Quinto trabajo
... To examine striatal and cortical protein levels of Bax, Bak, Bcl-2, Bcl-xL, Bim and Bad Western blot was performed as described elsewhere (Perez-Navarro et al., 2005). Antibodies used were: Bcl-2 (mouse monoclonal, 1:2000), Bcl-xL (mouse monoclonal, 1:500), Bak (rabbit polyclonal, 1:2000), Bim (rabb ...
... To examine striatal and cortical protein levels of Bax, Bak, Bcl-2, Bcl-xL, Bim and Bad Western blot was performed as described elsewhere (Perez-Navarro et al., 2005). Antibodies used were: Bcl-2 (mouse monoclonal, 1:2000), Bcl-xL (mouse monoclonal, 1:500), Bak (rabbit polyclonal, 1:2000), Bim (rabb ...
PDF version - Richard Andersen
... in both LIP and 7a). Thus the duration of the S activity is usually isolated in this study. 3. The typical activity of IPL neurons during the delayed-sac- considerably longer than the duration of the saccade itself. 11. In area LIP the onset latencies of the LS activity ranged cade task has three ba ...
... in both LIP and 7a). Thus the duration of the S activity is usually isolated in this study. 3. The typical activity of IPL neurons during the delayed-sac- considerably longer than the duration of the saccade itself. 11. In area LIP the onset latencies of the LS activity ranged cade task has three ba ...
Author`s personal copy - Laboratoire de Neurosciences Cognitives
... segment of the globus pallidus (GPi). The anatomo-physiological organization of the BG and their output suggested that interfering with such hyper-activity could restore motor function and improve parkinsonism. Several animal models in rodents and primates, as well as clinical studies and neurosurgi ...
... segment of the globus pallidus (GPi). The anatomo-physiological organization of the BG and their output suggested that interfering with such hyper-activity could restore motor function and improve parkinsonism. Several animal models in rodents and primates, as well as clinical studies and neurosurgi ...
Neurofilament and Calcium-Binding Proteins in the
... association areas located in the parietal and temporal cortex (Kondo et al., 1994). Previous analyses of the distribution of calcium-binding proteins in the macaque monkey cingulate cortex have shown that parvalbuminimmunoreactive interneurons are codistributed with neurofilament protein-immunoreact ...
... association areas located in the parietal and temporal cortex (Kondo et al., 1994). Previous analyses of the distribution of calcium-binding proteins in the macaque monkey cingulate cortex have shown that parvalbuminimmunoreactive interneurons are codistributed with neurofilament protein-immunoreact ...
computational and in vitro studies of persistent activity
... longer present in the environment is thought to be the neural correlate of working memory and it is known as persistent activity. It has been observed in many cortical areas of awake monkeys performing working memory tasks (Fuster, 1995; Goldman-Rakic, 1995). Apart from its implication in working me ...
... longer present in the environment is thought to be the neural correlate of working memory and it is known as persistent activity. It has been observed in many cortical areas of awake monkeys performing working memory tasks (Fuster, 1995; Goldman-Rakic, 1995). Apart from its implication in working me ...
Different Stimuli, Different Spatial Codes: A Visual Map and an
... overlap saccade task (Figure 2; see also Materials and Methods) allowing sensory-related activity (02500 ms after the target) to be dissociated from saccade-related activity (20 ms before saccade onset to 20 ms before saccade offset). We selected neurons that responded significantly for at least one ...
... overlap saccade task (Figure 2; see also Materials and Methods) allowing sensory-related activity (02500 ms after the target) to be dissociated from saccade-related activity (20 ms before saccade onset to 20 ms before saccade offset). We selected neurons that responded significantly for at least one ...
Impaired Cl Extrusion in Layer V Pyramidal Neurons of Chronically
... D. A. Prince, unpublished data) and decreased KCC2 expression resulting in a positive shift in ECl and depolarizing GABAA responses has been reported after axotomy, other neuronal injuries, and seizures (Malek et al. 2003; Nabekura et al. 2002; Woo et al. 2002). It is possible that sufficient KCC2 a ...
... D. A. Prince, unpublished data) and decreased KCC2 expression resulting in a positive shift in ECl and depolarizing GABAA responses has been reported after axotomy, other neuronal injuries, and seizures (Malek et al. 2003; Nabekura et al. 2002; Woo et al. 2002). It is possible that sufficient KCC2 a ...
During Arm-Reaching and Isometric-Force Tasks
... geometry and no displacement of the hand. Preliminary results of this study have been reported previously (Hamel-Pâquet et al. 2002, 2003). Terms borrowed from mechanics (e.g., kinematics, kinetics, dynamics) are used throughout this paper. However, they are used here only in a general sense as con ...
