Simulating in vivo-like Synaptic Input Patterns in Multicompartmental
... combined synaptic conductance would generate 3 nA of synaptic current—which is a lot of current. Although this example exaggerates the actual effect of in vivo synaptic conductances by ignoring their spatial distribution, it illustrates the point that for most types of neurons, the total membrane co ...
... combined synaptic conductance would generate 3 nA of synaptic current—which is a lot of current. Although this example exaggerates the actual effect of in vivo synaptic conductances by ignoring their spatial distribution, it illustrates the point that for most types of neurons, the total membrane co ...
Structure of the Transmembrane Cysteine Residues in
... The amide I and amide II vibrational modes are sensitive to and diagnostic of secondary structure in proteins (Braiman & Rothschild, 1988). Figure 1 presents the amide I-II region of the phospholamban peptides that have been reconstituted into DMPC bilayers. The amide I and amide II bands are center ...
... The amide I and amide II vibrational modes are sensitive to and diagnostic of secondary structure in proteins (Braiman & Rothschild, 1988). Figure 1 presents the amide I-II region of the phospholamban peptides that have been reconstituted into DMPC bilayers. The amide I and amide II bands are center ...
Transcripts/2_23 2
... medial vestibular nucleus to the abducens takes care of the appropriate activity for the vestibule-ocular reflex in the lateral rectus on both sides. And then the internuclear pathway to the medial rectus motor neurons on the left and the right take care of the appropriate activity for the left and ...
... medial vestibular nucleus to the abducens takes care of the appropriate activity for the vestibule-ocular reflex in the lateral rectus on both sides. And then the internuclear pathway to the medial rectus motor neurons on the left and the right take care of the appropriate activity for the left and ...
Neuronal morphology in the African elephant (Loxodonta africana
... Briefly, selected neurons were required to be relatively isolated and unobscured, to appear fully impregnated with a soma roughly centered within the 120 lm-thick section, and to have as complete dendritic arbors as possible. In order to create a relatively homogeneous cell population for superficia ...
... Briefly, selected neurons were required to be relatively isolated and unobscured, to appear fully impregnated with a soma roughly centered within the 120 lm-thick section, and to have as complete dendritic arbors as possible. In order to create a relatively homogeneous cell population for superficia ...
Gustatory Processing in Drosophila Higher Brain Centers By
... downstream targets of PKA are necessary for STM, whereas CREB is essential for LTM alone (Yin et al., 1994) and has been implicated in the de novo transcription of proteins involved in the process. A gene called amnesiac (amn) is necessary for the development of MTM. Amnesiac mutants were identifie ...
... downstream targets of PKA are necessary for STM, whereas CREB is essential for LTM alone (Yin et al., 1994) and has been implicated in the de novo transcription of proteins involved in the process. A gene called amnesiac (amn) is necessary for the development of MTM. Amnesiac mutants were identifie ...
final scientific program
... One of the fundamental problems in neuroscience today is to understand how the activation of large populations of neurons gives rise to the higher order functions of the brain including learning, memory, cognition, perception, action and ultimately conscious awareness. Electrophysiological recording ...
... One of the fundamental problems in neuroscience today is to understand how the activation of large populations of neurons gives rise to the higher order functions of the brain including learning, memory, cognition, perception, action and ultimately conscious awareness. Electrophysiological recording ...
Calcium Binding Protein-Like lmmunoreactivity Labels the Terminal
... Bristol Laboratories) and were kept warm with a heating pad throughout the injection procedure. The micropipette was targeted stereotaxically and lowered into NL with a remote-controlled, stepping motor-coupled microdrive. Evoked potentials or “neurophonic” responses (see Sullivan and Konishi, 1986) ...
... Bristol Laboratories) and were kept warm with a heating pad throughout the injection procedure. The micropipette was targeted stereotaxically and lowered into NL with a remote-controlled, stepping motor-coupled microdrive. Evoked potentials or “neurophonic” responses (see Sullivan and Konishi, 1986) ...
Chapter 17 Intrinsic Optical Signal Imaging of Normal and Abnormal
... however, has only been investigated using autoradiography (1, 55, 75), SPECT (78), and fMRI (3, 41, 53), which lack high temporal resolution. Using ORIS at 546 nm, we have shown that as early as 100 ms after an epileptiform event, one can record a focal increase in CBV that is as highly localized as ...
... however, has only been investigated using autoradiography (1, 55, 75), SPECT (78), and fMRI (3, 41, 53), which lack high temporal resolution. Using ORIS at 546 nm, we have shown that as early as 100 ms after an epileptiform event, one can record a focal increase in CBV that is as highly localized as ...
The Basal Ganglia
... • Inputs. Though the striatum projects to dopamine neurons, they respond mostly with longer latencies and without homogeneous and salience-specific characteristics. Short latency, complex excitatory input may arrive from the reticular formation, particularly the nucleus pedunculopontinus. • Contradi ...
... • Inputs. Though the striatum projects to dopamine neurons, they respond mostly with longer latencies and without homogeneous and salience-specific characteristics. Short latency, complex excitatory input may arrive from the reticular formation, particularly the nucleus pedunculopontinus. • Contradi ...
Sounds of Silence BU scientists are helping a paralyzed man utter his
... Jonathan Brumberg, a postdoctoral research associate in Guenther’s lab, are working to help Ramsey and others who have lost the ability to speak because of stroke or disease. Guenther has been developing a neural model of speech for more than two decades, one that he and Brumberg used as a Rosetta S ...
