• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
PDF
PDF

... C2C12 cells transfected with a Coco siRNA have a twofold higher rate of myoblast differentiation, as determined by myogenin immunostaining, compared with cells transfected with a control siRNA (Fig. 5A,B). Consistently, overexpression of Coco completely inhibited myoblast differentiation (Fig. 5A,B) ...
Influence of ovarian muscle contraction and oocyte growth on egg
Influence of ovarian muscle contraction and oocyte growth on egg

... introduce a role for ovarian muscles in egg chamber elongation. There are two muscle types in the ovary proper: (1) the epithelial sheath, a tube of muscle that surrounds each ovariole, and (2) the peritoneal sheath, a thin meshwork that surrounds the entire ovary (Hudson et al., 2008). We focus on ...
Cytoskeleton: What Does GTP Do for Septins? Dispatch
Cytoskeleton: What Does GTP Do for Septins? Dispatch

... complexes from cells and Drosophila embryos showed that each septin subunit indeed binds a molecule of guanine nucleotide [6,7]. For all GTPases, understanding their biochemistry has hinged on understanding the role of GTP binding and hydrolysis, and it seems likely that the same will hold for septi ...
Antibodies produced in vitro in the detection of periodontal bacteria
Antibodies produced in vitro in the detection of periodontal bacteria

... 1987). Several studies have also suggested that elevated serum antibody levels in patients with periodontitis, correlating to alveolar bone loss, are a key factor associated with coronary heart diseases (Pussinen et al., 2003). IgG titers have been used as a diagnostic tool as an indicator of immune ...
Four-cell stage mouse blastomeres have different developmental
Four-cell stage mouse blastomeres have different developmental

... different fates, the question arises as to whether they are equivalent to each other. This could happen, for example, as a consequence of their spatial relationship per se or because they inherit different properties when they divide. Indeed it has been proposed that an equatorial division of the tw ...
Biological Properties and Characterization of Lectin from Red
Biological Properties and Characterization of Lectin from Red

... Lectins bind carbohydrates reversibly and non-covalently, detecting subtle differences in their complex structure.(21) According to their carbohydrate specificity, they can broadly be divided into those that bind monosaccharides, as well as oligosaccharides and those that recognize oligosaccharides ...
Core Transcriptional Regulatory Circuit Controlled by the
Core Transcriptional Regulatory Circuit Controlled by the

... primagrafts (Prima 2 and Prima 5) and cell lines (CCRF-CEM and Jurkat) at the CD69, TCRA, and NKX3-1 loci. The x axis indicates the linear sequence of genomic DNA, and the y axis the total number of mapped reads. The black horizontal bar above each gene example indicates the genomic scale in kilobas ...
Location and Size of Dopaminergic and Serotonergic Cell
Location and Size of Dopaminergic and Serotonergic Cell

... nigra (SN), ventral tegmental area (VTA), and retrorubral field (RrF) project to the striatum, cortex, and nucleus accumbens (Björklund and Lindvall, 1984). They modulate a variety of functions, such as movement, rewarding, cognition, and feeding (Zhou and Palmiter, 1995; Cooper et al., 2001). A dy ...
The head organizer in Hydra
The head organizer in Hydra

... 2000; Broun et al., 2005). Subsequently, it was shown that six other Wnt genes (HyWnt1, HyWnt7, HyWnt9/10a, HyWnt9/10c, HyWnt11, HyWnt16) are expressed in the hypostome (Lengfeld et al., 2009). All are expressed only in the hypostome, although the extent of expression from the apex down to the base ...
SCF Class 5
SCF Class 5

... processed out through the kidney and urine. Very large amounts become like a chemical and need to be processed through the liver. This would cause a Reverse Effect, because they can get stuck in the liver. That means that they would cause problems, deficiency symptoms, in the same area of the body t ...
Role of Template Activating Factor-I as a
Role of Template Activating Factor-I as a

... separated by 10% SDS-PAGE and visualized with Coomassie Brilliant Blue staining. Lane M contains molecular size markers. (B) Formation of histone H1.1NCPs complexes was examined by nucleoprotein gel analyses. The 196 bp 5S rRNA gene fragments or NCPs (0.4 pmol of DNA) assembled on the same DNA with ...
Chloroplast structure: from chlorophyll granules to supra
Chloroplast structure: from chlorophyll granules to supra

... This review provides a brief historical account of how microscopical studies of chloroplasts have contributed to our current knowledge of the structural and functional organization of thylakoid membranes. It starts by tracing the origins of the terms plastid, grana, stroma and chloroplasts to light ...
here - KC Huang - Stanford University
here - KC Huang - Stanford University

