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Species-Specific Activity of SIV Nef and HIV-1 Vpu
Species-Specific Activity of SIV Nef and HIV-1 Vpu

... 293T cells were selected for these assays since previous studies have shown that these cells do not express endogenous tetherin in the absence of IFNa induction [1,11]. Virus release was measured by HIV-1 p24 and SIV p27 antigen-capture ELISA at 0, 2, 20 and 200 ng of plasmid DNA for each tetherin e ...
CHAPTER 2 Literature Review I   Bone Homeostasis
CHAPTER 2 Literature Review I Bone Homeostasis

... receptor (RXR), as shown. (Kersten S, Desvergne B, Wahli W. Roles of PPARs in health and disease. Nature 2000;405:421-4). ...
CELLS - Hudson City School District
CELLS - Hudson City School District

...  helps it maintain its shape  Outside the cell membrane ...
Dishevelled: at the crossroads of divergent
Dishevelled: at the crossroads of divergent

... signaling factors cannot always be distinguished by their properties in vitro assays, the outcome of the signaling events in vivo is often very speci®c. Signaling molecules of the Wnt family are representative examples. Seven-pass transmembrane receptors of the Frizzled (Fz) family have recently bee ...
Structural Levels of Organization
Structural Levels of Organization

... • Movement of material across the membrane of a cell by means of a chemical activity that allows the cell to admit larger molecules than would otherwise be able to enter • Requires energy ...
Chato, a KRAB zinc-finger protein, regulates
Chato, a KRAB zinc-finger protein, regulates

... rearrangements that lead to convergent extension during early somite stages, and that these cell rearrangements fail in chato embryos. Although non-canonical Wnt signaling is important for convergent extension in the mouse notochord and neural plate, the results indicate that chato regulates body ax ...
The Crucial Role of Biofilms in Cryptococcus neoformans Survival
The Crucial Role of Biofilms in Cryptococcus neoformans Survival

... GXM polymers likely leading to increased capsular rigidity and thus mechanically blocking the release of GXM, perhaps even GXM-containing vesicles [33,34]. In contrast, GXM-specific IgG1 18B7 co-administered with antifungal agents showed decreased pharmacological efficacy against cryptococcal biofil ...
Responses of plant vascular systems to auxin transport
Responses of plant vascular systems to auxin transport

... One peculiarity of vascular tissue induction by IAA is that it occurs in a linear manner: locally applied IAA induces a new vascular strand extending basally from the site of application (Sachs, 1991). The observation is intriguing in three respects: first, the differentiation occurs along a narrow ...
Section II
Section II

... (E). Very low level of Factor IX Q 22. One of the following features is specific for Christmas Disease: (A). Very low level of Factor VIII:c (B). Very low level of von Willebrand Factor (C). Prolonged Bleeding Time (D). Severe thrombocytopenia (E) Very low level of Factor IX Q 23. One of the followi ...
Platelets Served with - The Journal of Immunology
Platelets Served with - The Journal of Immunology

... known to be involved in acute and chronic liver disease related to hepatitis B virus infection via upregulation of virusspecific CD8+ T cells and nonspecific inflammatory cells into the liver (17). Furthermore, platelets were implicated in the clearance of bacterial infections: thrombin-stimulated p ...
ch1
ch1

... Answer: right upper quadrant (RUQ): right lobe of liver, gallbladder, right kidney, portions of stomach, large and small intestines; left upper quadrant (LUQ): left lobe of liver, stomach, pancreas, left kidney, spleen, portions of large intestine Diff: 1 ...
Assembly of RecA-like Recombinases
Assembly of RecA-like Recombinases

... divided into two broad classes: those that act before homology search by promoting assembly of recombinase filaments, and those that act during homology search and strand exchange. Assembly factors can, in turn, be divided into two classes: ssDNA-binding protein (ssb) and assembly ‘‘mediators.’’ Her ...
Polymeric nanoreactors for use in enzyme replacement therapy
Polymeric nanoreactors for use in enzyme replacement therapy

