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The role of the cerebellum in classical conditioning of
The role of the cerebellum in classical conditioning of

... The CR and the unconditioned response (UR) are similar in eye-blink conditioning in the sense that to a large extent the same muscles and motor nuclei are engaged. However, the CR and the UR differ fundamentally in a number of respects. The minimum onset latency of the CR to a tone CS in well-traine ...
the resonate-and-fire neuron: time dependent and frequency
the resonate-and-fire neuron: time dependent and frequency

... main conducting unit of a neuron and it conveys information to other neurons (postsynaptic neurons) by propagating action potentials. Unlike the attenuated signals that traverse the dendritic tree, the action potential is not attenuated as it traverses the axon. Underlying the mechanism of action po ...
Vestibular Signals in the Parasolitary Nucleus
Vestibular Signals in the Parasolitary Nucleus

... Barmack, N. H. and V. Yakhnitsa. Vestibular signals in the parasolitary nucleus. J Neurophysiol 83: 3559 –3569, 2000. Vestibular primary afferents project to secondary vestibular neurons located in the vestibular complex. Vestibular primary afferents also project to the uvula-nodulus of the cerebell ...
- Columbia University Medical Center
- Columbia University Medical Center

... during the development of the vertebrate central nervous system (CNS)—a diversity essential to the formation of selective neuronal circuits. Soon after their generation, neurons of a particular class segregate from those of other classes—a process that is linked to their later patterns of connectivi ...
Five Sources of a Dorsal Root Potential: Their Interactions and
Five Sources of a Dorsal Root Potential: Their Interactions and

... LISSAUER TRACT. Stimuli were delivered through Merrill-Ainsworth (1972)-type glass-coated tungsten microelectrodes with 25mm exposed tips. The electrode was placed in a micromanipulator on the surface of the Lissauer tract usually between L2 and L3 where the Lissauer tract is most easily accessible ...
On-line Optical Operant Conditioning of Cortical Activity
On-line Optical Operant Conditioning of Cortical Activity

... Figure  5.4  Event-­‐triggered  averages  of  calcium  signals    ...................................................  80   Figure  5.5  Effects  of  the  relationships  between  target  and  non-­‐target  neurons    ...  82   Figure  5.6  Probabil ...
Dateien anzeigen - Universität Düsseldorf
Dateien anzeigen - Universität Düsseldorf

... McConnell, 1995; Haydar et al., 2003; Noctor et al., 2004). The Drosophila NB, as well as sensory organ precursor cells in the Drosophila peripheral nervous system and the C. elegans zygote, has served as a good model system to investigate asymmetric cell division. The advantages of using Drosophila ...
THE REGULATION OF SLEEP AND WAKEFULNESS BY THE
THE REGULATION OF SLEEP AND WAKEFULNESS BY THE

... to narcolepsy. Additionally, it has been reported that the number of orexin neurons is greatly reduced and that orexin peptide levels are decreased to undetectable levels in the cerebrospinal fluid of narcoleptic patients4-6). Orexin/ataxin-3 mice are a well-studied model for narcolepsy; however, or ...
A transcription factor network controls cell migration
A transcription factor network controls cell migration

... order to establish precise connectivity patterns (for a review, see Guillemot, 2007). However, the exact mechanisms that fine-tune the specification of the myriad of neuronal subtypes remain unknown. This is exemplified by cell-type specification in vertebrate retinal development, during which one g ...
Kobayashi S, Kawagoe R, Takikawa Y, Koizumi M, Sakagami M
Kobayashi S, Kawagoe R, Takikawa Y, Koizumi M, Sakagami M

... and KI). When the neuron had spatial preference, one of the two positions was selected to be within the neuron’s response field. The monkey had to remember the cue position during a delay period of random duration between 0.9 and 2.1 s for monkeys HA and ZO and between 1.0 and 1.5 s for monkeys GA, ...

 Program
and
Abstracts
from
the
Fifth
Annual
Canadian
Neuroscience
Meeting
 May
29
–
June
1
2011
 Quebec
City
Convention
Center


 Program
and
Abstracts
from
the
Fifth
Annual
Canadian
Neuroscience
Meeting
 May
29
–
June
1
2011
 Quebec
City
Convention
Center


... precursors
leave
the
SVZ
every
day
bound
to
the
olfactory
bulb
(OB),
in
a
process
known
as
adult
 neurogenesis.
Intensive
investigation
has
revealed
myriad
molecular
cues
involved
in
this
form
of
 neurogenesis,
however
molecules
signaling
exclusively
for
adult
neurogenesis
are
yet
to
be
 described.
 ...
Dopamine Receptor–Mediated Mechanisms Involved in the
Dopamine Receptor–Mediated Mechanisms Involved in the

... performing behavioral tasks. In experiment 1, a monkey was trained to associate a click sound with a drop of reward water. DA receptor antagonists were administered by micropressure using a stainless steel injection cannula (300 mm ID) through which a Teflon-coated tungsten wire for recording neuron ...
Local network regulation of orexin neurons in the lateral hypothalamus
Local network regulation of orexin neurons in the lateral hypothalamus

