Cauda Equina Syndrome and Nitric Oxide Synthase
... with Permount. Negative controls were applied by omitting the primary antibody. Nitric oxide synthase radioassay The radioassay detection of cNOS activity was determined by the conversion of [3H]-arginine to [3H]citrulline according to the method of Bredt and Snyder (1990) with a slight modification ...
... with Permount. Negative controls were applied by omitting the primary antibody. Nitric oxide synthase radioassay The radioassay detection of cNOS activity was determined by the conversion of [3H]-arginine to [3H]citrulline according to the method of Bredt and Snyder (1990) with a slight modification ...
Neural Correlates of Vibrissa Resonance: Band
... (A) Left: an example of a trigeminal ganglion (NV) single unit driven by B2 vibrissa stimulation at multiple frequencies. Spiking rate (top) shows a strong relation to vibrissa motion amplitude (middle). Vertical bars indicate the best frequency (BF, black), the frequency that drove peak neural acti ...
... (A) Left: an example of a trigeminal ganglion (NV) single unit driven by B2 vibrissa stimulation at multiple frequencies. Spiking rate (top) shows a strong relation to vibrissa motion amplitude (middle). Vertical bars indicate the best frequency (BF, black), the frequency that drove peak neural acti ...
Here - Institute of Cognitive Neuroscience
... an understanding would serve to bridge between the neurophysiological and behavioral levels of description via systems neuroscience, allowing for the reinforcement of convergent information and the resolution of questions at one level of description by inferences drawn from another. Moreover, a theo ...
... an understanding would serve to bridge between the neurophysiological and behavioral levels of description via systems neuroscience, allowing for the reinforcement of convergent information and the resolution of questions at one level of description by inferences drawn from another. Moreover, a theo ...
TESIS DOCTORAL Regulación de la plasticidad y de la capacidad
... regulation of gene expression by mRNA destabilization and/or translational repression. Many approaches have been used to clarify the role of individual miRNAs but, recently, a new hypothesis about their mechanism of action proposes the importance to consider miRNA system as a whole. The ablation of ...
... regulation of gene expression by mRNA destabilization and/or translational repression. Many approaches have been used to clarify the role of individual miRNAs but, recently, a new hypothesis about their mechanism of action proposes the importance to consider miRNA system as a whole. The ablation of ...
Article - Leslie Vosshall - The Rockefeller University
... V glomerulus volume increases were highly significant even when all measurements from all manipulations in Figures 1B and 1C and Figure 2B were pooled and analyzed (p < 0.001; see Figure S1 available online), demonstrating that activity-dependent volume increases were considerably larger than sample ...
... V glomerulus volume increases were highly significant even when all measurements from all manipulations in Figures 1B and 1C and Figure 2B were pooled and analyzed (p < 0.001; see Figure S1 available online), demonstrating that activity-dependent volume increases were considerably larger than sample ...
Basal Ganglia - Adaptive Behaviour Research Group
... The principle input components of the basal ganglia are the striatum and the STN. Afferent connections to both of these structures originate from virtually the entire brain including, cerebral cortex, many parts of the brainstem (via the thalamus), and the limbic system. Input connections provide ph ...
... The principle input components of the basal ganglia are the striatum and the STN. Afferent connections to both of these structures originate from virtually the entire brain including, cerebral cortex, many parts of the brainstem (via the thalamus), and the limbic system. Input connections provide ph ...
Outputs of Radula Mechanoafferent Neurons in Aplysia are
... the modulation produced by B4/5, whereas excitatory and/or electrical synapses were involved in the other instances. The data indicate that modulation is due to block of action potential invasion into synaptic release regions or to alterations of transmitter release as a function of the presynaptic ...
... the modulation produced by B4/5, whereas excitatory and/or electrical synapses were involved in the other instances. The data indicate that modulation is due to block of action potential invasion into synaptic release regions or to alterations of transmitter release as a function of the presynaptic ...
Olfactory tract transection in neonatal rats: Evidence for Mitral cell
... Received 14 May 2012; revised 9 August 2012 Central Nervous System (CNS) regeneration and repair mechanism are two important aspects of functional recovery in the adult central nervous system following brain and spinal cord injury. Following olfactory tract transection in neonatal rats, functional c ...
