Molecular Identification and Physiological
... NH4þ, fructose, and phlorizin, indicating that transport is energy-dependent and that both glucose and fructose were taken up by the same carrier. Glucose import into vacuoles from two cold-induced tmt1 knockout lines or from triple knockout plants was substantially lower than into corresponding wil ...
... NH4þ, fructose, and phlorizin, indicating that transport is energy-dependent and that both glucose and fructose were taken up by the same carrier. Glucose import into vacuoles from two cold-induced tmt1 knockout lines or from triple knockout plants was substantially lower than into corresponding wil ...
Molecular Identification and Physiological Characterization of a
... NH4þ, fructose, and phlorizin, indicating that transport is energy-dependent and that both glucose and fructose were taken up by the same carrier. Glucose import into vacuoles from two cold-induced tmt1 knockout lines or from triple knockout plants was substantially lower than into corresponding wil ...
... NH4þ, fructose, and phlorizin, indicating that transport is energy-dependent and that both glucose and fructose were taken up by the same carrier. Glucose import into vacuoles from two cold-induced tmt1 knockout lines or from triple knockout plants was substantially lower than into corresponding wil ...
Signaling from synapse to nucleus: the logic behind the mechanisms Karl Deisseroth
... (Ca2þ/cAMP responsive element) regulatory sites controlling target genes, and becomes activated by phosphorylation on its Ser-133 residue (with modulatory influences exerted by other residues). A fast CaM-dependent kinase cascade and a slow MAP kinase cascade (likely to be cAMP-modulated) converge o ...
... (Ca2þ/cAMP responsive element) regulatory sites controlling target genes, and becomes activated by phosphorylation on its Ser-133 residue (with modulatory influences exerted by other residues). A fast CaM-dependent kinase cascade and a slow MAP kinase cascade (likely to be cAMP-modulated) converge o ...
Alternative splicing in human tumour viruses
... sequence silencers) or ISS (intronic sequence silencers) in a cooperative fashion to interfere with SR protein binding (Figure 2) ...
... sequence silencers) or ISS (intronic sequence silencers) in a cooperative fashion to interfere with SR protein binding (Figure 2) ...
METABOLIC AND ENDOCRINE ADAPTATIONS TO HEAT STRESS
... was thought to be the primary driver for the milk production loss. However, accumulating evidence indicates that HS influences animal metabolism and endocrine profiles independent of reduced feed intake. Previous studies comparing heat-stressed lactating cows with control group pair-fed (PF) to the ...
... was thought to be the primary driver for the milk production loss. However, accumulating evidence indicates that HS influences animal metabolism and endocrine profiles independent of reduced feed intake. Previous studies comparing heat-stressed lactating cows with control group pair-fed (PF) to the ...
Malonyl-CoA and AMP-activated protein kinase: An expanding
... enzyme in malonyl CoA formation (Fig. 2). Two principal isoform of ACC have been identified, a 265 KDa isoform commonly referred to as ACCα, which predominates in lipogenic tissues such as liver and adipose tissues, and a 280 KDa protein (ACCβ), which is the major isoform expressed in skeletal muscl ...
... enzyme in malonyl CoA formation (Fig. 2). Two principal isoform of ACC have been identified, a 265 KDa isoform commonly referred to as ACCα, which predominates in lipogenic tissues such as liver and adipose tissues, and a 280 KDa protein (ACCβ), which is the major isoform expressed in skeletal muscl ...
Engineering and Identifying Supercharged Proteins
... functional protein molecules directly into cells by translational fusion to supercharged proteins (Cronican et al., 2010). We initially demonstrated delivery of mCherry, ubiquitin, and Cre recombinase into multiple cell types using þ36 GFP (Cronican et al., 2010). These three proteins provide separa ...
... functional protein molecules directly into cells by translational fusion to supercharged proteins (Cronican et al., 2010). We initially demonstrated delivery of mCherry, ubiquitin, and Cre recombinase into multiple cell types using þ36 GFP (Cronican et al., 2010). These three proteins provide separa ...
Glycogen storage diseases - Journal of Clinical Pathology
... blood of the lactic acid which has been produced by muscles and other tissues with a high rate of glycolysis and converts it into glucose by the usual pathways of gluconeogenesis. In type I glycogen storage disease the liver itself produces large amounts of lactic acid from glycogen, because when gl ...
... blood of the lactic acid which has been produced by muscles and other tissues with a high rate of glycolysis and converts it into glucose by the usual pathways of gluconeogenesis. In type I glycogen storage disease the liver itself produces large amounts of lactic acid from glycogen, because when gl ...
