user manual for MS Amanda Standalone
... All considered modifications. Both fixed and variable modifications can be specified. Predefined modifications from the unimod file can be selected by specifying the modification name or title, a user defined modification can be used by specifying a user defined name and a delta mass. The syntax ...
... All considered modifications. Both fixed and variable modifications can be specified. Predefined modifications from the unimod file can be selected by specifying the modification name or title, a user defined modification can be used by specifying a user defined name and a delta mass. The syntax ...
Molecular Chaperones - Cellular Machines for Protein Folding
... The GroE proteins of the bacterium E. coli are the most extensively studied molecular chaperones.[21±24] The groEL and groES genes encode proteins of 57 kDa and 10 kDa size, respectively, which are both required for the viability of E. coli.[25] Thus, at least one essential E. coli protein cannot fo ...
... The GroE proteins of the bacterium E. coli are the most extensively studied molecular chaperones.[21±24] The groEL and groES genes encode proteins of 57 kDa and 10 kDa size, respectively, which are both required for the viability of E. coli.[25] Thus, at least one essential E. coli protein cannot fo ...
Metabolic Pathways
... Catabolic Pathways • Catabolic pathways break down complex molecules into simpler ones. • This results in the release of energy. • Respiration is an example of a catabolic pathway as glucose is broken down to produce carbon dioxide, water and ATP. ...
... Catabolic Pathways • Catabolic pathways break down complex molecules into simpler ones. • This results in the release of energy. • Respiration is an example of a catabolic pathway as glucose is broken down to produce carbon dioxide, water and ATP. ...
ppt
... 2. One C is broken off (CO2) and NAD accepts energy (NADH) 3. The second C is broken off (CO2) and NAD accepts the energy…at this point the acetyl group has ...
... 2. One C is broken off (CO2) and NAD accepts energy (NADH) 3. The second C is broken off (CO2) and NAD accepts the energy…at this point the acetyl group has ...
Part 2
... 2. One C is broken off (CO2) and NAD accepts energy (NADH) 3. The second C is broken off (CO2) and NAD accepts the energy…at this point the acetyl group has ...
... 2. One C is broken off (CO2) and NAD accepts energy (NADH) 3. The second C is broken off (CO2) and NAD accepts the energy…at this point the acetyl group has ...
The Effect of Irradiatied Adsorbed Species on cellulose by ESR
... distinctive features and when benzophenone was added, elements of each ones spectra can be seen in the spectra of the mixture. This mixture also showed unique elements of its own that were not present in either the benzophenone or cellulose ESR. This supports the idea that perhaps the benzophenone i ...
... distinctive features and when benzophenone was added, elements of each ones spectra can be seen in the spectra of the mixture. This mixture also showed unique elements of its own that were not present in either the benzophenone or cellulose ESR. This supports the idea that perhaps the benzophenone i ...
Regulated trafficking of neurotransmitter transporters: common notes
... cellular redistribution of the various transporters. Probably the most commonly employed technique involves the covalent modification of cell surface proteins with a membrane impermeant biotinylation reagent. After biotiny1 lation, cells are lysed and the biotinylated/cell surface proteins are batch ...
... cellular redistribution of the various transporters. Probably the most commonly employed technique involves the covalent modification of cell surface proteins with a membrane impermeant biotinylation reagent. After biotiny1 lation, cells are lysed and the biotinylated/cell surface proteins are batch ...
The role of mTOR signaling in the regulation of protein synthesis
... we found that the mass of the five major muscles involved in ankle joint movement were significantly reduced after 7 days of immobilization (Fig. 1B) (note: the animal body weight decreases slightly during the first 2 days of immobilization, supplementary material Fig. S1). Furthermore, with the sur ...
... we found that the mass of the five major muscles involved in ankle joint movement were significantly reduced after 7 days of immobilization (Fig. 1B) (note: the animal body weight decreases slightly during the first 2 days of immobilization, supplementary material Fig. S1). Furthermore, with the sur ...
Distribution bias analysis of germline and somatic single
... patient survival. Patient clinical information was retrieved for TCGA samples from their FTP site (https:// tcga-data.nci.nih.gov/tcgafiles/ftp_auth/distro_ftpusers/anonymous/tumor/). For each key pfsSNV in a specific cancer type that we identified through the prioritization process, based on the pr ...
