Synaptic plasticity: taming the beast
... induces LTP or LTD (Fig. 2a–c ). In other cases, synaptic plasticity depends on the relative timing of the pre- and postsynaptic spikes, but not on their order ( Fig. 2d and e). In the cerebellum-like structure of electric fish, LTP and LTD are reversed relative to other systems (Fig. 2c ), perhaps ...
... induces LTP or LTD (Fig. 2a–c ). In other cases, synaptic plasticity depends on the relative timing of the pre- and postsynaptic spikes, but not on their order ( Fig. 2d and e). In the cerebellum-like structure of electric fish, LTP and LTD are reversed relative to other systems (Fig. 2c ), perhaps ...
Emotional Arousal and Memory Binding
... memory binding and explain these contradictory findings using an object-based framework. According to this framework, emotionally arousing objects attract attention that enhances binding of their constituent features. In contrast, the emotional arousal associated with one object either impairs or ha ...
... memory binding and explain these contradictory findings using an object-based framework. According to this framework, emotionally arousing objects attract attention that enhances binding of their constituent features. In contrast, the emotional arousal associated with one object either impairs or ha ...
Exercise and Anxiety Take Home Messages
... Treadmill exercise and wheel exercise enhance expressions of neutrophic factors in the hippocampus of lipopolysaccharide-injected rats S-E Kim, I-G Ko, M-S Shin, C-J Kim, B-K Jin, H-P Hong, Y-S Jee 2013 Neuroscience Letters 538: 54–59 1. Exercise improves depressive symptoms and anxiety a. Enhances ...
... Treadmill exercise and wheel exercise enhance expressions of neutrophic factors in the hippocampus of lipopolysaccharide-injected rats S-E Kim, I-G Ko, M-S Shin, C-J Kim, B-K Jin, H-P Hong, Y-S Jee 2013 Neuroscience Letters 538: 54–59 1. Exercise improves depressive symptoms and anxiety a. Enhances ...
Powerpoint Slides - people.csail.mit.edu
... • Tdap viruses are grown on a protein source derived from bovine casein (protein in milk) • Casein has significant amounts of glycine which could be displaced by glyphosate • Tdap also contains aluminum, which is a neurotoxin • Aluminum and glyphosate are synergistically toxic ...
... • Tdap viruses are grown on a protein source derived from bovine casein (protein in milk) • Casein has significant amounts of glycine which could be displaced by glyphosate • Tdap also contains aluminum, which is a neurotoxin • Aluminum and glyphosate are synergistically toxic ...
Towards the construction of Escherichia coli cell
... Cell-free protein systems are described as the in vitro expression of recombinant proteins without the use of living cells. This approach uses a cell lysate containing a wide array of biological and chemical components for transcription, translation, protein folding, and energy metabolism; all requi ...
... Cell-free protein systems are described as the in vitro expression of recombinant proteins without the use of living cells. This approach uses a cell lysate containing a wide array of biological and chemical components for transcription, translation, protein folding, and energy metabolism; all requi ...
Verbal memory in mesial temporal lobe epilepsy
... memory, particularly if seizure outcome is poor (Helmstaedter et al., 2003). The most influential conceptualization of memory impairment in temporal lobe epileptology is, unquestionably, the notion of material-specificity. This parsimonious model owes much to the pioneering work of Brenda Milner and h ...
... memory, particularly if seizure outcome is poor (Helmstaedter et al., 2003). The most influential conceptualization of memory impairment in temporal lobe epileptology is, unquestionably, the notion of material-specificity. This parsimonious model owes much to the pioneering work of Brenda Milner and h ...
Retrograde Signaling in the Development and Modification of
... and connectin, were found to prevent formation of selective innervation by the proper motoneuron when they were expressed at high levels on the target muscle fibers (244, 272), suggesting a repulsive action of these molecules on the growth cone of specific motoneurons. These results from the Drosoph ...
... and connectin, were found to prevent formation of selective innervation by the proper motoneuron when they were expressed at high levels on the target muscle fibers (244, 272), suggesting a repulsive action of these molecules on the growth cone of specific motoneurons. These results from the Drosoph ...
Overgeneralized autobiographical memory and future
... reasons. First, this is the first effort to examine the phenomenon of future thinking in combat veterans with and without PTSD. To that end, as stated, the paradigm was closely modeled after the now well-replicated paradigm employed in behavioral and brain imagining studies by Addis, Schacter, and co ...
... reasons. First, this is the first effort to examine the phenomenon of future thinking in combat veterans with and without PTSD. To that end, as stated, the paradigm was closely modeled after the now well-replicated paradigm employed in behavioral and brain imagining studies by Addis, Schacter, and co ...
