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- humans ingest more proteins than needed for replacement of
- humans ingest more proteins than needed for replacement of

... Branched-chain amino acid metabolic pathways - branched-chain amino acids  leucine, isoleucine, and valine (essential amino acids) - first step in their catabolism is reversible transamination  amino group transferred to alphaKG to form glutamate - second reaction  irreversible oxidative decarbox ...
PFK-2
PFK-2

... • Once oxaloacetate is produced, it is reduced to malate so that it can be transported to the cytosol. In the cytosol, oxaloacetate is subsequently dexcarboxylated/phosphorylated by PEPCK (phosphoenolpyruvate carboxykinase), a second enzyme unique to gluconeogenesis. The resulting phosphoenol pyruva ...
Tricarboxylic Acid Cycle (TCA), Krebs Cycle
Tricarboxylic Acid Cycle (TCA), Krebs Cycle

... The irreversibility of the reaction explains why glucose can not be formed from acetyl CoA in gluconeogenesis. ...
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... •  They increase the rate of a reaction (106 to 1012 times faster), but are unchanged themselves. •  Enzymes are very specific; each enzyme catalyzes a certain reaction or type of reaction only. •  The names of most enzymes end with the suffix -ase like peptidase, lipase, and hydrolase •  A cofactor ...
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Blood Glucose Concentration

... 1. Remove glucose from blood [primary and unique effect of insulin] ...
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Digestive System

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GLYCOLYSIS

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From: From one amino acid to another: tRNA

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aerobic respiration
aerobic respiration

... 3. These pathways regenerate NAD1, which the cells can use to keep glycolysis going to make more ATP in the absence of oxygen. 4. Without niacin or the ability to make it, the person would be deficient in NAD1. Since NAD1 is used in Step 3 of glycolysis, glycolysis would be inhibited. STRUCTURES AND ...
Contemporary Nutrition
Contemporary Nutrition

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Detailed Objectives

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Dietary Fat Composition Influences Tissue Lipid Profile and Gene

... this diet was developed several groups reported undesirable physiological effects linked to the diet, such as hemorrhagic deaths [2], nephrocalcinosis [3], and fatty liver [4]. An amended formulation of the diet (AIN-76A) was developed in 1980 with an increased vitamin K content to address the hemor ...
Clinical biochemistry
Clinical biochemistry

... IEM arises from a damaged gene which leads to abnormal enzyme.  May be autosomal or sex-linked.  May be recessive or dominant in expression.  Heterozygote will have both normal and abnormal alleles. But homozygote will have two alleles the same on each chromosome. ...
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... then serve as tool box for the rational redesign of Yarrowia’s lipid flux with modified b-oxidation, TAG biosynthesis and w-oxidation thus allowing for the production of lipid precursors or for their conversion into other added-value derivatives. Additional engineering efforts can further optimize a ...
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Notes on Biopolymers

... Myristoleic acid: CH3(CH2)3CH=CH(CH2)7COOH C14:1 Palmitoleic acid: CH3(CH2)5CH=CH(CH2)7COOH C16:1 Oleic acid: CH3(CH2)7CH=CH(CH2)7COOH C18:1 Linoleic acid: CH3(CH2)4CH=CHCH2CH=CH(CH2)7COOH C18:2 Alpha-linolenic acid: CH3CH2CH=CHCH2CH=CHCH2CH=CH(CH2)7COOH C18:3 Arachidonic acid CH3(CH2)4CH=CHCH2CH=CH ...
Biochemistry
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... early medical management. A dialogue with the department is encouraged and may expedite more complex investigations. General laboratory requirements are covered in SOP_GEN_003 Notes for guidance of staff using the biochemical services (non-metabolic investigations). This includes general information ...
Energy Systems
Energy Systems

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Detailed Objectives

... Indicate the name of any enzyme catalysts and cofactors for any specific reaction. Know the general reaction type. Understand the general enzyme mechanisms and intermediate structures for those specific reactions discussed in class. Understand the free energy considerations (production and use of AT ...
Quiz 15
Quiz 15

... 7. Which type of interaction stabilizes the alpha helix and the beta pleated sheet structures of proteins? A) hydrophobic interactions B) nonpolar covalent bonds C) ionic bonds D) hydrogen bonds E) peptide bonds 8. A hydrophilic R-group of an amino acid in hemoglobin would NOT be attracted to: A) t ...
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Chapter 5 - csmithbio
Chapter 5 - csmithbio

... Steroids • Steroids are lipids characterized by a carbon skeleton consisting of four fused rings • Cholesterol, an important steroid, is a component in animal cell membranes • Although cholesterol is essential in animals, high levels in the blood may contribute to cardiovascular disease ...
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Fatty acid metabolism

Fatty acids are a family of molecules classified within the lipid macronutrient class. One role of fatty acids within animal metabolism is energy production in the form of adenosine triphosphate (ATP) synthesis. When compared to other macronutrient classes (carbohydrates and protein), fatty acids yield the most ATP on an energy per gram basis by a pathway called β-oxidation. In addition, fatty acids are important for energy storage, phospholipid membrane formation, and signaling pathways. Fatty acid metabolism consists of catabolic processes that generate energy and primary metabolites from fatty acids, and anabolic processes that create biologically important molecules from fatty acids and other dietary sources.
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