... Jonathan Brumberg, a postdoctoral research associate in Guenther’s lab, are working to help Ramsey and others who have lost the ability to speak because of stroke or disease. Guenther has been developing a neural model of speech for more than two decades, one that he and Brumberg used as a Rosetta S ...
Co-activation of VTA DA and GABA neurons mediates nicotine
... Smoking is the most important preventable cause of mortality and morbidity worldwide. This nicotine addiction is mediated through the nicotinic acetylcholine receptor (nAChR), expressed on most neurons, and also many other organs in the body. Even within the ventral tegmental area (VTA), the key bra ...
... Smoking is the most important preventable cause of mortality and morbidity worldwide. This nicotine addiction is mediated through the nicotinic acetylcholine receptor (nAChR), expressed on most neurons, and also many other organs in the body. Even within the ventral tegmental area (VTA), the key bra ...
NAlab13_LimbicSystem..
... The medial surfaces of the telencephalon and diencephalon are illustrated in the top panel. Below is a “cut-away” view of diencephalic and telencephalic nuclei and tracts. Use these two illustrations to familiarize yourself with the key structures of the limbic system. On the medial brain surface, i ...
... The medial surfaces of the telencephalon and diencephalon are illustrated in the top panel. Below is a “cut-away” view of diencephalic and telencephalic nuclei and tracts. Use these two illustrations to familiarize yourself with the key structures of the limbic system. On the medial brain surface, i ...
Limbic System
... The medial surfaces of the telencephalon and diencephalon are illustrated in the top panel. Below is a “cut-away” view of diencephalic and telencephalic nuclei and tracts. Use these two illustrations to familiarize yourself with the key structures of the limbic system. On the medial brain surface, i ...
... The medial surfaces of the telencephalon and diencephalon are illustrated in the top panel. Below is a “cut-away” view of diencephalic and telencephalic nuclei and tracts. Use these two illustrations to familiarize yourself with the key structures of the limbic system. On the medial brain surface, i ...
The Red Nucleus: Past, Present, and Future
... fins of their aquatic predecessors became objects of locomotion in the air or on the ground [1]. Locomotion using limbs led to a dedicated descending pathway by which the central nervous system (CNS) could initiate movement. Examination of the red nucleus’ role in limb movement requires an understan ...
... fins of their aquatic predecessors became objects of locomotion in the air or on the ground [1]. Locomotion using limbs led to a dedicated descending pathway by which the central nervous system (CNS) could initiate movement. Examination of the red nucleus’ role in limb movement requires an understan ...
Cellular mechanisms underlying network synchrony in the medial
... Encoding interference problem Spike ...
... Encoding interference problem Spike ...
video slide - Plattsburgh State Faculty and Research Web Sites
... • The net flow of K+ ions will continue and the negative charge will increase until the difference in charge between the inside and outside of the cell (which attracts K+ ions back into the cell) balances the effect of the concentration gradient for K+, which is causing K+ ions to flow out. • If it ...
... • The net flow of K+ ions will continue and the negative charge will increase until the difference in charge between the inside and outside of the cell (which attracts K+ ions back into the cell) balances the effect of the concentration gradient for K+, which is causing K+ ions to flow out. • If it ...
The Complicated Equation of Smell, Flavor, and Taste
... The olfactory system in vertebrates has a unique embryology. It forms from 1) paired placodes made of non-neural epithelium that have the capacity to give rise to sensory neurons and supporting cells in the olfactory epithelium, and 2) neural crest cells that give origin to the structural elements o ...
... The olfactory system in vertebrates has a unique embryology. It forms from 1) paired placodes made of non-neural epithelium that have the capacity to give rise to sensory neurons and supporting cells in the olfactory epithelium, and 2) neural crest cells that give origin to the structural elements o ...
Maruska et al. 2007
... among closely related species. Thus to understand the evolution and proximate control of social behavior, it is necessary to determine neuroanatomical co-variation by sex and season among multiple neurochemical groups within a single species. Wild fish populations show distinct annual reproductive c ...
... among closely related species. Thus to understand the evolution and proximate control of social behavior, it is necessary to determine neuroanatomical co-variation by sex and season among multiple neurochemical groups within a single species. Wild fish populations show distinct annual reproductive c ...
SENSE AND THE SINGLE NEURON: Probing the Physiology of
... firing to the intensity of the flash. In order to decide whether the neuron had signaled the presence of the stimulus on any single trial, they required that the neuron fire N action potentials on that trial, where N is greater than or equal to a criterion number, M. For each stimulus level, the pro ...
... firing to the intensity of the flash. In order to decide whether the neuron had signaled the presence of the stimulus on any single trial, they required that the neuron fire N action potentials on that trial, where N is greater than or equal to a criterion number, M. For each stimulus level, the pro ...
Building silicon nervous systems with dendritic tree neuromorphs
... Essential to an understanding of a brain is an understanding of the signaling taking place within it [Koch, 1997]. Questions as to the nature of neural codes are being tackled by collecting electrophysiological data and analyzing trains of action potentials or spikes for the information that they co ...
... Essential to an understanding of a brain is an understanding of the signaling taking place within it [Koch, 1997]. Questions as to the nature of neural codes are being tackled by collecting electrophysiological data and analyzing trains of action potentials or spikes for the information that they co ...
Channelrhodopsin
Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.