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Accumulation of autophagic vacuoles and cardiomyopathy in LAMP
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP

A Sweet Synthesis - Department of Chemistry ::: CALTECH
A Sweet Synthesis - Department of Chemistry ::: CALTECH

... hemichordates are sister taxa, in which case some primitive echinoderms really did have gill slits, no longer apparent in modern forms. Likewise, the discovery6 that insects have a genetic system of dorso-ventral specification similar to that of vertebrates — only inverted — gave Geoffroy Saint-Hila ...
Purification and amino acid sequence of sakacin A, a
Purification and amino acid sequence of sakacin A, a

... activity was observed (results not shown). This indicates that the oxidation state of the cysteine residues may not be important for the bacteriocin activity. In contrast, the two cysteine residues of leucocin A-UAL 187 are thought to form a cystine bridge, although reduction without loss of activit ...
Molecular characterization of carnitinedependent transport of
Molecular characterization of carnitinedependent transport of

... glyoxylate cycle to produce succinate, which is subsequently transported to the mitochondria, probably via the putative dicarboxylate carrier, Acr1p (Palmieri et al., 1997). The second pathway involves the intraperoxisomal conversion of acetyl-CoA into acetylcarnitine, which is catalysed by carnitin ...
C3 receptors on macrophages - Journal of Cell Science
C3 receptors on macrophages - Journal of Cell Science

Late Endosomal/Lysosomal Targeting and Lack of Recycling of the
Late Endosomal/Lysosomal Targeting and Lack of Recycling of the

Glucagon receptor recycling: role of carboxyl terminus - AJP-Cell
Glucagon receptor recycling: role of carboxyl terminus - AJP-Cell

Gene Expression in Bone Cells
Gene Expression in Bone Cells

... my supervisor Dr Nigel Morrison for his guidance and his wisdom through out the course of PhD. I would also like to thank him for believing in me and trusting me to endeavour into new the area of research. Without his faith, I would have never been able to successfully complete a great PhD project a ...
A homozygous splicing mutation causing a
A homozygous splicing mutation causing a

multiple functions The ADAMs family of metalloproteases
multiple functions The ADAMs family of metalloproteases

Neutrophil-specific granule deficiency: homozygous recessive
Neutrophil-specific granule deficiency: homozygous recessive

- Bronco Scholar
- Bronco Scholar

... These impairments increase in severity until the individual loses the ability to talk, walk, or reason. Once these symptoms manifest they will progress until the patient becomes fully dependent on others, which can affect the family emotionally, socially, and economically (Huntington’s Disease Socie ...
2. Fredriksson, R., et al., The G-protein
2. Fredriksson, R., et al., The G-protein

Red Blood Cell Glycophorins
Red Blood Cell Glycophorins

... well-characterized, search for the protein encoded by this constitute a group of red blood cell (RBC) transmemgene has yielded negative results. All the expressed glycophbrane proteins that, although perhaps not widely appreciorins are 0-glycosylated proteins with their amino terminal ated in clinic ...
Full text PDF
Full text PDF

Red blood cell glycophorins
Red blood cell glycophorins

The distribution of SMN protein complex in human fetal tissues and
The distribution of SMN protein complex in human fetal tissues and

Hematopoietic cells expressing the peripheral cannabinoid receptor
Hematopoietic cells expressing the peripheral cannabinoid receptor

... Two distinct cannabinoid receptors have previously been identified: the central1 (Cb1) and the peripheral (Cb2) cannabinoid receptor.2 In retrovirally induced murine leukemia, proviral insertions frequently occur in the gene encoding Cb2, suggesting that the peripheral cannabinoid receptor is an onc ...
Two Domains of the Human bZIP Transcription Factor
Two Domains of the Human bZIP Transcription Factor

Dynamics of lipoprotein transport in the human circulatory system
Dynamics of lipoprotein transport in the human circulatory system

A 55-Kilodalton Accessory Factor Facilitates Vitamin D Receptor
A 55-Kilodalton Accessory Factor Facilitates Vitamin D Receptor

PDF - SAGE Journals
PDF - SAGE Journals

... and Bayliss 1968; Pitas et al. 1987; Agranoff et al. 1999; Dreissig et al. 2009). These differences between the brain and the periphery would, therefore, somewhat restrict the classic functions of LPL in the brain to those that are independent of TAG or apoB-containing lipoproteins. Brain lipoprotei ...
Leuprorelin rescues polyglutamine
Leuprorelin rescues polyglutamine

as a PDF
as a PDF

Inhibition of Phorbol Ester-Induced Monocytic
Inhibition of Phorbol Ester-Induced Monocytic

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VLDL receptor



The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable homology with the members of this lineage. Discovered in 1992 by T. Yamamoto, VLDLR is widely distributed throughout the tissues of the body, including the heart, skeletal muscle, adipose tissue, and the brain, but is absent from the liver. This receptor has an important role in cholesterol uptake, metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, and neuronal migration in the developing brain. In humans, VLDLR is encoded by the VLDLR gene. Mutations of this gene may lead to a variety of symptoms and diseases, which include type I lissencephaly, cerebellar hypoplasia, and atherosclerosis.
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