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DNA: Structure and Functions
DNA: Structure and Functions

... heat-inactivated S strain, mixed with the R strain, the bacteria would die. Thus there was some material in the heat-killed S strain that was responsible for "transforming“ the R strain into a lethal form. ...
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DNA Webquest - Jackson School District

... 1. When DNA is preparing for replication, what are the bonds that are broken to break it into two strands?__________________________________________________ 2. What enzyme is responsible for splitting the two strands? ____________________________________ 3. The splitting of the DNA starts at a place ...
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... Codominance- when both alleles of a gene are fully expressed. Ex- brown and white chicken mate and the chicks come out speckled or brown and white. There isn’t one more dominant than the other. Autosomes- chromosomes 1-22, they occur in your somatic cells / body cells. They are responsible for every ...
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7.1 DNA Structure

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Summer 2007

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... Worksheet Lesson 5: The discovery of DNA's structure We can't credit just one scientist with the discovery of the structure of DNA. It was the work of many different scientists who built on the work of others before them. In this activity you will be finding out about some of these scientists and th ...
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Cre-Lox recombination



In the field of genetics, Cre-Lox recombination is known as a site-specific recombinase technology, and is widely used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA modification to be targeted to a specific cell type or be triggered by a specific external stimulus. It is implemented both in eukaryotic and prokaryotic systems.The system consists of a single enzyme, Cre recombinase, that recombines a pair of short target sequences called the Lox sequences. This system can be implemented without inserting any extra supporting proteins or sequences. The Cre enzyme and the original Lox site called the LoxP sequence are derived from bacteriophage P1.Placing Lox sequences appropriately allows genes to be activated, repressed, or exchanged for other genes. At a DNA level many types of manipulations can be carried out. The activity of the Cre enzyme can be controlled so that it is expressed in a particular cell type or triggered by an external stimulus like a chemical signal or a heat shock. These targeted DNA changes are useful in cell lineage tracing and when mutants are lethal if expressed globally.The Cre-Lox system is very similar in action and in usage to the FLP-FRT recombination system.
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