Identification of a Functional Connectome for Long
... network organization at a global level. Accordingly, we categorized our 84 regions into major brain subdivisions (e.g., neocortex, hippocampus, midbrain, cerebral nuclei; Table S1) and asked whether connection strength between these major subdivisions differed at the 1 day and 36 day time-points (se ...
... network organization at a global level. Accordingly, we categorized our 84 regions into major brain subdivisions (e.g., neocortex, hippocampus, midbrain, cerebral nuclei; Table S1) and asked whether connection strength between these major subdivisions differed at the 1 day and 36 day time-points (se ...
The cognitive neuroscience of constructive memory
... are likely to be falsely recognized, while unrelated words that do not match it are likely to be correctly rejected. As a result of MTL damage, amnesic and AD patients may form and retain only a weak or degraded gist representation and thus make fewer false alarms to ...
... are likely to be falsely recognized, while unrelated words that do not match it are likely to be correctly rejected. As a result of MTL damage, amnesic and AD patients may form and retain only a weak or degraded gist representation and thus make fewer false alarms to ...
Impact of diet on adult hippocampal neurogenesis
... correlation; therefore, it is possible that other factors such as structural plasticity, neurotrophin or hormone levels also contribute to genetically and environmentally induced changes in hippocampus-dependent learning and memory. Newborn neurons represent only a small cell population within the a ...
... correlation; therefore, it is possible that other factors such as structural plasticity, neurotrophin or hormone levels also contribute to genetically and environmentally induced changes in hippocampus-dependent learning and memory. Newborn neurons represent only a small cell population within the a ...
Amyloid inhibits retinoic acid synthesis exacerbating Alzheimer
... Donmez et al., 2010; Jarvis et al., 2010). It has not yet been shown how a deficit in RA signalling could occur. Given the recently documented inverse correlation between intracellular calcium concentration and RA synthesis (Wang et al., 2011) and the role of Ab in increasing intracellular calcium (C ...
... Donmez et al., 2010; Jarvis et al., 2010). It has not yet been shown how a deficit in RA signalling could occur. Given the recently documented inverse correlation between intracellular calcium concentration and RA synthesis (Wang et al., 2011) and the role of Ab in increasing intracellular calcium (C ...
Long-Term Depression in Identified Stellate Neurons of Juvenile Rat
... innervates the dentate gyrus granule cells. We initially examined the long-term plasticity at the stellate neuron synapses. We recorded from the stellate neurons in layer II of the EC and stimulated the inputs from the deep layers by placing a stimulation electrode in layer IV (Fig. 1A). After recor ...
... innervates the dentate gyrus granule cells. We initially examined the long-term plasticity at the stellate neuron synapses. We recorded from the stellate neurons in layer II of the EC and stimulated the inputs from the deep layers by placing a stimulation electrode in layer IV (Fig. 1A). After recor ...
Document
... Interest in using blue lupin as an alternative protein source in animal feed and also part of a healthy diet. In Finland, only 1 farm cultivating blue lupin for human consumption ...
... Interest in using blue lupin as an alternative protein source in animal feed and also part of a healthy diet. In Finland, only 1 farm cultivating blue lupin for human consumption ...
PDF - Oxford Academic - Oxford University Press
... endowed with a Mexican-hat architecture (Amari 1977; BenYishai et al. 1995), with local excitation between pyramidal cells with similar spatial preference and broad synaptic inhibition from c-aminobutyric acidergic (GABAergic) cells. When the strength of recurrent excitatory synapses is sufficiently ...
... endowed with a Mexican-hat architecture (Amari 1977; BenYishai et al. 1995), with local excitation between pyramidal cells with similar spatial preference and broad synaptic inhibition from c-aminobutyric acidergic (GABAergic) cells. When the strength of recurrent excitatory synapses is sufficiently ...
PDF of original
... one molecule of hexa-A m a y be recognized by two Lys-sRNA molecules bound to adjacent ribosomal sites (Rottman and Nirenberg, 1966). An extensively purified doublet with 5'-terminal phosphate, pUpC, serves as a template for SersRNA (but not for Leu- or Ile-sRNA), whereas a doublet without terminal ...
... one molecule of hexa-A m a y be recognized by two Lys-sRNA molecules bound to adjacent ribosomal sites (Rottman and Nirenberg, 1966). An extensively purified doublet with 5'-terminal phosphate, pUpC, serves as a template for SersRNA (but not for Leu- or Ile-sRNA), whereas a doublet without terminal ...
ARTICLE IN PRESS Neural Networks entorhinal cortex
... A potential difficulty for implementing a phase code with membrane potential oscillations concerns the tendency for oscillations within different parts of a single neuron to synchronize, as shown in computational studies (Remme, Lengyel, & Gutkin, 2007). Previous models have proposed that the relati ...
... A potential difficulty for implementing a phase code with membrane potential oscillations concerns the tendency for oscillations within different parts of a single neuron to synchronize, as shown in computational studies (Remme, Lengyel, & Gutkin, 2007). Previous models have proposed that the relati ...
