Download + the statement is correct - the statement isn´t correct 1. Out of the

+ the statement is correct
- the statement isn´t correct
1. Out of the following choose correct statements
1) - Neutrophils survive in the connective tissue for several weeks
2) - Average size of an erythrocyte is 9 µm
3) - Central part of platelets containing coagulation factors is called a hyalomere
4) + Eosinophilia (increased number of eosinophils in blood) is associated with
allergic reactions and parasitic infections
-----------------------------------------------------------------------------------------2. Choose true statements
1) + During routine processing of histological sections lipids are washed out of cells
2) + Tumour cells can be detected thanks to tumour-specific antigens
3) - Heidenhein iron hematoxylin is not used for heart muscle staining
4) - Immunohistochemistry enables us to detect only proteins present in the
plasmalemma
-----------------------------------------------------------------------------------------3. Which of the following statements are true?
1) + separation during capillary zone electrophoresis is based on a different mobility
of individual analytes
2) - two mutually miscible phases are used in a chromatography: a stationary and a
mobile phase
3) + potentiometry is based on measuring of an electrode potential difference under
no current flow conditions
4) - height of a peak is used for the qualitative analysis of a chromatogram in
chromatography
-----------------------------------------------------------------------------------------4. Which of the following is correct?
1) - Somatic hypermutation occurs after antigen recognition by mature T cell
2) + Antibodies able to activate complement are generated during the first phase of
antibody response (primary response)
3) + Help of Th2 cells to B cells is mediated by IL-4, IL-5, IL-6 and direct cell-to-cell
contact
4) + IgG is the most abundant serum immunoglobulin
-----------------------------------------------------------------------------------------5. Which of the following is correct?
1) - methemoglobin has a higher affinity to oxygen than hemoglobin
2) - carbonylhemoglobin contains heme-bound ferric ions
3) - carbaminohemoglobin is a patological form of hemoglobin
4) + carbonic acid is formed in erythrocytes in a reaction catalyzed by carbonic
anhydrase
------------------------------------------------------------------------------------------
6. Out of the following choose correct statements
1) + Isotype switching is present during the development of B cells
2) + Creation of B cell clones with different B receptors is accompanied by a rise of
autoreactive clones
3) - Enzyme called terminal phosphatidyl transferase is involved in immunoglobulin
heavy chain gene rearrangement
4) + VDJ rearrangement (recombination) does not always produce a functional
immunoglobulin heavy chain
-----------------------------------------------------------------------------------------7. Select correct statements
1) - haem is synthesised from propionyl-CoA and glycine
2) - porphobilinogen is a porphyrin
3) + lower pH decreases the affinity of transferrin for iron
4) - gene for the transferrin receptor has an IRE (iron response element) at the 5'
end
-----------------------------------------------------------------------------------------8. Which of the following is correct?
1) - Intercalated disk is a subunit of a sarcomere
2) - Myoglobin is involved in myosin phosphorylation during contraction
3) + Smooth muscle cells are able to synthesise collagen, elastin and proteoglycans
4) + During smooth muscle contraction the cell nucleus is squeezed into a corkscrew
shape or a spiral
-----------------------------------------------------------------------------------------9. Select correct statements
1) + vitamin K is important for the synthesis of both coagulation factors and
anticoagulant factors
2) - Ca2+ decreases the rate of coagulation
3) + von Willebrand factor binds platelets to collagen and also platelets together
4) + intrinsic tenase complex contains factors IXa and VIIIa, platelet phospholipids
and Ca2+
-----------------------------------------------------------------------------------------10. Which of the following is correct?