... geometry and no displacement of the hand. Preliminary results of this study have been reported previously (Hamel-Pâquet et al. 2002, 2003). Terms borrowed from mechanics (e.g., kinematics, kinetics, dynamics) are used throughout this paper. However, they are used here only in a general sense as con ...
Transfer Effects and Conditional Learning in Rats With Selective
... All rats were initially habituated 1 day for 30 min in their training box. During this period, food pellets were placed in the magazine and on the shelf below the viewing windows in the mask covering the touchscreen. The rats were then given 2 days (50 trials per day) of pretraining designed so that ...
... All rats were initially habituated 1 day for 30 min in their training box. During this period, food pellets were placed in the magazine and on the shelf below the viewing windows in the mask covering the touchscreen. The rats were then given 2 days (50 trials per day) of pretraining designed so that ...
The industrial melanism mutation in British peppered moths is a
... wording of the record implies that it was rare but not completely unknown at this time. Establishing how long before this date the carbonaria mutation occurred is complicated because it could have existed undetected at a low frequency for hundreds of years (Supplementary Methods). Our approach to th ...
... wording of the record implies that it was rare but not completely unknown at this time. Establishing how long before this date the carbonaria mutation occurred is complicated because it could have existed undetected at a low frequency for hundreds of years (Supplementary Methods). Our approach to th ...
MOTION DETECTION MECHANISMS
... stimulate the nearest ommatidium to the left, the beetle turned towards the left. When a dark (-1) bar was followed by a dark bar on the left, the beetle also turned to the left. But, when a bright (+1) bar followed a dark (-1) bar on the left, the beetle turned to the right. From these key observat ...
... stimulate the nearest ommatidium to the left, the beetle turned towards the left. When a dark (-1) bar was followed by a dark bar on the left, the beetle also turned to the left. But, when a bright (+1) bar followed a dark (-1) bar on the left, the beetle turned to the right. From these key observat ...
Paper
... monkey (Cebus apella). The resulting pattern of labeled cells was assessed in relation to the three-dimensional geometry of the claustrum, as well as recent reports of claustrum-prefrontal connections in other primates. Claustrum-prefrontal projections were extensive, and largely concentrated in the ...
... monkey (Cebus apella). The resulting pattern of labeled cells was assessed in relation to the three-dimensional geometry of the claustrum, as well as recent reports of claustrum-prefrontal connections in other primates. Claustrum-prefrontal projections were extensive, and largely concentrated in the ...
Higginbotham H, Eom TY, Mariani LE, Bachleda A, Hirt J, Gukassyan V, Cusack CL, Lai C, Caspary T, Anton ES. Developmental Cell. 2012, Nov 13 23(5):925-38. Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex.
... of cilia function for cortical development and function is evident in various developmental brain disorders, such as Joubert, Meckel-Gruber, Orofaciodigital, and Bardet-Biedl syndromes (commonly referred to as ciliopathies), where disrupted cilia function and the resultant changes in cortical format ...
... of cilia function for cortical development and function is evident in various developmental brain disorders, such as Joubert, Meckel-Gruber, Orofaciodigital, and Bardet-Biedl syndromes (commonly referred to as ciliopathies), where disrupted cilia function and the resultant changes in cortical format ...
Disruption of experience-dependent synaptic modifications in striate
... homotypic points in the 2 retinae impinge upon their cortical targets at the same time. The summation of this convergent input depolarizes the target neuron above some threshold and, according to Hebb’s rule, these connections are strengthened. When the signals from the 2 eyes become asynchronous, s ...
... homotypic points in the 2 retinae impinge upon their cortical targets at the same time. The summation of this convergent input depolarizes the target neuron above some threshold and, according to Hebb’s rule, these connections are strengthened. When the signals from the 2 eyes become asynchronous, s ...
Eye-specific Segregation Requires Neural Activity in Three
... action potentials in the optic nerves of three-eyed tadpoles are necessary for the formation and maintenance of eye-specific segregation in dually innervated tecta. They are also consistent with the hypothesis that the competitive fiber interactions that “fine tune” the normal pattern of retinotecta ...
... action potentials in the optic nerves of three-eyed tadpoles are necessary for the formation and maintenance of eye-specific segregation in dually innervated tecta. They are also consistent with the hypothesis that the competitive fiber interactions that “fine tune” the normal pattern of retinotecta ...
J. Neurophysiol. - Nonlinear Dynamics Group
... the firing activity of specific populations of neurons to animal behaviors, defining sites with neuronal activity in particular behavioral contexts as the functional areas corresponding to those behaviors. Although such observations are interesting in themselves, these studies do not necessarily exa ...