... A lot of known genetic deficiencies in human are caused by a mutation of a crucial enzyme, leading to the accumulation of one or more of its substrates. As a result toxic concentrations of the substrates appear in the bloodstream and tissues and disturb the normal metabolic degradation pathways. Enz ...
Par3/Baz levels control epithelial folding at actomyosin
Par3/Baz levels control epithelial folding at actomyosin

... generated ectopic parasegment boundaries by expressing wingless in the whole epithelium (armGal4/UAS-wg, hereafter arm>wg) (Sanson et al., 1999; Larsen et al., 2008). In these embryos, Engrailed expression expands posteriorly to fill its competence domain and an ectopic boundary forms at the posteri ...
Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as
Endoplasmic Reticulum Export Sites and Golgi Bodies Behave as

... ER-to-Golgi protein transport may occur in plants. It was proposed that Golgi bodies move between fixed ERES in an actinmyosin–dependent fashion (stop-and-go model; Nebenführ et al., 1999). This model suggests that Golgi bodies become competent for cargo collection once they come to a halt on an ER ...
Chapter 26: Fluid, Electrolyte, and Acid-Base Balance
Chapter 26: Fluid, Electrolyte, and Acid-Base Balance

...  The role of sodium in controlling ECF volume and water distribution in the body is a result of:  Sodium being the only cation to exert significant osmotic pressure  Sodium ions leaking into cells and being pumped ...
Acetylation of Polysaccharides in Plant Cell Wall
Acetylation of Polysaccharides in Plant Cell Wall

... biomass based on plant cell wall is the production of biofuel. Using biofuels will exploit existing plant biomass and CO2 released during processing of biomass will be consumed by plants for photosynthesis and the overall effect of CO2 would be the same. Thus, this process will be carbon neutral. Mo ...
Miscellaneous
Miscellaneous

...  Oval Fat Bodies  They are often (but not always) seen in specimens with increased protein (proteinuria) & nephrotic syndrome. ...
Microscopic Sediment – Miscellaneous
Microscopic Sediment – Miscellaneous

... „ Oval Fat Bodies „ They are often (but not always) seen in specimens with increased protein (proteinuria) & nephrotic syndrome. ...
16_Chapter 4
16_Chapter 4

... proceeds along its burrow. Mucus also helps to bind soil particles together and preventing the burrow wall from collapsing. Mucus probably acts as a buffer system outside the body since it is secreted in large amounts when the animal is ...
High-Molecular-Weight Forms of Tyrosinase and the
High-Molecular-Weight Forms of Tyrosinase and the

... multiple steps (Table I). We have shown previo usly th at upon gelfiltration HPLC, dopachrome tautomerase activity m.i grated in th e void volume, corresponding to a Mr of at leas t 200 kD, alo ng with approximately 20% of th e total tyrosinase activity [18]. In contrast, 80% of tyrosinase activity ...
Pharmacol Rev.2006;58(2):194-243
Pharmacol Rev.2006;58(2):194-243

... Islet transplantation, on the other hand, promises to be a cure at least as effective as pancreas transplantation, while being much less invasive. Islet transplantation involves the isolation of functional islets from cadaveric, multiorgan donors. These islets are then injected into the hepatic port ...
A Comprehensive Mutational Analysis of the
A Comprehensive Mutational Analysis of the

... This implies that Thr-64, Asp-116, and/or Thr-161 in R82Ms-0 may contribute to the defense function of RPW8.2. By contrast, the R82Bg-1 allele contains the highest number (13) of nonsynonymous substitutions, including those resulting in T64S, D116G, and T161K amino acid replacements; however, plants ...
FREE Sample Here
FREE Sample Here

... DIF: DIF: DIF: DIF: DIF: DIF: DIF: DIF: DIF: DIF: DIF: ...
Post-transcriptional regulation of auxin transport proteins: cellular
Post-transcriptional regulation of auxin transport proteins: cellular

... exhibit both distinct and overlapping expression patterns throughout all stages of plant growth and development (Blakeslee et al., 2005b). The best characterized members of Arabidopsis ABCB proteins are the auxin transporters ABCB1, ABCB4, and ABCB19. Multiple reports have catalogued PIN and AUX/LAX ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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