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chapter_12 - The Anatomy Academy
chapter_12 - The Anatomy Academy

... detect changes in body and external environment information transmitted into brain or spinal cord lie between sensory and motor pathways in CNS 90% of our neurons are interneurons process, store and retrieve information ...
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4-6_SynTransRecycofNeurotrans_KotekZs
4-6_SynTransRecycofNeurotrans_KotekZs

... 1.Synthesis and storage: Neurotransmitters must be synthesizes and stored invesicles,so that when an action potential arrives at the nerve ending, the cell is ready to pass it along to the next neuron. There are two main cathegories of neurotransmitters: small-molecule neurotransmitters, synthesised ...
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... the result of an action potential Step 3: The depolarization causes voltage-gated Ca2+ channels to open and allows Ca2+ ions to flow into the terminal Step 4: The resulting increase in Ca2+ triggers fusion of the synaptic vesicles with the presynaptic membrane Step 5: The transmitter is released int ...
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Chemical synapse



Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body.At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are kept within small sacs called vesicles, and are released into the synaptic cleft by exocytosis. These molecules then bind to receptors on the postsynaptic cell's side of the synaptic cleft. Finally, the neurotransmitters must be cleared from the synapse through one of several potential mechanisms including enzymatic degradation or re-uptake by specific transporters either on the presynaptic cell or possibly by neuroglia to terminate the action of the transmitter.The adult human brain is estimated to contain from 1014 to 5 × 1014 (100–500 trillion) synapses. Every cubic millimeter of cerebral cortex contains roughly a billion (short scale, i.e. 109) of them.The word ""synapse"" comes from ""synaptein"", which Sir Charles Scott Sherrington and colleagues coined from the Greek ""syn-"" (""together"") and ""haptein"" (""to clasp""). Chemical synapses are not the only type of biological synapse: electrical and immunological synapses also exist. Without a qualifier, however, ""synapse"" commonly means chemical synapse.
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