Non Conservation of Function for the
... Cellular processes such as tissue differentiation are coordinated by the controlled expression of regulatory proteins that trigger specific gene expression programs. Implementation of a program depends on both transcriptional activators and also on transcriptional repressors. The Prdm1 gene encodes ...
... Cellular processes such as tissue differentiation are coordinated by the controlled expression of regulatory proteins that trigger specific gene expression programs. Implementation of a program depends on both transcriptional activators and also on transcriptional repressors. The Prdm1 gene encodes ...
A conserved sequence in calmodulin regulated spectrinassociated
... but no non-animal organism, or animals without tissues such as Trichoplax or sponge seem to have such proteins (Baines et al. 2009). The fruit fly orthologue of CAMSAP1 is encoded by the gene ssp4/patronin. This gene is required for normal mitotic spindle formation in S2 cells, potentially indicating ...
... but no non-animal organism, or animals without tissues such as Trichoplax or sponge seem to have such proteins (Baines et al. 2009). The fruit fly orthologue of CAMSAP1 is encoded by the gene ssp4/patronin. This gene is required for normal mitotic spindle formation in S2 cells, potentially indicating ...
Diversity of heterotrimeric G-protein γ subunits in plants | SpringerLink
... plant Gγ subunits. All tested type A and B Gγ genes have four exons and three introns within the coding region. The two middle exons were almost identical in size, reflecting the conservation of the central domain. The first and fourth exons demonstrated more variability, while the size of the three ...
... plant Gγ subunits. All tested type A and B Gγ genes have four exons and three introns within the coding region. The two middle exons were almost identical in size, reflecting the conservation of the central domain. The first and fourth exons demonstrated more variability, while the size of the three ...
Novel leader exons of the cyclic adenosine 3 ,5
... Generation of promoter constructs A 2.9 kb DNA fragment flanking exon θ1 was amplified from human genomic DNA (Roche Molecular Biochemicals) using Pfu polymerase and primers #3320 and #3321 (extending to position –173 relative to the start ATG in exon θ1). The product was digested with SstI (positio ...
... Generation of promoter constructs A 2.9 kb DNA fragment flanking exon θ1 was amplified from human genomic DNA (Roche Molecular Biochemicals) using Pfu polymerase and primers #3320 and #3321 (extending to position –173 relative to the start ATG in exon θ1). The product was digested with SstI (positio ...
Precursor of human adenovirus core polypeptide Mu targets the
... Mu–EGFP are excluded from adenovirus DNA-binding protein (DBP)-rich replication centres in adenovirus-infected cells. Surprisingly, we observed that cells in which preMu–EGFP (but not Mu–EGFP) is transiently expressed prior to or shortly after infection with Ad2 did not express late adenovirus genes ...
... Mu–EGFP are excluded from adenovirus DNA-binding protein (DBP)-rich replication centres in adenovirus-infected cells. Surprisingly, we observed that cells in which preMu–EGFP (but not Mu–EGFP) is transiently expressed prior to or shortly after infection with Ad2 did not express late adenovirus genes ...
Bacterial second messengers, cGMP and cdiGMP, in a quest for
... proved to have diguanylate cyclase activity that was upregulated by up to four-fold by cGMP. Thus, cGMP synthesized by XC_0250 interacts with the cNMP-binding domain of the diguanylate cyclase XC_0249 to stimulate c-di-GMP synthesis. Earlier, GGDEF domains have been seen linked to the primary sensor ...
... proved to have diguanylate cyclase activity that was upregulated by up to four-fold by cGMP. Thus, cGMP synthesized by XC_0250 interacts with the cNMP-binding domain of the diguanylate cyclase XC_0249 to stimulate c-di-GMP synthesis. Earlier, GGDEF domains have been seen linked to the primary sensor ...
medline:93194904
... the activity of a diverged octamer DNA motif present in its promoter. The CD20(B1) encodes a B cell-specific protein involved in the regulation of human B cell proliferation and differentiation. Studies with 5' deletion CD20 promoter-CAT constructs have previously revealed two regions of the promote ...
... the activity of a diverged octamer DNA motif present in its promoter. The CD20(B1) encodes a B cell-specific protein involved in the regulation of human B cell proliferation and differentiation. Studies with 5' deletion CD20 promoter-CAT constructs have previously revealed two regions of the promote ...
VLDL receptor
The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable homology with the members of this lineage. Discovered in 1992 by T. Yamamoto, VLDLR is widely distributed throughout the tissues of the body, including the heart, skeletal muscle, adipose tissue, and the brain, but is absent from the liver. This receptor has an important role in cholesterol uptake, metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, and neuronal migration in the developing brain. In humans, VLDLR is encoded by the VLDLR gene. Mutations of this gene may lead to a variety of symptoms and diseases, which include type I lissencephaly, cerebellar hypoplasia, and atherosclerosis.