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Insights into decision making using choice probability
Insights into decision making using choice probability

... the second question includes a tacit assumption that CP originates from feedforward mechanisms. Recent work on CP calls this assumption into question. Therefore, we also ask, 3) what is the origin of CP?; does it result from feedforward pooling of neuronal activity or from feedback mechanisms such a ...
Inhibition of central neurons is reduced following acoustic trauma
Inhibition of central neurons is reduced following acoustic trauma

... DCN of unexposed animals. Instead, neurons showed no response to sound, weak responses that were hard to tune and characterize, or ‘‘tail’’ responses, consisting of broadly-tuned, predominantly excitatory responses, with a roughly low-pass shape similar to the tuning curves of auditory nerve fibers ...
the superior Olivary complex
the superior Olivary complex

... of the MOC neuron (Liberman & Brown, 1986). The marginal cell region of the anteroventral cochlear nucleus (AVCN) project bilaterally to MOC neurons. It is hypothesized that the marginal cells provide information about sound intensity as part of a feedback gain control system comprising the cochlea, ...
PARK9-Associated ATP13A2 Localizes to Intracellular
PARK9-Associated ATP13A2 Localizes to Intracellular

... ATP13A2 loss-of-function on the viability and integrity of dopaminergic neurons, we employed mir-30adapted short hairpin RNA (shRNA) constructs to silence the expression of endogenous ATP13A2. To validate shRNA constructs, we demonstrate by Western blot analysis the successful knockdown of fulllengt ...
Use of an Amino-Cupric-Silver Technique for the Detection of Early
Use of an Amino-Cupric-Silver Technique for the Detection of Early

... stored in fixative for 2-3 days. Good results, however, have been obtained in sections that have been postfixed for only 25 h or at the other extreme for 2-3 months in a refrigerator (4°C). The postfixation eventually suppresses normal fiber staining; at 24 h some normal fibers will be stained, whil ...
Glycine Immunoreactivity of Multipolar Neurons in the Ventral
Glycine Immunoreactivity of Multipolar Neurons in the Ventral

... and Young, 1980; Young et al., 1988). These local circuits, however, do not account for all of the response properties of DCN neurons. For example, type II units of the DCN are relatively unresponsive to broadband stimuli even when the stimuli contain energy within the excitatory response area of th ...
For Peer Review - diss.fu
For Peer Review - diss.fu

... The bilateral habenular nucleus of the epithalamus consists of a medial (MHb) and a lateral (LHb) complex. Both parts receive input from structures such as lateral hypothalamus, lateral preoptic area, entopeduncular nucleus and basal ganglia via the stria medularis and the medial forebrain bundle (H ...
Production and Survival of Projection Neurons in a Forebrain Vocal
Production and Survival of Projection Neurons in a Forebrain Vocal

... completely scanned for 3H-labeled neurons. The number of such cells that were also retrogradely labeled with beads was divided by the volume sampled to generate double-labeled cell densities. )H-bead cell density data were used for comparing the efficacy of beads and fluorogold. Ventricular zone ana ...
The Central Nervous System
The Central Nervous System

... The brain, a large mass of neural tissue, contains internal passageways and chambers filled with CSF. The six major regions of the brain have specific functions. As you ascend from the medulla oblongata to the cerebrum, those functions become more complex and variable. Conscious thought and intellig ...
Central Nervous System
Central Nervous System

... 5 Repolarization. Potassium ions diffuse out of the cell as the membrane permeability changes again, restoring the negative charge on the inside of the membrane and the positive charge on the outside surface. Repolarization occurs in the same direction as depolarization. ...
PDF version - UTRGV Faculty Web
PDF version - UTRGV Faculty Web

... complied with the animal care guidelines of the University of Melbourne and the laws of Australia. Animals were anaesthetised by chilling for at least 30 minutes before dissection. Dissections were performed in chilled seawater. I removed the abdomen at the thoracicabdomen joint, trimmed the protrud ...
The limbic system
The limbic system

... cause stimulation of various parts of the hypothalamus, especially the lateral areas and produce diffuse sympathetic discharge. The massive sympathetic discharge during stress is called the “flight or fright response”. Stress via cortical and limbic connections causes release of corticotropin­releas ...
Primate Globus Pallidus and Subthalamic Nucleus: Functional
Primate Globus Pallidus and Subthalamic Nucleus: Functional

... numbers caudally. In the central portions the anatomical/physiological basis of the they were situated largely inferior and lateral symptoms of basal ganglia dysfunction in to leg movement-related neurons. Neurons humans. SUMMARY ...
Neural and Computational Mechanisms of Action Processing
Neural and Computational Mechanisms of Action Processing

... underlying computations remains rather limited. This fact stands in contrast with a wide variety of speculative theories about how action recognition might work, and how it might interact with other cognitive brain functions. This review focuses on new fundamental electrophysiological results in mon ...
Mirror neurons or emulator neurons?
Mirror neurons or emulator neurons?

