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Long lnterfascicular Axon Growth from Embryonic Neurons
Long lnterfascicular Axon Growth from Embryonic Neurons

... series in Davies et al., 1993) lay farther back and laterally at the level of the hippocampal flexure. This transplant straddled the boundary between the fimbria and stria terminalis, with some donor cells in both tracts. The transplanted cells gave rise to two narrow beams of axons, one in the fimb ...
superior Medullary Velum
superior Medullary Velum

... interpeduncular fossa, cerebral peduncle, midbrain, cerebellar cortex, inferior colliculus, lingula and vermis is reported to be from the vermian artery originating from the posterior cerebral artery (25). We did not study the vascular anatomy and only fiber dissection and immunohistochemical analys ...
Neuronal Correlates of Sensorimotor Association in Stimulus
Neuronal Correlates of Sensorimotor Association in Stimulus

... 1989; Miller, Riehle, & Requin, 1992) that MI neurons may be classified according to the timing properties of their activity. "Sensorimotor" neurons in particular display two successive activity components, one stimulus related and the other movement related. These neurons therefore seemed to be goo ...
Some Fiber Projections to the Superior Colliculus in the Cat`
Some Fiber Projections to the Superior Colliculus in the Cat`

... Degenerated fibers were observed in all animals in the pretectum, though the number of degenerated fibers was considerably greater in those animals which had ventrally placed geniculate lesions. These degenerated fibers reached the pretectum by way of the medial aspect of the optic tract and the lat ...
AP150 PATHWAYS ASSIGNMENT
AP150 PATHWAYS ASSIGNMENT

... An action potential begins on a ___UPPER MOTOR_ neurons that leaves the __FRONTAL__ lobe of the brain and passes through the ____CEREBRAL PENDUNCLES__ of the midbrain and then the __PYRAMIDS__ of the medulla oblongata where it then decussates and travels down a __ANTERIOR OR LATTERAL __ column to th ...
OSBP coupled with ER-resident protein FAN is essential
OSBP coupled with ER-resident protein FAN is essential

... within which cholesterol molecules are embedded. The distribution of both phospholipids and cholesterol in cellular membranes is distinct and highly dynamic. Phospholipids are asymmetrically distributed in the leaflets of many bilayer membranes, including the plasma membrane, the endosomal membrane, ...
ORGANIZATION OF NEUROPIL
ORGANIZATION OF NEUROPIL

... fourth and final division is the central neuropil, the neuron feltwork. In many cases it represents the major portion of the ganglion. The term neuropil, however, has beef, used in different ways by a number of authors, and is not a precisely defined concept (see Herrick, 1948; Dempsey and Luse, 195 ...
Figure 1 - Journal of Neuroscience
Figure 1 - Journal of Neuroscience

... fluorescently labeled electrode track. D, Labeled track through the posterior right BIN in a different marmoset (18W) using a lateral electrode approach. E, A far anterior section of the right BIN from 18W also showing the SC, medial geniculate body (MGB), and the parabigeminal nucleus (PBG). The tr ...
Tactile orientation perception: an ideal observer analysis of human
Tactile orientation perception: an ideal observer analysis of human

... have elliptical RFs (Pruszynski and Johansson 2014; VegaBermudez and Johnson 1999) with aspect ratios that are similar, on average, to those of S1 cortical neurons (Sripati et al. 2006b). Elongated RFs, however, seem to be somewhat more prevalent in cortex than in the periphery. Sripati et al. (2006 ...
Hippocampal CA1 pyramidal cells form functionally
Hippocampal CA1 pyramidal cells form functionally

... Although the molecular, anatomical and functional diversity of ­cortical interneurons is well documented1–3, principal cells are typically grouped together on the basis of their cortical layer and/or subregion assignments. However, several recent observations have suggested that there are distinct s ...
The Big Picture File
The Big Picture File

... or pressure on organs/blood vessels ...
the evolution of body and brain, and of sensory
the evolution of body and brain, and of sensory

... prosimians. Whereas the largest prosimians, like the ring-tailed lemur or the aye-aye, weigh no more than about 3 kg, the male long-tailed macaque may weigh up to 12 kg, the Hanuman langur 20 kg, the chacma baboon 30 kg, and the olive baboon and mandrill 37 kg (Burnie and Wilson, 2001). New World mo ...
2011-Morrison and Nakamura_review
2011-Morrison and Nakamura_review

... which cutaneous and visceral cold and warm sensation and/or reductions or elevations in brain temperature elicit changes in thermoregulatory effector tissues to counter or protect against changes in the temperature of the brain and other critical organ tissues. The effector mechanisms for cold defen ...
Move to the rhythm: oscillations in the subthalamic nucleus–external
Move to the rhythm: oscillations in the subthalamic nucleus–external

... are in green. Brainstem premotor nuclei and midbrain nuclei, which use a variety of neurotransmitters, are shaded gray. The major afferents to the basal ganglia are from the cortex and thalamus and are directed to both the striatum and the subthalamic nucleus (STN). The striatum influences the basal ...
Appetitive associative learning recruits a distinct
Appetitive associative learning recruits a distinct

