• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Mitochondrial fusion dynamics is robust in the heart and depends on
Mitochondrial fusion dynamics is robust in the heart and depends on

... cells that we have studied previously, including mouse embryonic fibroblasts (MEFs), H9c2 cells, hepatocytes, and skeletal muscle fiber cells (7, 17, 35), AVCMs exhibited diverse mixing kinetics of the matrix-targeted fluorescent proteins (Fig. 3). Two representative examples are shown in Fig. 3A an ...
Phloem transport: A review of mechanisms and controls (PDF
Phloem transport: A review of mechanisms and controls (PDF

... mechanisms can be active or passive, and apoplastic (the sugars enter the apoplast at least once by crossing the cell membrane) or symplastic (entirely through the plasmodesmata-connected cytosol of cells) (Turgeon, 2010b). The apoplast refers to the continuous system of cell walls and xylem vessels ...
Phloem transport: a review of mechanisms and
Phloem transport: a review of mechanisms and

... mechanisms can be active or passive, and apoplastic (the sugars enter the apoplast at least once by crossing the cell membrane) or symplastic (entirely through the plasmodesmata-connected cytosol of cells) (Turgeon, 2010b). The apoplast refers to the continuous system of cell walls and xylem vessels ...
The mating pair stabilization protein, TraN, of the F plasmid is an
The mating pair stabilization protein, TraN, of the F plasmid is an

... F plasmid TraN (602 aa, processed to 584 aa with 22 conserved cysteines), which is essential for F plasmid conjugation, is an outer-membrane protein involved in mating pair stabilization (MPS). Unlike R100 TraN, F TraN requires OmpA in the recipient cell for efficient MPS. The authors have identifie ...
Transcriptional regulation of mammalian autophagy at a glance
Transcriptional regulation of mammalian autophagy at a glance

... released from lysosomes to enable some maintenance of the cellular energy status (Rabinowitz and White, 2010). Indeed, starvation leads to inhibition of mammalian target of rapamycin complex 1 (mTORC1), a negative regulator of autophagy, and activation of Jun N-terminal kinase (JNK; also known as MA ...
Fig. 2a
Fig. 2a

... Polymorphisms in the gene encoding the transcription factor IRF5 that lead to higher mRNA expression are associated with many autoimmune diseases. Here we show that IRF5 expression in macrophages was reversibly induced by inflammatory stimuli and contributed to the plasticity of macrophage polarizat ...
The mitochondrial compartment - Plant Mitochondrial dynamics
The mitochondrial compartment - Plant Mitochondrial dynamics

... cell death (Jones, 2000; Youle and Karbowski, 2005). This review deals with the complex biology of the mitochondrion and describes how various levels of compartmentalization within the mitochondrion and cellular mitochondrial population as a whole (the chondriome) underpin the multiple functions of ...
Functional Regulation of MyD88-Activated Interferon Regulatory
Functional Regulation of MyD88-Activated Interferon Regulatory

... role of these interactions in the regulation of IRF-5, we examined the role of ubiquitination and showed that IRF-5 is subjected to TRAF6-mediated K63-linked ubiquitination, which is important for IRF-5 nuclear translocation and target gene regulation. We show that while the murine IRF-5 and human I ...
SYLLABUS 0610
SYLLABUS 0610

... The syllabus content has been revised and updated to modernise and improve the relevance of the syllabus. The wording of some learning outcomes has been changed for clarification. Some material has been reordered, removed, moved between sections, or reclassified as either Core or Supplement material ...
The Role of Cyclin B in Meiosis I
The Role of Cyclin B in Meiosis I

... play any role in controlling the very early cell cycles. Instead, during the cleavage divisions, the cells seem to rely entirely on internal regulation. The key regulatory events control the rise in MPF activity across the cycle, which drives cells into M phase, and the loss of MPF activity at the e ...
IGCSE Biology - Cambridge International Examinations
IGCSE Biology - Cambridge International Examinations

... The syllabus content has been revised and updated to modernise and improve the relevance of the syllabus. The wording of some learning outcomes has been changed for clarification. Some material has been reordered, removed, moved between sections, or reclassified as either Core or Supplement material ...
Biofilms
Biofilms

... skin formation by hydrophobic EPS molecules enhances the ability of the biofilm to survive desiccation. Biofilms derive several emergent properties — that is, properties that are not predictable from the study of free-living bacterial cells — from the EPS matrix. These properties include localized g ...
Decontamination of the BD FACSAria II: Is the
Decontamination of the BD FACSAria II: Is the