Eukaryote-Like Serine/Threonine Kinases and Phosphatases in
... the scope of this review, phosphorylation in bacteria also occurs at Tyr residues, and it should be noted that most bacterial tyrosine kinases belong to the BY kinase family and do not resemble eukaryotic enzymes (reviewed in references 57 and 58). eSTKs in Bacteria In prokaryotes, protein phosphory ...
... the scope of this review, phosphorylation in bacteria also occurs at Tyr residues, and it should be noted that most bacterial tyrosine kinases belong to the BY kinase family and do not resemble eukaryotic enzymes (reviewed in references 57 and 58). eSTKs in Bacteria In prokaryotes, protein phosphory ...
Iduence of Dilution Rate on Enzyme Synthesis in
... Under citrate limitation biomass increased with increase in dilution rate up to a maximum of D = 0.042 h-l (Table I). At D = 0.051 h-l biomass tended to decrease sharply while residual citrate increased, indicating that 'wash-out ' was occurring. Under glucose limitation at dilution rates between D ...
... Under citrate limitation biomass increased with increase in dilution rate up to a maximum of D = 0.042 h-l (Table I). At D = 0.051 h-l biomass tended to decrease sharply while residual citrate increased, indicating that 'wash-out ' was occurring. Under glucose limitation at dilution rates between D ...
Seminars in
... Figure 1 Insulin metabolism. Several pathways are involved in the regulation of glucose, including insulin secretion by pancreatic B-cells, explaining the modality of effectiveness of medical treatments as diazoxide, somatostatin and a protein-restricted diet. Glucose and other fuels, such as amino ...
... Figure 1 Insulin metabolism. Several pathways are involved in the regulation of glucose, including insulin secretion by pancreatic B-cells, explaining the modality of effectiveness of medical treatments as diazoxide, somatostatin and a protein-restricted diet. Glucose and other fuels, such as amino ...
Iduence of Dilution Rate on Enzyme Synthesis in
... Under citrate limitation biomass increased with increase in dilution rate up to a maximum of D = 0.042 h-l (Table I). At D = 0.051 h-l biomass tended to decrease sharply while residual citrate increased, indicating that 'wash-out ' was occurring. Under glucose limitation at dilution rates between D ...
... Under citrate limitation biomass increased with increase in dilution rate up to a maximum of D = 0.042 h-l (Table I). At D = 0.051 h-l biomass tended to decrease sharply while residual citrate increased, indicating that 'wash-out ' was occurring. Under glucose limitation at dilution rates between D ...
Protein Analysis - GRiSP Research Solutions
... extract. Frequently, cultured cells can be ruptured using a detergent buffer without mechanical methods. The chemical structure of detergents enables them to disrupt membranes and solublize proteins. Detergents have both a polar and nonpolar portion, and can be classified by the characteristics of t ...
... extract. Frequently, cultured cells can be ruptured using a detergent buffer without mechanical methods. The chemical structure of detergents enables them to disrupt membranes and solublize proteins. Detergents have both a polar and nonpolar portion, and can be classified by the characteristics of t ...
148 - Blue Ridge Institute for Medical Research
... considerable effort has been expended to determine the assorted functions of protein kinase signal transduction pathways [1]. Moreover, dysregulation of protein kinases occurs in many diseases including cancer and inflammatory disorders. Protein kinases can modify the function of a protein in almost ...
... considerable effort has been expended to determine the assorted functions of protein kinase signal transduction pathways [1]. Moreover, dysregulation of protein kinases occurs in many diseases including cancer and inflammatory disorders. Protein kinases can modify the function of a protein in almost ...
Sugar signals and the control of plant growth and
... SnRK1 and miRNAs particularly encode ribosomal proteins, and also proteins involved in amino acid and sugar signalling (Confraria et al., 2013). In mammals, AMPK acts as a repressor of growth-promoting TOR signalling (Wullschleger et al., 2006) and has a role in cell cycle regulation by phosphorylat ...
... SnRK1 and miRNAs particularly encode ribosomal proteins, and also proteins involved in amino acid and sugar signalling (Confraria et al., 2013). In mammals, AMPK acts as a repressor of growth-promoting TOR signalling (Wullschleger et al., 2006) and has a role in cell cycle regulation by phosphorylat ...
Usha`s project - The University of Texas at Dallas
... PROTEIN STRUCTURE COMPARISON ALIGNMENT IN DALI DALI (Distance Matrix Alignment; Holm and Sander 1993a) uses distance matrices to represent each protein structure. In this method, each structure is represented as a two-dimensional array of distances between all the C-alpha atoms. Figure 19 illustrate ...
... PROTEIN STRUCTURE COMPARISON ALIGNMENT IN DALI DALI (Distance Matrix Alignment; Holm and Sander 1993a) uses distance matrices to represent each protein structure. In this method, each structure is represented as a two-dimensional array of distances between all the C-alpha atoms. Figure 19 illustrate ...