1) + T cells regulate immune responses
2) - NKT cells recognize complexes of antigens with HLA II molecules
3) - Differentiation of Th cell precursors into mature Th1 lymphocytes depends on
the secretion of IL-4
4) + NKT cells recognize complexes of antigens with CD1 molecules
-----------------------------------------------------------------------------------------11. Out of the following choose correct statements
1) - Agglutination is measured by nephelometry
2) - In flow cytometric analysis CD20 and CD3 markers are frequently found on the
same cellular population
3) + Flow cytometry is based on the binding of monoclonal antibodies conjugated
with a fluorochrome to a membrane marker
4) + Flow cytometry is based on the changes of laser light due to the size and
granularity of analysed particles
12. Select correct statements
1) + Phagocytes express scavenger receptors on their surface
2) + Scavenger receptors recognize apoptotic cell
3) - Antibodies can act as chemotaxins
4) + IgG Fc receptors (Fc gamma RI, Fc gamma RII and Fc gamma RIII) have
different binding affinities to the IgG Fc fragment
-----------------------------------------------------------------------------------------13. Select correct statements
1) + in the determination of protein concentration bovine serum albumin (BSA) can
be used for the preparation of a calibration curve
2) - during SDS-PAGE proteins move towards the negative electrode
3) - Western blot is routinely used for a determination of amino acid sequences in
unknown proteins
4) - absorption of proteins in the UV part of the spectrum only occurs after a reaction
with the Bradford reagent
-----------------------------------------------------------------------------------------14. Choose true statements
1) + MALT, diffuse lymphoid tissue, is present in the loose connective tissue of the
lamina propria of mucosa layer
2) + B lymphocytes differentiate into plasma cells
3) - Follicular dendritic cells differentiate from myeloid precursors in the bone marrow
4) - Dendritic cells originate from lymphoid precursors
-----------------------------------------------------------------------------------------15. Select correct statements
1) - glutamate is the most abundant amino acid in plasma
2) + cholesterol exists in lipoproteins in two forms: free and esterified
3) + consequences of changes in kalemia (blood K+ concentration) can be detected
on ECG
4) + plasma concentration of LDL-cholesterol should be lower than 3.0 mmol/l
-----------------------------------------------------------------------------------------16. Out of the following choose correct statements
1) + Mannan binding lectin (MBL) has a similar structure to one of the subunits of the
C1 complement component
2) - Lectin pathway of complement activation is initiated by the binding of serum
lectin (MBL) to proteins derived from microorganisms
3) - Cytoplasmic membrane of human cells is composed of strongly amphipathic
components, which cause a stronger interaction between membrane molecules, thus
preventing the insertion of complement component C3b
4) + C3-convertase of alternative pathway is formed from C3b and factor Bb
------------------------------------------------------------------------------------------
17. Select correct statements
1) + Crossmatch testing during organ transplantations consists of the testing of a
recipient's HLA antibodies against donor’s HLA molecules
2) + T lymphocyte receptor has a cytoplasmic, transmembrane and extracellular part
of its molecule
3) - After activation B lymphocytes undergo only clonal expansion; their receptors do
not undergo any changes
4) + Non-classical antigens of MHC class one (E, F, G) are present only on the
surface of certain tissues
-----------------------------------------------------------------------------------------18. Out of the following choose correct statements
1) + MHC class II glycoproteins consist of one a-chain and one b-chain
2) + In the endoplasmic reticulum a- and b-chains of MHC class II molecules first
bind an Ii invariant chain
3) - Expression of classic MHC class I molecule HLA-G is limited to placental
trophoblast
4) + MHC class III genes encode some complement components, stress proteins
and the cytokine TNF
-----------------------------------------------------------------------------------------19. Which of the following is correct?
1) - arachidonic acid is usually situated in the first position in phospholipids (further
form the phosphate group)
2) - bleeding in the gastrointestinal tract is a typical side effect of selective COX-2
inhibitors
3) + low doses of aspirin are used in the prevention of myocardial infarction
4) + leukotrienes are synthesized from hydroperoxyeicosatetraenoic acid (HPETE)
-----------------------------------------------------------------------------------------20. Select correct statements
1) + Innate immunity closely cooperates with adaptive immunity
2) - Mast cells differentiate into different subtypes only after being influenced by the
microenvironment
3) - Innate immunity has immunological memory
4) + Eosinophils are activated by IL-5