Characterization and Evaluation of a Novel Tissue
... In current studies, we have confirmed that scaffolds glued with BTglue were noncytotoxic, with living cells spread across the entire surface of the BT-glue test area and cells growing directly on to the glued surfaces. With the long term aim of our studies being to create anatomically correct scaff ...
... In current studies, we have confirmed that scaffolds glued with BTglue were noncytotoxic, with living cells spread across the entire surface of the BT-glue test area and cells growing directly on to the glued surfaces. With the long term aim of our studies being to create anatomically correct scaff ...
Physical Interaction of Floral Organs Controls
... regulating petal identity and primordia growth are known, the molecular mechanism for the later elongation process remains unknown. We found a mutant, folded petals1 (fop1), in which normal petal development is inhibited during their growth through the narrow space between sepals and anthers, result ...
... regulating petal identity and primordia growth are known, the molecular mechanism for the later elongation process remains unknown. We found a mutant, folded petals1 (fop1), in which normal petal development is inhibited during their growth through the narrow space between sepals and anthers, result ...
Plant Growth Regulation
... 2,700 lM NAA for 1 h (k–l) or not (c–i). After removal of the embryo axis (EA) (a), mango cotyledons were cut crossly (b) or longitudinally (c) into 2 cm long segments, which were cultured on AM for the indicated days. (c–i) A first pattern of adventitious root formation at the PCS; (j–l) A second p ...
... 2,700 lM NAA for 1 h (k–l) or not (c–i). After removal of the embryo axis (EA) (a), mango cotyledons were cut crossly (b) or longitudinally (c) into 2 cm long segments, which were cultured on AM for the indicated days. (c–i) A first pattern of adventitious root formation at the PCS; (j–l) A second p ...
Calcium oscillations in higher plants Nicola H Evans*, Martin R
... Changes in the rate at which calcium enters and exits the cytosol are likely to form the basis of any mechanism that generates [Ca2+]cyt oscillations. These fluxes include influx and efflux across the plasma membrane and release and uptake into intracellular stores [2], including a contribution from ...
... Changes in the rate at which calcium enters and exits the cytosol are likely to form the basis of any mechanism that generates [Ca2+]cyt oscillations. These fluxes include influx and efflux across the plasma membrane and release and uptake into intracellular stores [2], including a contribution from ...
All you need to know about splenic arterial embolisation (or almost)
... catheter must be placed beyond the origin of the dorsal pancreatic artery. Then, embolic coils (the size of which is very important) are placed to occlude blood flow. The surgical equivalent of this procedure is splenic artery ligation. Proximal embolization performed exclusively with coils decrease ...
... catheter must be placed beyond the origin of the dorsal pancreatic artery. Then, embolic coils (the size of which is very important) are placed to occlude blood flow. The surgical equivalent of this procedure is splenic artery ligation. Proximal embolization performed exclusively with coils decrease ...
p23 and organization of the Golgi apparatus
... and is involved in sorting/trafficking in the early secretory pathway. In the present study, we have further investigated the role of p23 after ectopic expression. We found that ectopically expressed p23 folded and oligomerized properly, even after overexpression. However, in contrast to endogenous ...
... and is involved in sorting/trafficking in the early secretory pathway. In the present study, we have further investigated the role of p23 after ectopic expression. We found that ectopically expressed p23 folded and oligomerized properly, even after overexpression. However, in contrast to endogenous ...
ThioBridge™ conjugate
... An integrated solution for creation, selection and manufacture of next generation ADCs & other biopharmaceuticals ...
... An integrated solution for creation, selection and manufacture of next generation ADCs & other biopharmaceuticals ...
Specific Organization of Golgi Apparatus in Plant Cells
... and during cytokinesis. The preprophasic ring of microtubules and the phragmoplast are structures typical only for plant cells. The preprophasic ring is involved in determination of the future plate of the cell division and the phragmoplast participates in the targeted delivery of vesicles into the ...
... and during cytokinesis. The preprophasic ring of microtubules and the phragmoplast are structures typical only for plant cells. The preprophasic ring is involved in determination of the future plate of the cell division and the phragmoplast participates in the targeted delivery of vesicles into the ...
PureYield™ RNA Midiprep System Technical Manual
... greater than 20kb (2). High-quality total RNA is isolated with minimal effort for a wide range of applications. Note: This system has not been developed to isolate RNA from chemically preserved samples (e.g., formalin-fixed or paraffin-embedded tissues). The PureYield™ RNA Midiprep System provides m ...
