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Nervous System
Nervous System

...  Impulses travel faster when fibers have a myelin sheath ...
Interactions Between Premotor and Motor Cortices in Non
Interactions Between Premotor and Motor Cortices in Non

... The highly-cited review by Jeannerod and his colleagues (549 citations in mid-2011) opened up a new approach to the study of cortical processing, no longer based on the properties of particular cortical areas, but focused on the transmission of information between areas: They suggested that ‘‘the tr ...
Sense Organs - mohamadtermos
Sense Organs - mohamadtermos

... Your taste buds have receptors for different kinds of chemicals: sugar, salt, sours, and bitters. This diagram shows how a sugar molecule can enter a taste bud and bind to an ion channel in the membrane of a receptor cell. The receptor cell then sends neurotransmitters to activate the sensory neuron ...
Bounded Integration in Parietal Cortex Underlies
Bounded Integration in Parietal Cortex Underlies

... A linear motion filter is constructed by adding appropriate combinations of the figj. For example, f1g1 ) f2g2 and f2g1 ( f1g2 pass motion in the )x direction. These two linear filters are in space-time quadrature. They were convolved with the three-dimensional spatiotemporal pattern of the dynamic ...
Nervous_System_Brain
Nervous_System_Brain

... around most long axons ...
Physiological changes in pregnancy
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... • Changes in pregnancy result in an overcompensation to this respiratory demand. The resulting hyperventilation causes the arterial oxygen tension to increase and arterial carbon dioxide tension to fall, accompanied by a compensatory fall in serum bicarbonate. A mild respiratory alkalosis is theref ...
Five Sources of a Dorsal Root Potential: Their Interactions and
Five Sources of a Dorsal Root Potential: Their Interactions and

... separated by 5 mm. The stimulus ( °10 mA, 200 ms, 1 Hz) was a single shock sufficient to produce a maximal DRP on the L6 dorsal root. GASTROCNEMIUS NERVE. The lateral and medial nerves to gastrocnemius were dissected separately in the popliteal fossa, cut, and freed of connective tissue up to the sc ...
Labeled lines meet and talk: population coding of somatic sensations
Labeled lines meet and talk: population coding of somatic sensations

... innocuous cold range (25~28°C), defined in heterologous systems (33, 34). This threshold is lower than that of many human C2 fibers (> 30°C) (18). However, in vivo cold sensitivity of sensory neurons can be modulated by other factors, such as the expression of two potassium channels, TREK1 and TRAAK ...
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... Acetylcholine activates mainly two types of receptors. They are called muscarinic and nicotinic receptors. Muscarine activates only muscarinic receptors whereas nicotine activates only nicotinic receptors; acetylcholine activates both of them. Muscarinic receptors are found on all effector cells tha ...
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An Introduction to the ANS and Higher

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c-Jun Expression in Adult Rat Dorsal Root
c-Jun Expression in Adult Rat Dorsal Root

... which enable these proteins to form hetero- and homodimers, known as transcription factor AP-1, which binds to the activation site in target genes (49). Because dorsal root ganglion (DRG) neurons can be axotomized peripherally or centrally, these neurons provide a useful model for comparing the even ...
Neural Control of Interappendage Phase During Locomotion
Neural Control of Interappendage Phase During Locomotion

... moving at the same low speed, (B) both treadmills moving at the same high speed, and (C) one treadmill moving at the low speed of condition A and the other treadmill moving at the high speed of condition B. In conditions A and B the right and left legs alternate as in normal walking. The results in ...
attention - CMU Graphics
attention - CMU Graphics

... In some trial preferred stimulus and target were same. ○ For example:- We are looking for red color and preferred stimulus of neuron is also red color. ...
optical imaging and control of genetically designated neurons in
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Physiology MCQs
Physiology MCQs

... the clearance is less than the GFR if there is tubular secretion the active transport of Na+ occurs in all portions of the tubule proximal tubular reabsorbate is slightly hypotonic water can leak across tight junctions back into the tubule lumen 30% of the filtered water enters the distal tubule ...
Effects of galanin on wide-dynamic range neuron activity
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... noxious heat and mechanical stimulation in rats with sciatic nerve loose ligation [7]. Our recent study demonstrated that the discharge frequency of the WDR neuron decreased significantly after the administration of galanin in intact rats (unpublished data). The present study demonstrated that the d ...
Nerve cells in the human ciliary muscle: ultrastructural and
Nerve cells in the human ciliary muscle: ultrastructural and