... • Used (on purpose) in experiments to induce these cytokine responses for research studies ...
Arthropod flip - local.brookings.k12.sd.us
Arthropod flip - local.brookings.k12.sd.us

... attached to this body segment. abdomen The fan-like sections on either side of the telson in a crayfish’s tail uropods ...
NORDINImmunomodulatoryEffects2012 - QMRO Home
NORDINImmunomodulatoryEffects2012 - QMRO Home

... Studies on the effects of HB02, its fractions and compounds showed inhibitory effects on the level of mRNA for iNOS, TNFα, IL-12p40 and IL-23p19 in pretreatment experiments of macrophages. Studies of cell migration showed that the ...
Isoprenoid biosynthesis in bacterial pathogens
Isoprenoid biosynthesis in bacterial pathogens

... (HMGR) is present in all four sequenced Vibrio species (V. cholerae, Vibrio vulnificus, Vibrio parahaemolyticus and Vibrio fischeri). Gophna et al. (2006) examined the evolutionary history of hmgR within these species, and their data suggest that hmgR was acquired by an ancestral Vibrio in a single ...
Adhesion and Adhesives of Fungi and Oomycetes
Adhesion and Adhesives of Fungi and Oomycetes

... adhesion may facilitate “preparation of the infection court,” i.e., alteration of the host surface so that it favors fungal development (see Sect. 2.2.3.1). That is, a tightly adherent spore or germling may be able to effectively maintain a higher concentration of its lytic enzymes at the interface ...
Operator`s manual - ReMed Medical Equipment
Operator`s manual - ReMed Medical Equipment

... intended for use in today’s growing professional healthcare environment, including healthcare facilities and home care, for use on adults, pediatrics and neonates. Instrument is intended for facilities that utilize infusion pumps for the delivery of fluids, medications, blood and blood products usin ...
Chromosome Segregation in Budding Yeast: Sister Chromatid
Chromosome Segregation in Budding Yeast: Sister Chromatid

... Early on, it was recognized that the two sister chromatids must be held tightly together at metaphase to resist spindle forces, thereby allowing their attachment to microtubules from opposite poles. However, the nature of this cohesion was not known and two general models were put forward. One model ...
Innate antiviral defense of zebrafish : from signalling to specialized
Innate antiviral defense of zebrafish : from signalling to specialized

... replicate and hence evolve very quickly. To cope with such pathogens, metazoans developed a number of different strategies, from downregulation of cellular machinery or induced cell death to synthesis of specific antibodies. In vertebrates, both innate and adaptive immune strategies are used in anti ...
Research and Development
Research and Development

... surface, and is caused by a chemical reaction initiated when tuber cells are physically damaged. This phenomenon greatly affects the quality of the crop and its value. A 2-year, BPC/DEFRA funded programme at the University of Durham under the direction of Dr Ron Croy has made significant advances in ...
The Photopic ERG Luminance-response Function
The Photopic ERG Luminance-response Function

... The retina is a thin transparent layer that lies against the back of the eye ball. Rays of light refracted by the cornea and the lens and entering the eye through the pupil must pass through the entire retinal thickness before reaching the photoreceptors, the main lightsensitive cells of the retina. ...
galathea-vol.03-pp_009-072
galathea-vol.03-pp_009-072

... the moment of fixation. The whole dorsum is covered by a single, almost circular, cap-shaped shell, hiding the soft parts when the animal is viewed from all sides except the ventral one (Figs. 1-7). The ventral side of the animal is soft, the epithelial surface almost everywhere being naked and ofte ...
Activation of ryanodine receptors induces calcium influx in a
Activation of ryanodine receptors induces calcium influx in a

... we have examined the hypothesis that the 401L cell requires activation of RyRs to induce Ca2+ influx, a role described for RyRs in other neuronal cell types [9,10]. In the present study we report, using RT (reverse transcriptase)–PCR, the expression of mRNAs encoding two RyR isoforms (RyR1 and RyR2) ...
Review Role of a novel photopigment, melanopsin, in behavioral
Review Role of a novel photopigment, melanopsin, in behavioral

... are already evident at birth (P0) [23, 24], long before detectable rod/cone photosensitivity first appears on postnatal day P10 [25]. Any functional significance of such early photosensitivity in melanopsin-containing cells is currently unknown, but could reflect an adaptive advantage to circadian p ...
< 1 ... 19 20 21 22 23 24 25 26 27 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report