Autophagy regulation by nutrient signaling
... mTOR is a highly conserved serine/threonine kinase that is capable of integrating signals from many stimuli including amino acids, energy levels, oxygen, growth factors, and stress to coordinate cell growth and maintain metabolic homeostasis [59]. mTOR forms two functionally distinct complexes in ma ...
... mTOR is a highly conserved serine/threonine kinase that is capable of integrating signals from many stimuli including amino acids, energy levels, oxygen, growth factors, and stress to coordinate cell growth and maintain metabolic homeostasis [59]. mTOR forms two functionally distinct complexes in ma ...
putative mineral-specific proteins synthesized by a
... minerals goethite (FeOOH) and diaspore (AlOOH) were used in the BFM experiments. These minerals were selected because they are isostructural and have very similar surface properties (for example, surface charge and hydrophobicity), but only goethite can be used as a terminal electron acceptor for re ...
... minerals goethite (FeOOH) and diaspore (AlOOH) were used in the BFM experiments. These minerals were selected because they are isostructural and have very similar surface properties (for example, surface charge and hydrophobicity), but only goethite can be used as a terminal electron acceptor for re ...
Amino acid substitutions that specifically impair the transcriptional
... Brd4(L). As can be been seen in Figs. 2A and B, Brd4(L) was indeed detected in the eluates from the GST-E2 TAD column but not those from control columns. Similar experiments were then performed with the E2 TAD from HPV31. For this type also, the eluate from the column containing the GST-E2 TAD conta ...
... Brd4(L). As can be been seen in Figs. 2A and B, Brd4(L) was indeed detected in the eluates from the GST-E2 TAD column but not those from control columns. Similar experiments were then performed with the E2 TAD from HPV31. For this type also, the eluate from the column containing the GST-E2 TAD conta ...
12 Insights into the mechanisms underlying CFTR channel activity
... transmembrane segments in the membrane may be structured as lengthy helical segments extending from the membrane domain, perpendicular to the plane of the lipid bilayer. Shorter helical segments at the foot of these long extensions and lying parallel to the surface of the NBD heterodimer have been c ...
... transmembrane segments in the membrane may be structured as lengthy helical segments extending from the membrane domain, perpendicular to the plane of the lipid bilayer. Shorter helical segments at the foot of these long extensions and lying parallel to the surface of the NBD heterodimer have been c ...
a
... Mechanisms of ATP Synthesis: Substrate-Level Phosphorylation High-energy phosphate groups are transferred directly from phosphorylated substrates to ADP ...
... Mechanisms of ATP Synthesis: Substrate-Level Phosphorylation High-energy phosphate groups are transferred directly from phosphorylated substrates to ADP ...
ExamplePoster3 - Bridgewater College
... FACTORS INFLUENCING THE SYNTHESIS OF POLYHYDROXYBUTYRATE DEPOLYMERASE IN STREPTOMYCES SP. 5A Matthew B. Persinger, Matthew Shull, and Stephen F. Baron, Biology Dept., Bridgewater College, Bridgewater, VA 22812 ...
... FACTORS INFLUENCING THE SYNTHESIS OF POLYHYDROXYBUTYRATE DEPOLYMERASE IN STREPTOMYCES SP. 5A Matthew B. Persinger, Matthew Shull, and Stephen F. Baron, Biology Dept., Bridgewater College, Bridgewater, VA 22812 ...
Two glucose/xylose transporter genes from the yeast Candida
... of toxic compounds in hemicellulose hydrolysates, would also be used to convert the pentose fraction in these hydrolysates into ethanol. However, S. cerevisiae does not utilize xylose, which is the predominant pentose in hemicellulose, as a carbon and energy source. To circumvent this obstacle, the ...
... of toxic compounds in hemicellulose hydrolysates, would also be used to convert the pentose fraction in these hydrolysates into ethanol. However, S. cerevisiae does not utilize xylose, which is the predominant pentose in hemicellulose, as a carbon and energy source. To circumvent this obstacle, the ...
Analysis of p75NTR-dependent apoptotic
... apoptosis is associated with an increase in Rac and Jun kinase (JNK) activity, and recent work from our laboratory has shown that the p75NTR interactor, NRAGE, activates a mitochondrial death pathway involving JNK-dependent cytochrome C release and activation of Caspase-9, Caspase-7 and Caspase-3. D ...
... apoptosis is associated with an increase in Rac and Jun kinase (JNK) activity, and recent work from our laboratory has shown that the p75NTR interactor, NRAGE, activates a mitochondrial death pathway involving JNK-dependent cytochrome C release and activation of Caspase-9, Caspase-7 and Caspase-3. D ...
Phosphorylation
Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).