... polypeptide (VIP).19 The physiological role of these peptides for the human ciliary muscle is unclear. In vitro studies indicate that SP is a potent agent to induce contraction of human ciliary muscle strips.20 In addition to the extrinsic innervation deriving from nerve cells outside the eye, intri ...
Discussion and future directions
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... approach the formation of the motor directional maps from the self–organization perspective, the crucial aspect consists of the characterization of the input signals that are available to the training process. From this view, the population coding operating in the motor cortex and the functional con ...
Novel uses of RadioFrequency ablation
Novel uses of RadioFrequency ablation

... lasting inhibition of evoked synaptic activity Pulsed RF (PRF) Brief “pulses” of high-voltage RF-range (<300 kHz) electric current voltage fluctuations in the tissue to be treated ...
DEPARTAMENTO DE CIÊNCIAS DA VIDA
DEPARTAMENTO DE CIÊNCIAS DA VIDA

... identified glycogen synthase kinase 3 beta (GSK3β), heat shock protein 40 (Hsp40) and Rhoassociated, coiled-coil containing protein kinase 2 (RockII) as signals increased after a dorsal root injury that may act as potential regeneration inhibitors. Both GSK3β and RockII were already described in the ...
NervousSystemchapt28
NervousSystemchapt28

... • A stimulus alters the permeability of a portion of the membrane – Allowing ions to pass through and changing the membrane’s voltage ...
Optic Glomeruli and Their Inputs inDrosophilaShare an
Optic Glomeruli and Their Inputs inDrosophilaShare an

... vs c) were made using the Holm step-down procedure (Holm, 1979) to control the overall type I error level. To test the responses of motion stimuli and static patterns, data were analyzed by two-way repeatedmeasures ANOVA with direction/orientation and time (200 ms before vs 200 ms after the onset of ...
Pain Lotion Ingredient List
Pain Lotion Ingredient List

... helps decrease blood pressure by encouraging vasodilation. Vasodilator agents can lead to substantial improvements in neuronal blood flow with corresponding improvements in nerve conduction which can help with diabetic neuropathy. Although Nifedipine’s mode of action in pain management remains uncle ...
The evolution of nervous system centralization
The evolution of nervous system centralization

... Our revised scenario, that the ancestral role of Bmp signalling was to promote sensory over motor neuron fates, rather than a general antineurogenic effect, fits well with the actual distribution of motor and sensory neurons in many invertebrates, where it appears to be the rule rather than the exce ...
Full Text
Full Text

... features as well as a mechanism of injury suggests that these diseases with numerous synonyms may all be part of the same disease spectrum (2,17,18). Marrioti et al. suggested that POLD and HDLS be considered a single entity of adult onset leukodystrophy with neuroaxonal spheroids and pigmented glia ...
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Rheobase



Rheobase is a measure of membrane excitability. In neuroscience, rheobase is the minimal current amplitude of infinite duration (in a practical sense, about 300 milliseconds) that results in the depolarization threshold of the cell membranes being reached, such as an action potential or the contraction of a muscle. In Greek, the root ""rhe"" translates to current or flow, and ""basi"" means bottom or foundation: thus the rheobase is the minimum current that will produce an action potential or muscle contraction.Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). The ease with which a membrane can be stimulated depends on two variables: the strength of the stimulus, and the duration for which the stimulus is applied. These variables are inversely related: as the strength of the applied current increases, the time required to stimulate the membrane decreases (and vice versa) to maintain a constant effect. Mathematically, rheobase is equivalent to half the current that needs to be applied for the duration of chronaxie, which is a strength-duration time constant that corresponds to the duration of time that elicits a response when the nerve is stimulated at twice rheobasic strength.The strength-duration curve was first discovered by G. Weiss in 1901, but it was not until 1909 that Louis Lapicque coined the term ""rheobase"". Many studies are being conducted in relation to rheobase values and the dynamic changes throughout maturation and between different nerve fibers. In the past strength-duration curves and rheobase determinations were used to assess nerve injury; today, they play a role in clinical identification of many neurological pathologies, including as Diabetic neuropathy, CIDP, Machado-Joseph Disease, and ALS.
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