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Immunoglobulins
Immunoglobulins

... • Immunoglobulins must interact with a small number of specialized molecules : - Fc receptors on cells ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 9. A vaccine contains antibodies that stimulate adaptive immunity to a disease. 10. ELISA is a test used to confirm the presence of foreign DNA. III. Complete the following: ...
Chapter 14: Resistance and the Immune System: Innate Immunity
Chapter 14: Resistance and the Immune System: Innate Immunity

Evolution of Immune Systems
Evolution of Immune Systems

... • Porifera have polymorphic ‘MHC genes” with multiple loci • MHC have no structural similarities to vertebrate MHC - proteoglycan complex ...
الرقم : بدون التاريخ : 08/ 11 / 1427
الرقم : بدون التاريخ : 08/ 11 / 1427

File - Biology with Radjewski
File - Biology with Radjewski

...  Don’t dissolve well in watery blood plasma, so they circulate to carrier proteins ...
tib4handout
tib4handout

... 1) destroying the virus 2) destroying the virus-infected host cell 3) 3) protecting uninfected cells from becoming infected with viruses. ...
Inflammatory Immune Response
Inflammatory Immune Response

Type II Hypersensitivity: Antibody mediated cytotoxicity
Type II Hypersensitivity: Antibody mediated cytotoxicity

... • Both processes result in lysis of the Ab-coated cell • Clinical examples of Type II responses include: – Certain autoimmune diseases where Ab’s produced vs membrane Ag’s • Grave’s Disease – Ab’s produced vs thyroid hormone receptor • Myasthenia Gravis – Ab’s produced vs acetylcholine recpetors • A ...
Physiology of the Blood III. White Blood Cells and the Immune
Physiology of the Blood III. White Blood Cells and the Immune

03-390 Immunology Exam I - 2014 Name:_____________________
03-390 Immunology Exam I - 2014 Name:_____________________

041201 Complement — Second of Two Parts
041201 Complement — Second of Two Parts

... onto antibodies within these immune complexes. In this way, C1q acts to bridge the innate and adaptive immune systems. Complement also has an important role in the induction of antibody responses.62 This was shown first by Pepys, who demonstrated that the formation of antibodies against T-cell–depen ...
The Immune System 2
The Immune System 2

... The Immune System 2 ...
Another person Direct contact: shaking hands 1. 2. Contaminated
Another person Direct contact: shaking hands 1. 2. Contaminated

... 9. Define and give an example of “pathogens”. ...
+ the statement is correct - the statement isn´t correct 1. Out of the
+ the statement is correct - the statement isn´t correct 1. Out of the

... 2) - Lectin pathway of complement activation is initiated by the binding of serum lectin (MBL) to proteins derived from microorganisms 3) - Cytoplasmic membrane of human cells is composed of strongly amphipathic components, which cause a stronger interaction between membrane molecules, thus preventi ...
Innate immune recognition
Innate immune recognition

... 1. Antigen (Ag) receptors on T & B lymphocytes. 2. These Ag receptors generated by somatic gene ...
Autoimmune Diseases
Autoimmune Diseases

... Multiple elements of the immune system may be disrupted (including complement, with opportunistic infections). Incidence ~40 / 100 000. Antinuclear antibodies (ANA), against dsDNA (fluctuanting with flare-ups), and against small ribonucleoproteins (snRNPs, like Smith -Sm- antigen) exposed by cell ne ...
Innate Immune Response
Innate Immune Response

A “Y”
A “Y”

... Antigens that are generated within cells of the body Proteins encoded by the genes of viruses (foreign) Abnormal or altered proteins -Encoded by mutant genes (e.g. mutated proteins produced by cancer cells) ...
ELISA Pre and Post Test
ELISA Pre and Post Test

... 1. Disease-causing agents such as viruses, bacteria, protozoa, molds and other microorganisms are called: a. antibodies; b. antigens; c. pathogens; d. microgens. 2. Your skin, respiratory system, digestive system, and circulatory system represent: a. first line defenses; b. nonspecific immunities; c ...
Objectives 13
Objectives 13

Lines of Defense and Immunity
Lines of Defense and Immunity

... Consists of 26 blood proteins that work in concert to destroy bacteria and viruses Complement proteins are activated by cleavage Classical pathway Alternative pathway ...
Document
Document

... The Complement System • Serum proteins activated in a cascade • Activated via one of three pathways • Activated Complement proteins trigger 3 primary immune responses ...
File - Pomp
File - Pomp

... • 60-70% WBCs; engulf and destroy microbes at infected tissue Short lived • Monocytes • 5% WBCs; develop into…. – Macrophages 1)phagocytosis – 2)lysosomal enzymes destroy microbes ...
Immune and Autoimmune Responses to cytosolic
Immune and Autoimmune Responses to cytosolic

< 1 ... 102 103 104 105 106 107 108 109 110 ... 115 >

Complement system



The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.
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