Solvent Accessibility Prediction in proteins
... • Accessible surface area (ASA) determines stability of proteins, as hydrophobic transfer energy is directly a measure of residue-wise solvent accessible surface. • Buried residues reside in the core of the protein and hence crucial to stability, even if they may not be active sites. • A protein may ...
... • Accessible surface area (ASA) determines stability of proteins, as hydrophobic transfer energy is directly a measure of residue-wise solvent accessible surface. • Buried residues reside in the core of the protein and hence crucial to stability, even if they may not be active sites. • A protein may ...
Introduction - Bowling Green State University
... since arousal function can be better explained by large-scale energetic states of the brain. This approach, especially developed in Parkinson disease studies, showed that blocking the amount of cortical descending activity into basal ganglia (Siggins 1978, Dray 1980, Yim & Mogenson 1982, Brown & Arb ...
... since arousal function can be better explained by large-scale energetic states of the brain. This approach, especially developed in Parkinson disease studies, showed that blocking the amount of cortical descending activity into basal ganglia (Siggins 1978, Dray 1980, Yim & Mogenson 1982, Brown & Arb ...
Why Are Olfactory Systems of Different Animals So Similar?
... groups, and their dendrites project to a dense olfactory epithelium at the tip of the tentacle. The axons of most of these cells project a short distance into regions associated with the tentacle ganglion [Chase and Tolloczko, 1993]. In Caenorhabditis elegans, olfactory receptor neurons are found i ...
... groups, and their dendrites project to a dense olfactory epithelium at the tip of the tentacle. The axons of most of these cells project a short distance into regions associated with the tentacle ganglion [Chase and Tolloczko, 1993]. In Caenorhabditis elegans, olfactory receptor neurons are found i ...
106th Annual Meeting of the German Zoological Society Abstracts
... human speech and for bird song learning. In vitro, transcriptional activity of FoxP2 requires dimerization with itself or with paralogues FoxP1 and FoxP4. To investigate the potential relevance of synergies between the different FoxP proteins, we studied neural co-expression, dimerization and compar ...
... human speech and for bird song learning. In vitro, transcriptional activity of FoxP2 requires dimerization with itself or with paralogues FoxP1 and FoxP4. To investigate the potential relevance of synergies between the different FoxP proteins, we studied neural co-expression, dimerization and compar ...
Experience-dependent corticofugal adjustment
... observed in the central nucleus of the IC by Yan and Suga (11), we delivered ASr in the same way as in that research. The BFs of single or multiple IC neurons were measured before and after 30-min delivery of ASr. (Step 2) To examine whether auditory experience based on associative learning evokes a ...
... observed in the central nucleus of the IC by Yan and Suga (11), we delivered ASr in the same way as in that research. The BFs of single or multiple IC neurons were measured before and after 30-min delivery of ASr. (Step 2) To examine whether auditory experience based on associative learning evokes a ...
Caudal Topographic Nucleus Isthmi and the Rostra1
... neurons labeled in Imr, nucleus lentiformis mesencephali, or profundus mesencephali rostralis (PMr). The axons of neurons in those nuclei were reconstructed from serial sections and found to branch widely, sparsely innervating large areas of the tectum. Fourth, the dense thickets are not terminals o ...
... neurons labeled in Imr, nucleus lentiformis mesencephali, or profundus mesencephali rostralis (PMr). The axons of neurons in those nuclei were reconstructed from serial sections and found to branch widely, sparsely innervating large areas of the tectum. Fourth, the dense thickets are not terminals o ...
Introduction to Data Communication Networks - DSpace
... Anatomy of the Nervous systems Neuron cells are the information-processing units of the brain ...
... Anatomy of the Nervous systems Neuron cells are the information-processing units of the brain ...
Role of the basal ganglia in conditional associative learning
... The arbitrary mapping of sensory information onto action forms an important element of the intelligent behavior of primates (also called conditional associative learning). The cortico-basal ganglia-thalamo-cortical loops are thought to play a key role in such behavior. The present research was under ...
... The arbitrary mapping of sensory information onto action forms an important element of the intelligent behavior of primates (also called conditional associative learning). The cortico-basal ganglia-thalamo-cortical loops are thought to play a key role in such behavior. The present research was under ...
Projections from the spinal trigeminal nucleus to the cochlear
... meaning of a sound depends on more than its physical characteristics. In the dorsal cochlear nucleus (DCN) of the cat, the response properties of projection neurons (e.g., pyramidal and giant cells) are modulated by manipulating the pinna or electrically stimulating the nerve carrying proprioceptive ...
... meaning of a sound depends on more than its physical characteristics. In the dorsal cochlear nucleus (DCN) of the cat, the response properties of projection neurons (e.g., pyramidal and giant cells) are modulated by manipulating the pinna or electrically stimulating the nerve carrying proprioceptive ...
Review Spectrin and calpain
... both ubiquitous and tissue-specific isoforms in higher organisms. Homologues of calpain catalytic subunits are also present in other groups of organisms, including invertebrates, plants and fungi. The two ubiquitously expressed isoforms of the calpain superfamily, m-calpain and mcalpain, are so far ...
... both ubiquitous and tissue-specific isoforms in higher organisms. Homologues of calpain catalytic subunits are also present in other groups of organisms, including invertebrates, plants and fungi. The two ubiquitously expressed isoforms of the calpain superfamily, m-calpain and mcalpain, are so far ...
