanisms
... tube as a result of local differentiation and proliferation of cardiomyocytes (de Jong et al., 1997; Christoffels et al., 2000; Christoffels et al., 2004). With development the heart tube increases in length by the addition of cardiomyocytes at both the arterial and venous poles of the heart tube ra ...
... tube as a result of local differentiation and proliferation of cardiomyocytes (de Jong et al., 1997; Christoffels et al., 2000; Christoffels et al., 2004). With development the heart tube increases in length by the addition of cardiomyocytes at both the arterial and venous poles of the heart tube ra ...
Immunoglobulin free light chains in inflammatory diseases
... and then the Ag-specific minority is activated in the tissues by Ag-MHC complexes on a few local antigen presenting cells, like dendritic cells. There, activated T cells produce various cytokines that induce the local tissue cells to produce chemokines that recruit a non-specific inflammatory cell i ...
... and then the Ag-specific minority is activated in the tissues by Ag-MHC complexes on a few local antigen presenting cells, like dendritic cells. There, activated T cells produce various cytokines that induce the local tissue cells to produce chemokines that recruit a non-specific inflammatory cell i ...
Chapter 13- Bones and Muscles
... The next largest unit of organization in your body is a tissue-a group of specialized cells that perform the same function. The human body contains four basic types of tissue. Look at Figure 2 as you read about each type. Like the muscle cells that form it, muscle tissue can contract, or shorten. By ...
... The next largest unit of organization in your body is a tissue-a group of specialized cells that perform the same function. The human body contains four basic types of tissue. Look at Figure 2 as you read about each type. Like the muscle cells that form it, muscle tissue can contract, or shorten. By ...
a cells- secrete glucagon
... Glucose is liberated from dietary carbohydrate such as starch or sucrose by hydrolysis within the SI, and is then absorbed into the blood. Elevated concentrations of glucose in blood stimulate release of insulin, and insulin acts on cells thoughout the body to stimulate uptake, utilization and stora ...
... Glucose is liberated from dietary carbohydrate such as starch or sucrose by hydrolysis within the SI, and is then absorbed into the blood. Elevated concentrations of glucose in blood stimulate release of insulin, and insulin acts on cells thoughout the body to stimulate uptake, utilization and stora ...
Study of Pseudomonas aeruginosa and different wound dressing
... matrix and a variety of cell mediators usually resulting in wound closure within days or weeks. In a non-healing, chronic wound the healing process has been disturbed and is often detained in an inflammatory phase, and is unable to progress into the next stage of cell proliferation. The most common ...
... matrix and a variety of cell mediators usually resulting in wound closure within days or weeks. In a non-healing, chronic wound the healing process has been disturbed and is often detained in an inflammatory phase, and is unable to progress into the next stage of cell proliferation. The most common ...
A Novel Form of DAP5 Protein Accumulates in Apoptotic Cells as a
... hand and the rescue of the gene as a mediator of apoptosis on the other hand suggest that further studies of this gene should highlight novel mechanisms linking translational control to restriction of cellular outgrowth by PCD (21). While DAP5 was reported to be ubiquitously and abundantly expressed ...
... hand and the rescue of the gene as a mediator of apoptosis on the other hand suggest that further studies of this gene should highlight novel mechanisms linking translational control to restriction of cellular outgrowth by PCD (21). While DAP5 was reported to be ubiquitously and abundantly expressed ...