Διαφάνεια 1 - Aristotle University of Thessaloniki
... Conditions associated with the immune system ...
... Conditions associated with the immune system ...
Immunity Ch. 11.1-6
... 11.2 The Complement System • Around 20 soluble proteins help destroy extracellular microorganisms • Produced by the liver & macrophages • Proteins bind to invaders (non-self) (opsonization) to identify them for destruction. ...
... 11.2 The Complement System • Around 20 soluble proteins help destroy extracellular microorganisms • Produced by the liver & macrophages • Proteins bind to invaders (non-self) (opsonization) to identify them for destruction. ...
Role of complement in health and disease
... • The complement system has the potential to be extremely damaging to host tissues, hence regulatory mechanisms are required to restrict the complement pathway. • Passive mechanism: highly labile components that undergo spontaneous inactivation if not stabilized by other components. • Active me ...
... • The complement system has the potential to be extremely damaging to host tissues, hence regulatory mechanisms are required to restrict the complement pathway. • Passive mechanism: highly labile components that undergo spontaneous inactivation if not stabilized by other components. • Active me ...
The Innate Immune Response PowerPoint
... move from plasma to interstitial spaces to provide an immediate defense ...
... move from plasma to interstitial spaces to provide an immediate defense ...
Hypersensitivity Reaction Types
... types, it is not antibody mediated but rather is a type of cell-mediated response. CD8 cytotoxic T cells and CD4 helper T cells recognise antigen in a complex with either type I or II major histocompatibility complex. The antigen-presenting cells in this case are macrophages and they release interle ...
... types, it is not antibody mediated but rather is a type of cell-mediated response. CD8 cytotoxic T cells and CD4 helper T cells recognise antigen in a complex with either type I or II major histocompatibility complex. The antigen-presenting cells in this case are macrophages and they release interle ...
Non specific defense mechanisms of fish
... • The organism needs to defend itself not only from pathogens that are outside the body, such as bacteria, viruses etc but also from abnormal cells within the body which can give rise to cancers. ...
... • The organism needs to defend itself not only from pathogens that are outside the body, such as bacteria, viruses etc but also from abnormal cells within the body which can give rise to cancers. ...
MICROBIO320 Short Answers – These should be typically 1
... Complete the following Diagram of B Cell DNA Gene rearrangement (4 pts) The final Mature B cell will display IgA1 immunoglobulin with V3D1J2 specificity. How many individual rearrangement steps will be required to produce this heavy chain? ...
... Complete the following Diagram of B Cell DNA Gene rearrangement (4 pts) The final Mature B cell will display IgA1 immunoglobulin with V3D1J2 specificity. How many individual rearrangement steps will be required to produce this heavy chain? ...
Engineered Human Cells: SAY NO TO SEPSIS
... High mortality rate ~40% No novel advances since 1980s Associated mainly with gram-negative bacteremia Dysregulated release of chemokines (including cytokines) Additional injury due to endotoxins: Coagulation cascade Complement cascade Vessel injury Release of prostaglandins Eventually lea ...
... High mortality rate ~40% No novel advances since 1980s Associated mainly with gram-negative bacteremia Dysregulated release of chemokines (including cytokines) Additional injury due to endotoxins: Coagulation cascade Complement cascade Vessel injury Release of prostaglandins Eventually lea ...
Title goes here
... MHC-like molecules (CD1d) on antigen presenting cells present glycolipids to NK T cells with an invariant T cell receptor ...
... MHC-like molecules (CD1d) on antigen presenting cells present glycolipids to NK T cells with an invariant T cell receptor ...
ANTIBODY PRODUCTION
... Antigens from the ruined pathogen are displayed on the surface of the phagocyte (or B-cell), bound to a membrane called MHC protein. This combination of antigen and MHC attracts the help of a mature, matching Helper T Cell. ...
... Antigens from the ruined pathogen are displayed on the surface of the phagocyte (or B-cell), bound to a membrane called MHC protein. This combination of antigen and MHC attracts the help of a mature, matching Helper T Cell. ...
CDSA: Immunopathology
... A 30-year-old female complains of increasing prominence of the front of her neck. She admits to being nervous about many things lately and preferred to have the air-conditioner set at a very cool setting because she could not stand the heat. She however was happy about staying slender in spite of he ...