... greater than 20kb (2). High-quality total RNA is isolated with minimal effort for a wide range of applications. Note: This system has not been developed to isolate RNA from chemically preserved samples (e.g., formalin-fixed or paraffin-embedded tissues). The PureYield™ RNA Midiprep System provides m ...
- Nottingham ePrints
... events that control myogenesis in developing limbs are distinct from those in somites. It has been suggested that limb myoblasts differentiate via a default pathway once they escape inhibitory BMP (Amthor et al., 1998). Nevertheless other signals are involved in limb myogenesis (Christ and Brand-Sab ...
... events that control myogenesis in developing limbs are distinct from those in somites. It has been suggested that limb myoblasts differentiate via a default pathway once they escape inhibitory BMP (Amthor et al., 1998). Nevertheless other signals are involved in limb myogenesis (Christ and Brand-Sab ...
LVA and HVA Ca Currents in Ventricular Muscle Cells of the
... been shown to enhance the amplitude of a number of types of voltage-gated Ca21 currents (Bean 1989a; Tsien et al. 1988), as well as being able to block certain K1 currents (Armstrong and Taylor 1980; Hille 1992; Latorre and Miller 1983). Its substitution for Ca21 in the extracellular solution would ...
... been shown to enhance the amplitude of a number of types of voltage-gated Ca21 currents (Bean 1989a; Tsien et al. 1988), as well as being able to block certain K1 currents (Armstrong and Taylor 1980; Hille 1992; Latorre and Miller 1983). Its substitution for Ca21 in the extracellular solution would ...
A GH3-like Domain in Reaper Is Required for Mitochondrial
... grown in T-25 flasks were transfected by mixing 10 g of Reaper, Reaper mutant, or SMAC with 1 g of EGFP/pCasper (a construct in which EGFP is driven by the constitutive ubiquitin promoter) and 48 l Cellfectin. To monitor transfection efficiency, 20% of the transfection mixture was plated with 50 ...
... grown in T-25 flasks were transfected by mixing 10 g of Reaper, Reaper mutant, or SMAC with 1 g of EGFP/pCasper (a construct in which EGFP is driven by the constitutive ubiquitin promoter) and 48 l Cellfectin. To monitor transfection efficiency, 20% of the transfection mixture was plated with 50 ...
Spatial localization of the first and last enzymes effectively connects
... our analysis to globular enzymes, excluding membranebound proteins, and by carefully chosing controls for the statistical analysis. Based on the localization classification shown in GenoBase we compiled the presence of 219 enzymes in the list of 516 non-membrane bound fusions that showed GFP focal d ...
... our analysis to globular enzymes, excluding membranebound proteins, and by carefully chosing controls for the statistical analysis. Based on the localization classification shown in GenoBase we compiled the presence of 219 enzymes in the list of 516 non-membrane bound fusions that showed GFP focal d ...
the article
... Systemic lupus erythematosus (SLE), the second most common human autoimmune disease, is characterized by autoantibodies to nuclear ‘autoantigens’, including DNA, RNA-associated proteins, core histones and chromatin1. Although the defects in normal immune homeostasis underlying this distinct autoanti ...
... Systemic lupus erythematosus (SLE), the second most common human autoimmune disease, is characterized by autoantibodies to nuclear ‘autoantigens’, including DNA, RNA-associated proteins, core histones and chromatin1. Although the defects in normal immune homeostasis underlying this distinct autoanti ...
Print - Circulation
... Experiments of this type reveal that the various subunits modulate sensitivity to dihydropyridine agonists, kinetics, and voltage dependence of activation and inactivation. The broad conclusion is that all subunits are required before the channel can fully express its native properties, although it ...
... Experiments of this type reveal that the various subunits modulate sensitivity to dihydropyridine agonists, kinetics, and voltage dependence of activation and inactivation. The broad conclusion is that all subunits are required before the channel can fully express its native properties, although it ...
Autophagy at the crossroads of catabolism and anabolism
... of the phagophore assembly site (PAS). This is mediated by the UNC51‑like kinase (ULK) complex, which consists of ULK1 (or ULK2), autophagy-related protein 13 (ATG13), FAK family kinase interacting protein of 200 kDa (FIP200) and ATG101. Further nucleation requires the class III PI3K complex, which ...
