![Chapter 14: Resistance and the Immune System: Innate Immunity](http://s1.studyres.com/store/data/010115527_1-36736189c6253b8fdde5e363aaa0d3f1-300x300.png)
Chapter 14: Resistance and the Immune System: Innate Immunity
... • Opsonins attach to microbes to increase the ability of phagocytes to adhere (opsonization) • Phagocytized microbes are held in a phagosome • The phagosome is acidified, killing or inactivating the pathogen • Phagosomes also fuse with lysosomes (phagolysosome) • Enzymes and other products kill and ...
... • Opsonins attach to microbes to increase the ability of phagocytes to adhere (opsonization) • Phagocytized microbes are held in a phagosome • The phagosome is acidified, killing or inactivating the pathogen • Phagosomes also fuse with lysosomes (phagolysosome) • Enzymes and other products kill and ...
Humoral components and cellular mechanisms, such as
... The innate immune system consists of humoral components, such as complement, and cellular mechanisms, such as phagocytosis. This pathway directs the adaptive immune response. For example, the innate immune system mediates clearance of apoptotic cells without initiating adaptive immunity, a process w ...
... The innate immune system consists of humoral components, such as complement, and cellular mechanisms, such as phagocytosis. This pathway directs the adaptive immune response. For example, the innate immune system mediates clearance of apoptotic cells without initiating adaptive immunity, a process w ...
MCB50 Immunity and Disease 1 Bacteria Lecture Outline March 2
... clinically and on isolation of the bacteria from a throat swab. 2. Scarlet fever This disease results from the release of toxic substances by S. pyogenes. If it occurs, it is usually associated with Streptococcal throat infections. It is associated with a rash which appears as a diffuse red blush wi ...
... clinically and on isolation of the bacteria from a throat swab. 2. Scarlet fever This disease results from the release of toxic substances by S. pyogenes. If it occurs, it is usually associated with Streptococcal throat infections. It is associated with a rash which appears as a diffuse red blush wi ...
Ch. 43 - Immune System
... phagocyte found throughout your body) enter and eat the invaders (called antigens); this causes swelling. Macrophages secrete lysosomes into the antigen to destroy it; problem – it will attack anything not us, including organ transplants ...
... phagocyte found throughout your body) enter and eat the invaders (called antigens); this causes swelling. Macrophages secrete lysosomes into the antigen to destroy it; problem – it will attack anything not us, including organ transplants ...
Slide 1
... A set of physiological reactions to damage of tissue integrity, leading to protection against infection, localization and restriction of the damaged site and finally to healing. ...
... A set of physiological reactions to damage of tissue integrity, leading to protection against infection, localization and restriction of the damaged site and finally to healing. ...
Rapid response to infection
... substances • Tears, saliva, mucous: Contain lysozyme • “Friendly Bacteria”: Take space & resources, produce acids ...
... substances • Tears, saliva, mucous: Contain lysozyme • “Friendly Bacteria”: Take space & resources, produce acids ...
INTEGUMENTARY SYSTEM - Coast Colleges Home Page
... Antigen-specific (relies on recognition of foreign antigens) Systemic (body-wide) Memory (stronger future immune response) 2 types of Immune Response: - Humoral (Antibody-Mediated) - Cellular (Cell-Mediated) ...
... Antigen-specific (relies on recognition of foreign antigens) Systemic (body-wide) Memory (stronger future immune response) 2 types of Immune Response: - Humoral (Antibody-Mediated) - Cellular (Cell-Mediated) ...
Inflammation 1
... Inflammation is a protective response involving host cells, blood vessels, proteins and other mediators intended to eliminate the initial cause of cell injury, as well as the necrotic cells and tissues resulting from the original insult, and to initiate the process of repair. ...
... Inflammation is a protective response involving host cells, blood vessels, proteins and other mediators intended to eliminate the initial cause of cell injury, as well as the necrotic cells and tissues resulting from the original insult, and to initiate the process of repair. ...
introduction to the immune system
... 1. directly attack invaders and lyse body cells infected by viruses or other intracellular parasites, cancer cells, foreign grafts 2. release chemicals that enhance the inflammatory response or help to activate lymphocytes or macrophages. Densest populations of lymphocytes: 1. bone marrow 2. thymus ...
... 1. directly attack invaders and lyse body cells infected by viruses or other intracellular parasites, cancer cells, foreign grafts 2. release chemicals that enhance the inflammatory response or help to activate lymphocytes or macrophages. Densest populations of lymphocytes: 1. bone marrow 2. thymus ...