... A 30-year-old female complains of increasing prominence of the front of her neck. She admits to being nervous about many things lately and preferred to have the air-conditioner set at a very cool setting because she could not stand the heat. She however was happy about staying slender in spite of he ...
Types II and III: Antibody-Mediated and Antigen
... Goodpasture syndrome is a rare disease that can involve rapidly progressive kidney failure along with lung disease. However, some forms of the disease involve just the lung or kidney, not both. Causes, incidence, and risk factors Goodpasture syndrome is an autoimmune disorder, a condition that occur ...
... Goodpasture syndrome is a rare disease that can involve rapidly progressive kidney failure along with lung disease. However, some forms of the disease involve just the lung or kidney, not both. Causes, incidence, and risk factors Goodpasture syndrome is an autoimmune disorder, a condition that occur ...
Other Players in the IMMUNE RESPONSE
... immunoglobin. Produced by the B cells. An effector of the immune response. • Antigen—ANTIbody GENerator. A foreign macromolecule that elicits an immune response. • The specificity between the shapes of antigens and antibodies are the basis of the immune response. ...
... immunoglobin. Produced by the B cells. An effector of the immune response. • Antigen—ANTIbody GENerator. A foreign macromolecule that elicits an immune response. • The specificity between the shapes of antigens and antibodies are the basis of the immune response. ...
DEFINING HYPERSENSITIVITY
... Immune (Ag-Ab) complexes promote tissue damage primarily through complement activation (alternate pathway). C3b as an opsonin attracts neutrophils, which then release lysosomal enzymes. C5a as a chemoattractant brings in neutrophils. Serum complement is reduced as it is used up in this process. Anti ...
... Immune (Ag-Ab) complexes promote tissue damage primarily through complement activation (alternate pathway). C3b as an opsonin attracts neutrophils, which then release lysosomal enzymes. C5a as a chemoattractant brings in neutrophils. Serum complement is reduced as it is used up in this process. Anti ...
Immune Response
... called histamines These cause increased blood flow (which causes swelling) to get more white blood cells WBCs attack pathogens Lymph nodes may also swell with fluid when they fight infection ...
... called histamines These cause increased blood flow (which causes swelling) to get more white blood cells WBCs attack pathogens Lymph nodes may also swell with fluid when they fight infection ...
Activators - U of M wiki
... mannose that are present in the cell wall polysaccharides of microorganisms such as Salmonella, Listeria, Neisseria, Candida, etc. MBL, which resembles C1q, interacts with MASP-1 and MASP-2 by a mechanism similar to C1q interaction with C1r and C1s, resulting in the formation of the classical path ...
... mannose that are present in the cell wall polysaccharides of microorganisms such as Salmonella, Listeria, Neisseria, Candida, etc. MBL, which resembles C1q, interacts with MASP-1 and MASP-2 by a mechanism similar to C1q interaction with C1r and C1s, resulting in the formation of the classical path ...
Hadassah University Hospital
... (T-lymphocytes and its subgroups) Humoral immunity component (Blymphocytes and its product antibodies) ...
... (T-lymphocytes and its subgroups) Humoral immunity component (Blymphocytes and its product antibodies) ...
Power Point
... The complement system (Abbr. C): • A group of proteins present in the plasma of all individuals. Part of the innate immune system. • A major biological effector system of both the innate and the adaptive immune responses. • The C components are present in the plasma in an inactive state. • Upon acti ...
... The complement system (Abbr. C): • A group of proteins present in the plasma of all individuals. Part of the innate immune system. • A major biological effector system of both the innate and the adaptive immune responses. • The C components are present in the plasma in an inactive state. • Upon acti ...
Serum Sickness
... Serum sickness is a reaction similar to an allergy. Specifically, type III hypersensitivity reaction to certain medications, injected proteins used to treat immune conditions, or antiserum ▪ Antiserum: liquid part of blood that contains antibodies that help protect against infectious or poisonous ...
... Serum sickness is a reaction similar to an allergy. Specifically, type III hypersensitivity reaction to certain medications, injected proteins used to treat immune conditions, or antiserum ▪ Antiserum: liquid part of blood that contains antibodies that help protect against infectious or poisonous ...
Complement system
The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.