... Received 14 May 2012; revised 9 August 2012 Central Nervous System (CNS) regeneration and repair mechanism are two important aspects of functional recovery in the adult central nervous system following brain and spinal cord injury. Following olfactory tract transection in neonatal rats, functional c ...
Balanced Excitatory and Inhibitory Inputs to Cortical Neurons
... Koch, 1993; Holt et al., 1996; Shadlen and Newsome, 1998), which is often represented as Poisson-like spike trains. Background synaptic input with balanced excitation and inhibition has been suggested to generate the irregular firing, although other mechanisms are also possible (Reyes, 2003; Durstew ...
... Koch, 1993; Holt et al., 1996; Shadlen and Newsome, 1998), which is often represented as Poisson-like spike trains. Background synaptic input with balanced excitation and inhibition has been suggested to generate the irregular firing, although other mechanisms are also possible (Reyes, 2003; Durstew ...
working draft - DAVID KAPLAN | Macquarie University
... For further discussion of the distinction between epistemological and ontological construals of reductionism, and the importance of the former over the latter in scientific contexts, see Ayala (1968) Hoyningen-Huene (1989). Although these authors are explicitly concerned with reductionism in biology ...
... For further discussion of the distinction between epistemological and ontological construals of reductionism, and the importance of the former over the latter in scientific contexts, see Ayala (1968) Hoyningen-Huene (1989). Although these authors are explicitly concerned with reductionism in biology ...
Cortical Connectivity Suggests a Role in Limb
... Figure 3. Location of injection site in lateral PE (case 1) and cortical distribution of retrograde-labeled cells. Sagittal sections (A–F ) were taken at the levels indicated on the brain silhouette. Bottom right, Two-dimensional reconstruction illustrating the distribution and density of labeled ce ...
... Figure 3. Location of injection site in lateral PE (case 1) and cortical distribution of retrograde-labeled cells. Sagittal sections (A–F ) were taken at the levels indicated on the brain silhouette. Bottom right, Two-dimensional reconstruction illustrating the distribution and density of labeled ce ...
Insulin Treatment Prevents Neuroinflammation and Neuronal Injury
... The precise determinants of HAND remain unclear, although host factors (age, genetic background, comorbidities), neuroinflammatory processes (inflammasome activation, cytokine production), and viral properties (replicative capacity, neural cell tropism and virus-encoded neurotoxic proteins) have bee ...
... The precise determinants of HAND remain unclear, although host factors (age, genetic background, comorbidities), neuroinflammatory processes (inflammasome activation, cytokine production), and viral properties (replicative capacity, neural cell tropism and virus-encoded neurotoxic proteins) have bee ...
High baseline activity in inferior temporal cortex
... activity was considered noise. However, these human studies do not provide any direct information about the correlation of the baseline activity of single neurons and the behavior. Furthermore, it is not clear how the “oscillation” and the “level” of the neural baseline activity are related to each ...
... activity was considered noise. However, these human studies do not provide any direct information about the correlation of the baseline activity of single neurons and the behavior. Furthermore, it is not clear how the “oscillation” and the “level” of the neural baseline activity are related to each ...
Huffman PowerPoint Slides
... Psychology in Action, Fifth Edition by Karen Huffman, Mark Vernoy, and Judith Vernoy © 2000 John Wiley & Sons, Inc. Huffman/Vernoy/Vernoy: Psychology in Action 5e ...
... Psychology in Action, Fifth Edition by Karen Huffman, Mark Vernoy, and Judith Vernoy © 2000 John Wiley & Sons, Inc. Huffman/Vernoy/Vernoy: Psychology in Action 5e ...
Chapter 2 - Monsignor Farrell High School
... into the brain through which an electrical current is sent that destroys the brain cells at the tip of the wire – electrical stimulation of the brain (ESB): milder electrical current that causes neurons to react as if they had received a message – human brain damage Psychology, Fourth Edition, AP Ed ...
... into the brain through which an electrical current is sent that destroys the brain cells at the tip of the wire – electrical stimulation of the brain (ESB): milder electrical current that causes neurons to react as if they had received a message – human brain damage Psychology, Fourth Edition, AP Ed ...