- CUNY Academic Works
... amygdala (AMG) and prefrontal cortex (PFC). These forebrain regions will be referred to as the DA terminal regions. The neural mechanisms underlying this type of rewardrelated learning in this system are not fully understood, particularly how neutral stimuli become CSs. One possibility is that a con ...
... amygdala (AMG) and prefrontal cortex (PFC). These forebrain regions will be referred to as the DA terminal regions. The neural mechanisms underlying this type of rewardrelated learning in this system are not fully understood, particularly how neutral stimuli become CSs. One possibility is that a con ...
Motor Control - Reza Shadmehr
... mossy fibers originating in the basilar pontine nuclei. In addition, the cerebellum receives mossy fiber input from the red nucleus via the lateral reticular nucleus (which also has major spinal inputs) and from other sources. Mossy fibers terminate on the output nuclei of the cerebellum (the deep cere ...
... mossy fibers originating in the basilar pontine nuclei. In addition, the cerebellum receives mossy fiber input from the red nucleus via the lateral reticular nucleus (which also has major spinal inputs) and from other sources. Mossy fibers terminate on the output nuclei of the cerebellum (the deep cere ...
Smelling on the fly: sensory cues and strategies for olfactory
... Smelling on the fly: sensory cues and strategies for olfactory navigation in Drosophila Quentin Gaudry1, Katherine I Nagel1 and Rachel I Wilson Navigating toward (or away from) a remote odor source is a challenging problem that requires integrating olfactory information with visual and mechanosensor ...
... Smelling on the fly: sensory cues and strategies for olfactory navigation in Drosophila Quentin Gaudry1, Katherine I Nagel1 and Rachel I Wilson Navigating toward (or away from) a remote odor source is a challenging problem that requires integrating olfactory information with visual and mechanosensor ...
Section and Senior Editor - HAL
... From both classical and recent investigations, there is now little doubt that the posterior hypothalamus plays a key role in the maintenance of cortical activation and wakefulness (W). Indeed, since von Economo (1926) initially identified a lethargy in patients suffering from inflammatory lesions wi ...
... From both classical and recent investigations, there is now little doubt that the posterior hypothalamus plays a key role in the maintenance of cortical activation and wakefulness (W). Indeed, since von Economo (1926) initially identified a lethargy in patients suffering from inflammatory lesions wi ...
... modest reduction in PKB activity compared with the wild type littermates, and prone to diabetes. The importance of this pathway in tumourogenesis has been highlighted by introducing the PDK1 PH domain knock-in mutation into cancer-prone PTEN+/- mice, which resulted in the delayed tumour onset, sugge ...
Citation As Published Publisher Version Accessed
... ‘motif’. The individual syllables last roughly 100ms and are reproduced in highly stereotyped fashion across song renditions (Figure 1A). The neural circuitry underlying adult song production is well identified and exists in all songbird species that have been studied (Wild, 1997). The forebrain nuc ...
... ‘motif’. The individual syllables last roughly 100ms and are reproduced in highly stereotyped fashion across song renditions (Figure 1A). The neural circuitry underlying adult song production is well identified and exists in all songbird species that have been studied (Wild, 1997). The forebrain nuc ...
Control of Gonadotropin Secretion by Follicle
... decreased. On the basis of our recent studies with biotinylated lGnRH-III, we believe that ultimately a specific receptor for this peptide will be found in the pituitary; additionally, it is in all probability the FSH-releasing factor. lGnRH-III binds to the three GnRH receptors discovered in the bu ...
... decreased. On the basis of our recent studies with biotinylated lGnRH-III, we believe that ultimately a specific receptor for this peptide will be found in the pituitary; additionally, it is in all probability the FSH-releasing factor. lGnRH-III binds to the three GnRH receptors discovered in the bu ...
Modelling Neuronal Mechanisms of the Processing of Tones and System
... The scientific study of the perception of sequences of alternating auditory stimuli has a long tradition. Already more than half a century ago, researchers started mapping the dependence of what humans perceive when listening to such sequences on the basic experimental parameters of spectral distanc ...
... The scientific study of the perception of sequences of alternating auditory stimuli has a long tradition. Already more than half a century ago, researchers started mapping the dependence of what humans perceive when listening to such sequences on the basic experimental parameters of spectral distanc ...
Fluctuations in Perceptual Decisions Panagiota Theodoni
... word in science. How could we study subjectivity objectively? This was the main obstacle, since objectivation is a “pillar” of science, although debatable (Schrödinger 1967). The bridge to this gap came, in the second half of 19th century, from Franz Brentano who suggested three different forms of c ...
... word in science. How could we study subjectivity objectively? This was the main obstacle, since objectivation is a “pillar” of science, although debatable (Schrödinger 1967). The bridge to this gap came, in the second half of 19th century, from Franz Brentano who suggested three different forms of c ...
Condition interference in rats performing a choice task with switched
... of 30 kHz. We then applied an offline digital high-pass filter of 200 Hz (Matlab; The Mathworks). When the signal became below or above its root mean square (RMS) times 5.5, the signal was defined as spike activity (Torab et al., 2011). Offline spike sorting was conducted using Spike 2 (CED), with w ...
... of 30 kHz. We then applied an offline digital high-pass filter of 200 Hz (Matlab; The Mathworks). When the signal became below or above its root mean square (RMS) times 5.5, the signal was defined as spike activity (Torab et al., 2011). Offline spike sorting was conducted using Spike 2 (CED), with w ...
Channelrhodopsin
Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.