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Transcript
WLHS/A&P/Oppelt
Name ______________________
Lymphatic System Practice
1. Figure 12-1 provides an overview of the lymphatic vessels. First color code the following structures.
Color code in Figure 12-1
Heart
Veins
Lymphatic vessels/lymph nodes
Arteries
Blood capillaries
Loose connective tissue around blood and lymph
capillaries
Identify in Figure in 12-1
Lymph capillaries, Lymphatic collecting vessels, Valves, Lymph Duct, Lymph node, Vein
2. Circle the term that DOES NOT belong in each of the following groups.
a. blood capillary
b. edema
lymph capillary
blockage of lymphatics
c. Neutrophils
Macrophages
d. Redness
Pain
e. Inflammatory chemicals
blind-ended
permeable to protein
inflammation
abundant supply of lymphatics
Phagocytes
Natural Killer Cells
Swelling
Itching
Heat
Histamine
Kinins
Interferons
f. Intact skin
Intact mucosae
g. Interferons
Antiviral
Inflammation
Antibacterial
First line of defense
Proteins
3. Match the terms with the correct descriptions. More than one choice may apply.
1.
A blood reservoir
A. Lymph nodes
2.
Monitor composition of lymph
B. Peyer’s patches
3.
Located between the lungs at the base of the throat
C. Spleen
4.
Collectively called MALT
D. Thymus
5.
Prevents bacteria from breaching the intestinal wall
E. Tonsils
6.
The largest lymphatic organ
7.
Filter lymph
8.
9.
Particularly large and important during youth; helps to
program T cells of the immune system
Found in the wall of the gastrointestinal tract
10.
Removes aged and defective red blood cells
4. In Figure 12-3, identify the following structures of a lymph node:
Germinal centers of follicles
Medullary cords
Efferent lymphatics
Hilum
Capsule and trabeculae
Cortex (other than germinal centers)
Afferent lymphatics
Sinuses (subcapsular and medullary)
5. Figure 12-4 diagrams the events involved in the inflammatory response. Assume the following events have
already occurred: tissue injury and invasion of microbes, and release of inflammatory chemicals by mast cells.
Each subsequent is represented by a square with one or more arrows. From the list below, write the correct
number in each even square in the figure. Then, color-code the structures that appear below the numbered
list.
1. WBCs are drawn to the injured area by the release of inflammatory chemicals
2. Tissue repair occurs
3. Local blood vessels dilate, and the capillaries become engorged with blood.
4. Phagocytosis of microbes occurs.
5. Fluid containing clotting protins is lost from the bloodstream and enters the injured
tissue area.
6. Diapedesis occurs
Identify the following in the figure:
monocyte, epithelium, erythrocyte(s),
neutrophil(s), macrophage, subcutaneous
tissue, endothelium capillary,
microorganisms, fibrous tissue repair.
6. Match the term with the correct description of the nonspecific defenses of the body. More than one
choice may apply.
1.
Have antimicrobial activity
A. Acids
2.
Provide mechanical barriers
B. Lysozyme
3.
Provide chemical barriers
C. Mucosae
4.
Entraps microorganisms entering the
respiratory passages
D. Mucus
5.
Part of the first line of defense
E. Protein-digesting enzymes
F. Sebum
G. Skin
7. Check (√ ) all phrases that correctly describe the role of fever in body protection.
___ 1. Is a normal response to pyrogens
___ 2. Protects by denaturing tissue proteins
___ 3. Increases metabolic rate
___ 4. Reduces the availability of iron and zinc required
for bacterial proliferation
8. Match the description with the correct inflammatory response.
1.
Accounts for redness and heat in an inflamed area
A. Chemotaxis
2.
Inflammatory chemical released by injured cells
B. Diapedesis
3.
Promotes release of white blood cells from the bone
marrow
Cellular migration directed by a chemical gradient
C. Edema
4.
5.
D. Fibrin mesh
6.
Results from accumulation of fluid leaded from the
bloodstream
Phagocytic offspring of monocytes
E. Histamine
7.
Leukocytes pass through the wall of capillary
8.
First phagocytes to migrate into the injured area
F. Increased blood flow to an
area
G. Inflammatory chemicals
(including E)
H. Macrophages
9.
Walls off the area of injury
I. Neutrophils
9. Determine whether the following situations are examples or descriptions of passive immunity (P) or active
immunity (A).
1.
An individual receives Sabin polio vaccine
2.
Antibodies migrate through a pregnant woman’s placenta into the vascular system of fetus
3.
4.
A student nurse receives an injection of gamma globin after she has been exposed to viral
hepatitis
“Borrowed” immunity
5.
Immunologic memory is provided
6.
An individual suffers through chickenpox
10. There are several important differences between the primary and secondary immune response(s).
Identify if the following statements are primary (P) or secondary (S) immune responses.
1.
The initial response to an antigen; gearing-up stage
2.
3.
A lag period of several days occurs before antibodies specific to the antigen appear in the
bloodstream
Antibody levels increase rapidly and remain high for an extended period
4.
Immunologic memory is established
5.
The second, third, and subsequent responses to the same antigen
11. T cells and B cells exhibit certain similarities and differences. Place a check (√) the appropriate spaces in
the table below to indicate the lymphocyte type that exhibits each characteristics.
Characteristics
Originates in bone marrow from stem cells called hemocytoblasts
Progeny are plasma cells
Progeny include regulatory, helper, and cytotoxic cells
Progeny include memory cells
Is responsible for directly attacking foreign cells or virusinfected cells
Produces antibodies that are released to body fluids
Bears a cell-surface receptor capable of recognizing a specific
antigen
Forms clone upon stimulation
Accounts for most of the lymphocytes in the circulation
T Cell
B Cell
12. Match the following terms with the correct descriptions.
1.
A protein released by macrophages and activated T cells that
helps to protect other body cells from viral multiplication
A. Anaphylatic shock
2.
Any types of molecules that attract neutrophils and other
protective cells into a region where an immune response is
ongoing
B. Antibodies
3.
Proteins released by plasma cells that mark antigens for
destruction by phagocytes or complement
C. Chemotaxis factors
4.
A consequence of the release of histamine and of complement
activation
D. Complement
5.
C and G are examples of this class of molecules
E. Cytokines
6.
A group of plasma proteins that amplifies the immune response
by causing lysis of cellular pathogens once it has been “fixed” to
their surface
F. Inflammation
7.
Class of chemicals released by macrophages
G. Interferon
13. Several populations of T cells exist. Match the correct T cell with the descriptions below. Answer may
be used more than once.
1.
2.
3.
4.
5.
Binds with and releases chemicals that activate B
cells, T cells, and macrophages
Activated by recognizing both its antigen and selfprotein presented on the surface of a macrophage
Turns off the immune response when the “enemy” has
been routed
Directly attacks and lyses cellular pathogens
Initiates secondary response to a recognized antigen
A. Helper T cell
B. Cytotoxic cell
C. Regulatory cell
D. Memory T cell
14. The figure below is a flowchart of the immune system response that tests your understanding of the
interrelationships of that process. Several terms have been omitted from the schematic. Complete the
figure by inserting appropriate terms from the key choice below. NOTE: oval blanks indicate that they are
a cell type while the rectangular blanks represent the names of chemical molecules.
Cell Types: B cell, Helper T cell, Cytotoxic T Cell, Macrophage, Memory B cell, Memory T cell, Neutrophils,
Plasma cell
Molecules: Antibodies, Chemotactic factors, Complement, Cytokines, Interferon, Perforin