The case of KC: contributions of a memory
... The case of K.C. turned out to be one contributor to the eventual crumbling of the neat and tidy single-memory, single-locus model of amnesia. Today, there are as many puzzles surrounding memory impairment as there are surrounding “normal” memory. For instance, it is becoming increasingly clear that ...
... The case of K.C. turned out to be one contributor to the eventual crumbling of the neat and tidy single-memory, single-locus model of amnesia. Today, there are as many puzzles surrounding memory impairment as there are surrounding “normal” memory. For instance, it is becoming increasingly clear that ...
The Synthesis of Enzymes Concerned in Bacterio
... synthesis have been studied in cultures of Rhodopseudornonas spheroides growing exponentially. In organisms growing in the dark under high degrees of aeration the differential rate of synthesis (increase in enzyme/increase in culture density) of both enzymes is about one-third of that in cultures gr ...
... synthesis have been studied in cultures of Rhodopseudornonas spheroides growing exponentially. In organisms growing in the dark under high degrees of aeration the differential rate of synthesis (increase in enzyme/increase in culture density) of both enzymes is about one-third of that in cultures gr ...
De Novo Pyrimidine Nucleotide Synthesis Mainly
... observed (see Supplemental Figure 1 online). Cleavage is assumed to occur in the periplasmic space of the bacterial cells by corresponding enzyme activities as shown for adenosine (Watanabe et al., 2011). Therefore, the question whether nucleosides are also substrates of PLUTO cannot be addressed wi ...
... observed (see Supplemental Figure 1 online). Cleavage is assumed to occur in the periplasmic space of the bacterial cells by corresponding enzyme activities as shown for adenosine (Watanabe et al., 2011). Therefore, the question whether nucleosides are also substrates of PLUTO cannot be addressed wi ...
De Novo Pyrimidine Nucleotide Synthesis Mainly
... et al., 2009; www.tcdb.org). The closest Arabidopsis homolog to this protein is encoded by At5g03555. The deduced amino acid sequence exhibits 23% identity and 43% similarity to FUR4 (Figure 2). The N terminus of the At5g03555 translation product contains a predicted target sequence for chloroplasts ...
... et al., 2009; www.tcdb.org). The closest Arabidopsis homolog to this protein is encoded by At5g03555. The deduced amino acid sequence exhibits 23% identity and 43% similarity to FUR4 (Figure 2). The N terminus of the At5g03555 translation product contains a predicted target sequence for chloroplasts ...
Neuronal Activity in the Hippocampus During Delayed Non
... found that performance on an odor-guided delayed nonmatching task was impaired by perirhinal-entorhinal cortex lesions but not by fornix transection (Otto and Eichenbaum, 1992). This pattern of results led us to suggest that parahippocampal areas may be sufficient to support recognition memory acros ...
... found that performance on an odor-guided delayed nonmatching task was impaired by perirhinal-entorhinal cortex lesions but not by fornix transection (Otto and Eichenbaum, 1992). This pattern of results led us to suggest that parahippocampal areas may be sufficient to support recognition memory acros ...
Distinct or Gradually Changing Spatial and Nonspatial
... out a continuous theta oscillation. Moreover, the nature of theta oscillation in the bat’s dorsal hippocampus was intermittent (Ulanovsky and Moss, 2007), much like the intermittent theta reported by Royer et al. (2010) in the rat ventral hippocampus. The existence of place cells without continuous ...
... out a continuous theta oscillation. Moreover, the nature of theta oscillation in the bat’s dorsal hippocampus was intermittent (Ulanovsky and Moss, 2007), much like the intermittent theta reported by Royer et al. (2010) in the rat ventral hippocampus. The existence of place cells without continuous ...
EUGENE GARFIELD
... behavioral sensitimtion in Aplysia califomica. Proc. Naf. Aced. Sci. CJSA75:3512-6, 1978. Kandel E R & Tmm L. Anomalous rcctifkation in the metacerehrsl giant cells snd its consequences for symptic transmission. J. P/rysiof. -London 183:287-304, 1966. Cmdefhtrci V, Pfmker H, Kupfemuum I & Kandel E R ...
... behavioral sensitimtion in Aplysia califomica. Proc. Naf. Aced. Sci. CJSA75:3512-6, 1978. Kandel E R & Tmm L. Anomalous rcctifkation in the metacerehrsl giant cells snd its consequences for symptic transmission. J. P/rysiof. -London 183:287-304, 1966. Cmdefhtrci V, Pfmker H, Kupfemuum I & Kandel E R ...
Proceedings from the 2015 UK-Korea Neuroscience Symposium
... Spontaneous neurotransmitter release is a core element of synaptic communication in mature neurons, but little is known of its function during neuronal development. Using genetically encoded reporters of presynaptic release, we found that developing axons exhibit exceptionally high levels of spontan ...
