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Understanding-the.. - Windsor C
Understanding-the.. - Windsor C

... • Action potential: when excited, pores open and + ions flow through axon “firing” an electrical pathway to the terminal button – Increase in + ions is called depolarization – the # of ions necessary for “firing” is called the threshold • Once the process starts, it cannot stop: All-ornone principle ...
Chapter 05: Synaptic Transmission
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... packaged in synaptic vesicles. E.g. Amino acids and amines are stored in synaptic vesicles • Large molecules assembled in the cell body, packaged in vesicles, and then transported to the axon terminal. E.g. Peptides are stored in and released from secretory granules  Often coexist in the same axon ...
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... SEQUENCE OF EVENTS [AT CHOLINERGIC SYNAPSE(acetylcholine is neurotransmitter)] 1. Arriving AP depoliarizes the synaptic knob and the presynaptic membrane 2. Ca+2 ions enter the cytoplasm of the synaptic knob – membrane channels in synaptic vesicles – release Ach 3. Ach diffuses across synaptic cleft ...
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Norepinephrine as a neurotransmitter

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Chapter 48 Worksheet
Chapter 48 Worksheet

... b. The concentration of sodium is much higher inside the cell than outside. c. The sodium-potassium pump plays a role in maintaining the resting potential. d. Inside the cell, the concentration of potassium is much higher than the concentration of sodium. e. All of these are true statements. 3. Whic ...
LECTURE11.SynapsesIV
LECTURE11.SynapsesIV

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... - Action potential jumps from one node to the other node - This is called saltatory conduction Saltatory conduction Conduction is passive between nodes some current leaks, and the current decayse exponentially The current that makes it to the next node can trigger an action potential - It must be ab ...
Notes on nervous system and neurons File
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... open and allow Na+ ions to rush inside. This rush of + ions makes the membrane more + than its surroundings (@ +30 to 55 mvolts). Depolarization at the 1st gate must meet a Threshold Potential to cause the next gate to open. Gates must continue to open to continue sending the signal down the entire ...
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... •Cortical Gain Control (Abbott et al.,1997. Science 275, 220-224) •Rhythm Generation (Senn et al., 1996. Neural Networks 9 ,575-588) •Network Resonance (Houweling et al., 2002. J. Physiol 542, 599-617) •Temporal Filtering (Fortune and Rose, 2001. TINS 24, 381-385) ...
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... An  introductory  survey  of    designed  to  provide  a  general  understanding  of  the   nervous  system  including  how  it  functions,  how  it  develops,  and  how  it  changes  with   learning  and  memory.  Analysis  from  the ...
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... • Local disturbances in membrane potential – occur when neuron is stimulated by chemicals, light, heat or mechanical disturbance – depolarization decreases potential across cell membrane due to opening of gated Na+ channels • Na+ rushes in down concentration and electrical gradients • Na+ diffuses f ...
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... F. Nerves and supporting cells that collect information about the body’s environment G. Chemical that transmits an impulse across a synapse to another cell H. Tough, transparent layer of cells through which light enters the eye ...
neurotransmitter
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... released by the brain reward system. Dopamine has multiple functions depending on where in the brain it acts. It is usually inhibitory. ...
The Neural Control of Behavior
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on micro principles
on micro principles

... mV) to 32 mV. Voltage-gated Na+ channels inactivate; voltage-gated K+ channels activate. K+ ions flow out of axon. ...
BOX 2.1 THE NEURON DOCTRINE The cell theory, which states
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... The cell theory, which states that all organisms are composed of individual cells, was developed around the middle of the nineteenth century by Mattias Schleiden and Theodor Schwann. However, this unitary vision of the cellular nature of life was not immediately applied to the nervous system, as mos ...
IV. Conduction Across Synapses
IV. Conduction Across Synapses

... ex: acetylcholine (Ach) split by enzyme acetylcholinesterase (AChE) ...
Neuron Structure and Function
Neuron Structure and Function

...  electrical signal in the presynaptic cell is communicated to the postsynaptic cell by a chemical (the neurotransmitter)  separation between presynaptic and postsynaptic membranes is about 20 to 30 nm  a chemical transmitter is released and diffuses to bind to receptors on postsynaptic side  bin ...
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Chemical synapse



Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body.At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are kept within small sacs called vesicles, and are released into the synaptic cleft by exocytosis. These molecules then bind to receptors on the postsynaptic cell's side of the synaptic cleft. Finally, the neurotransmitters must be cleared from the synapse through one of several potential mechanisms including enzymatic degradation or re-uptake by specific transporters either on the presynaptic cell or possibly by neuroglia to terminate the action of the transmitter.The adult human brain is estimated to contain from 1014 to 5 × 1014 (100–500 trillion) synapses. Every cubic millimeter of cerebral cortex contains roughly a billion (short scale, i.e. 109) of them.The word ""synapse"" comes from ""synaptein"", which Sir Charles Scott Sherrington and colleagues coined from the Greek ""syn-"" (""together"") and ""haptein"" (""to clasp""). Chemical synapses are not the only type of biological synapse: electrical and immunological synapses also exist. Without a qualifier, however, ""synapse"" commonly means chemical synapse.
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