Lymph capillaries, Lymphatic collecting vessels, Valves, Lymph Duct
... A student nurse receives an injection of gamma globin after she has been exposed to viral hepatitis “Borrowed” immunity ...
... A student nurse receives an injection of gamma globin after she has been exposed to viral hepatitis “Borrowed” immunity ...
Mechanism for Cell-Mediated Immunity Macrophage Activation as
... using L. monocytogenes, Brucella abortus, and Mycobacterium tuberculosis, Mackaness demonstrated that these activated macrophages have nonspecific resistance to unrelated pathogens, but only when cellular immunity has been established in vivo (3). This resistance was due to enhanced nonspecific bact ...
... using L. monocytogenes, Brucella abortus, and Mycobacterium tuberculosis, Mackaness demonstrated that these activated macrophages have nonspecific resistance to unrelated pathogens, but only when cellular immunity has been established in vivo (3). This resistance was due to enhanced nonspecific bact ...
Document
... 6. Fc receptors come in two basic types: activating (ITAM-associated) and inhibitory (ITIM-associated). 7. The relative expression of activating and inhibitory Fc receptors determines the outcome of a given engagement of Fc receptors. 8. Fc receptor-driven pathology includes formation and deposition ...
... 6. Fc receptors come in two basic types: activating (ITAM-associated) and inhibitory (ITIM-associated). 7. The relative expression of activating and inhibitory Fc receptors determines the outcome of a given engagement of Fc receptors. 8. Fc receptor-driven pathology includes formation and deposition ...
Lymphatic system Lecture #2
... – Depends on actions of several types of T cells – Antibodies are not produced, instead they directly attack foreign cells that carry antigens – Other T cells release proteins to coordinate other actions of the immune response: T cells, B cells and macrophages – Protects against parasites, bacteria, ...
... – Depends on actions of several types of T cells – Antibodies are not produced, instead they directly attack foreign cells that carry antigens – Other T cells release proteins to coordinate other actions of the immune response: T cells, B cells and macrophages – Protects against parasites, bacteria, ...
Reading Guide-InnateImmune (CH15)
... proteins are activated). Some really virulent pathogens have evolved mechanism to evade the process of phagocytosis…can you think of some ways in which an organism could evade phaogcytosis? Cells of the immune system need to be connected and communicating with each other to coordinate complex respon ...
... proteins are activated). Some really virulent pathogens have evolved mechanism to evade the process of phagocytosis…can you think of some ways in which an organism could evade phaogcytosis? Cells of the immune system need to be connected and communicating with each other to coordinate complex respon ...
16. The Body`s Line of Defence
... the bone marrow Agranulocytes are also produced in the bone marrow but are modified in the lymph nodes When a foreign particle penetrates the skin through an injury, special leukocytes, called monocytes migrate from the blood into the tissues where they develop into macrophages, which use phagocytos ...
... the bone marrow Agranulocytes are also produced in the bone marrow but are modified in the lymph nodes When a foreign particle penetrates the skin through an injury, special leukocytes, called monocytes migrate from the blood into the tissues where they develop into macrophages, which use phagocytos ...
Dinasil
... 100% safe and non toxic. Will not over stimulate the immune system nor will it elicit an anti-immune response Will not interfere with other medication being concurrently administered. Very easy to apply ...
... 100% safe and non toxic. Will not over stimulate the immune system nor will it elicit an anti-immune response Will not interfere with other medication being concurrently administered. Very easy to apply ...
Lecture 9 - University of Arizona | Ecology and
... • Bacteria colonize your body and modify their environment to prevent colonization by other microbes. • Change in pH (skin, genital tract, etc.) ...
... • Bacteria colonize your body and modify their environment to prevent colonization by other microbes. • Change in pH (skin, genital tract, etc.) ...
Immune System
... Foreign antigens bind to antibodies on B-cells Antigen-antibody complex stimulation Stimulated B-cell will produce/release this specific antibody as free floating antibody 5. Free floating antibodies will bind to all other antigens of the same type 6. Macrophages recognize antibodies and phagocytosi ...
... Foreign antigens bind to antibodies on B-cells Antigen-antibody complex stimulation Stimulated B-cell will produce/release this specific antibody as free floating antibody 5. Free floating antibodies will bind to all other antigens of the same type 6. Macrophages recognize antibodies and phagocytosi ...