... patient survival. Patient clinical information was retrieved for TCGA samples from their FTP site (https:// tcga-data.nci.nih.gov/tcgafiles/ftp_auth/distro_ftpusers/anonymous/tumor/). For each key pfsSNV in a specific cancer type that we identified through the prioritization process, based on the pr ...
Centromere dynamics
... basis for epigenetic specification of centromere. A study from the pathogenic yeast reveals that pre-existing centromeres remain functional, but if they are isolated as naked DNA and reintroduced back into the cell, functional centromeres do not form [15]. These and other studies might force us to ...
... basis for epigenetic specification of centromere. A study from the pathogenic yeast reveals that pre-existing centromeres remain functional, but if they are isolated as naked DNA and reintroduced back into the cell, functional centromeres do not form [15]. These and other studies might force us to ...
Protein S-nitrosylation in photosynthetic organisms: A
... important because they give rise to more reactive molecules, particularly nitrogen oxides (e.g. NO2, N2O3) and peroxynitrite (ONOO−), collectively named reactive nitrogen species (RNS). These molecules have much higher reactivity than NO and may play a dual role in biological systems, both as signal ...
... important because they give rise to more reactive molecules, particularly nitrogen oxides (e.g. NO2, N2O3) and peroxynitrite (ONOO−), collectively named reactive nitrogen species (RNS). These molecules have much higher reactivity than NO and may play a dual role in biological systems, both as signal ...
Ammonium Dodecyl Sulfate as an Alternative to Sodium Dodecyl
... techniques obviously add an undesirable step for MALDI analysis. The sample-cleaning step can result in protein loss, especially for hydrophobic or membrane proteins.16,17 An alternative approach is to develop new surfactants that have properties similar to those of SDS but will be MS-compatible. Fo ...
... techniques obviously add an undesirable step for MALDI analysis. The sample-cleaning step can result in protein loss, especially for hydrophobic or membrane proteins.16,17 An alternative approach is to develop new surfactants that have properties similar to those of SDS but will be MS-compatible. Fo ...
mammalian hibernation: biochemical adaptation
... by UCP1. They are protonated in the acidic intermembrane space, and then neutral FFA-H diffuse across the inner membrane and dissociate again in the more basic pH environment of the matrix. The net effect is that UCP1 functions as a protonophore to return Hþ to the matrix. Although both models can a ...
... by UCP1. They are protonated in the acidic intermembrane space, and then neutral FFA-H diffuse across the inner membrane and dissociate again in the more basic pH environment of the matrix. The net effect is that UCP1 functions as a protonophore to return Hþ to the matrix. Although both models can a ...
CHAPTER 13 – PROKARYOTE GENES: E. COLI LAC OPERON
... the same genomic sequence. How then do cells develop and function differently from each other? The answer lies in the regulation of gene expression. Only a subset of all the genes is expressed (i.e. are functionally active) in any given cell participating in a ...
... the same genomic sequence. How then do cells develop and function differently from each other? The answer lies in the regulation of gene expression. Only a subset of all the genes is expressed (i.e. are functionally active) in any given cell participating in a ...
October 24 AP Biology - John D. O`Bryant School of Math & Science
... What else is produced that is not listed in this equation? Why do we breathe? AP Biology ...
... What else is produced that is not listed in this equation? Why do we breathe? AP Biology ...
Plant serine/arginine-rich proteins and their role in pre
... pattern of SR1 is regulated in an organ- and tissue-specific manner and by temperature. Results from transient gene expression assays indicate that alternative splicing of SR1 is not an autoregulatory mechanism used to control the transcript level of the full-length protein [50]. Overexpression of S ...
... pattern of SR1 is regulated in an organ- and tissue-specific manner and by temperature. Results from transient gene expression assays indicate that alternative splicing of SR1 is not an autoregulatory mechanism used to control the transcript level of the full-length protein [50]. Overexpression of S ...
Chromatin Regulators and Transcriptional Control of Drosophila
... as transcription co-factors. The interplay between transcriptional activators and repressors is modulated by co-factors at cis-regulatory DNA modules (CRMs) to generate precise gene expression patterns. In this study, we have investigated the in vivo function of four co-factors, dAda2b, Reptin, Ebi ...
