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Restriction Enzymes - Solon City Schools
Restriction Enzymes - Solon City Schools

... In case you were curious … Restriction enzymes are named according to the following ...
Chapter 20
Chapter 20

... manipulation of organisms or their components to perform practical tasks or provide useful products ...
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Slide 1
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... Individual genes of DNA can be copied into mRNA. All DNA on a chromosome is copied before the cell divides. Now instead of one pair (times 23) of chromosomes, we have two pairs (times 23). 1) The chromosomes are copied. 2) The cell’s nuclear membrane disappears. 3) Two organelles called centrioles m ...
DNA Sequencing
DNA Sequencing

... 3. Aliquot C + Hydrazine, which modifies thymine + cytosine residues 4. Aliquot D + Hydrazine + 5 mol/l NaCl, which makes the reaction specific for cytosine ...
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... All living things are able to maintain stable internal conditions, whether they are single cells or complex, multicellular organisms. This property is called ______________________ When plant cells are placed in a salt solution, they don't shrink up in the same manner as do animal cells. This is due ...
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Biological Molecules Test Review Test covers carbohydrates, lipids

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Grade 10 – Reproduction and Genetics
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... sperm donation told the Times. "She's been in school with numerous kids who were born through donors. She's had crushes on boys who are donor children. It's become part of sex education." Also of concern is the fact that there are minimal regulations on who can or cannot donate sperm. Unlike in some ...
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Lec:1 Dr.Mohammed Alhamdany Molecular and genetic factors in

... • RNA is single-stranded. • The sugar residue within the nucleotide is ribose, rather than deoxyribose. • Uracil (U) is used in place of thymine (T). The nascent RNA molecule then undergoes a process called splicing , to generate an mRNA molecule which provides the template for protein production. F ...
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DNA Replication, Transcription, Translation Notes (Central Dogma)

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... • If the two alleles an organism has for a trait are the same, like GG, then the individual is said to be homozygous for that trait. If the alleles are different, Gg, the individual is said to be heterozygous. • The genetic makeup of an individual, the alleles it has, is called its genotype. The wa ...
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... Bacteria as vectors • Bacteria are used because they have plasmids • A plasmid is a circular piece of DNA that exists apart from the chromosome and replicates independently of it. ...
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... c. by coordination between conservedcysteine and histidine residues d. in an alpha helical region of theprotein. Homeodomain proteins: a. form a structure with three  sheets b. contact DNA primarily through  helix 3 and an N-terminal arm c. are similar in structure to prokaryotichelix-turn-helix p ...
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... 1(17+) was replaced with a Zeocin resistance cassette (ZeoR) which was amplified from pZeo4 (kindly provided by Martin Messerle, Hannover, Germany) with the primers ICP34.5zeo.for and ICP34.5zeo.rev (Table S1). The resulting virus was named HSV-1(17+)Lox-Luc-Δ134.5-Zeo or for short, HSV-Zeo. To co ...
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...  An enzyme isolated from a heat-loving bacterium is used to replicate the DNA when the appropriate nucleotides are added to the PCR machine  The machine replicates millions of copies of DNA in less than a day  Thermocycler are the copies of DNA cycled over and over again  This process is valuabl ...
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... techniques to coal gold nanoparticles with DNA strands • These DNA nano-particles bind together when an anthrax protective antigen appears ...
Intro to Genetics
Intro to Genetics

... Most organisms have TWO copies of every gene and chromosome (one from each parent) – see picture below Alleles are the different forms of a gene for a specific trait – Ex: flower color gene in pea plants contain a white allele and a purple allele ...
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Cre-Lox recombination



In the field of genetics, Cre-Lox recombination is known as a site-specific recombinase technology, and is widely used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA modification to be targeted to a specific cell type or be triggered by a specific external stimulus. It is implemented both in eukaryotic and prokaryotic systems.The system consists of a single enzyme, Cre recombinase, that recombines a pair of short target sequences called the Lox sequences. This system can be implemented without inserting any extra supporting proteins or sequences. The Cre enzyme and the original Lox site called the LoxP sequence are derived from bacteriophage P1.Placing Lox sequences appropriately allows genes to be activated, repressed, or exchanged for other genes. At a DNA level many types of manipulations can be carried out. The activity of the Cre enzyme can be controlled so that it is expressed in a particular cell type or triggered by an external stimulus like a chemical signal or a heat shock. These targeted DNA changes are useful in cell lineage tracing and when mutants are lethal if expressed globally.The Cre-Lox system is very similar in action and in usage to the FLP-FRT recombination system.
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