... Spontaneous neurotransmitter release is a core element of synaptic communication in mature neurons, but little is known of its function during neuronal development. Using genetically encoded reporters of presynaptic release, we found that developing axons exhibit exceptionally high levels of spontan ...
Distinct Isoforms of the RFX Transcription Factor DAF
... To study the subcellular localization and developmental dynamics of DAF-19, we generated antibodies against Nand C-terminal epitopes AbDAF19N and AbDAF19C, respectively. In wild-type worms, these two antibodies detected different DAF-19 expression patterns (see below), which suggested the existence ...
... To study the subcellular localization and developmental dynamics of DAF-19, we generated antibodies against Nand C-terminal epitopes AbDAF19N and AbDAF19C, respectively. In wild-type worms, these two antibodies detected different DAF-19 expression patterns (see below), which suggested the existence ...
Neural Global Pattern Similarity Underlies True and False Memories
... associated reaction times in the recognition test. To measure the effect of semantic similarity on recognition memory, Pearson correlation was calculated between the memory scores in the recognition test and semantic global similarity ratings (i.e., sGS), which were obtained by averaging the semanti ...
... associated reaction times in the recognition test. To measure the effect of semantic similarity on recognition memory, Pearson correlation was calculated between the memory scores in the recognition test and semantic global similarity ratings (i.e., sGS), which were obtained by averaging the semanti ...
How the hippocampus preserves order: the role of
... an attenuated response in the same way that an attenuated response is observed on the second presentation of perceptually repeating items [37]. In this way, predicting and then seeing an item may look similar to seeing an item twice and hence result in repetition attenuation. An enhanced repetition ...
... an attenuated response in the same way that an attenuated response is observed on the second presentation of perceptually repeating items [37]. In this way, predicting and then seeing an item may look similar to seeing an item twice and hence result in repetition attenuation. An enhanced repetition ...
Molecular Analysis of Developmental Plasticity in Neocortex
... involved in long-term synaptic plasticity, during learning and memory as well as LTP (Frank and Greenberg, 1994; Martin and Kandel, 1996; Stevens, 1994). Recently transgenic and gene-transfer technologies in mice have allowed genetic manipulation of genes suspected to be involved in plasticity. Knoc ...
... involved in long-term synaptic plasticity, during learning and memory as well as LTP (Frank and Greenberg, 1994; Martin and Kandel, 1996; Stevens, 1994). Recently transgenic and gene-transfer technologies in mice have allowed genetic manipulation of genes suspected to be involved in plasticity. Knoc ...
Print this article - University of Toronto Journal of Undergraduate Life
... The treatment of Parkinson’s disease (PD) relies heavily on levodopa therapy. Although highly effective in ameliorating the debilitating symptoms of PD, levodopa treatment is largely associated with the development of abnormal involuntary movements. Several studies have suggested that these motor co ...
... The treatment of Parkinson’s disease (PD) relies heavily on levodopa therapy. Although highly effective in ameliorating the debilitating symptoms of PD, levodopa treatment is largely associated with the development of abnormal involuntary movements. Several studies have suggested that these motor co ...
The retrieval of perceptual memory details depends on right
... Gonzales, & Booth, 2007), which was derived from transcripts of post-scan memory descriptions. Previously, we have shown that this word count measure correlates with manual counts of memory details that reflect perceptual content (StLaurent et al., 2014). We predicted positive correlations between w ...
... Gonzales, & Booth, 2007), which was derived from transcripts of post-scan memory descriptions. Previously, we have shown that this word count measure correlates with manual counts of memory details that reflect perceptual content (StLaurent et al., 2014). We predicted positive correlations between w ...
STUFF TO ADD:
... sensory and association cortex: visual stimuli activate visual cortex, auditory stimuli activate auditory cortex, and so on. The MTL then encodes the experience by binding together these disparate brain regions, thus forming conscious associations among stimuli that are presented at the same time (S ...
... sensory and association cortex: visual stimuli activate visual cortex, auditory stimuli activate auditory cortex, and so on. The MTL then encodes the experience by binding together these disparate brain regions, thus forming conscious associations among stimuli that are presented at the same time (S ...
ARTICLE IN PRESS
... in the recall of internal details from an episodic memory after lesions of the hippocampus and parahippocampal cortices [96,162]. As shown in Fig. 1, the corresponding structures exist in the rat, allowing detailed experiments on physiological dynamics of neurons in these regions that could mediate ...
... in the recall of internal details from an episodic memory after lesions of the hippocampus and parahippocampal cortices [96,162]. As shown in Fig. 1, the corresponding structures exist in the rat, allowing detailed experiments on physiological dynamics of neurons in these regions that could mediate ...
The seasonal hippocampus of food-storing birds.
... points – October, January, April and July – and because the birds had previously been banded we were able to ensure our samples included only adults one year of age or older (Hoshooley et al., 2007). Birds were given BrdU on the day following capture then held in captivity for 7 days to permit obser ...