LACZIK_Pharmacology - 3.practice
... Leading causes of death worldwide. About 15 million (>25%) of 57 million annual deaths worldwide are the direct result of infectious disease. Figures published by the World Health Organization (see http://www.who.int/whr/en and ref.7). ...
... Leading causes of death worldwide. About 15 million (>25%) of 57 million annual deaths worldwide are the direct result of infectious disease. Figures published by the World Health Organization (see http://www.who.int/whr/en and ref.7). ...
PDF - Bentham Open
... autoimmune skin disease characterised by hyperplasia of epidermal keratinocytes and the accumulation of activated immune cells at sites of the disease. The disease is associated with aberrant activation of phagocytes (such as macrophages), Tlymphocytes and the production of pro-inflammatory cytokine ...
... autoimmune skin disease characterised by hyperplasia of epidermal keratinocytes and the accumulation of activated immune cells at sites of the disease. The disease is associated with aberrant activation of phagocytes (such as macrophages), Tlymphocytes and the production of pro-inflammatory cytokine ...
Researchers Learn How to Turn Cancer Cells into
... proceed to differentiate into dendritic cells and macrophages. Macrophages function mainly by engulfing foreign substances, cellular debris, microbial and cancer cells in a process termed phagocytosis. Key macrophage abilities include: 1. Increasing and decreasing the inflammatory response through m ...
... proceed to differentiate into dendritic cells and macrophages. Macrophages function mainly by engulfing foreign substances, cellular debris, microbial and cancer cells in a process termed phagocytosis. Key macrophage abilities include: 1. Increasing and decreasing the inflammatory response through m ...
01 Reticuloendothelial S and Spleen lecture 1433
... Stay for 10-20 hours in circulation Then leave blood to tissues transforming into larger cells macrophage, Macrophage life span is longer up to few months in tissues ...
... Stay for 10-20 hours in circulation Then leave blood to tissues transforming into larger cells macrophage, Macrophage life span is longer up to few months in tissues ...
12 inflammation
... signals induces rapid response, during which leukocytes, plasma proteins and fluid move into the site of inflammation. Beside macrophages, neutrophil granulocytes, IL -12 activated NK cells, and monocytes (exit from the circulation and differentiate to tissue macrophages) are the most important cell ...
... signals induces rapid response, during which leukocytes, plasma proteins and fluid move into the site of inflammation. Beside macrophages, neutrophil granulocytes, IL -12 activated NK cells, and monocytes (exit from the circulation and differentiate to tissue macrophages) are the most important cell ...
Statins as protective agents for aortic endothelial cells - wv
... formation of plaques reactive oxygen species (ROS) and Cytokines (TNFα, CRP, IL-6) recruit more inflammatory cells into the newly formed plaques increase lipid migration into the formed plaque ...
... formation of plaques reactive oxygen species (ROS) and Cytokines (TNFα, CRP, IL-6) recruit more inflammatory cells into the newly formed plaques increase lipid migration into the formed plaque ...
Macrophage
![](https://commons.wikimedia.org/wiki/Special:FilePath/Macrophage.jpg?width=300)
Macrophages (Greek: big eaters, from makros ""large"" + phagein ""eat""; abbr. MΦ) are a type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, cancer cells, and anything else that does not have the types of proteins specific to the surface of healthy body cells on its surface in a process called phagocytosis. Macrophages were first discovered by Élie Metchnikoff, a Russian bacteriologist, in 1884. They are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. They play a critical role in non-specific defense (innate immunity), and also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune cells such as lymphocytes. In humans, dysfunctional macrophages cause severe diseases such as chronic granulomatous disease that result in frequent infections.Beyond increasing inflammation and stimulating the immune system, macrophages also play an important anti-inflammatory role and can decrease immune reactions through the release of cytokines. Macrophages that encourage inflammation are called M1 macrophages, whereas those that decrease inflammation and encourage tissue repair are called M2 macrophages. This difference is reflected in their metabolism, M1 macrophages have the unique ability to metabolize arginine to the ""killer"" molecule nitric oxide, whereas M2 macrophages have the unique ability to metabolize arginine to the ""repair"" molecule ornithine.Human macrophages are about 21 micrometres (0.00083 in) in diameter and are produced by the differentiation of monocytes in tissues. They can be identified using flow cytometry or immunohistochemical staining by their specific expression of proteins such as CD14, CD40, CD11b, CD64, F4/80 (mice)/EMR1 (human), lysozyme M, MAC-1/MAC-3 and CD68.