... 53. T Fleming, E Becker, S Lee, JY Shin, KC Huang, C Bustamante, and K Pogliano, “SpoIIIE assembly mediates septal membrane fission during Bacillus subtilis sporulation,” Genes and Development 24 1160 (2010). 54. KC Huang, R Mukhopadhyay, B Wen, Z Gitai, and NS Wingreen, “Cell shape and cell-wall or ...
PDF
PDF

... facilitates the integration and processing of synaptic and sensory input. Although studies in Drosophila and vertebrate systems have identified a variety of factors that regulate dendrite branch formation, the molecular mechanisms that control this process remain poorly defined. Here, we introduce t ...
pH-Sensitive Core-Shell Nanoparticles for Intracellular Drug Delivery
pH-Sensitive Core-Shell Nanoparticles for Intracellular Drug Delivery

... efficiently. The applications of nanoparticles showed significant improvement in delivering a model antigen vaccine protein ovalbumin (OVA) to primary dendritic cells for T cell activation, and promising knockdown of mRNA by delivering siRNA to epithelial cells for gene silencing. To extend this app ...
Naturally Occurring Ligand Isoforms Receptor Binding and Function
Naturally Occurring Ligand Isoforms Receptor Binding and Function

... and murine flt3 ligands, respectively, whereas isoform-2 has a deletion within this domain. Bovine flt3 ligand isoform 1, but not 2, bound the human flt3 receptor and stimulated murine pro B cells transfected with the murine flt3 receptor. This retention of binding and function allowed definition of ...
Bioreactor landfills: experimental and field results
Bioreactor landfills: experimental and field results

... brought to field capacity (45% by volume) by adding tap water to the bioreactor cells daily, until the amount of leachate collected from the cell equaled the amount of water added the previous day. Leachate was recirculated three times a week for the first 6-month period, which corresponds to a volume ...
Dual Modes of Endoplasmic Reticulum-to
Dual Modes of Endoplasmic Reticulum-to

... or just late-stage post-Golgi vesicles contribute to dendritic secretory trafficking remains poorly understood. In this study, we have used live-cell confocal imaging experiments along with immunocytochemistry in cultured hippocampal neurons to define the secretory pathway in dendrites. We demonstra ...
Article Title Authors Author affiliation Correspondence information
Article Title Authors Author affiliation Correspondence information

... autophagic cell death mainly functions through JNK pathway [46]. Puissant, et al. reported that phytoalexin resveratrol (RSV) could induce autophagy in chronic myeloid leukemia (CML) through JNK-dependent p62 accumulation, as well as through over-expression of JNK-mediated p62 and AMPK activation [4 ...
LESSON 3 Your Circulatory and Respiratory Systems
LESSON 3 Your Circulatory and Respiratory Systems

... Air passes from the pharynx into a triangle-shaped area called the larynx. Two thick folds of tissue in the larynx—the vocal cords— vibrate and make sounds as air passes over them. The tissues of the larynx allow a person to speak. New Vocabulary larynx The upper part of the respiratory system, whic ...
AMPA Receptors Are Involved in Store-Operated Calcium
AMPA Receptors Are Involved in Store-Operated Calcium

... acetoxymethyl (AM) analysis of untreated neurons (control) and neurons treated with indicated antagonists. Measurements were started in a buffer with 2 mM CaCl2 , then in a buffer that contained 100 µM AMPA in the absence or presence indicated antagonists 100 µM ML-9 (A) 30 µM CNQX (B) 5 µM nimodipi ...
Myeloma and the kidney
Myeloma and the kidney

... mention any new symptoms to your doctor straight away. Patients with myeloma kidney disease can have no symptoms. This is because the body can tolerate even a large reduction in kidney function – for example, most people can remain healthy with only one functioning kidney. However, as kidney disease ...
Electro Lymphatic Therapy by Jennifer Johnson, ND, CLT
Electro Lymphatic Therapy by Jennifer Johnson, ND, CLT

... reasonable, to good job of opening the surface lymphatic using a therapeutic technique known as manual lymph drainage developed in Europe 25 years ago. Through delicate massaging techniques it was highly effective at reducing lymph-based disorders, but the process is very labor intensive The tradeof ...
A guide to studying human hair follicle cycling in vivo
A guide to studying human hair follicle cycling in vivo

... between xenografted and freshly biopsied human scalp HFs is needed. Because such a comparison has previously been unavailable, there is limited understanding of the extent to which human hair cycle events seen in host mice are representative of normal human hair cycle ...
The glycocalyx of the sperm surface
The glycocalyx of the sperm surface

... it must be equipped with selective mechanisms to bind and penetrate the zona pellucida. It then has to fuse with and traverse the oocyte plasmalemma and undergo nuclear decondensation and zygote formation. Additionally, it has to be resilient to the immune defence mechanisms of the female tract, yet ...
< 1 ... 22 23 24 25 26 27 28 29 30 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report