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The Synapse
The Synapse

... membrane retrieved from the plasmalemma through endocytosis. ...
`synapse`.
`synapse`.

... Impulse from the action potential opens ion channels for Ca++ The increased Ca++ concentration in the axon terminal initiates the release of the neurotransmitter (NT) NT is released from its vesicle and crosses the “gap” or synaptic cleft and attaches to a protein receptor on the dendrite ...
Synapse
Synapse

... conducted along the axon (anterograde flow). The NT can be inhibitory or excitatory. • Synaptic cleft or gap: is app. 20nm. It is a non-anatomical continuity between the post and pre-synaptic ends. • Postsynaptic terminal: is the name given to the last part of the synapse. It is usually comprised of ...
Synapse - MBBS Students Club
Synapse - MBBS Students Club

... conducted along the axon (anterograde flow). The NT can be inhibitory or excitatory. • Synaptic cleft or gap: is app. 20nm. It is a non-anatomical continuity between the post and pre-synaptic ends. • Postsynaptic terminal: is the name given to the last part of the synapse. It is usually comprised of ...
CBNS 106 Review
CBNS 106 Review

... – Excitatory vs. inhibitory synapses: Bind different neurotransmitters, allow different ions to pass through channels – Membrane potential less negative than -65mV = hyperpolarizing IPSP ...
presentation source
presentation source

... • The signal travels passively as an electrical current between Nodes. • The thick myelin insulation of the Internode allows the local circuit current to spread much further and faster than in un-myelinated fibres ...
Synapses - Franklin College
Synapses - Franklin College

... and another neuron or effector (muscle or gland). ...
Synaptic Transmission
Synaptic Transmission

... Synapse = the junction between two neurons where a nerve impulse is transmitted. ...
File
File

... conducted along the axon (anterograde flow). The NT can be inhibitory or excitatory. • Synaptic cleft or gap: is app. 20nm. It is a non-anatomical continuity between the post and pre-synaptic ends. • Postsynaptic terminal: is the name given to the last part of the synapse. It is usually comprised of ...
Synapses and neurotransmitters
Synapses and neurotransmitters

... Binding site Ion channel One neuron (usually) has only one type of receptor • Great place for drug interaction ...
chapter 3: biological bases of behavior
chapter 3: biological bases of behavior

... Neuron either fires or doesn’t  Action potentials are all the same size  Rate of action potentials tells strength of stimuli  Size of axon effects rate ...
5-2_NeurotransmRelease_BenseM
5-2_NeurotransmRelease_BenseM

... of the affected cells. Main stages of neurotransmitter release: 1. When the action potential comes down the axon and reaches the axon terminal, the membrane potential will change 2. This change will open voltage-gated Ca2+ channels, that let the Ca2+ flow in 3. This transport happens because of the ...
Document
Document

... Irregular contours, appendages (spines) Originates as thick, tapering process Ramifies by branching at acute angles Subdivides into smaller branches Confined to the vicinitiy of cell body Microtubules predominate in dendrites Conduct in a decremental fashion but may be capable of generating action p ...
01 Physiology of Synaptic Transmission
01 Physiology of Synaptic Transmission

... (1) define synapses and show where they are located . (2) describe the parts of a synapse , & what does each part contain . (3) know how to classify synapses . (4) define synaptic transmitters , give examples of excitatory & inhibitory ones ; explain how they are released (5) explain ionic channels ...
Action Potentials
Action Potentials

... “Each neuron continuously integrates signals over both time and space as it is continually bombarded with stimuli through the thousands of synapses covering its dendrites and cell body. Remember that, although schematic diagrams of neural circuitry rarely show neurons with more than a few representa ...
steps in nerve impulse transmission
steps in nerve impulse transmission

...  K channels open and let K rush out  Na stays in since gate is closed (down to -80mV) (extra dip is refractory period) ...
Neurotransmitter receptors and reuptake
Neurotransmitter receptors and reuptake

Synapse - Mayfield City Schools
Synapse - Mayfield City Schools

... Presynaptic neuron- carries impulse towards a synapse “Sender” Postsynaptic neuron- carries impulse away from a synapse “receiver” ...
Chapter 5
Chapter 5

... • VG Ca++ channels open. • Ca++ enters bouton down concentration gradient. • Ca++ activates calmodulin, which activates protein kinase. ...
Synaptic transmission
Synaptic transmission

... Central nervous system synapses • Though there are two types( chemical and electrical), but, since almost all the synapses un CNS are chemical synapses, so these are discussed in detail. • In these, the first neuron secretes at its nerve ending synapse a chemical substance called a neurotransmitter ...
Neural Control II
Neural Control II

... – Electrical synapses – involve direct cytoplasmic connections between the two cells formed by gap junctions; the gap junctions allow ion currents to continue; relatively rare in vertebrates – Chemical synapses – electrical impulses must be converted to a chemical signal that crosses the synapse; mo ...
Neurons - Jordan High School
Neurons - Jordan High School

... Action potential begins between -60 & -55 mV (threshold) Stimulus triggers action potential, or not at all if doesn’t meet threshold ...
48 - Groupfusion.net
48 - Groupfusion.net

... inhibitory neurotransmitter from a presynaptic cell to a postsynaptic receptor; makes it more difficult for a for a postsynaptic neuron to generate an action potential. ...
Nervous Systems
Nervous Systems

... The anatomy of a neuron. The mechanisms of impulse transmission in a neuron. The process that leads to release of neurotransmitters, and what happens at the synapse. ...
Ch 48: Nervous System – part 1
Ch 48: Nervous System – part 1

... How do action potentials “travel” along an axon?  the strong depolarization of one action potential assures that the neighboring region of the neuron will be depolarized above threshold, triggering a new action potential, and so on…  SYNAPSE: junction between a neuron and another cell; found betwe ...
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Chemical synapse



Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body.At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are kept within small sacs called vesicles, and are released into the synaptic cleft by exocytosis. These molecules then bind to receptors on the postsynaptic cell's side of the synaptic cleft. Finally, the neurotransmitters must be cleared from the synapse through one of several potential mechanisms including enzymatic degradation or re-uptake by specific transporters either on the presynaptic cell or possibly by neuroglia to terminate the action of the transmitter.The adult human brain is estimated to contain from 1014 to 5 × 1014 (100–500 trillion) synapses. Every cubic millimeter of cerebral cortex contains roughly a billion (short scale, i.e. 109) of them.The word ""synapse"" comes from ""synaptein"", which Sir Charles Scott Sherrington and colleagues coined from the Greek ""syn-"" (""together"") and ""haptein"" (""to clasp""). Chemical synapses are not the only type of biological synapse: electrical and immunological synapses also exist. Without a qualifier, however, ""synapse"" commonly means chemical synapse.
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