... of the phagophore assembly site (PAS). This is mediated by the UNC51‑like kinase (ULK) complex, which consists of ULK1 (or ULK2), autophagy-related protein 13 (ATG13), FAK family kinase interacting protein of 200 kDa (FIP200) and ATG101. Further nucleation requires the class III PI3K complex, which ...
Novel modification of the tetrapod cardiovascular system in
... Ramaswami (1944). Much of this variation concerns the extent of development of, and pathways taken by, the aortic arches. The aortic arches may be paired, with various degrees of bilateral size asymmetry, or either both or just one of the pulmonary and systemic arches may be single. In addition, the ...
... Ramaswami (1944). Much of this variation concerns the extent of development of, and pathways taken by, the aortic arches. The aortic arches may be paired, with various degrees of bilateral size asymmetry, or either both or just one of the pulmonary and systemic arches may be single. In addition, the ...
ETRS-WHS 2015 Abstracts Wound Repair Regen (PDF
... Cincinnati Children’s Hospital Medical Center, Cincinnati, OH USA; 2Stanford School of Medicine, Palo Alto, CA USA; 3Children’s Hospital Colorado, Aurora, CO USA; 4Texas Children’s Hospital, Houston, TX USA Introduction: Lentiviral-mediated interleukin (IL)-10 overexpression results in fetal-type re ...
... Cincinnati Children’s Hospital Medical Center, Cincinnati, OH USA; 2Stanford School of Medicine, Palo Alto, CA USA; 3Children’s Hospital Colorado, Aurora, CO USA; 4Texas Children’s Hospital, Houston, TX USA Introduction: Lentiviral-mediated interleukin (IL)-10 overexpression results in fetal-type re ...
The Aspergillus fumigatus cspA Gene Encoding a Repeat
... cspA (for cell surface protein A) encodes a repeat-rich glycophosphatidylinositol (GPI)-anchored cell wall protein (CWP) in the pathogenic fungus Aspergillus fumigatus. The number of repeats in cspA varies among isolates, and this trait is used for typing closely related strains of A. fumigatus. We ...
... cspA (for cell surface protein A) encodes a repeat-rich glycophosphatidylinositol (GPI)-anchored cell wall protein (CWP) in the pathogenic fungus Aspergillus fumigatus. The number of repeats in cspA varies among isolates, and this trait is used for typing closely related strains of A. fumigatus. We ...
Understanding PNH
... and destroy bacteria, viruses and abnormal cells. Normal blood cells have protective proteins on their surface, which are there to defend cells from attack by the complement system. These proteins are attached to the cell surface by a different group of proteins (GPI-anchor proteins) made by the PIG ...
... and destroy bacteria, viruses and abnormal cells. Normal blood cells have protective proteins on their surface, which are there to defend cells from attack by the complement system. These proteins are attached to the cell surface by a different group of proteins (GPI-anchor proteins) made by the PIG ...
PermaLink - Glythera
... Comparative cleavable/non-cleavable ADC models with supporting in-vitro/in-vivo assays Characterisation assays are based on typical CMC analytical methods ...
... Comparative cleavable/non-cleavable ADC models with supporting in-vitro/in-vivo assays Characterisation assays are based on typical CMC analytical methods ...
Drug Targets in Mycobacterial Sulfur Metabolism
... isoniazid, rifampin, pyrazinamide and ethambutol [4,5]. In large part, the lengthy drug therapy is necessary because mycobacteria exist as a metabolically diverse population within the human host [5]. Some bacteria will be actively dividing, rendering them susceptible to antibiotic treatment. Howeve ...
... isoniazid, rifampin, pyrazinamide and ethambutol [4,5]. In large part, the lengthy drug therapy is necessary because mycobacteria exist as a metabolically diverse population within the human host [5]. Some bacteria will be actively dividing, rendering them susceptible to antibiotic treatment. Howeve ...
Green glands
... attached to this body segment. abdomen The fan-like sections on either side of the telson in a crayfish’s tail uropods ...
... attached to this body segment. abdomen The fan-like sections on either side of the telson in a crayfish’s tail uropods ...
- WRAP: Warwick Research Archive Portal
... inhibition. For further drug development, other factors as cell uptake, organelle distribution and general metabolism then become important. Nevertheless, interesting parallels emerge between the design of ligands for complexes with catalytic and medicinal properties. 1 However, some differences pre ...
... inhibition. For further drug development, other factors as cell uptake, organelle distribution and general metabolism then become important. Nevertheless, interesting parallels emerge between the design of ligands for complexes with catalytic and medicinal properties. 1 However, some differences pre ...