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Chapter 8 The Nervous System
Chapter 8 The Nervous System

... Dendrites and cell bodies of sympathetic preganglionic neurons are located in the gray matter of the thoracic and upper lumbar segments of the spinal cord Axons leave the spinal cord in the anterior roots of spinal nerves, extend to sympathetic or collateral ganglia, and synapse with several postgan ...
Activities of the Primary and Supplementary Motor Areas Increase in
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... and the other did not (i.e., isometric). All the tasks were performed with the subject’s right hand. For the sake of analysis, each trial was divided into three different phases: “premotor”, “motor”, and “postmotor” for all the tasks. In the muscle relaxation mode under movement condition (R_mv), th ...
Autonomic Nervous System
Autonomic Nervous System

... cord to one or more muscle fibers (figure 18.1). The impulses conducted by these motor neurons stimulate skeletal muscle fibers, causing them to contract. Contraction continues until neuron impulses cease to stimulate the muscle fiber. By contrast, the ANS uses a pathway that includes a two-neuron c ...
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PERSPECTIVES

... between the observed action they responded to and the executed action that triggered their discharge. It therefore seems that there are three interconnected areas in the monkey brain that contain neurons that are responsive to biological movements. These areas differ in their motor properties. In F5 ...
The Torah of Life - The Torah Science Foundation
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... during the day, such as walking, working, playing, or even thinking, requires energy, and food is the substance which fuels our daily activities. A major component of food is the chemical glucose. We learned in an earlier chapter that cells convert glucose and other molecules into ATP, and ATP is th ...
Y.I. Molkov, Baroreflex models, Encyclopedia of Computational
Y.I. Molkov, Baroreflex models, Encyclopedia of Computational

... where n is the firing rate of the baroreceptor, Pc is the carotid pressure, M is the maximal firing rate, t is the adaptation time constant, k is a weighting constant, and N denotes the threshold. Instantaneous rate of change of the firing rate is proportional to the time derivative of carotid press ...
Synaptic Transmission 1
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The Nervous System
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BIO 210 Course Outline
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... 1. Define twitch and describe its characteristics in different muscles. 2. Distinguish between a twitch and the effects generated by repeated stimulation (e.g., treppe, wave summation, tetanus). G. Describe motor units and their role in maintaining tension during muscle contraction, i.e., recruitmen ...
Excitatory Postsynaptic Potentials Trigger a Plateau Potential in Rat
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... Wichmann et al. 1994b). These observations indicate the importance of controlling outputs of the basal ganglia by STN neurons. It is therefore crucial to know how the activity of STN neurons is regulated for understanding basal ganglia function in motor control. The activity of a neuron is determine ...
Unit 7 Nervous System - Lemon Bay High School
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Molecular mechanisms of growth cone guidance
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... The classical guidance cues for growing axons were thought to be attractive cell surface molecules. Evidence from in vitro studies suggested that growth cone guidance could be explained, at least in part, by differential adhesion (see, for example, Letourneau 1975). However, after identification of ...
THE METABOLISM OF GAMMA AMINOBUTYRIC
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... The most obvious is the variation in geometrical shape . Neurons can also differ in the chemical transmitter compound which they secrete . There are more subtle differences which are shown up by the ability of neurons to recognize and contact other cells specifically . This heterogeneity will depend ...
Targeting of Rough Endoplasmic Reticulum Membrane Proteins and
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... ribophorins I and II (components of the oligosaccharyl transferase) were found to be enriched in the RER (Kreibich et al., 1978), as was a subunit of signal peptidase and TRAP␣ (SSR␣; Vogel et al., 1990) and Sec61␣ (Meyer et al., 2000). The common feature of these proteins is that they are involved ...
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Skeletal Muscle Mechanics
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... frequency to increase the tension in a skeletal muscle fiber beyond that produced by a single action potential.  2. Tetany - Maximal skeletal muscle contraction produced by a series of high frequency action potentials. ...
Depolarization stimulates lamellipodia formation and
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... stained cells were quickly pelleted for 10 s in an eppendorf centrifuge and washed three times by resuspension in 1 ml GCM containing 0.2% bovine serum albumin ŽBSA. and centrifugation. After the last centrifugation step, the cells were resuspended in 1 ml GCM and counted. The stained cells were dil ...
Dorsal Column Nuclei Neurons Recorded in a Brain Stem–Spinal
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... different and all neurons were considered together. Dorsal root stimulation elicited excitatory postsynaptic potentials (EPSPs) in all neurons with a very low variability in onset latency and an ability to follow 100-Hz stimulation, indicating that they were mediated by activation of a monosynaptic ...
ppt - UC Davis Imaging Research Center
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... operationalized in a variety of ways across studies  No studies have been run assessing whether behavioral effects vary according to the type of switch required  Only recently have attempts been made to dissociate neural activity in regard to different types of shifts (Wager, et al., 2005).  We f ...
LYRICA (pregabalin) eLearning System
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... pain is sometimes perceived at a location remote from the actual site of injury, the pain is often out of proportion to the stimulus, and the duration of the pain may be prolonged. Two of the key types of neuropathic pain are painful diabetic peripheral neuropathy (pDPN) and postherpetic neuralgia ( ...
Nervous System
Nervous System

...  Impulses travel faster when fibers have a myelin sheath ...
BACOFUN_2016 Meeting Booklet - Barrel Cortex Function 2016
BACOFUN_2016 Meeting Booklet - Barrel Cortex Function 2016

... Dense Statistical Connectome of Rat Barrel Cortex Daniel Udvary, Robert Egger, Vincent J. Dercksen, and Marcel Oberlaender Synaptic connectivity is one important constrain for cortical signal flow and function. Consequently, a complete synaptic connectivity map (i.e., connectome) of a cortical area ...
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Rheobase



Rheobase is a measure of membrane excitability. In neuroscience, rheobase is the minimal current amplitude of infinite duration (in a practical sense, about 300 milliseconds) that results in the depolarization threshold of the cell membranes being reached, such as an action potential or the contraction of a muscle. In Greek, the root ""rhe"" translates to current or flow, and ""basi"" means bottom or foundation: thus the rheobase is the minimum current that will produce an action potential or muscle contraction.Rheobase can be best understood in the context of the strength-duration relationship (Fig. 1). The ease with which a membrane can be stimulated depends on two variables: the strength of the stimulus, and the duration for which the stimulus is applied. These variables are inversely related: as the strength of the applied current increases, the time required to stimulate the membrane decreases (and vice versa) to maintain a constant effect. Mathematically, rheobase is equivalent to half the current that needs to be applied for the duration of chronaxie, which is a strength-duration time constant that corresponds to the duration of time that elicits a response when the nerve is stimulated at twice rheobasic strength.The strength-duration curve was first discovered by G. Weiss in 1901, but it was not until 1909 that Louis Lapicque coined the term ""rheobase"". Many studies are being conducted in relation to rheobase values and the dynamic changes throughout maturation and between different nerve fibers. In the past strength-duration curves and rheobase determinations were used to assess nerve injury; today, they play a role in clinical identification of many neurological pathologies, including as Diabetic neuropathy, CIDP, Machado-Joseph Disease, and ALS.
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