"Neurotransmitter Receptors in the Postsynaptic Neuron". In
... itself has structural (but not amino acid sequence!) homology to the protein bacteriorhodopsin, and homology with rhodopsin, the light-harvesting protein expressed in the eye. Metabotropic neurotransmitter receptors are, mostly, single subunit receptors. Each receptor has seven transmembrane-spannin ...
... itself has structural (but not amino acid sequence!) homology to the protein bacteriorhodopsin, and homology with rhodopsin, the light-harvesting protein expressed in the eye. Metabotropic neurotransmitter receptors are, mostly, single subunit receptors. Each receptor has seven transmembrane-spannin ...
Cellular uptake of fatty acids driven by the ER-localized acyl
... glucose has been shown to rely on membrane proteins creating a channel in the plasma membrane through which molecules enter the intracellular environment. However, the molecular mechanism for the transport of fatty acids across the plasma membrane has remained unresolved. Although there is general a ...
... glucose has been shown to rely on membrane proteins creating a channel in the plasma membrane through which molecules enter the intracellular environment. However, the molecular mechanism for the transport of fatty acids across the plasma membrane has remained unresolved. Although there is general a ...
Cell Metabolism
... suggesting that they are unable to efficiently mobilize stored fat for energy. Microarray studies support this model, indicating reduced expression of genes that control lipid catabolism and b-oxidation. A GAL4dHNF4;UAS-lacZ ligand sensor can be activated by starvation or exogenous long-chain fatty ...
... suggesting that they are unable to efficiently mobilize stored fat for energy. Microarray studies support this model, indicating reduced expression of genes that control lipid catabolism and b-oxidation. A GAL4dHNF4;UAS-lacZ ligand sensor can be activated by starvation or exogenous long-chain fatty ...
01 Endocrin Sys
... Hormone Transport in Blood • Protein hormones circulate in free form in blood • Steroid (lipid) & thyroid hormones must attach to transport proteins synthesized by liver – improve transport by making them water-soluble – slow loss of hormone by filtration within kidney – create reserve of hormone • ...
... Hormone Transport in Blood • Protein hormones circulate in free form in blood • Steroid (lipid) & thyroid hormones must attach to transport proteins synthesized by liver – improve transport by making them water-soluble – slow loss of hormone by filtration within kidney – create reserve of hormone • ...
1. Introduction Chemotaxis Chemotaxis is the net movement of a
... receptors, Tar and Tsr, along with Trg, Tap, and Aer. Tar allows cells to respond chemotactically to aspartate and maltose (when the sugar is bound to the periplasmic maltose binding protein, MBP) [27, 28], with relatively high affinity for aspartate at 3 µM in E. coli [29]. Several solved structure ...
... receptors, Tar and Tsr, along with Trg, Tap, and Aer. Tar allows cells to respond chemotactically to aspartate and maltose (when the sugar is bound to the periplasmic maltose binding protein, MBP) [27, 28], with relatively high affinity for aspartate at 3 µM in E. coli [29]. Several solved structure ...
Abscisic Acid–Induced Transcription Is Mediated by
... other plant species, three sequence blocks are found, designated regions I to III, that are highly conserved among these factors in the N-terminal region (Figure 1). The sequence comparison and examination of the genomic sequence corresponding to the TRAB1 gene obtained from the Syngenta draft seque ...
... other plant species, three sequence blocks are found, designated regions I to III, that are highly conserved among these factors in the N-terminal region (Figure 1). The sequence comparison and examination of the genomic sequence corresponding to the TRAB1 gene obtained from the Syngenta draft seque ...
The ErbB/HER receptor protein
... downstream signals, which often include the activation of protein-serine/threonine kinases. Amplification accounts for the high ratio of phosphoserine and phosphothreonine to phosphotyrosine in cells. ...
... downstream signals, which often include the activation of protein-serine/threonine kinases. Amplification accounts for the high ratio of phosphoserine and phosphothreonine to phosphotyrosine in cells. ...
Molecular mechanisms of copper homeostasis in yeast
... strated that the Fe-deficiency phenotypes of the Ctr1 mutants were the consequence of Cu deficiency and that Ctr1 is a Cu transporter. Indeed, Cu transported through Ctr1 serves as a cofactor of the Fet3 ferroxidase required for Fe uptake (Askwith et al. 1994). The mammalian Cu-containing ferroxidas ...
... strated that the Fe-deficiency phenotypes of the Ctr1 mutants were the consequence of Cu deficiency and that Ctr1 is a Cu transporter. Indeed, Cu transported through Ctr1 serves as a cofactor of the Fet3 ferroxidase required for Fe uptake (Askwith et al. 1994). The mammalian Cu-containing ferroxidas ...
G-protein-coupled receptor kinases
... either purified and reconstituted into phospholipid vesicles (3) or prepared as plasma membrane fractions from cells overexpressing receptor protein (4). More recently, cotransfection of cells with both epitope-tagged receptors and GRKs has allowed testing for effects of individual GRKs on receptor ...
... either purified and reconstituted into phospholipid vesicles (3) or prepared as plasma membrane fractions from cells overexpressing receptor protein (4). More recently, cotransfection of cells with both epitope-tagged receptors and GRKs has allowed testing for effects of individual GRKs on receptor ...
MECHANISMS OF INTERCELLULAR COMMUNICATION
... • BINDING USUALLY ACTIVATES CELLULAR PROCESSES • SOMETIMES BINDING INACTIVATES CELLULAR PROCESSES • DIRECT OR INDIRECT EFFECTS ...
... • BINDING USUALLY ACTIVATES CELLULAR PROCESSES • SOMETIMES BINDING INACTIVATES CELLULAR PROCESSES • DIRECT OR INDIRECT EFFECTS ...
VLDL receptor
The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR shows considerable homology with the members of this lineage. Discovered in 1992 by T. Yamamoto, VLDLR is widely distributed throughout the tissues of the body, including the heart, skeletal muscle, adipose tissue, and the brain, but is absent from the liver. This receptor has an important role in cholesterol uptake, metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, and neuronal migration in the developing brain. In humans, VLDLR is encoded by the VLDLR gene. Mutations of this gene may lead to a variety of symptoms and diseases, which include type I lissencephaly, cerebellar hypoplasia, and atherosclerosis.