Functional Heterogeneity in the Bed Nucleus of the Stria Terminalis
... case of the corticotropin releasing factor (CRF) cells located in the oval nucleus (Sakanaka et al., 1987; Phelix and Paull, 1990), which also express a fast inwardly rectifying K ⫹ conductance (known as Type III cells; Fig. 3C) (Dabrowska et al., 2013a; but see Silberman et al., 2013). It should be ...
... case of the corticotropin releasing factor (CRF) cells located in the oval nucleus (Sakanaka et al., 1987; Phelix and Paull, 1990), which also express a fast inwardly rectifying K ⫹ conductance (known as Type III cells; Fig. 3C) (Dabrowska et al., 2013a; but see Silberman et al., 2013). It should be ...
full text - TReAD Lab
... received less scholarly attention than its neighbors, its function has recently become the subject of great interest. In particular, clinical scientists have become interested in its contributions to the control of motivated behavior and clinical pathologies such as Parkinson's disease (PD) and obse ...
... received less scholarly attention than its neighbors, its function has recently become the subject of great interest. In particular, clinical scientists have become interested in its contributions to the control of motivated behavior and clinical pathologies such as Parkinson's disease (PD) and obse ...
Imaging development and plasticity in the mouse visual system
... important role in the development of the brain. Sensory experiences continue to exert a strong influence on the functional connectivity of neuronal circuits, especially in the cerebral cortex, allowing for learning and adaptation to an ever changing environment. The visual system provides a convenie ...
... important role in the development of the brain. Sensory experiences continue to exert a strong influence on the functional connectivity of neuronal circuits, especially in the cerebral cortex, allowing for learning and adaptation to an ever changing environment. The visual system provides a convenie ...
Synaptic plasticity: taming the beast
... a response should grow stronger, but over time Hebbian plasticity has come to mean any long-lasting form of synaptic modification (strengthening or weakening) that is synapse specific and depends on correlations between pre- and postsynaptic firing. By acting independently at each synapse, Hebbian p ...
... a response should grow stronger, but over time Hebbian plasticity has come to mean any long-lasting form of synaptic modification (strengthening or weakening) that is synapse specific and depends on correlations between pre- and postsynaptic firing. By acting independently at each synapse, Hebbian p ...
Connexin-based channels contribute to metabolic pathways in the
... through Glut1 (also known as SLC2A1) and MCT1, respectively (Hirrlinger and Nave, 2014; Morrison et al., 2013; Rinholm et al., 2011; Saab et al., 2013). By contrast, OPCs do not express MCT1 (Lee et al., 2012), and there is a lack of evidence showing the expression of other Gluts in OPCs. Therefore, ...
... through Glut1 (also known as SLC2A1) and MCT1, respectively (Hirrlinger and Nave, 2014; Morrison et al., 2013; Rinholm et al., 2011; Saab et al., 2013). By contrast, OPCs do not express MCT1 (Lee et al., 2012), and there is a lack of evidence showing the expression of other Gluts in OPCs. Therefore, ...
Full Text - Digital Access to Scholarship at Harvard
... Mitchell and Macklis, 2005). This is in striking contrast to the much more homogeneous population of corticospinal motor neurons, which are born at !E13.5, populate one layer (layer V) and a limited area (sensorimotor) of cortex and extend projections to the spinal cord (although with a range of spi ...
... Mitchell and Macklis, 2005). This is in striking contrast to the much more homogeneous population of corticospinal motor neurons, which are born at !E13.5, populate one layer (layer V) and a limited area (sensorimotor) of cortex and extend projections to the spinal cord (although with a range of spi ...
Motor Resonance Meets Motor Performance - Unitn
... 6), the cortical portion comprised behind the arcuate sulcus and below the spur (Figure 1). The authors employed a naturalistic experimental paradigm in which the activity of single neurons was recorded during the occurrence of spontaneous movements performed by the animals. In this way they define ...
... 6), the cortical portion comprised behind the arcuate sulcus and below the spur (Figure 1). The authors employed a naturalistic experimental paradigm in which the activity of single neurons was recorded during the occurrence of spontaneous movements performed by the animals. In this way they define ...
Channelrhodopsin
Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.