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BN16 Neural plasticity
BN16 Neural plasticity

...   in activity of specific Purkinje cells  Climbing fibers may carry error signals  corrections  parallel fiber influence  input specificity  only affects active synapses of a parallel fiber ~ ...
State Dependant Synaptic Plasticity in Purkinje Cells
State Dependant Synaptic Plasticity in Purkinje Cells

... Department of Neurobiology, Life Science Institute, Hebrew University of Jerusalem, Israel One of the popular theories of cerebellar function assumes that the cerebellum stores memory traces at the parallel fibers (pf) synapse. According to this theory, the climbing fibers (cf) control the learning ...
Getting on your Nerves
Getting on your Nerves

... Getting on your Nerves ...
Dorsal View Ventral View Dorsal View
Dorsal View Ventral View Dorsal View

... Cerebellar Input and Output pathways INPUT-1: Mossy fibers, ascend through the cerebellar white matter and form excitatory synapses on granule cells Granule cells’ axons form parallel fibers, each of these fibers form excitatory synapses with numerous Purkinje Cells.  All output from the cerebellar ...
Cerebellum
Cerebellum

... Dysarthria and scanning speech Nystagmus Hypotonia Cerebellar ataxia (Romberg test) Dysmetria Diplopia Cognitive dysfunction ...
A real-time model of the cerebellar circuitry underlying classical
A real-time model of the cerebellar circuitry underlying classical

... turn, form excitatory synapses onto the Purkinje cells (Pu) and the basket and stellate interneurons (I) in the cerebellar cortex. The IO gives rise to the US conveying CF which also converge onto the Purkinje cells. Due to this convergence of PF and CF onto the Purkinje cells, these neurons are see ...
Second lecture test
Second lecture test

... D. muscle weakness 4. The pontocerebellum is concerned with A. regulation of muscle tone of limbs B. maintenance of equilibrium C. regulation of muscle tone of trunk D. smooth performance of skilled acts 5. Most of the efferent fibers of the cerebellum are projected to the A. midbrain (superior pedu ...
Cerebellum - UCSD Cognitive Science
Cerebellum - UCSD Cognitive Science

... •  15 million in human cerebellum ...
Cerebellar system and diseases
Cerebellar system and diseases

... Motor coordination  Cerebellum does not initiate movement  It contributes to coordination, precision, and accurate timing.  It receives input from sensory systems and from other parts of the brain and spinal cord,  It integrates these inputs to tune fine motor activity. Because of this fine-tun ...
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Eyeblink conditioning

Eyeblink conditioning (EBC) is a form of classical conditioning that has been used extensively to study neural structures and mechanisms that underlie learning and memory. The procedure is relatively simple and usually consists of pairing an auditory or visual stimulus (the conditioned stimulus (CS)) with an eyeblink-eliciting unconditioned stimulus (US) (e.g. a mild puff of air to the cornea or a mild shock). Naïve organisms initially produce a reflexive, unconditioned response (UR) (e.g. blink or extension of nictitating membrane) that follows US onset. After many CS-US pairings, an association is formed such that a learned blink, or conditioned response (CR), occurs and precedes US onset. The magnitude of learning is generally gauged by the percentage of all paired CS-US trials that result in a CR. Under optimal conditions, well-trained animals produce a high percentage of CRs (> 90%). The conditions necessary for, and the physiological mechanisms that govern, eyeblink CR learning have been studied across many mammalian species, including mice, rats, guinea pigs, rabbits, ferrets, cats, and humans. Historically, rabbits have been the most popular research subjects.
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