... basolateral amygdalar nucleus, anterior part; CP, caudoputamen; CS, conditioned stimulus; *DLS, dorsolateral striatum; DMH, dorsomedial hypothalamic nucleus; *DMS, dorsomedial striatum; ILA, infralimbic area; IR, immunoreactive; KPBS, potassium phosphate-buffered saline; LHA, lateral hypothalamic are ...
Parallel basal ganglia circuits for voluntary and
Parallel basal ganglia circuits for voluntary and

... However, animals and humans with basal ganglia dysfunctions show deficits that may not simply be classified as movement disorders. For example, animals with large lesions in the striatum may ignore a moving object or obsessively follow it (Denny-Brown, 1962). Patients with Parkinson’s disease may have ...
Sample
Sample

... Briefly describe the meaning of the HPG axis. Answer: The letters H-P-G stand for hypothalamus, pituitary gland, and gonads which work together to form a feedback system that monitors levels of hormones in the body and attempts to keep them at a consistent level. The hypothalamus monitors levels of ...
Synaptic Targets of Medial Septal Projections in the Hippocampus
Synaptic Targets of Medial Septal Projections in the Hippocampus

... Temporal coordination of neuronal assemblies among cortical areas is essential for behavioral performance. GABAergic projections from the medial septum and diagonal band complex exclusively innervate GABAergic interneurons in the rat hippocampus, contributing to the coordination of neuronal activity ...
Dopamine neurons projecting to the posterior striatum form an
Dopamine neurons projecting to the posterior striatum form an

... As previously reported, we found that dopamine neurons with distinct projection targets reside in different, but overlapping, areas of the midbrain (Figure 3; Figure 3-figure supplement 1; Figure 3-figure supplement 2; Figure 3-figure supplement 3) (Bjorklund and Dunnett, 2007; Haber, 2014; Lammel e ...
Projections of the amygdala to the thalamus in the cynomolgus
Projections of the amygdala to the thalamus in the cynomolgus

... concentrations of these labelled cells occurred in the medial nucleus and in the medial portion of the central nucleus. The remaining amygdaloid nuclei contained only a handful of labelled cells, with an occasional cell being present in each amygdaloid nucleus (Fig. 4). A similar anterior thalamic i ...
Leptin: A metabolic signal affecting central regulation of
Leptin: A metabolic signal affecting central regulation of

... Intracerebroventricular administration of leptin failed to stimulated LH secretion in the intact prepubertal gilt [19], but did suppress feed intake [25]. However, leptin administration occurred during the period of heighten negative feedback action of estradiol on LH secretion [2], thereby blocking ...
PDF Document
PDF Document

... ing broad areas of illumination. Opsin expression over long distances may be required because of the trials that use viral vectors to deliver othlength of axons in the spinal cord and peripheral nervous system. Outside of the spinal cord and brain, the er types of therapeutic genes are under immune ...
Genetic Analysis of Brain Circuits Underlying Pheromone Signaling
Genetic Analysis of Brain Circuits Underlying Pheromone Signaling

... mitral cells. Decades of investigation have pointed to sharp contrasts in the functional characteristics of the two olfactory structures and associated neural pathways (23, 24). Classical retrograde and anterograde tracing studies have evidenced the distinct central networks forming the vomeronasal ...
Stimulation of Medial Prefrontal Cortex Decreases
Stimulation of Medial Prefrontal Cortex Decreases

... 1985). A similar antidromic response latency of 20.9 ⫾ 1.5 msec was observed for BL neurons after stimulation of mPFC. As the electrode descended through CeM and then BL, there was an abrupt transition in the ability to antidromically activate cells, first from the brainstem and then from mPFC (Fig. ...
Altered Patterns of Dynorphin lmmunoreactivity Suggest
Altered Patterns of Dynorphin lmmunoreactivity Suggest

... junction of CA3 and CA2 (arrow). No specific staining is evident in the granule cell (G) layer or supragranular region of the molecular (M) layer. Scale bar, 500 pm. B, Within the polymorph layer, reaction product is concentrated in clumps (arrowheads) of punctate structures near the proximal portio ...
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Circumventricular organs

Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function. The lack of a blood brain barrier allows the CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances. CVOs can be classified into (a) sensory and (b) secretory organs. The sensory organs include the area postrema (AP), the subfornical organ (SFO) and the vascular organ of lamina terminalis. They have the ability to sense plasma molecules and then pass that information into other regions of the brain. Through this, they provide direct information to the autonomic nervous system from the systemic circulation. The secretory organs include the subcommissural organ (SCO), the posterior pituitary, the pineal gland, the median eminence and the intermediate lobe of the pituitary gland. These organs are responsible for secreting hormones and glycoproteins into the peripheral vascular system using feedback from both the brain environment and external stimuli.All of the circumventricular organs, besides the SCO, contain extensive vasculature and fenestrated capillaries which leads to a ‘leaky’ BBB at the site of the organs. Furthermore, all CVOs contain neural tissue, allowing them to play a role in the neuroendocrine system. It is highly debated if the choroid plexus can be included as a CVO. It has a high concentration of fenestrated capillaries, but its lack of neural tissue and its primary role of producing cerebrospinal fluid (CSF) usually excludes the choroid plexus from the CVO classification.Research has also linked CVOs to body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.
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