... Many of orexin’s known behavioral effects, such as stimulation of food intake, wheel running, and spontaneous physical activity can be induced by local injection of orexins into the LH/PFA (27, 60, 61, 79, 111, 113, 116, 125). An orexin injection into the LH/PFA also results in Fos expression, a mar ...
Contrasting Effects of Reward Expectation on Sensory and Motor
Contrasting Effects of Reward Expectation on Sensory and Motor

... The eye positions from the camera were converted to digital signals at 250 Hz. One computer controlled the tasks and the other monitored neuronal activity, eye position, and task events. The activity of single neurons was recorded with glass-insulated elgiloy microelectrodes (impedance, 0.3--1.5 MX) ...
Image-based Screening Identifies Novel Roles for I B Kinase and
Image-based Screening Identifies Novel Roles for I B Kinase and

Neural Mechanisms of Reflex Reversal in Coxo
Neural Mechanisms of Reflex Reversal in Coxo

... pool itself where gating could take place (Lund et al. 1981). In this study, we focused on the Dep MN pool, because of its accessibility and its small number of well-localized neurons, to investigate the last two levels. We have established a wiring diagram based on systematic intracellular recordin ...
THESIS D - Krishikosh
THESIS D - Krishikosh

... and well wishes, I want to preserve a special love for my relatives and well wishers, which enable me to complete the entire research program successfully. I would always remember the invaluable help, active cooperation and constant inspiration of my wife Dr. Sanjivani and my lovely son Arjun who ma ...
Module 10 - Neuronal Signalling
Module 10 - Neuronal Signalling

... characterizes the brain rhythms detected by electroencephalograms (EEGs). Any consideration of synaptic transmission must take into account the fact that the rate of synaptic transmission is often extremely high. Another example of the significance of timing concerns neuronal coincident detection, d ...
Cystatin C prevents degeneration of rat nigral dopaminergic neurons
Cystatin C prevents degeneration of rat nigral dopaminergic neurons

... et al., 2000). Involvement of cystatin C in various degenerative processes in the central nervous system (CNS) was only relatively recently described. Delayed expression of cystatin C by CA1 pyramidal cells and reactive astrocytes of rat hippocampus was reported in transient forebrain ischemia (Ishi ...
Intrinsic and synaptic plasticity in the vestibular system
Intrinsic and synaptic plasticity in the vestibular system

... calmodulin-dependent protein kinase II (CaMKII) [52]. In spontaneously firing vestibular nucleus neurons, CaMKII activity is maintained at near maximal levels by calcium influx that occurs with each action potential: decreases in CaMKII activity oppose excitability by reducing BK currents. This un ...
indirect projections from the suprachiasmatic nucleus to major
indirect projections from the suprachiasmatic nucleus to major

... differences were noted among the cases with different survival periods. All experiments were performed in compliance with the guidelines established by the Canadian Council on Animal Care and by the Dalhousie University Committee on Laboratory Animals. All efforts were made to minimize the number of ...
Time-Dependent Activation of Feed-Forward Inhibition in
Time-Dependent Activation of Feed-Forward Inhibition in

... intracellular recordings from the LGMD in response to a looming stimulus (l/!v! & 30 ms, illustrated in the top panels) are shown at the bottom. The recordings on the left and right were obtained before and after focal pressure ejection of picrotoxin on the dorsal lobula, respectively. The 2 extrace ...
PDF
PDF

... murine proNGF on the survival of these neurons cultured at low density at stages throughout late fetal and early postnatal development when these neurons are dependent on a supply of mNGF from their targets for survival. In control cultures (no added factors), the majority of neurons died within 48 ...
Rostral Fastigial Nucleus Activity in the Alert Monkey During Three
Rostral Fastigial Nucleus Activity in the Alert Monkey During Three

... Siebold, C., L. Glonti, S. Glasauer, and U. Büttner. Rostral fastigial nucleus activity in the alert monkey during three-dimensional passive head movements. J. Neurophysiol. 77: 1432–1446, 1997. The fastigial nucleus (FN) receives vestibular information predominantly from Purkinje cells of the verm ...
Short title: Thalamocortical computations during tactile sensation
Short title: Thalamocortical computations during tactile sensation

... Dept. of Biological Sciences, Neurobiology Section, University of Southern California, Los Angeles, ...
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Electrophysiology



Electrophysiology (from Greek ἥλεκτρον, ēlektron, ""amber"" [see the etymology of ""electron""]; φύσις, physis, ""nature, origin""; and -λογία, -logia) is the study of the electrical properties of biological cells and tissues. It involves measurements of voltage change or electric current on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and particularly action potential activity. Recordings of large-scale electric signals from the nervous system such as electroencephalography, may also be referred to as electrophysiological recordings.
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