... points – October, January, April and July – and because the birds had previously been banded we were able to ensure our samples included only adults one year of age or older (Hoshooley et al., 2007). Birds were given BrdU on the day following capture then held in captivity for 7 days to permit obser ...
Partial Purification and Characterization of Three Flavonol
... Three distinct flavonol-specific sulfotransferases were partially purified from the shoot tips of Flaveria chloraefolia A. Gray by fractional precipitation with ammonium sulfate, followed by gel filtration on Sephacryl S-200, 3'-phosphoadenosine 5-phosphateAgarose affinity chromatography and chromat ...
... Three distinct flavonol-specific sulfotransferases were partially purified from the shoot tips of Flaveria chloraefolia A. Gray by fractional precipitation with ammonium sulfate, followed by gel filtration on Sephacryl S-200, 3'-phosphoadenosine 5-phosphateAgarose affinity chromatography and chromat ...
Enhanced intrinsic excitability and EPSP
... Running head: Environmental enrichment and hippocampal plasticity Keywords: Contextual fear learning; action potential threshold; theta-burst stimulation; miniature excitatory postsynaptic currents, after-hyperpolarization ...
... Running head: Environmental enrichment and hippocampal plasticity Keywords: Contextual fear learning; action potential threshold; theta-burst stimulation; miniature excitatory postsynaptic currents, after-hyperpolarization ...
Journal of Biological Chemistry
... prevents the ethionine-induced inhibition of incorporation, whereas adenosine does so only partially. The results with adenosine have been somewhat variable, in that sometimes it is found to be completely effective whereas at other times only partially so. This may be due to the very low solubility ...
... prevents the ethionine-induced inhibition of incorporation, whereas adenosine does so only partially. The results with adenosine have been somewhat variable, in that sometimes it is found to be completely effective whereas at other times only partially so. This may be due to the very low solubility ...
PKA, PKC, and AKAP localization in and around the neuromuscular
... Results: Immunohistochemistry and confocal microscopy were used here to determine that DAKAP1 colocalizes with RIα at the postsynaptic membrane of the vertebrate neuromuscular junction (NMJ) and the adjacent muscle, but not in the presynaptic region. The labeling pattern for RIα and D-AKAP1 overlapp ...
... Results: Immunohistochemistry and confocal microscopy were used here to determine that DAKAP1 colocalizes with RIα at the postsynaptic membrane of the vertebrate neuromuscular junction (NMJ) and the adjacent muscle, but not in the presynaptic region. The labeling pattern for RIα and D-AKAP1 overlapp ...
Role of the hippocampus in remembering the past and imagining
... finding raised the possibility that age-related loss of hippocampal function might underlie the impaired ability to remember the 19046 | www.pnas.org/cgi/doi/10.1073/pnas.1014391107 ...
... finding raised the possibility that age-related loss of hippocampal function might underlie the impaired ability to remember the 19046 | www.pnas.org/cgi/doi/10.1073/pnas.1014391107 ...
The Temporal Profile of 72-kDa Heat
... be the complete explanation for selective vulnerability (Auer et al., 1988). For example, there is little change in extracellular glutamate during prolonged epileptic seizures (Lehmann et al., 1985), and during hypoglycemia, aspartate increases while glutamate decreases (Agardh et al., 1978). Additi ...
... be the complete explanation for selective vulnerability (Auer et al., 1988). For example, there is little change in extracellular glutamate during prolonged epileptic seizures (Lehmann et al., 1985), and during hypoglycemia, aspartate increases while glutamate decreases (Agardh et al., 1978). Additi ...
NMDA and AMPA Receptors: Development and Status Epilepticus
... isoxazol-4-yl) propanoic acid (AMPA) and kainate (KA). During early stages of postnatal development glutamate receptors of NMDA and AMPA type undergo intensive functional changes owing to modifications in their subunit composition (Carter et al. 1988, Watanabe et al. 1992, Monyer et al. 1994, Wenzel ...
... isoxazol-4-yl) propanoic acid (AMPA) and kainate (KA). During early stages of postnatal development glutamate receptors of NMDA and AMPA type undergo intensive functional changes owing to modifications in their subunit composition (Carter et al. 1988, Watanabe et al. 1992, Monyer et al. 1994, Wenzel ...
A Functional Role for Intra-Axonal Protein Synthesis during Axonal
... antibodies were used: FI TC -conjugated goat anti-mouse, donkey antihuman, and donkey anti-goat antibodies (1:400; Jackson ImmunoResearch, West Grove, PA), and Texas Red-conjugated goat anti-rabbit antibody (1:400; IC N Biochemicals, Costa Mesa, CA). Cultures were rinsed in PBS and then mounted with ...
... antibodies were used: FI TC -conjugated goat anti-mouse, donkey antihuman, and donkey anti-goat antibodies (1:400; Jackson ImmunoResearch, West Grove, PA), and Texas Red-conjugated goat anti-rabbit antibody (1:400; IC N Biochemicals, Costa Mesa, CA). Cultures were rinsed in PBS and then mounted with ...