... account (Fig. 1a) postulates a new entry point to the motor loop during action observation. This new entry point is the mirror system, which duplicates the motor command necessary for the observed action by 'direct matching', bypassing the normal route through the motor controller (the inverse model ...
Aminobutyric Acid (GABA)-A Function and Binding in
Aminobutyric Acid (GABA)-A Function and Binding in

... a tonic GABAergic inhibition on sympathoadrenal function from several forebrain sites.11,29 A role for GABA has been strongly implicated in hypertension. Administration of GABA agonists intraventricularly causes a greater fall in blood pressure in hypertensive animals.21,22,30 Muscimol microinjectio ...
Cough, Expiration and Aspiration Reflexes following
Cough, Expiration and Aspiration Reflexes following

... groups containing pools of neurons being activated during the stimulation of cough trigger zones within the airways. In addition, the terminal arborization of neurons from the commissural subnucleus of the nucleus tractus solitarii (the region which receives vagal primary afferents from the lungs, a ...
The Impact of Prior Experience With Cross-Modal
The Impact of Prior Experience With Cross-Modal

... accurately (Stein, Meredith, Huneycutt, & McDade, 1989), simultaneous presentation of light and sound from different spatial locations can depress activity in neurons responsive to multiple sensory inputs (Binns, Turner, & Salt, 1999), which may attenuate behavior. The neurons responsible for MI are ...
Chapter 6 — Gross Anatomy of the Brain
Chapter 6 — Gross Anatomy of the Brain

... ventricles, which communicate with the third ventricle via the interventricular foramen (foramen of Monro) (Fig. 6.2A). The two lateral ventricles are separated from one another by two closely adjoined non-nervous membranes, each known as a septum pellucidum. Ependymal cells line each lateral ventri ...
DOWN - Ubiquitous Computing Lab
DOWN - Ubiquitous Computing Lab

... INT Winner; /* - last winner in Kohonen layer */ REAL Alpha; /* - learning rate for Kohonen layer */ REAL Alpha_; /* - learning rate for output layer */ REAL Alpha__; /* - learning rate for step sizes */ ...
Activity of Defined Mushroom Body Output Neurons
Activity of Defined Mushroom Body Output Neurons

... S2). Lastly, R66C08-GAL4 only expresses in the M6/MBONg5b0 2a neurons that mostly innervate the g lobe tip and the anterior zone of b0 2 (Figure 1C, Movie S3). We determined the polarity of the M4/6 neurons using expression of established neural compartment marker proteins. The dendritic marker DenM ...
Webb et al 2002 - User Web Areas at the University of York
Webb et al 2002 - User Web Areas at the University of York

... How does feedback from V1 and extraclassical stimulation modulate the activity of LGN neurons? To investigate the influence that feedback from the striate cortex has over extraclassical interactions in the LGN, we measured the modulated response of LGN neurons to gratings of a range of different con ...
Conversion of Mouse and Human Fibroblasts into Functional Spinal
Conversion of Mouse and Human Fibroblasts into Functional Spinal

... reprogram fibroblasts into spinal motor neurons. Motor neurons control the contraction of muscle fibers actuating movement. Damage to motor neurons caused by either injury or disease can result in paralysis or death; consequently, there is significant interest in understanding how motor neurons rege ...
Motor Cortical Networks for Skilled Movements Have Reaching
Motor Cortical Networks for Skilled Movements Have Reaching

... defined as the average firing rate of a neuron during control periods (when the animal was sitting quietly) (Figures 1(a) and 1(b)). Analysis of spike duration was performed using the “Spike2” software package (CED, Cambridge, UK), and spike duration was determined using the distance between the two ...
Rhythmicity, randomness and synchrony in climbing fiber signals
Rhythmicity, randomness and synchrony in climbing fiber signals

... indicated by multiple peaks in autocorrelograms. These results suggest that any input to the inferior olive, whether it is inhibitory (GABA) or excitatory (glutamate), suppresses rhythmicity. The inferior olive receives abundant GABAergic inputs from the cerebellar nuclei, and excitatory inputs from ...
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Circumventricular organs

Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function. The lack of a blood brain barrier allows the CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances. CVOs can be classified into (a) sensory and (b) secretory organs. The sensory organs include the area postrema (AP), the subfornical organ (SFO) and the vascular organ of lamina terminalis. They have the ability to sense plasma molecules and then pass that information into other regions of the brain. Through this, they provide direct information to the autonomic nervous system from the systemic circulation. The secretory organs include the subcommissural organ (SCO), the posterior pituitary, the pineal gland, the median eminence and the intermediate lobe of the pituitary gland. These organs are responsible for secreting hormones and glycoproteins into the peripheral vascular system using feedback from both the brain environment and external stimuli.All of the circumventricular organs, besides the SCO, contain extensive vasculature and fenestrated capillaries which leads to a ‘leaky’ BBB at the site of the organs. Furthermore, all CVOs contain neural tissue, allowing them to play a role in the neuroendocrine system. It is highly debated if the choroid plexus can be included as a CVO. It has a high concentration of fenestrated capillaries, but its lack of neural tissue and its primary role of producing cerebrospinal fluid (CSF) usually excludes the choroid plexus from the CVO classification.Research has also linked CVOs to body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.
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