... the firing activity of specific populations of neurons to animal behaviors, defining sites with neuronal activity in particular behavioral contexts as the functional areas corresponding to those behaviors. Although such observations are interesting in themselves, these studies do not necessarily exa ...
The birth, death and resurrection of avoidance: a
... thought to indicate conditioned fear do not co-vary with the acquisition or performance of the avoidance response.6,60 Such observations created a paradox for two-factor fear theory. Authors such as Bolles43,60 and Seligman62 viewed these observations as particularly damaging to the avoidance paradi ...
... thought to indicate conditioned fear do not co-vary with the acquisition or performance of the avoidance response.6,60 Such observations created a paradox for two-factor fear theory. Authors such as Bolles43,60 and Seligman62 viewed these observations as particularly damaging to the avoidance paradi ...
The birth, death and resurrection of avoidance
... thought to indicate conditioned fear do not co-vary with the acquisition or performance of the avoidance response.6,60 Such observations created a paradox for two-factor fear theory. Authors such as Bolles43,60 and Seligman62 viewed these observations as particularly damaging to the avoidance paradi ...
... thought to indicate conditioned fear do not co-vary with the acquisition or performance of the avoidance response.6,60 Such observations created a paradox for two-factor fear theory. Authors such as Bolles43,60 and Seligman62 viewed these observations as particularly damaging to the avoidance paradi ...
Structure of Receptive Fields in Area 3b of Primary Somatosensory
... hemispheres using standard techniques (Phillips et al., 1988; Mountcastle et al., 1991). On each recording day, a multielectrode microdrive (Mountcastle et al., 1991) was loaded with seven quartz-coated platinum /tungsten (90/10) electrodes (diameter, 80 mm; tip diameter, 4 mm; and impedance, 1–5 MV ...
... hemispheres using standard techniques (Phillips et al., 1988; Mountcastle et al., 1991). On each recording day, a multielectrode microdrive (Mountcastle et al., 1991) was loaded with seven quartz-coated platinum /tungsten (90/10) electrodes (diameter, 80 mm; tip diameter, 4 mm; and impedance, 1–5 MV ...
Functional Heterogeneity in the Bed Nucleus of the Stria Terminalis
... number and location (e.g., compare Moga et al., 1989 and Ju and Swanson, 1989). Posteriorly located BNST nuclei are involved in ...
... number and location (e.g., compare Moga et al., 1989 and Ju and Swanson, 1989). Posteriorly located BNST nuclei are involved in ...
Effect of Tactile Inputs on Thalamic Responses to Noxious
... al. 1993; Rigamonti et al. 1978). A large number of neurons in the dorsal column nuclei (DCN) respond to both visceral and tactile stimulation (for review, see Al-Chaer et al. 1996a; Berkley and Hubscher 1995; Willis et al. 1999). Recent studies (e.g., Al-Chaer et al. 1996a– c, 1997a,b, 1998) have d ...
... al. 1993; Rigamonti et al. 1978). A large number of neurons in the dorsal column nuclei (DCN) respond to both visceral and tactile stimulation (for review, see Al-Chaer et al. 1996a; Berkley and Hubscher 1995; Willis et al. 1999). Recent studies (e.g., Al-Chaer et al. 1996a– c, 1997a,b, 1998) have d ...
Dynamics of spontaneous activity in the cerebral cortex across brain states
... d’aquesta tesi per mitjà del servei TDX (www.tdx.cat) i a través del Dipòsit Digital de la UB (diposit.ub.edu) ha estat autoritzada pels titulars dels drets de propietat intel·lectual únicament per a usos privats emmarcats en activitats d’investigació i docència. No s’autoritza la seva reproducció a ...
... d’aquesta tesi per mitjà del servei TDX (www.tdx.cat) i a través del Dipòsit Digital de la UB (diposit.ub.edu) ha estat autoritzada pels titulars dels drets de propietat intel·lectual únicament per a usos privats emmarcats en activitats d’investigació i docència. No s’autoritza la seva reproducció a ...
Repetition suppression - Philosophical Transactions of the Royal
... neuroscience. Over the last few decades, large-scale electrophysiological recordings in animal models have allowed for descriptions of neural activity at high spatio-temporal resolution. This has provided important insight into some of the underlying principles and mechanisms of neural coding, allow ...
... neuroscience. Over the last few decades, large-scale electrophysiological recordings in animal models have allowed for descriptions of neural activity at high spatio-temporal resolution. This has provided important insight into some of the underlying principles and mechanisms of neural coding, allow ...