... as transcription co-factors. The interplay between transcriptional activators and repressors is modulated by co-factors at cis-regulatory DNA modules (CRMs) to generate precise gene expression patterns. In this study, we have investigated the in vivo function of four co-factors, dAda2b, Reptin, Ebi ...
Uncoupling effect of polyunsaturated fatty acid deficiency in isolated
... in this group persisted after the addition of oligomycin (30 %), whereas it was abolished with potassium cyanide. Hence it seems that the increase in cell respiration is due to a mitochondrial process that is not entirely linked to ATP synthesis. Such an effect could be due to mitochondrial uncoupli ...
... in this group persisted after the addition of oligomycin (30 %), whereas it was abolished with potassium cyanide. Hence it seems that the increase in cell respiration is due to a mitochondrial process that is not entirely linked to ATP synthesis. Such an effect could be due to mitochondrial uncoupli ...
Camp 1 - University of California, Santa Cruz
... important pathway for the regeneration of NAD+ is reduction of pyruvate to lactate. Pyruvate, the oxidizing agent, is reduced to lactate. lactate O dehydrogenase ...
... important pathway for the regeneration of NAD+ is reduction of pyruvate to lactate. Pyruvate, the oxidizing agent, is reduced to lactate. lactate O dehydrogenase ...
Protein S-nitrosylation in photosynthetic organisms: A
... important because they give rise to more reactive molecules, particularly nitrogen oxides (e.g. NO2, N2O3) and peroxynitrite (ONOO−), collectively named reactive nitrogen species (RNS). These molecules have much higher reactivity than NO and may play a dual role in biological systems, both as signal ...
... important because they give rise to more reactive molecules, particularly nitrogen oxides (e.g. NO2, N2O3) and peroxynitrite (ONOO−), collectively named reactive nitrogen species (RNS). These molecules have much higher reactivity than NO and may play a dual role in biological systems, both as signal ...
Ubiquitin ligases and beyond EDITORIAL Open Access Ivan Dikic
... reading today, Cecile Pickart traced the evolution of research on ubiquitination from its origins in the proteasomal degradation of proteins through the revelation that it has a central role in cell cycle regulation and the recognition of regulatory roles for ubiquitin in intracellular membrane tran ...
... reading today, Cecile Pickart traced the evolution of research on ubiquitination from its origins in the proteasomal degradation of proteins through the revelation that it has a central role in cell cycle regulation and the recognition of regulatory roles for ubiquitin in intracellular membrane tran ...
Fast evolutionary rates associated with functional loss in class I
... GLUT4 have been well studied and are transcriptionally upregulated under glucose deprivation conditions [10]. In terms of primary amino acid sequence, SGTP1 and SGTP4 were reported to be homologous to human GLUT1 [11], while SGTP2 is more similar to GLUT4 [4]. Glucose transporters undergo conformati ...
... GLUT4 have been well studied and are transcriptionally upregulated under glucose deprivation conditions [10]. In terms of primary amino acid sequence, SGTP1 and SGTP4 were reported to be homologous to human GLUT1 [11], while SGTP2 is more similar to GLUT4 [4]. Glucose transporters undergo conformati ...
G PROTEIN βγ SUBUNITS
... amino acids, and the remainder of the molecule, which is made up of a sequence motif that is repeated seven times. This repeating sequence, called a WD repeat, is not unique to the Gβ subunit but occurs in approximately 40 other proteins that make up the WD-repeat superfamily. Members of this family ...
... amino acids, and the remainder of the molecule, which is made up of a sequence motif that is repeated seven times. This repeating sequence, called a WD repeat, is not unique to the Gβ subunit but occurs in approximately 40 other proteins that make up the WD-repeat superfamily. Members of this family ...
Phosphorylation
Phosphorylation is the addition of a phosphate (PO43−) group to a protein or other organic molecule. Phosphorylation and its counterpart, dephosphorylation, turn many protein enzymes on and off, thereby altering their function and activity. Protein phosphorylation is one type of post-translational modification.Protein phosphorylation in particular plays a significant role in a wide range of cellular processes. Its prominent role in biochemistry is the subject of a very large body of research (as of March 2015, the Medline database returns over 240,000 articles on the subject, largely on protein phosphorylation).