Amygdala oscillations and the consolidation of
... responses, identification of the emotional content of sensory stimuli, and aspects of social cognition [6]. Moreover, much data suggest that the amygdala enhances memory consolidation in emotionally arousing conditions [4]. Briefly, neuromodulators released in emotionally arousing conditions appear ...
... responses, identification of the emotional content of sensory stimuli, and aspects of social cognition [6]. Moreover, much data suggest that the amygdala enhances memory consolidation in emotionally arousing conditions [4]. Briefly, neuromodulators released in emotionally arousing conditions appear ...
Original Article Female Rat Hippocampal Cell
... belong to a large family of G protein-coupled receptors and play an important physiological role (Piestrzeniewicz et al., 2006). Recent reports support the view that the hippocampus is also involved in addiction to opiates and other drugs. Some studies suggest that the hippocampus is important for r ...
... belong to a large family of G protein-coupled receptors and play an important physiological role (Piestrzeniewicz et al., 2006). Recent reports support the view that the hippocampus is also involved in addiction to opiates and other drugs. Some studies suggest that the hippocampus is important for r ...
Mushroom body efferent neurons responsible for aversive olfactory
... Neurons in the MB-V2 cluster are the only GAL4-expressing cells that are clearly shared by NP2492 and MZ160, but each line shows expression in additional brain regions, such as the fan-shaped body in NP2492 (Supplementary Fig. 1a and Supplementary Video 1) and the optic lobes in MZ160 (Supplementary ...
... Neurons in the MB-V2 cluster are the only GAL4-expressing cells that are clearly shared by NP2492 and MZ160, but each line shows expression in additional brain regions, such as the fan-shaped body in NP2492 (Supplementary Fig. 1a and Supplementary Video 1) and the optic lobes in MZ160 (Supplementary ...
Habituation, sensitization and Pavlovian conditioning
... Identification of the necessary and sufficient conditions for the formation of associations has been a driving influence on learning theory and research. In Pavlovian conditioning, a conditioned stimulus (CS) acquires the ability to trigger a new response by virtue of being paired with an unconditio ...
... Identification of the necessary and sufficient conditions for the formation of associations has been a driving influence on learning theory and research. In Pavlovian conditioning, a conditioned stimulus (CS) acquires the ability to trigger a new response by virtue of being paired with an unconditio ...
Cortical EEG correlates of successful memory encoding
... relational condition, participants were required to internally reorder the items as a function of desirability. Encoding-related activity in the hippocampus was greater in the relational as compared to the item-based condition, whereas the reversed comparison revealed superior activation in entorhin ...
... relational condition, participants were required to internally reorder the items as a function of desirability. Encoding-related activity in the hippocampus was greater in the relational as compared to the item-based condition, whereas the reversed comparison revealed superior activation in entorhin ...
Stress effects on memory
... memory retrieval, the memory trace can re-enter an unstable state so that a reconsolidation process is needed to stabilize it anew (Dudai, 2006). Stress may have an effect on all these processes – encoding, consolidation, retrieval, and reconsolidation (or extinction). How stress influences memory de ...
... memory retrieval, the memory trace can re-enter an unstable state so that a reconsolidation process is needed to stabilize it anew (Dudai, 2006). Stress may have an effect on all these processes – encoding, consolidation, retrieval, and reconsolidation (or extinction). How stress influences memory de ...
Neural changes underlying the development of
... The hippocampus develops rapidly in the first years of life and more subtly thereafter. For example, hippocampal volumes have been found to double from birth to the first year, with further increases in the second year (Gilmore et al., 2011). After the first few years of life, volumetric changes are li ...
... The hippocampus develops rapidly in the first years of life and more subtly thereafter. For example, hippocampal volumes have been found to double from birth to the first year, with further increases in the second year (Gilmore et al., 2011). After the first few years of life, volumetric changes are li ...
Protein Synthesis in Cell-Free Reticulocyte Lysates on Multi
... concentrationsof a varietv tli compoLlnclsto maintain transiation(9,13,14). A major require'ment olt the. rr.ticulocrrteh'satr. is for henrc in rlrdr-r trr m a i n t a i n t r a n s l a t i o n a la c t i v i t v f o r m o r e t h a n - 1 0 m i n ( 1 1 , 1 5 - 1 9 ) l.i e m e ' i n h i b i t s t h e ...
... concentrationsof a varietv tli compoLlnclsto maintain transiation(9,13,14). A major require'ment olt the. rr.ticulocrrteh'satr. is for henrc in rlrdr-r trr m a i n t a i n t r a n s l a t i o n a la c t i v i t v f o r m o r e t h a n - 1 0 m i n ( 1 1 , 1 5 - 1 9 ) l.i e m e ' i n h i b i t s t h e ...