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PBL- Case 1: Cardiac Arrhythmias Pre
PBL- Case 1: Cardiac Arrhythmias Pre

... High prevalence of CAD, CHF and valvular disease and calcification (common in older patients) puts them at higher risk of atrial fibrillation. Cardiac valvular stenosis or regurgitation caused by either rheumatic or age related degenerative changes increases left atrial pressure and results in the e ...
Heart Physiology
Heart Physiology

... 4. The atria contract forcing the blood into the ventricles vi. Ventricular Systole 1. The atria relax and the ventricles begin to contract 2. The AV valves close 3. Pressure increases until the pressure is greater then the arteries 4. The semilunar valves are forced open 5. Blood is forced into eit ...
Primary FRCA MCQ/SBA Revision Day 23rd
Primary FRCA MCQ/SBA Revision Day 23rd

... b) is elevated in tricuspid stenosis c) is elevated in atrial fibrillation d) is elevated in tricuspid regurgitation e) when enlarged are known as cannon a waves 17) In Cardiac ventricular muscle a) cells exhibit automaticity b) the cell membranes are largely impermeable to negatively charged ions c ...
Uncomplicated Acute Myocardial Infarction Results in Protracted
Uncomplicated Acute Myocardial Infarction Results in Protracted

... Left ventricular (LV) mass is an important cardiovascular risk factor. The beta-I adrenoceptor (BIAR) is a key cell surface signalling protein expressed in the heart and it’s variation may, therefore, affect LV mass. The gene of the BlAR has two known functional polymorphisms; one of these changes t ...
Anesthesia for Patients with Valvular Heart Disease for Non
Anesthesia for Patients with Valvular Heart Disease for Non

... Mitral stenosis is a narrowing of the mitral valve orifice that results in left atrial hypertension, limited filling of the LV, pulmonary congestion, and in moderate to severe cases, pulmonary arterial hypertension and right ventricular pressure overload. Dyspnea is the most common presenting sympto ...
1-History Taking
1-History Taking

... text book symptoms  Angina doesn’t always mean coronary artery disease.  A high index of suspicion is necessary to avoid missing the diagnosis of acute aortic dissection.  Not all patients with acute MI develop ECG changes. ...
The Cardiac Cycle
The Cardiac Cycle

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Evaluation of Syncope in Children

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Right Heart Failure in Cardiac Surgical Patients
Right Heart Failure in Cardiac Surgical Patients

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Double right ventricle outflow tract repair icd 10

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Arrhythmogenic Right Ventricular Cardiomypathy (ARVC)
Arrhythmogenic Right Ventricular Cardiomypathy (ARVC)

... Major advances have been made in genetic testing for ARVC in recent years. Genetic testing is now commercially available and involves screening five genes that can cause the condition. The gene alteration will be identified in approximately 40-50% of families. Further research is needed to identify ...
The Transport System Study Guide
The Transport System Study Guide

... Address the Learning Objectives below H.5.1 Explain the events of the cardiac cycle, including atrial and ventricular systole and diastole, and heart sounds. H.5.2 Analyse data showing pressure and volume changes in the left atrium, left ventricle and the aorta, during the cardiac cycle. H.5.3 Outli ...
Cardio Investigations - Ipswich-Year2-Med-PBL-Gp-2
Cardio Investigations - Ipswich-Year2-Med-PBL-Gp-2

... relates to coronary flow. Images are acquired with a gamma camera. This test can distinguish between reversible and irreversible ischaemia (the latter signifying infarcted tissue) ...
myocard*al and per*card*al d*seases
myocard*al and per*card*al d*seases

... obstruction occurs in 25% of patients, and may in part be secondary to the abnormal position of the mitral valve as well as the obstructing subaortic hypertrophic cardiac muscle.  The cardiac myofibrils and myofilaments demonstrate disarray and myocardial fibrosis.  Systolic pump function is prese ...
Rapid ventricular pacing versus adenosine administration for
Rapid ventricular pacing versus adenosine administration for

... Open heart surgery for patients who needs valvular replacement is standard approach. Many patients with a single diseased valve were declined for surgery because of advanced age, end-stage disease and comorbidities with short life expectancy. In such patients percutaneous transfemoral aortic valve ...
The Cardiovascular System: Part 1
The Cardiovascular System: Part 1

... 1) Describe the structures of the heart that are responsible for regulating the movement of blood from one chamber to the next. 2) The pathway by which action potentials from the sinoatrial node travel through the heart is important for the normal function of the heart. Describe the conduction pathw ...
Hypertrophic Cardiomyopathy - Pathophysiology
Hypertrophic Cardiomyopathy - Pathophysiology

... leaflet or the chordal structures inserting on this leaflet being pulled into the LVOT during systole by the enlarged papillary muscles. Here it is caught in the blood flow and pushed toward and often ultimately against the interventricular septum. The initial pulling of the mitral valve leaflet tow ...
Premature Ventricular Contractions
Premature Ventricular Contractions

... Catecholaminergic PVT ...
Long non-coding RNA (lncRNA) LIPCAR predicts survival in heart
Long non-coding RNA (lncRNA) LIPCAR predicts survival in heart

... had an episode of myocardial infarction. Further, LIPCAR levels are associated with future cardiovascular deaths in heart failure patients independent of other predictors. For this reasons, LIPCAR enables the timely diagnosis of the disease course and renders possible a therapy of the patient at an ...
SESSION 10 - Middle Mediastinum, Pericardium, Heart And Great
SESSION 10 - Middle Mediastinum, Pericardium, Heart And Great

... 26. What is the name of the band of tissue arising from the right branch of the Bundle of His that supplies the anterior papillary muscle in the right ventricle? ...
Phonocardiography, External Pulse Recordings, and
Phonocardiography, External Pulse Recordings, and

... • Reflects volume change in the internal jugular vein and closely resembles the pressure changes in the right atrium • A wave atrial contraction • C wave onset of ventricular contraction • X descent atrial diastole • V wave atrial filling before AV valves open • Y descent AV valves open filling of t ...
Non-Invasive Cardiovascular Examination
Non-Invasive Cardiovascular Examination

... sounds may be heard from ventricular filling and the abnormal flow of blood through the heart resulting in turbulence, producing murmurs.  S1 is due to mitral and tricuspid valve closure and may normally be split. Wider splitting is heard in right bundle branch block (RBBB). Increased intensity of ...
EKG
EKG

... An electrocardiogram (EKG or ECG) is a graphic representation of the heart’s electrical activity. ...
Cardiovascular System: The Heart
Cardiovascular System: The Heart

... AV valves closed to prevent _____________ As ventricular pressure builds up, ___________________ valves are forced open, blood into __________________________________ trunk 3. Early diastole _____________begin to relax (throughout ventricular systole, atria were in diastole- filling with blood as pr ...
Treatment - Digoxin Immune Fab
Treatment - Digoxin Immune Fab

... Classic triad is angine, syncope and heart failure. Signs include slow rising pulse, aortic thrill, ejection systolic murmur which radiates to carotids. In severa AS second heart sound be inaudible. ECG and echo are used to diagnose AS. Treatment is valve replacement. ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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